https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 InsuTAG: a novel physiologically relevant predictor for insulin resistance and metabolic syndrome https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30774 Wed 11 Apr 2018 11:53:38 AEST ]]> Science behind the cardio-metabolic benefits of omega-3 polyunsaturated fatty acids: biochemical effects vs. clinical outcomes https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:35660 Wed 02 Oct 2019 13:05:55 AEST ]]> Differential effects of medium- and long-chain saturated fatty acids on blood lipid profile: a systematic review and meta-analysis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36475 18 y. Where possible, studies were pooled for meta-analysis using RevMan 5.2. The principle summary measure was the mean difference between groups calculated using the random-effects model. Results: Eleven eligible crossover and 1 parallel trial were identified with a total of 299 participants [weighted mean ± SD age: 38 ± 3 y; weighted mean ± SD body mass index (kg/m2): 24 ± 2]. All studies were pooled for the meta-analysis. Diets enriched with MCFAs led to significantly higher high-density lipoprotein (HDL) cholesterol concentrations than diets enriched with LCSFAs (0.11 mmol/L; 95% CI: 0.07, 0.15 mmol/L) with no effect on triglyceride, low-density lipoprotein (LDL) cholesterol, and total cholesterol concentrations. Consumption of diets rich in MCFAs significantly increased apolipoprotein A-I (apoA-I) concentrations compared with diets rich in LCSFAs (0.08 g/L; 95% CI: 0.02, 0.14 g/L). There was no evidence of statistical heterogeneity for HDL cholesterol, apoA-I, and triglyceride concentrations; however, significant heterogeneity was observed for the total cholesterol (I2 = 49%) and LDL cholesterol analysis (I2 = 58%). Conclusion: The findings of this research demonstrate a differential effect of MCFAs and LCSFAs on HDL cholesterol concentrations. Further investigations are warranted to elucidate the mechanism by which the lipid profile is altered. This trial was registered at www.crd.york.ac.uk/PROSPERO as CRD42017078277.]]> Tue 19 May 2020 13:02:08 AEST ]]> Do v-3 PUFAs affect insulin resistance in a sex-specific manner? A systematic review and meta-analysis of randomized controlled trials https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30070 Sat 24 Mar 2018 07:31:15 AEDT ]]> Sex-dependent association between erythrocyte n-3 PUFA and type 2 diabetes in older overweight people https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24609 trend=0·015). A similar but non-significant trend was seen in overweight men. After adjusting for BMI, no associations were found between n-3I and fasting blood glucose, HbA1c, insulin or HOMA-IR. In conclusion, higher erythrocyte n-3 PUFA status may be protective against the development of T2D in overweight women. Further research is warranted to determine whether dietary interventions that improve n-3 PUFA status can improve measures of IR, and to further elucidate sex-dependent differences.]]> Sat 24 Mar 2018 07:11:56 AEDT ]]> Curcumin alleviates postprandial glycaemic response in healthy subjects: A cross-over, randomized controlled study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36438 Mon 04 May 2020 12:30:03 AEST ]]>