https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Science behind the cardio-metabolic benefits of omega-3 polyunsaturated fatty acids: biochemical effects vs. clinical outcomes https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:35660 Wed 02 Oct 2019 13:05:55 AEST ]]> Differential effects of medium- and long-chain saturated fatty acids on blood lipid profile: a systematic review and meta-analysis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36475 18 y. Where possible, studies were pooled for meta-analysis using RevMan 5.2. The principle summary measure was the mean difference between groups calculated using the random-effects model. Results: Eleven eligible crossover and 1 parallel trial were identified with a total of 299 participants [weighted mean ± SD age: 38 ± 3 y; weighted mean ± SD body mass index (kg/m2): 24 ± 2]. All studies were pooled for the meta-analysis. Diets enriched with MCFAs led to significantly higher high-density lipoprotein (HDL) cholesterol concentrations than diets enriched with LCSFAs (0.11 mmol/L; 95% CI: 0.07, 0.15 mmol/L) with no effect on triglyceride, low-density lipoprotein (LDL) cholesterol, and total cholesterol concentrations. Consumption of diets rich in MCFAs significantly increased apolipoprotein A-I (apoA-I) concentrations compared with diets rich in LCSFAs (0.08 g/L; 95% CI: 0.02, 0.14 g/L). There was no evidence of statistical heterogeneity for HDL cholesterol, apoA-I, and triglyceride concentrations; however, significant heterogeneity was observed for the total cholesterol (I2 = 49%) and LDL cholesterol analysis (I2 = 58%). Conclusion: The findings of this research demonstrate a differential effect of MCFAs and LCSFAs on HDL cholesterol concentrations. Further investigations are warranted to elucidate the mechanism by which the lipid profile is altered. This trial was registered at www.crd.york.ac.uk/PROSPERO as CRD42017078277.]]> Tue 19 May 2020 13:02:08 AEST ]]> Improvement of the omega 3 index of healthy subjects does not alter the effects of dietary saturated fats or n-6PUFA on LDL profiles https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32707 Thu 12 Jul 2018 11:51:23 AEST ]]> Postprandial lipid responses do not differ following consumption of butter or vegetable oil when consumed with omega-3 polyunsaturated fatty acids https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27700 Sat 24 Mar 2018 07:40:10 AEDT ]]> Kinetics of omega-3 polyunsaturated fatty acids when co-administered with saturated or omega-6 fats https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22886 Sat 24 Mar 2018 07:15:19 AEDT ]]> Curcumin alleviates postprandial glycaemic response in healthy subjects: A cross-over, randomized controlled study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36438 Mon 04 May 2020 12:30:03 AEST ]]>