/manager/Index ${session.getAttribute("locale")} 5 Genome-wide significant results identified for plasma apolipoprotein H levels in middle-aged and older adults /manager/Repository/uon:24759 -11). The results were replicated in an independent cohort, the Hunter Community Study (p < 0.002) (n = 313). Conditional and joint analysis (COJO) confirmed the association of the chromosomal 17 region with ApoH levels. The set of independent SNPs identified by COJO explained 23% of the variance. The relationships between the top SNPs and cardiovascular/lipid/cognition measures and diabetes were assessed in Sydney MAS, with suggestive results observed for diabetes and cognitive performance. However, replication of these results in the smaller OATS cohort was not found. This work provides impetus for future research to better understand the contribution of genetics to ApoH levels and its possible impacts on health.]]> Wed 11 Apr 2018 15:04:20 AEST ]]> Acute effects of a dietary non-starch polysaccharide supplement on cognitive performance in healthy middle-aged adults /manager/Repository/uon:23864 Sat 24 Mar 2018 07:13:38 AEDT ]]>