No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis

- Goris, An, van Setten, Jessica, Diekstra, Frank, Ripke, Stephan, Patsopoulos, Nikolaos A., Sawcer, Stephen J., The International Multiple Sclerosis Genetics Consortium, van Es, Michael, The Australia and New Zealand MS Genetics Consortium, Andersen, Peter M., Melki, Judith, Meininger, Vincent, Hardiman, Orla, Landers, John E., Brown, Robert H., Shatunov, Aleksey, Leigh, Nigel, Al-Chalabi, Ammar, Shaw, Christopher E., Traynor, Bryan J., Chio, Adriano, Restagno, Gabriella, Mora, Gabriele, Ophoff, Roel A., Oksenberg, Jorge R., Van Damme, Philip, Compston, Alastair, Robberecht, Wim, Dubois, Bénédicte, van den Berg, Leonard H., De Jager, Philip L., Veldink, Jan H., de Bakker, Paul I. W.

A rare P2X7 variant Arg307Gln with absent pore formation function protects against neuroinflammation in multiple sclerosis

- Gu, Ben J., Field, Judith, Butzkueven, Helmut, Gresle, Melissa, Laws, Simon M., Petrou, Steven, Hoffjan, Sabine, Akkad, Denis A., Graham, Colin A., Hawkins, Stanley, Glaser, Anna, Bedri, Sahl Khalid, Dutertre, Sébastien, Hillert, Jan, Matute, Carlos, Antiguedad, Alfredo, Wiley, James S., Ou, Amber, Kilpatrick, Trevor J., Lechner-Scott, Jeannette, Scott, Rodney, Lea, Rodney, Taylor, Bruce V., Stankovich, Jim

Altered LKB1/AMPK/TSC1/TSC2/mTOR signaling causes disruption of sertoli cell polarity and spermatogenesis

- Tanwar, Pradeep S., Kaneko-Tarui, Tomoko, Zhang, LiHua, Teixeira, Jose M.

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium

- Moayyeri, Alireza, Hsu, Yi-Hsiang, Smith, Albert V., Cooper, Cyrus, Kung, Annie Wai Chee, Lips, Paul, Alen, Markku, Attia, John, Luisa Brandi, Maria, de Groot, Lisette C. P. G. M., Lehtimäeki, Terho, Riancho, José A., Campbell, Harry, Pye, Stephen R., Liu, Yongmei, Harris, Tamara B., Akesson, Kristina, Karlsson, Magnus, Lee, Jong-Young, Wallaschofski, Henri, Duncan, Emma L., O'Neill, Terence W., Gudnason, Vilmundur, Spector, Timothy D., Leo, Paul J., Rousseau, François, Orwoll, Eric, Cummings, Steven R., Wareham, Nick J., Rivadeneira, Fernando, Uitterlinden, Andre G., Prince, Richard L., Kiel, Douglas P., Reeve, Jonathan, Kaptoge, Stephen K., Teumer, Alexander, Hwang, Joo-Yeon, Ohlsson, Claes, McGuigan, Fiona, Minster, Ryan L., Hayward, Caroline, Olmos, José M., Karasik, David, Lyytikäeinen, Leo-Pekka, Lewis, Joshua R., Swart, Karin M. A., Masi, Laura, Oldmeadow, Chris, Holliday, Elizabeth G., Cheng, Sulin, van Schoor, Natasja M., Harvey, Nicholas C., Kruk, Marcin, Estrada, Karol, del Greco M, Fabiola, Igl, Wilmar, Trummer, Olivia, Grigoriou, Efi, Luben, Robert, Liu, Ching-Ti, Zhou, Yanhua, Oei, Ling, Medina-Gomez, Carolina, Zmuda, Joseph, Xiao, Su-Mei, Tranah, Greg, Brown, Suzanne J., Williams, Frances M., Soranzo, Nicole, Jakobsdottir, Jphanna, Siggeirsdottir, Kristin, Holliday, Kate L., Hannemann, Anke, Go, Min Jin, Garcia, Melissa, Nielson, Carrie, Polasek, Ozren, Laaksonen, Marika, Zhu, Kun, Enneman, Anke W., McEvoy, Mark, Peel, Roseanne, Sham, Pak Chung, Jaworski, Maciej, Johansson, Åsa, Hicks, Andrew A., Srikanth, Priya, Pludowski, Pawel, Scott, Rodney, Dhonukshe-Rutten, Rosalie A. M., van der Velde, Nathalie, Käehöenen, Mika, Viikari, Jorma S., Sieväenen, Harri, Raitakari, Olli T., González-Macías, Jesús, Hernández, Jose L., Giroux, Sylvie, Mellströem, Dan, Ljunggren, Östen, Cho, Yoon Shin, Vöelker, Uwe, Nauck, Matthias, Homuth, Georg, Vöelzke, Henry, Haring, Robin, Brown, Matthew A., McCloskey, Eugene, Wilson, Scott G., Nicholson, Geoffrey C., Eastell, Richard, Eisman, John A., Jones, Graeme, Reid, Ian R., Dennison, Elaine M., Wark, John, Boonen, Steven, Vanderschueren, Dirk, Wu, Frederick C. W., Zheng, Hou-Feng, Aspelund, Thor, Richards, J. Brent, Bauer, Doug, Hofman, Albert, Khaw, Kay-Tee, Dedoussis, George, Obermayer-Pietsch, Barbara, Gyllensten, Ulf, Pramstaller, Peter P., Lorenc, Roman S.

Resequencing and fine-mapping of the chromosome 12q13-14 locus associated with multiple sclerosis refines the number of implicated genes

- Cortes, Adrian, Field, Judith, Glazov, Evgeny A., Hadler, Johanna, ANZgene Consortium,, Stankovich, Jim, Brown, Matthew A., Lechner-Scott, Jeannette, Moscato, Pablo

GWAS meta-analysis of 16 852 women identifies new susceptibility locus for endometrial cancer

- Chen, Maxine M., O'Mara, Tracy A., Cheng, Timothy H. T., Cook, Linda S., Crous-Bou, Marta, Doherty, Jennifer, Friedenreich, Christine M., Garcia-Closas, Montserrat, Gaudet, Mia M., Gorman, Maggie, Haiman, Christopher, Hankinson, Susan E., Thompson, Deborah J., Holliday, Elizabeth G., Painter, Jodie N., Australian National Endometrial Cancer Study Group (ANECS),, Attia, John, Black, Amanda, Brinton, Louise, Chanock, Stephen, Chen, Chu

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

- de Vries, P. S., Chasman, D. I., Hottenga, J. J., Trompet, S, Müller-Nurasyid, M., Zhao, J. H., Brody, J. A., Kleber, M. E., Guo, X., Wang, J. J., Auer, P. L., Attia, John R., Sabater-Lleal, M., Yanek, L. R., Ahluwalia, T. S., Lahti, J., Venturini, C., Tanaka, T., Bielak, L. F., Joshi, P. K., Rocanin-Arjo, A., Kolcic, I., Navarro, P., Chen, M. H., Rose, L. M., Oldmeadow, Christopher, Riess, H., Mazur, J., Basu, S., Goel, A., Yang, Q., Ghanbari, M., Gonneke, Willemsen, Rumley, A., Huffman, J. E., Fiorillo, E., de Craen, A. J. M., Grotevendt, A., Scott, R., Taylor, K. D., Delgado, G. E., Yao, J., Kifley, A., Kooperberg, C., Qayyum, R., Steri, M., Lopez, L., Berentzen, T. L., Räikkönen, K., Mangino, M., Bandinelli, S., Peyser, P. A., Wild, S., Trégouët, D. A., Wright, A. F., Marten, J., Tang, W., Zemunik, T., Morrison, A. C., Sennblad, B., Tofler, G., de Maat, M. P. M., De Geus, E. J. C., Lowe, G. D., Zoledziewska, M., Sattar, N., Binder, H., Teumer, A., Völker, U., Waldenberger, M., Khaw, K. T., Scott, Rodney J., Marioni, R. E., Grossmann, V.

SIAH1 targets the alternative splicing factor T-STAR for degradation by the proteasome

- Venables, Julian P., Dalgliesh, Caroline, Paronetto, Maria Paolo, Skitt, Lindi, Thornton, Jared K., Saunders, Philippa T., Sette, Claudio, Jones, Keith T., Elliott, David J.

Dysregulation of miRNA 181b in the temporal cortex in schizophrenia

- Beveridge, Natalie J., Tooney, Paul A., Carroll, Adam P., Gardiner, Erin, Bowden, Nikola A., Scott, Rodney J., Tran, Nham, Dedova, Irina, Cairns, Murray J.

Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade

- Purrington, Kristen S., Slettedahl, Seth, Carpenter, Jane, Ko, Yon-Dschun, Van Deurzen, Carolien H. M., Martens, John W. M., Kriege, Mieke, Figueroa, Jonine D., Chanock, Stephen J., Lissowska, Jolanta, Tomlinson, Ian, Kerin, Michael J., Miller, Nicola, Yannoukakos, Drakoulis, Schneeweiss, Andreas, Tapper, William J., Gerty, Susan M., Durcan, Lorraine, Mclean, Catriona, Milne, Roger L., Baglietto, Laura, dos Santos Silva, Isabel, Fletcher, Olivia, Johnson, Nichola, Haiman, Christopher A., Van'T Veer, Laura J., Cornelissen, Sten, Försti, Ast, Torres, Diana, Rüdiger, Thomas, Rudolph, Anja, Flesch-Janys, Dieter, Nickels, Stefan, Weltens, Caroline, Floris, Giuseppe, Fasching, Peter A., Moisse, Matthieu, Dennis, Joe, Wang, Qin, Dunning, Alison M., Shah, Mitul, Brown, Judith, Simard, Jacques, Anton-Culver, Hoda, Neuhausen, Susan L., Hopper, John L., Mannermaa, Arto, Bogdanova, Natalia, Dörk, Thilo, Zheng, Wei, Radice, Paolo, Jakubowska, Anna, Lubinski, Jan, Devillee, Peter, Brauch, Hiltrud, Hooning, Maartje, García-Closas, Montserrat, Winqvist, Robert, Sawyer, Elinor, Burwinkel, Barbara, Marmee, Frederick, Eccles, Diana M., Giles, Graham G., Peto, Julian, Schmidt, Marjanka, Broeks, Annegien, Hamann, Ute, Chang-Claude, Jenny, Brenner, Hermann, Lambrechts, Diether, Pharoah, Paul D. P., Easton, Douglas, Pankratz, V. Shane, Slager, Susan, Vachon, Celine M., Couch, Fergus J., Lindblom, Annika, Chenevix-Trench, Georgia, Benitez, Javier, Bolla, Manjeet K., Swerdlow, Anthony, Kristensen, Vessela, Guénel, Pascal, Meindl, Alfons, Darabi, Hatef, Eriksson, Michael, Fagerholm, Rainer, Aittomäki, Kristiina, Blomqvist, Carl, Nordestgaard, Børge G., Michailidou, Kyriaki, Nielsen, Sune F., Flyger, Henrik, Wang, Xianshu, Olswold, Curtis, Olson, Janet E., Mulligan, Anna Marie, Knight, Julia A., Tchatchou, Sandrine, Reed, Malcolm W. R., Cross, Simon S., Czene, Kamila, Liu, Jianjun, Li, Jingmei, Humphreys, Keith, Clarke, Christine, Scott, Rodney, ABCTB Investigators, Fostira, Florentia, Fountzilas, George, Konstantopoulou, Irene, Henderson, Brian E., Nevanlinna, Heli, Schumacher, Frederick, Le Marchand, Loic, Ekici, Arif B., Hartmann, Arndt, Beckmann, Matthias W., Hartikainen, Jaana M., Kosma, Veli-Matti, Kataja, Vesa, Jukkola-Vuarinen, Arja, Pylkäs, Katri, Bojesen, Stig E., Kauppila, Saila, Dieffenbach, Aida Karina, Stegmaier, Christa, Arndt, Volker, Margolin, Sara, Australian Ovarian Cancer Study Group, kConFab Investigators, Balleine, Rosemary, Perez, Jose Ignacio Arias, Zamora, M. Pilar, Andrulis, Irene L., Menéndez, Primitiva, Ashworth, Alan, Jones, Michael, Orr, Nick, Arveux, Patrick, Kerbrat, Pierre, Truong, Thérèse, Bugert, Peter, Toland, Amanda E., Ambrosone, Christine B., Cox, Angela, Labrèche, France, Goldberg, Mark S., Dumont, Martine, Ziogas, Argyrios, Lee, Eunjung, Dite, Gillian S., Apicella, Carmel, Southey, Melissa C., Long, Jirong, Shrubsole, Martha, Hall, Per, Deming-Halverson, Sandra, Ficarazzi, Fiolmena, Barile, Monica, Peterlongo, Paolo, Durda, Katarzyna, Jaworska-Bieniek, Katarzyna, Tollenaar, Robert A. E. M., Seynaeve, Caroline, The GENICA Network, Brüning, Thomas

The CYP27B1 variant associated with an increased risk of autoimmune disease is underexpressed in tolerizing dendritic cells

- Shahijanian, Fernando, Parnell, Grant P., Baxter, Alan, Kermode, Allan, Carroll, William, Butzkueven, Helmut, Booth, David, Stewart, Graeme, Vucic, Steve, Wiley, James, Field, Judith, Tajouri, Lotti, McKay, Fiona C., Griffiths, Lyn, Barnett, Michael, Scott, Rodney, Lechner-Scott, Jeannette, Moscato, Pablo, Broadley, Simon, Slee, Mark, Kilpatrick, Trevor, Taylor, Bruce, Charlesworth, Jac, Gatt, Prudence N., Brown, Matt, Mason, Deborah, Stewart, Graeme J., Booth, David R., Shojoei, Maryam, O'Connor, Kate S., Schibeci, Stephen D., Brilot, Fabienne, Liddle, Christopher, Batten, Marcel

Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk.

- Painter, Jodie N., O'Mara, Tracy A., Healey, Catherine S., Fridley, Brooke L., Børresen-Dale, Anne-Lise, Kristensen, Vessela N., Cox, Angela, Swerdlow, Anthony J., Orr, Nicholas, Bolla, Manjeet K., Wang, Qin, Palmieri Weber, Rachel, Chen, Zhihua, Kaufmann, Susanne, Shah, Mitul, French, Juliet D., Pharoah, Paul D. P., Dunning, Alison M., Tomlinson, Ian, Easton, Douglas F., Edwards, Stacey L., Thompson, Deborah J., Spurdle, Amanda B., Hillman, Kristine M., Walpole, Carina, Moya, Leire, Pollock, Pamela, Jones, Angela, Howarth, Kimberley, Martin, Lynn, Gorman, Maggie, Batra, Jyotsna, Hodgson, Shirley, National Study of Endometrial Cancer Genetics Group (NSECG), CHIBCHA Consortium, De Polanco, Ma. Magdalena Echeverry, Sans, Monica, Carracedo, Angel, Castellvi-Bel, Sergi, Rojas-Martinez, Augusto, Santos, Erika, Teixeira, Manuel R., Cheng, Timothy, Carvajal-Carmona, Luis, Shu, Xiao-Ou, Long, Jirong, Zheng, Wei, Xiang, Yong-Bing, The Australian National Endometrial Cancer Study Group (ANECS), Montgomery, Grant W., Webb, Penelope M., Scott, Rodney J., McEvoy, Mark, Lose, Felicity A., Attia, John, Holliday, Elizabeth, Martin, Nicholas G., Nyholt, Dale R., Henders, Anjali K., Fasching, Peter A., Hein, Alexander, Beckmann, Matthias W., Renner, Stefan P., Dörk, Thilo, Dennis, Joe, Hillemanns, Peter, Dürst, Matthias, Runnebaum, Ingo, Lambrechts, Diether, Coenegrachts, Lieve, Schrauwen, Stefanie, Amant, Frederic, Winterhoff, Boris, Dowdy, Sean C., Goode, Ellen L., Michailidou, Kyriaki, Teoman, Attila, Salvesen, Helga B., Trovik, Jone, Njolstad, Tormund S., Werner, Henrica M. J., Ashton, Katie, Proietto, Tony, Otton, Geoffrey, Tzortzatos, Gerasimos, Mints, Miriam, Tyrer, Jonathan P., Tham, Emma, RENDOCAS, Hall, Per, Czene, Kamila, Liu, Jianjun, Li, Jingmei, Hopper, John L., Southey, Melissa C., Australian Ovarian Cancer Study (AOCS), Ekici, Arif B., Ahmed, Shahana, Ruebner, Matthias, Johnson, Nicola, Peto, Julian, Burwinkel, Barbara, Marme, Frederik, Brenner, Hermann, Dieffenbach, Aida K., Miendl, Alfons, Brauch, Hiltrud, The GENICA Network,, Ferguson, Kaltin, Lindblom, Annika, Depreeuw, Jeroen, Moisse, Matthieu, Chang-Claude, Jenny, Rudolph, Anja, Couch, Fergus J., Olsen, Janet E., Giles, Graham G., Bruinsma, Fiona, Cunnigham, Julie M.

Recognizable cerebellar dysplasia associated with mutations in multiple tubulin genes

- Oegema, Renske, Cushion, Thomas D., Dobyns, William B., Ishak, Gisele E., Rees, Mark I., Doherty, Dan, Phelps, Ian G., Chung, Seo-Kyung, Dempsey, Jennifer C., Collins, Sarah, Mullins, Jonathan G. L., Dudding, Tracy, Gill, Harinder, Green, Andrew J.

Systematic review and meta-analysis of the association between complementary factor HY402H polymorphisms and age-related macular degeneration

- Thakkinstian, Ammarin, Han, Pearline, McEvoy, Mark, Smith, Wayne, Hoh, Josephine, Magnusson, Kristinn, Zhang, Kang, Attia, John

The multiple sclerosis whole blood mRNA transcriptome and genetic associations indicate dysregulation of specific T cell pathways in pathogenesis

- Gandhi, Kaushal S., McKay, Fiona C., Danoy, Patrick, Stewart, Graeme J., Broadley, Simon, Moscato, Pablo, Lechner-Scott, Jeannette, Scott, Rodney J., Booth, David R., ANZgene Multiple Sclerosis Genetics Consortium, Cox, Mathew, Riveros, Carlos, Armstrong, Nicola, Heard, Robert N., Vucic, Steve, Williams, David W., Stankovich, Jim, Brown, Matthhew

Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks

- Kerzendorfer, Claudia, Whibley, Annabel, Carpenter, Gillian, Outwin, Emily, Chiang, Shih-Chieh, Turner, Gillian, Schwartz, Charles, El-Khamisy, Sherif, Raymond, F. Lucy, O'Driscoll, Mark

Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis

- Lee, S. Hong, Harold, Denise, Nyholt, Dale R., Goddard, Michael E., Zondervan, Krina T., Williams, Julie, Montgomery, Grant W., Wray, Naomi R., Visscher, Peter M.

Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk

- Pouget, Jennie G., Schizophrenia Working Group of the Psychiatric Genomics Consortium,, Martin, Javier, Mayes, Maureen D., Bossini-Castillo, Lara, López-Isac, Elena, Jin, Ying, Santorico, Stephanie A., Spritz, Richard A., Hakonarson, Hakon, Polychronakos, Constantin, Raychaudhuri, Soumya, Han, Buhm, Knight, Jo, Cairns, Murray, Henskens, Frans A., Kelly, Brian J., Loughland, Carrmel M., Michie, Patricia T., Schall, Ulrich A., Scott, Rodney, Tooney, Paul A., Wu, Yang, Mignot, Emmanuel, Ollila, Hanna M., Barker, Jonathan, Spain, Sarah, Dand, Nick, Trembath, Richard

Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero

- Warrington, Nicole M., Shevroja, Enisa, Hemani, Gibran, Hysi, Pirro G., Jiang, Yunxuan, Auton, Adam, Boer, Cindy G., Mangino, Massimo, Wang, Carol A., Kemp, John P., McMahon, George, Medina-Gomez, Carolina, Hickey, Martha, Trajanoska, Katerina, Wolke, Dieter, Ikram, M. Arfan, The 23and Me Research Team, Montgomery, Grant W., Felix, Janine F., Wright, Margaret J., Pennell, Craig E.