https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Plasmacytoid dendritic cells promote host defense against acute pneumovirus infection via the TLR7-MyD88-dependent signaling pathway https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:13276 + T cell cytokine production was abrogated. The adoptive transfer of TLR7-sufficient, but not TLR7-deficient pDC to TLR7 gene-deleted mice recapitulated the antiviral responses observed in wild-type mice and promoted virus clearance. In summary, TLR7-mediated signaling by pDC is required for appropriate innate responses to acute pneumovirus infection. It is conceivable that as-yet–unidentified defects in the TLR7 signaling pathway may be associated with elevated levels of RSV-associated morbidity and mortality among otherwise healthy human infants.]]> Sat 24 Mar 2018 08:15:16 AEDT ]]> Toll-like receptor 7 gene deficiency and early-life Pneumovirus infection interact to predispose toward the development of asthma-like pathology in mice https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20102 Sat 24 Mar 2018 08:00:09 AEDT ]]> Antigen-specific T-cell responses to a recombinant fowlpox virus are dependent on MyD88 and Interleukin-18 and independent of toll-like Receptor 7 (TLR7)- and TLR9-mediated innate immune recognition https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:17737 Sat 24 Mar 2018 07:57:39 AEDT ]]> Guidelines for the use and interpretation of assays for monitoring autophagy https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30350 Sat 24 Mar 2018 07:40:25 AEDT ]]> Guidelines for the use and interpretation of assays for monitoring autophagy https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22060 Sat 24 Mar 2018 07:11:40 AEDT ]]>