https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Telomere shortening in elderly individuals with mild cognitive impairment may be attenuated with ¿-3 fatty acid supplementation: a randomized controlled pilot study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:28807 65 y with MCI were randomized to receive a supplement rich in the long-chain ω-3 PUFAs eicosapentaenoic acid (EPA; 1.67 g EPA + 0.16 g docosahexaenoic acid DHA/d; n = 12) or DHA (1.55 g DHA + 0.40 g EPA/d; n = 12), versus ω-6 PUFA linoleic acid (LA; 2.2 g/d; n = 9) for 6 mo. Results: The intervention did not show an increase in telomere length with treatment and there was a trend toward telomere shortening during the intervention period. Linear mixed modeling produced a robust model although statistically underpowered. Telomere shortening was greatest in the LA group (d = 0.21) than in the DHA (d = 0.12) and EPA groups (d = 0.06). Increased erythrocyte DHA levels were associated with reduced telomere shortening (r = −0.67; P = 0.02) in the DHA group. Conclusion: Telomeric shortening may be attenuated by ω-3 PUFA supplementation, requiring further investigation in larger samples.]]> Sat 24 Mar 2018 07:38:26 AEDT ]]> Increased erythrocyte eicosapentaenoic acid and docosahexaenoic acid are associated with improved attention and behavior in children with adhd in a randomized controlled three-way crossover trial https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26499 Diagnostic and Statistical Manual of Mental Disorders (4th ed.; DSM-IV) hyperactivity (r = -.270, p =.002) and DSM-IV inattention (r = -.343, p <.001). Conclusion: Increasing erythrocyte DHA and EPA via dietary supplementation may improve behavior, attention, and literacy in children with ADHD.]]> Sat 24 Mar 2018 07:35:36 AEDT ]]>