A common variant at the 14q32 endometrial cancer risk locus activates AKT1 through YY1 binding

- Painter, Jodie N., Kaufmann, Susanne, Hoivik, Erling A., Goode, Ellen L., Scott, Rodney J., Tomlinson, Ian, Dunning, Alison M., Easton, Douglas F., French, Juliet D., Salvesen, Helga B., Pollock, Pamela M., Thompson, Deborah J., O'Mara, Tracy A., Spurdle, Amanda B., Edwards, Stacey L., Hillman, Kristine M., Sivakumaran, Haran, Darabi, Hatef, Cheng, Timothy H.T., Pearson, John, Kazakoff, Stephen, Waddell, Nicola

A Menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia

- Krivtsov, Andrei V., Evans, Kathryn, McDermott, Lisa, Jones, Connor D., Jing, Duohui, Braytee, Ali, Chacon, Diego, Earley, Eric, McKeever, Brian M., Claremon, David, Gifford, Andrew J., Lee, Heather J., Gadrey, Jayant Y., Teicher, Beverley A., Pimanda, John E., Beck, Dominik, Perry, Jennifer A., Smith, Malcolm A., McGeehan, Gerard M., Lock, Richard B., Armstrong, Scott A., Eschle, Benjamin K., Hatton, Charlie, Uckelmann, Hannah J., Ross, Kenneth N., Perner, Florian, Olsen, Sarah N., Pritchard, Tara

A recurrent De Novo nonsense variant in ZSWIM6 results in severe intellectual disability without frontonasal or limb malformations

- Palmer, Elizabeth E., Kumar, Raman, Oufadem, Myriam, Lalani, Seema R., Lewis, Andrea M., Xia, Fan, Tam, Allison, Webster, Richard, Brammah, Susan, Filippini, Francesca, Pollard, John, Spies, Judy, Gordon, Christopher T., Minoche, Andre E., Cowley, Mark J., Risen, Sarah, Powell-Hamilton, Nina N., Tusi, Jessica E., Immken, LaDonna, Nagakura, Honey, Bole-Feysot, Christine, Nitschké, Patrick, Garrigue, Alexandrine, Shaw, Marie, de Saint Basile, Geneviève, Kivuva, Emma, Scott, Richard H., Rendon, Augusto, Munnich, Arnold, Newman, William, Kerr, Bronwyn, Besmond, Claude, Rosenfeld, Jill A., Amiel, Jeanne, Hubert, Laurence, Field, Michael, Gecz, Jozef, Carroll, Renee, Rio, Marlène, Murray, Lucinda, Leffler, Melanie, Dudding-Byth, Tracy

Adult cardiac-resident MSC-like stem cells with a proepicardial origin

- Chong, James J. H., Chandrakanthan, Vashe, Biben, Christine, Zoellner, Hans, Colvin, Emily K., Pimanda, John E., Biankin, Andrew V., Zhou, Bin, Pu, William T., Prall, Owen W. J., Harvey, Richard P., Xaymardan, Munira, Asli, Naisana S., Li, Joan, Ahmed, Ishtiaq, Heffernan, Corey, Menon, Mary K., Scarlett, Christopher J., Rashidianfar, Amirsalar

Amygdala NPY circuits promote the development of accelerated obesity under chronic stress conditions

- Ip, Chi K., Zhang, Lei, Begg, Denovan, Brüning, Jens C., Lee, Nicola J., Hernandez-Sanchez, Diana, Gopalasingam, Gopana, Koller, Julia, Tasan, Ramon, Sperk, Günther, Herzog, Herbert, Farzi, Aitak, Qi, Yue, Clarke, Ireni, Reed, Felicia, Shi, Yan-Chuan, Enriquez, Ronaldo, Dayas, Chris, Graham, Bret

An immune atlas of clear cell renal cell carcinoma

- Chevrier, Stephane, Levine, Jacob Harrison, van den Broek, Maries, Beisel, Christian, Stadler, Michael Beda, Gedye, Craig, Reis, Bernhard, Pe'er, Dana, Bodenmiller, Bernd, Zanotelli, Vito Riccardo Tomaso, Silina, Karina, Schulz, Daniel, Bacac, Marina, Ries, Carola Hermine, Ailles, Laurie, Jewett, Michael Alexander Spencer, Moch, Holger

Assembly rules of reef corals are flexible along a steep climatic gradient

- Hughes, Terry P., Baird, Andrew H., Dinsdale, Elizabeth A., Moltschaniwskyj, Natalie A., Pratchett, Morgan S., Tanner, Jason E., Willis, Bette L.

Australian Brain Alliance

- Richards, L. R., Michie, P. T., Hickie, I. B., Mattingley, J. B., Schofield, P. R., Shum, D. H. K., Stuart, G. J., Vickers, J. C., Vissel, B., Badcock, D. R., Bartlett, P. F., Bekkers, J. M., Bourne, J. A., Castles, A., Egan, G. F., Fornito, A., Hannan, A. J.

Bi-allelic recessive loss-of-function variants in FANCM cause non-obstructive azoospermia

- Kasak, Laura, Punab, Margus, Smith, Lee B., Conrad, Donald F., Laan, Maris, Nagirnaja, Liina, Grigorova, Marina, Minajeva, Ave, Lopes, Alexandra M., Punab, Anna Maria, Aston, Kenneth I., Carvalho, Filipa, Laasik, Eve

Bioinformatics-based identification of expanded repeats:a non-reference intronic pentamer expansion in RFC1 causes CANVAS

- Rafehi, Haloom, Szmulewicz, David J., Barcina, Maria Garcia, Breen, David P., Chancellor, Andrew M., Cremer, Phillip D., Delatycki, Martin B., Fogel, Brent L., Hackett, Anna, Halmagyi, G. Michael, Kapetanovic, Solange, Lang, Anthony, Bennett, Mark F., Mossman, Stuart, Mu, Weiyi, Patrikios, Peter, Perlman, Susan L., Rosemergy, Ian, Storey, Elsdon, Watson, Shaun R. D., Wilson, Michael A., Zee, David S., Valle, David, Sobreira, Nara L. M., Amor, David J., Bahlo, Melanie, Lockhart, Paul J., Pope, Kate, Smith, Katherine R., Gillies, Greta, Diakumis, Peter, Dolzhenko, Egor, Eberle, Michael A.

Ca²⁺ oscillations promote APC/C-dependent cyclin B1 degradation during metaphase arrest and completion of meiosis in fertilizing mouse eggs

- Nixon, Victoria L., Levasseur, Mark, McDougall, Alex, Jones, Keith T.

Control of sarcoplasmic reticulum Ca²⁺ release by stochastic RyR gating within a 3D model of the cardiac dyad and importance of induction decay for CICR termination

- Cannell, M. B., Kong, C. H. T., Imtiaz, M. S., Laver, D. R.

DNA polymerase epsilon deficiency causes IMAGe syndrome with variable immunodeficiency

- Logan, Clare V., Murray, Jennie E., Parry, David A., Robertson, Andrea, Bellelli, Roberto, Tarnauskaitė, Žygimantė, Challis, Rachel, Cleal, Louise, Borel, Valerie, Fluteau, Adeline, Santoyo-Lopez, Javier, Aitman, Timothy J., Biankin, Andrew V., Cooke, Susanna L., Humphrey, Wendy Inglis, Martin, Sacha, Mennie, Lynne, Meynert, Alison, Miedzybrodzka, Zosia, Murphy, Fiona, Goel, Himanshu

Genome analyses of >200,000 individuals identify 58 loci for chronic inflammation and highlight pathways that link inflammation and complex disorders

- Ligthart, Symen, Vaez, Ahmad, Võsa, Urmo, Stathopoulou, Maria G., de Vries, Paul S., Prins, Bram P., Van der Most, Peter J., Tanaka, Toshiko, Naderi, Elnaz, Rose, Lynda M., Wu, Ying, Karlsson, Robert, Barbalic, Maja, Lin, Honghuang, Pool, René, Zhu, Gu, Macé, Aurélien, Sidore, Carlo, Trompet, Stella, Mangino, Massimo, Sabater-Lleal, Maria, Oldmeadow, Christopher, Holliday, Elizabeth G., Attia, John R., Scott, Rodney J., McEvoy, Mark

Genome-scale oscillations in DNA methylation during exit from pluripotency

- Rulands, Steffen, Lee, Heather J., Kelsey, Gavin, Stegle, Oliver, Simons, Benjamin D., Reik, Wolf, Clark, Stephen J., Angermueller, Christof, Smallwood, Sébastien A., Krueger, Felix, Mohammed, Hisham, Dean, Wendy, Nichols, Jennifer, Rugg-Gunn, Peter

Germline de novo mutations in GNB1 cause severe neurodevelopmental disability, hypotonia, and seizures

- Petrovski, Slavé, Kury, Sébastien, Besnard, Thomas, Becraft, Emily, Wadley, Alexandrea, Politi, Anya Revah, Colombo, Sophie, Zhu, Xiaolin, Ren, Zhong, Andrews, Ian, Dudding-Byth, Tracy, Schneider, Amy L., Myers, Candace T., Anyane-Yeboa, Kwame, Cogné, Benjamin, Bialer, Martin, Xia, Fan, Hemati, Parisa, Riviello, James, Mehaffey, Michele

HOW is required for stem cell maintenance in the drosophila testis and for the onset of transit-amplifying divisions

- Monk, Adrian C., Siddall, Nicole A., Volk, Talila, Fraser, Barbara, Quinn, Leonie M., McLaughlin, Eileen A., Hime, Gary R.

In Vivo cell fate tracing provides no evidence for mesenchymal to epithelial transition in adult fallopian tube and uterus

- Ghosh, Arnab, Syed, Shafiq M., Kumar, Manish, Carpenter, Tyler J., Teixeira, Jose M., Houairia, Nathaniel, Negi, Sumedha, Tanwar, Pradeep S.

Lateral hypothalamic GABAergic neurons encode reward predictions that are relayed to the ventral tegmental area to regulate learning

- Sharpe, Melissa J., Marchant, Nathan J., Pickel, James, Smith, Jeffrey C., Niv, Yael, Shaham, Yavin, Harvey, Brandon K., Schoenbaum, Geoffrey, Whitaker, Leslie R., Richie, Christopher T., Zhang, Yajun J., Campbell, Erin J., Koivula, Pyry P., Necarsulmer, Julie C., Mejias-Aponte, Carlos, Morales, Marisela

Modeling linkage disequilibrium increases accuracy of polygenic risk scores

- Vilhjálmsson, Bjarni J., Yang, Jian, Hayeck, Tristan, Won, Hong-Hee, Schizophrenia Working Group of the Psychiatric Genomics Consortium,, Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE) study,, Finucane, Hilary K., Gusev, Alexander, Lindström, Sara, Ripke, Stephan, Genovese, Giulio, Loh, Po-Ru, Bhatia, Gaurav, Do, Ron