https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 The velocity of collateral filling predicts recanalization in acute ischemic stroke after intravenous thrombolysis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29190 p = 0.020), but not tMIP-ASPECT score (OR = 1.073, 95% CI = 0.820–1.405, p = 0.607), was independently associated with recanalization (AOL score of 2 and 3) at 24 hours after IVT. When recanalization was achieved, hemorrhagic transformation (HT) occurred more frequently in patients with slow collaterals (ATD ≥ 2.3 seconds) than those with rapid collaterals (ATD < 2.3 seconds) (88.9% vs 38.1%, p = 0.011). In conclusion, the velocity of collaterals related to recanalization, which may guide the decision-making of revascularization therapy in acute ischemic stroke.]]> Wed 11 Apr 2018 13:32:16 AEST ]]> Absent filling of ipsilateral superficial middle cerebral vein is associated with poor outcome after reperfusion therapy https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30493 2; odds ratio, 2.710; P=0.040). No difference was found in reperfusion rate after treatment between patients with and without SMCV-(P > 0.05). In patients achieving major reperfusion (=80%), there was no difference in 24-hour infarct volume, or rate of poor outcome between patients with and without SMCV-(P > 0.05). However, in those without major reperfusion, patients with SMCV-had larger 24-hour infarct volume (P=0.011), higher rate of poor outcome (P=0.012), and death (P=0.032) compared with those with SMCV filling. SMCV-was significantly associated with brain edema at 24 hours (P=0.037), which, in turn, was associated with poor 3-month outcome (P=0.002). Conclusions: Lack of SMCV filling contributed to poor outcome after thrombolysis, especially when reperfusion was not achieved. The main deleterious effect of poor venous filling appears related to the development of brain edema.]]> Thu 28 Oct 2021 13:03:14 AEDT ]]>