https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Aldehyde dehydrogenase plays a pivotal role in the maintenance of stallion sperm motility https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29909 P < 0.001) were found between ALDH expression and various motility parameters of stallion spermatozoa including the percentage of progressive (r = 0.79) and rapidly motile (r = 0.79) spermatozoa, whereas repeated measurements over 24 h revealed highly significant correlations among progressive motility loss, 4HNE accumulation, and ALDH expression (P ≤ 0.001). ALDH inhibition resulted in a spontaneous increase in 4HNE levels in viable cells (21.1 ± 5.8% vs. 42.6 ± 5.2%; P ≤ 0.05) and a corresponding decrease in total motility (41.7 ± 6.2% vs. 6.4 ± 2.6%; P ≤ 0.001) and progressive motility (17.0 ± 4.1% vs. 0.7 ± 0.4%; P ≤ 0.001) of stallion spermatozoa over 24 h. Similarly, inhibition of ALDH in 4HNE-challenged spermatozoa significantly reduced total motility over 4 h (35.4 ± 9.7% vs. 15.3 ± 5.1%, respectively; P ≤ 0.05). This study contributes valuable information about the role of the ALDH enzymes in the maintenance of stallion sperm functionality, with potential diagnostic and in vitro applications for assisted reproductive technologies.]]> Wed 11 Apr 2018 16:45:10 AEST ]]> L-carnitine and pyruvate are prosurvival factors during the storage of stallion spermatozoa at room temperature https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26316 Wed 11 Apr 2018 09:24:47 AEST ]]> The paradoxical relationship between stallion fertility and oxidative stress https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19260 Sat 24 Mar 2018 08:06:38 AEDT ]]> Capacitation in the presence of methyl-β-cyclodextrin results in enhanced zona pellucida-binding ability of stallion spermatozoa https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:18685 Sat 24 Mar 2018 08:01:06 AEDT ]]> Sperm motility is lost in vitro as a consequence of mitochondrial free radical production and the generation of electrophilic aldehydes but can be significantly rescued by the presence of nucleophilic thiols https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21182 Sat 24 Mar 2018 07:56:06 AEDT ]]> Investigation of the stallion sperm proteome by mass spectrometry https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27065 Sat 24 Mar 2018 07:25:20 AEDT ]]>