A variant at 9p21.3 functionally implicates CDKN2B in paediatric B-cell precursor acute lymphoblastic leukaemia aetiology.

- Hungate, Eric A., Vora, Sapana R., Rudant, Jéremie, Orsi, Laurent, Clavel, Jacqueline, Milne, Elizabeth, Scott, Rodney J., Pui, Ching-Hon, Cox, Nancy J., Loh, Mignon L., Yang, Jun J., Skol, Andrew D., Gamazon, Eric R., Onel, Kenan, Moriyama, Takaya, Best, Timothy, Hulur, Imge, Lee, Younghee, Evans, Tiffany-Jane, Ellinghaus, Eva, Stanulla, Martin

c-Myc inactivation of p53 through the pan-cancer lncRNA MILIP drives cancer pathogenesis

- Feng, Yu Chen, Liu, Xiao Ying, Teng, Liu, Ji, Qiang, Wu, Yongyan, Li, Jin Ming, Gao, Wei, Zhang, Yuan Yuan, La, Ting, Tabatabaee, Hessam, Yan, Xu Guang, Jamaluddin, M. Fairuz B., Zhang, Didi, Guo, Su Tang, Scott, Rodney J., Liu, Tao, Thorne, Rick F., Zhang, Xu Dong, Jin, Lei

Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases

- Iglesias, Adriana I., Mishra, Aniket, Vitart, Veronique, Bykhovskaya, Yelena, Höhn, René, Springelkamp, Henriët, Cuellar-Partida, Gabriel, Gharahkhani, Puya, Bailey, Jessica N. Cooke, Willoughby, Colin E., Li, Xiaohui, Yazar, Seyhan, Nag, Abhishek, Khawaja, Anthony P., Polašek, Ozren, Siscovick, David, Mitchell, Paul, Tham, Yin Chung, Haines, Jonathan L., Kearns, Lisa S., Hayward, Caroline, Shi, Yuan, van Leeuwen, Elisabeth M., Taylor, Kent D., Wang, Jie Jin, Rochtchina, Elena, Attia, John, Scott, Rodney, Holliday, Elizabeth G., Baird, Paul N., Xie, Jing, Inouye, Michael, Viswanathan, Ananth, Sim, Xueling, Bonnemaijer, Pieter, Rotter, Jerome I., Martin, Nicholas G., Zeller, Tanja, Mills, Richard A., Staffieri, Sandra E., Jonas, Jost B., Schmidtmann, Irene, Boutin, Thibaud, Kang, Jae H., Lucas, Sionne E. M., Wong, Tien Yin, Beutel, Manfred E., Wilson, James F., Allingham, R. Rand, Brilliant, Murray H., Budenz, Donald L., Christen, William G., Fingert, John, Friedman, David S., Gaasterland, Douglas, Gaasterland, Terry, Hauser, Michael A., Kraft, Peter, Lee, Richard K., Lichter, Paul R., Liu, Yutao, Loomis, Stephanie J., Moroi, Sayoko E., Pericak-Vance, Margaret A., Realini, Anthony, Richards, Julia E., Schuman, Joel S., Scott, William K., Singh, Kuldev, Sit, Arthur J., Vollrath, Douglas, Weinreb, Robert N., Wollstein, Gadi, Zack, Donald J., Zhang, Kang

Diminished hERG K+ channel activity facilitates strong human labour contractions but is dysregulated in obese women

- Parkington, Helena C., Stevenson, Janet, Tonta, Mary A., Paul, Jonathan, Butler, Trent, Maiti, Kaushik, Chan, Eng-Cheng, Sheehan, Penelope M., Brennecke, Shaun P., Coleman, Harold A., Smith, Roger

Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy

- To, Eunice E., Vlahos, Ross, Starkey, Malcolm R., van der Sluis, Renee, Lewin, Sharon R., Bozinovski, Steven, O'Neill, Luke A. J., Quach, Tim, Porter, Christopher J. H., Brooks, Doug A., O'Leary, John J., Selemidis, Stavros, Luong, Raymond, Halls, Michelle L., Reading, Patrick C., King, Paul T., Chan, Christopher, Drummond, Grant R., Sobey, Christopher G., Broughton, Brad R. S.

Epigenetically reprogrammed methylation landscape drives the DNA self-assembly and serves as a universal cancer biomarker

- Ibn Sina, Abu Ali, Carrascosa, Laura G., Korbie, Darren, Trau, Matt, Liang, Ziyu, Grewal, Yadveer S., Wardiana, Andri, Shiddiky, Muhammad J. A., Gardiner, Robert A., Samaratunga, Hemamali, Gandhi, Maher K., Scott, Rodney J.

Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites

- Thorburn, Alison N., McKenzie, Craig I., Chevalier, Nina, Tan, Jian K., Marinõ, Eliana, Moore, Rob J., Wong, Lee, McConville, Malcolm J., Tull, Dedreia L., Wood, Lisa G., Murphy, Vanessa E., Mattes, Joerg, Shen, Sj, Gibson, Peter G., MacKay, Charles R., Stanley, Dragana, MacIa, Laurence, Mason, Linda J., Roberts, Laura K., Wong, Connie H. Y., Shim, Raymond, Robert, Remy

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

- Pattaro, Cristian, Teumer, Alexander, Taliun, Daniel, Wallaschofski, Henri, Vöelzke, Henry, Brenner, Hermann, Kroemer, Heyo K., Kramer, Holly, Lin, Honghuang, Leach, I. Mateo, Ford, Ian, Guessous, Idris, Rudan, Igor, Olden, Matthias, Prokopenko, Inga, Borecki, Ingrid, Heid, Iris M., Kolcic, Ivana, Persico, Ivana, Jukema, J. Wouter, Wilson, James F., Felix, Janine F., Divers, Jasmin, Lambert, Jean-Charles, Foster, Meredith, Stafford, Jeanette M., Gaspoz, Jean-Michel, Smith, Jennifer A., Faul, Jessica D., Wang, Jie Jin, Ding, Jingzhong, Hirschhorn, Joel N., Attia, John, Whitfield, John B., Chalmers, John, Yang, Qiong, Viikari, Jorma, Coresh, Josef, Denny, Joshua C., Karjalainen, Juha, Fernandes, Jyotika K., Endlich, Karlhans, Butterbach, Katja, Keene, Keith L., Lohman, Kurt, Portas, Laura, Chen, Ming-Huei, Launer, Lenore J., Lyytikäinen, Leo-Pekka, Yengo, Loic, Franke, Lude, Ferrucci, Luigi, Rose, Lynda M., Kedenko, Lyudmyla, Rao, Madhumathi, Struchalin, Maksim, Kleber, Marcus E., Pers, Tune H., Cavalieri, Margherita, Haun, Margot, Cornelis, Marilyn C., Ciullo, Marina, Pirastu, Mario, de Andrade, Mariza, McEvoy, Mark A., Woodward, Mark, Adam, Martin, Cocca, Massimiliano, Johnson, Andrew D., Nauck, Matthias, Imboden, Medea, Waldenberger, Melanie, Pruijm, Menno, Metzger, Marie, Stumvoll, Michael, Evans, Michele K., Sale, Michele M., Käehöenen, Mika, Boban, Mladen, Ko, Yi-An, Bochud, Murielle, Rheinberger, Myriam, Verweij, Niek, Bouatia-Naji, Nabila, Martin, Nicholas G., Hastie, Nick, Probst-Hensch, Nicole, Soranzo, Nicole, Devuyst, Olivier, Raitakari, Olli, Fuchsberger, Christian, Gottesman, Omri, Franco, Oscar H., Polasek, Ozren, Gasparini, Paolo, Munroe, Patricia B., Ridker, Paul M., Mitchell, Paul, Muntner, Paul, Meisinger, Christa, Smit, Johannes H., Tayo, Bamidele, Kovacs, Peter, Wild, Philipp S., Froguel, Philippe, Rettig, Rainer, Mäegi, Reedik, Biffar, Reiner, Schmidt, Reinhold, Middelberg, Rita P. S., Carroll, Robert J., Penninx, Brenda W., Gorski, Mathias, Nalls, Michael, Scott, Rodney J., Katz, Ronit, Sedaghat, Sanaz, Wild, Sarah H., Kardia, Sharon L. R., Ulivi, Sheila, Hwang, Shih-Jen, Enroth, Stefan, Kloiber, Stefan, Trompet, Stella, Feitosa, Mary F., Stengel, Benedicte, Hancock, Stephen J., Turner, Stephen T., Rosas, Sylvia E., Stracke, Sylvia, Harris, Tamara B., Zeller, Tanja, Zemunik, Tatijana, Lehtimäki, Terho, Illig, Thomas, Isaacs, Aaron, Aspelund, Thor, Nikopensius, Tiit, Esko, Tonu, Tanaka, Toshiko, Gyllensten, Ulf, Völker, Uwe, Emilsson, Valur, Vitart, Veronique, Aalto, Ville, Gudnason, Vilmundur, Dehghan, Abbas, Chouraki, Vincent, Chen, Wei-Min, Igl, Wilmar, März, Winfried, Koenig, Wolfgang, Lieb, Wolfgang, Loos, Ruth J. F., Liu, Yongmei, Snieder, Harold, Pramstaller, Peter P., d'Adamo, Pio, Parsa, Afshin, O'Connell, Jeffrey R., Susztak, Katalin, Hamet, Pavel, Tremblay, Johanne, de Boer, Ian H., Böger, Carsten A., Goessling, Wolfram, Chasman, Daniel I., Köttgen, Anna, Adeyemo, Adebowale, Kao, W. H. Linda, Fox, Caroline S., ICBP Consortium, AGEN Consortium, CARDIOGRAM, CHARGe-Heart Failure Group, ECHOGen Consortium, Dieffenbach, Aida Karina, Zonderman, Alan B., Nolte, Ilja M., van der Most, Peter J., Chu, Audrey Y., Wright, Alan F., Shuldiner, Alan R., Morrison, Alanna C., Hofman, Albert, Smith, Albert V., Dreisbach, Albert W., Franke, Andre, Uitterlinden, Andre G., Metspalu, Andres, Tonjes, Anke, Li, Man, Lupo, Antonio, Robino, Antonietta, Johansson, Åsa, Demirkan, Ayse, Kollerits, Barbara, Freedman, Barry I., Ponte, Belen, Oostra, Ben A., Paulweber, Bernhard, Kräemer, Bernhard K., Mijatovic, Vladan, Mitchell, Braxton D., Buckley, Brendan M., Peralta, Carmen A., Hayward, Caroline, Helmer, Catherine, Rotimi, Charles N., Shaffer, Christian M., Müeller, Christian, Sala, Cinzia, van Duijn, Cornelia M., Garnaas, Maija, Saint-Pierre, Aude, Ackermann, Daniel, Shriner, Daniel, Ruggiero, Daniela, Toniolo, Daniela, Lu, Yingchang, Cusi, Daniele, Czamara, Darina, Ellinghaus, David, Siscovick, David S., Tin, Adrienne, Ruderfer, Douglas, Gieger, Christian, Grallert, Harald, Rochtchina, Elena, Atkinson, Elizabeth J., Holliday, Elizabeth G., Boerwinkle, Eric, Salvi, Erika, Bottinger, Erwin P., Murgia, Federico, Sorice, Rossella, Rivadeneira, Fernando, Ernst, Florian, Kronenberg, Florian, Hu, Frank B., Navis, Gerjan J., Curhan, Gary C., Ehret, George B., Homuth, Georg, Coassin, Stefan, Thun, Gian-Andri, Li, Yong, Pistis, Giorgio, Gambaro, Giovanni, Malerba, Giovanni, Montgomery, Grant W., Eiriksdottir, Gudny, Jacobs, Gunnar, Li, Guo, Wichmann, H-Erich, Campbell, Harry, Schmidt, Helena

Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

- McLaughlin, Russell L., Schijven, Dick, Schall, Ulrich, Scott, Rodney J., van Rheenen, Wouter, van Eijk, Kristel R., O'Brien, Margaret, Project MinE GWAS Consortium,, Schizophrenia Working Group of the Psychiatric Genomics Consortium,, Henskens, Frans A., Loughland, Carmel M., Michie, Patricia T., Khan, René S., Ophoff, Roel A., Goris, An, Bradley, Daniel G., Al-Chalabi, Ammar, van den Berg, Leonard H., Luykx, Jurjen J.

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

- Franceschini, Nora, Giambartolomei, Claudia, Kavousi, Maryam, Dale, Caroline, Smith, Albert V., Hofer, Edith, van Leeuwen, Elisabeth M., Nolte, Ilija M., Lu, Lingyi, Scholz, Markus, Sargurupremraj, Muralidharan, Pitkänen, Niina, de Vries, Paul S., Franzén, Oscar, Holliday, Elizabeth G., Finan, Chris, Huntley, Rachael P., Lovering, Ruth C., Tajuddin, Salman M., Winkler, Thomas W., Graff, Misa

Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

- Couch, Fergus J., Kuchenbaecker, Karoline B., Aittomäki, Kristiina, Ambrosone, Christine, Andrulis, Irene L., Anton-Culver, Hoda, Arndt, Volker, Arun, Banu K., Arver, Brita, Barile, Monica, Barkardottir, Rosa B., Barrowdale, Daniel, Michailidou, Kyriaki, Scott, Rodney, Mendoza-Fandino, Gustavo A., Nord, Siljie, Lilyquist, Janna, Olswold, Curtis, Hallberg, Emily, Agata, Simona, Ahsan, Habibul

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness

- Willems, Sara M., Wright, Daniel J., Thalamuthu, Anbupalam, Mangino, Massimo, Liu, Jun, Demirkan, Ayse, Lek, Monkol, Xu, Liwen, Wang, Guan, Oldmeadow, Christopher, Gaulton, Kyle J., Lotta, Luca A., Day, Felix R., Attia, John R., Trajanoska, Katerina, Joshi, Peter K., Morris, John A., Matteini, Amy M., Garton, Fleur C., Grarup, Niels, Oskolkov, Nikolay

LncRNA REG1CP promotes tumorigenesis through an enhancer complex to recruit FANCJ helicase for REG3A transcription

- Yari, Hamed, Jin, Lei, Teng, Liu, Wang, Yufang, Wu, Yongyan, Liu, Guang Zhi, Gao, Wei, Liang, Jin, Xi, Yanfeng, Feng, Yu Chen, Zhang, Chunming, Zhang, Yuan Yuan, Tabatabaee, Hessam, La, Ting, Yang, Rui Hong, Wang, Fu Hua, Yan, Xu Guang, Farrelly, Margaret, Scott, Rodney, Liu, Tao, Thorne, Rick F., Guo, Su Tang, Zhang, Xu Dong

Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns

- Joubert, Bonnie R., den Dekker, Herman T., Håberg, Siri E., Reese, Sarah E., Peters, Marjolein J., Kulle Andreassen, Bettina, Steegers, Eric A. P., Nilsen, Roy M., Vollset, Stein E., Midttun, Øivind, Ueland, Per M., Franco, Oscar H., Felix, Janine F., Dehghan, Abbas, de Jongste, Johan C., Wu, Michael C., Wang, Tianyuan, Peddada, Shyamal D., Jaddoe, Vincent W. V., Nystad, Wenche, Duijts, Liesbeth, London, Stephanie J., Bohlin, Jon, Ligthart, Symen, Beckett, Emma, Tiemeier, Henning, van Meurs, Joyce B., Uitterlinden, Andre G., Hofman, Albert

Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process

- Springelkamp, Henriët, Höhn, René, Luo, Xiaoyan, Deloukas, Panos, Duncanson, Audrey, Jankowski, Janusz, Markus, Hugh S., Mathew, Christopher G., Palmer, Colin N. A., Plomin, Robert, Rautanen, Anna, Sawcer, Stephen J., Trembath, Richard C., Ramdas, Wishal D., Viswanathan, Ananth C., Wood, Nicholas W., Spencer, Chris C. A., Band, Gavin, Bellenguez, Céline, Freeman, Colin, Hellenthal, Garrett, Giannoulatou, Eleni, Pirinen, Matti, Pearson, Richard, Vithana, Eranga, Strange, Amy, Su, Zhan, Vukcevic, Damjan, Donnelly, Peter, Langford, Cordelia, Hunt, Sarah E., Edkins, Sarah, Gwilliam, Rhian, Blackburn, Hannah, Bumpstead, Suzannah J., Nongpiur, Monisha E., Droniv, Serge, Gillman, Matthew, Gray, Emma, Hammond, Naomi, Jayakumar, Alagurevathi, McCann, Owen T., Liddle, Jennifer, Potter, Simon C., Ravindrarajah, Alagurevathi, Rocketts, Michelle, Montgomery, Grant W., Waller, Matthew, Weston, Paul, Widaa, Sara, Whittaker, Pamela, Barroso, Ines, Blackwell, Jenefer M., Brown , Matthew A., Corvin, Aiden, Xu, Liang, Spencer , Chris C. A., Spector, Timothy D., Mirshahi, Alireza, Saw, Seang-Mei, Vingerling, Johannes R., Teo, Yik-Ying, Haines, Jonathan L., Wolfs, Roger C. W., Lemij, Hans G., Tai, E-Shyong, Mountain, Jenny E., Jansonius, Nomdo M., Jonas, Jost B., Hammond, CJ, Gharahkhani, Puya, Lu, Yi, Amin, Najaf, Mishra, Aniket, Karssen, Lennart C., Sim, Kar-seng, van Leeuwen, Elisabeth M., Iglesias, Adriana I., Verhoeven, Virginie J. M., Hauser, Michael A., Loon, Seng-Chee, Despriet, Dominiek D. G., Nag, Abhishek, Venturini, Cristina, Hysi, Pirro G., Sanfilippo, Paul G., Schillert, Arne, Kang, Jae H., Landers, John, Jonasson, Fridbert, Cree, Angela J., van Koolwijk, Leonieke M. E., Rivadeneira, Fernando, Souzeau, Emmanuelle, Jonsson, Vesteinn, Khor, Chiea-Cheun, Menon, Geeta, Mitchell, Paul, Wang, Jie Jin, Rochtchina, Elena, Attia, John, Scott, Rodney, Holliday, Elizabeth G., Wong, Tien-Yin, Baird, Paul N., Xie, Jing, Loomis, Stephanie J., Inouye, Michael, Viswanathan, Ananth, Sim, Xueling, Weinreb, Robert N., de Jong, Paulus T. V. M., Oostra, Ben A., Uitterlinden, André G., Hofman, Albert, Ennis, Sarah, Thorsteinsdottir, Unnu, Bailey, Jessica N. Cooke, Burdon, Kathryn, Allingham, R. Band, Brilliant, Murray H., Budenz, Donald L., Christen, William G., Fingert, John, Friedman, David S., Gaasterland, Douglas, Gaasterland, Terry, Gibson, Jane, Hauder, Michael A., Kang, Jae Hee, Kraft, Peter, Lee, Richard K., Lichter, Paul R., Liu, Yutao, Moroi, Sayoko E., Pasquale, Louis R., Thorleifsson, Gudmar, Pericak-Vance, Margaret A., Realini, Anthony, Richards, Julia E., Schuman, Joel S., Scott, William K., Singh, Kuldev, Sit, Arthur J., Vollrath, Douglas, Wiggs, Janey L., Janssen, Sarah F., Wollstein, Gadi, Zack, Donald J., Zhang, Kang, Bramon, Elvira, Brown, Matthew A., Casas, Juan P.

Methylome sequencing in triple-negative breast cancer reveals distinct methylation clusters with prognostic value

- Stirzaker, Clare, Zotenko, Elena, Avery-Kiejda, Kelly A., Peters, Kate M., French, Juliet D., Stein, Sandra, Korbie, Darren J., Trau, Matt, Forbes, John F., Scott, Rodney J., Brown, Melissa A., Francis, Glenn D., Song, Jenny Z., Clark, Susan J., Qu, Wenjia, Nair, Shalima S., Locke, Warwick J., Stone, Andrew, Armstong, Nicole J., Robinson, Mark D., Dobrovic, Alexander

Mismatch between marine plankton range movements and the velocity of climate change

- Chivers, William J., Walne, Anthony W., Hays, Graeme C.

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

- Wyss, Annah B., Sofer, Tamar, Gao, Wei, Ahluwalia, Tarunveer S., Tang, Wenbo, Oldmeadow, Christopher, Duan, Qing, de Jong, Kim, Wojczynski, Mary K., Wang, Xin-Qun, Noordam, Raymond, Hartwig, Fernando Pires, Lee, Mi Kyeong, Holliday, Elizabeth G., McEvoy, Mark, Attia, John R., Terzikhan, Natalie, Nguyen, Jennifer N., Lahousse, Lies, Latourelle, Jeanne C., Smith, Albert Vernon, Bartz, Traci M., Feitosa, Mary F.

Non-canonical function of spindle assembly checkpoint proteins after APC activation reduces aneuploidy in mouse oocytes

- Lane, Simon I. R., Jones, Keith T.

North Atlantic storm track changes during the Last Glacial Maximum recorded by alpine speleothems

- Luetscher, Marc, Boch, R., Sodeman, H., Spötl, C., Cheng, H., Edwards, R. L., Frisia, S., Hof, F., Muller, W.