Tumor necrosis factor-related apoptosis-inducing ligand regulates hallmark features of airways remodeling in allergic airways disease

- Collison, Adam, Li, Junyao, Pereira de Siqueira, Ana, Zhang, Jie, Toop, Hamish D., Morris, Jonathan C., Foster, Paul S., Mattes, Joerg

Transcription factor p63 regulates key genes and wound repair in human airway epithelial basal cells

- Warner, Stephanie M. B., Hackett, Tillie-Louise, Shaheen, Furquan, Hallstrand, Teal S., Kicic, Anthony, Stick, Stephen M., Knight, Darryl A.

Toll/IL-1 signaling is critical for house dust mite-specific Th1 and Th2 responses

- Phipps, Simon, Lam, Chuan En, Mansell, Ashley, Matthaei, Klaus I., Foster, Paul S., Kaiko, Gerard E., Foo, Shen Yun, Collison, Adam, Mattes, Joerg, Barry, Jessica, Davidson, Sophia, Oreo, Kevin, Smith, Lauren

Toll-like receptor 7 is reduced in severe asthma and linked to an altered microRNA profile

- Rupani, Hitasha, Martinez-Nunez, Rocio T., Dennison, Patrick, Lau, Laurie C. K., Jayasekera, Nivenka, Havelock, Tom, Francisco-Garcia, Ana S., Grainge, Christopher, Howarth, Peter H., Sanchez-Elsner, Tilman

Theophylline represses IL-8 secretion from airway smooth muscle cells independently of phosphodiesterase inhibition: novel role as a protein phosphatase 2A activator

- Patel, Brijeshkumar S., Rahman, Md. Mostafizur, Rumzhum, Nowshin N., Oliver, Brian G., Verrills, Nicole M., Ammit, Alaina J.

The nucleotide-binding domain, leucine-rich repeat protein 3 inflammasome/IL-1 receptor I axis mediates innate, but not adaptive, immune responses after exposure to particulate matter under 10 µm

- Hirota, Jeremy A., Gold, Matthew J., McNagny, Kelly M., Knight, Darryl A., Hiebert, Paul R., Parkinson, Leigh G., Wee, Tracee, Smith, Dirk, Hansbro, Phil M., Carlsten, Chris, VanEeden, Stephen, Sin, Don D.

The effect of inhaled IFN-β on worsening of asthma symptoms caused by viral infections: a randomized trial

- Djukanovic, Ratko, Harrison, Tim, Marsden, Richard, Boxall, Christine, Dudley, Sarah, Plagnol, Vincent, Holgate, Stephen T., Monk, Phillip, INTERCIA Study Group,, Johnston, Sebastian L., Gabbay, Flic, Wark, Peter, Thomson, Neil C., Niven, Robert, Singh, Dave, Reddel, Helen K., Davies, Donna E.

The coagulant factor Xa induces protease-activated receptor-1 and annexin A2-dependent airway smooth muscle cytokine production and cell proliferation

- Schuliga, Michael, Royce, Simon G., Langenbach, Shenna, Berhan, Asres, Harris, Trudi, Keenan, Christine R., Stewart, Alastair G.

Targeting PI3K-p110α suppresses influenza virus infection in chronic obstructive pulmonary disease

- Hsu, Alan Chen-Yu, Starkey, Malcolm R., Wark, Peter A., Hansbro, Philip M., Hanish, Irwan, Parsons, Kristy, Haw, Tatt Jhong, Howland, Linda J., Barr, Ian, Mahony, James B., Foster, Paul S., Knight, Darryl A.

Targeting interleukin-13 with tralokinumab attenuates lung fibrosis and epithelial damage in a humanized SCID idiopathic pulmonary fibrosis model

- Murray, Lynne A., Zhang, Huilan, Sleeman, Matthew A., Herzog, Erica L., Hogaboam, Cory M., Oak, Sameer R., Coelho, Ana Lucia, Herath, Athula, Flaherty, Kevin R., Lee, Joyce, Bell, Matt, Knight, Darryl A., Martinez, Fernando J.

Steroid-resistant neutrophilic inflammation in a mouse model of an acute exacerbation of asthma

- Ito, Kazuhiro, Herbert, Cristan, Siegle, Jessica S., Vuppusetty, Chaitanya, Hansbro, Nicole, Thomas, Paul S., Foster, Paul S., Barnes, Peter J., Kumar, Rakesh K.

STAT3 regulates the onset of oxidant-induced senescence in lung fibroblasts

- Waters, David W., Blokland, Kaj E. C., Pathinayake, Prabuddha S., Wei, Lan, Schuliga, Michael, Jaffar, Jade, Westall, Glen P., Hansbro, Philip M., Prele, Cecilia M., Mutsaers, Steven E., Bartlett, Nathan W., Burgess, Janette K., Grainge, Christopher L., Knight, Darryl A.

Role for NLRP3 inflammasome-mediated, IL-1ß-dependent responses in severe, steroid-resistant asthma

- Kim, Richard Y., Pinkerton, James W., Hirota, Jeremy A., Wood, Lisa G., Simpson, Jodie L., Knight, Darryl A., Wark, Peter A., Gibson, Peter G., O'Neill, Luke A. J., Cooper, Matthew A., Horvat, Jay C., Hansbro, Philip M., Essilfie, Ama T., Robertson, Avril A. B., Baines, Katherine J., Brown, Alexandra C., Mayall, Jemma R., Ali, M. Khadem, Starkey, Malcolm R., Hansbro, Nicole G.

Rhinovirus-induced CCL17 and CCL22 in asthma exacerbations and differential regulation by STAT6

- Williams, Teresa C., Jackson, David J., Maltby, Steven, Walton, Ross P., Ching, Yee-Mann, Glanville, Nicholas, Singanayagam, Ara, Brewins, Jennifer J., Clarke, Deborah, Hirsman, Aurica G., Loo, Su-Ling, Wei, Lan, Beale, Janine E., Casolari, Paolo, Caramori, Gaetano, Papi, Alberto, Belvisi, Maria, Wark, Peter A. B., Johnston, Sebastian L., Edwards, Michael R., Bartlett, Nathan W.

RelB-deficient dendritic cells promote the development of spontaneous allergic airway inflammation

- Nair, Prema M., Starkey, Malcolm R., Haw, Tatt Jhong, Ruscher, Roland, Liu, Gang, Maradana, Muralidhara R., Thomas, Ranjeny, O'Sullivan, Brendan J., Hansbro, Philip M.

Relative hypotension and adverse kidney-related outcomes among critically ill patients with shock a multicenter, prospective cohort study

- Panwar, Rakshit, Tarvade, Sanjay, Lanyon, Nicholas, Saxena, Manoj, Bush, Dustin, Hardie, Miranda, Attia, John, Bellomo, Rinaldo, Van Haren, Frank

Reduction of tumstatin in asthmatic airways contributes to angiogenesis, inflammation, and hyperresponsiveness

- Burgess, Janette K., Boustany, Sarah, Black, Judith L., Oliver, Brian G., Moir, Lyn M., Weckmann, Markus, Lau, Justine Y., Grafton, Karryn, Baraket, Melissa, Hansbro, Philip M., Hansbro, Nicole G., Foster, Paul S.

Randomized trial of a decision aid for patients with cystic fibrosis considering lung transplantation

- Vandemheen, Katherine L., O'Connor, Annette, Brager, Nancy, Rabin, Harvey, Morrison, Nancy, Gibson, Peter, Jackson, Mary, Paterson, Nigel, Middleton, Peter, Aaron, Shawn D., Bell, Scott C., Freitag, Andreas, Bye, Peter, Jeanneret, Alphonse, Berthiaume, Yves, Brown, Neil, Wilcox, Pearce, Ryan, Gerard

Pulmonary immunity during respiratory infections in early life and the development of severe asthma

- Hansbro, Philip M., Starkey, Malcolm R., Mattes, Joerg, Horvat, Jay C.

PD-L1 promotes early-life chlamydia respiratory infection-induced severe allergic airway disease

- Starkey, Malcolm R., Nguyen, Duc H., Brown, Alexandra C., Essilfie, Ama-Tawiah, Kim, Richard Y., Yagita, Hideo, Horvat, Jay C., Hansbro, Philip M.