A Novel Model Using AAV9-Cre to Knockout Adult Leydig Cell Gene Expression Reveals a Physiological Role of Glucocorticoid Receptor Signalling in Leydig Cell Function
Ablation of glucocorticoid receptor in the hindbrain of the mouse provides a novel model to investigate stress disorders
- Gannon, Anne-Louise, O'Hara, Laura, Mitchell, Rod T., Smith, Lee B., Mason, J. Ian, Rebourcet, Diane, Smith, Sarah, Traveres, Adriana, Alcaide-Corral, Carlos Jose, Frederiksen, Hanne, Jorgensen, Anne, Milne, Laura
Androgen receptor is dispensable for x-zone regression in the female adrenal but regulates post-partum corticosterone levels and protects cortex integrity
Androgen receptor signalling in the male adrenal facilitates X-zone regression, cell turnover and protects against adrenal degeneration during ageing
Leukemia inhibitory factor-receptor is dispensable for prenatal testis development but is required in sertoli cells for normal spermatogenesis in mice
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