Randomised controlled trial for the titration of oral corticosteroids using markers of inflammation in severe asthma

- Ramsahai, J. Michael, Simpson, Jodie L., Cook, Alistair, Gibson, Peter G., McDonald, Vanessa, Grainge, Christopher, Heaney, Liam G., Wark, Peter A. B.

Severity of Lung Function Impairment Drives Transcriptional Phenotypes of COPD and Relates to Immune and Metabolic Processes

- Negewo, Netsanet A., Gibson, Peter G., Simpson, Jodie L., McDonald, Vanessa M., Baines, Katherine J.

An altered sputum macrophage transcriptome contributes to the neutrophilic asthma endotype

- Fricker, Michael, Qin, Ling, Chung, Kian Fan, Gibson, Peter G., Sánchez-Ovando, Stephany, Simpson, Jodie L., Baines, Katherine J., Riveros, Carlos, Scott, Hayley A., Wood, Lisa G., Wark, Peter A. B., Kermani, Nazanin Z.

Early Th2 inflammation in the upper respiratory mucosa as a predictor of severe COVID-19 and modulation by early treatment with inhaled corticosteroids: a mechanistic analysis

- Baker, Jonathan R., Mahdi, Mahdi, Nicolau, Dan V., Ramakrishnan, Sanjay, Barnes, Peter J., Simpson, Jodie L., Cass, Steven P., Russell, Richard E. K., Donnelly, Louise E., Bafadhel, Mona

Patterns of azithromycin use in obstructive airway diseases: a real-world observational study

- Thomas, Dennis, McDonald, Vanessa M., Simpson, Jodie L., Smith, Amber, Gupta, Sachin, Majellano, Eleanor, Gibson, Peter G.

Rothia mucilaginosa is an anti-inflammatory bacterium in the respiratory tract of patients with chronic lung disease

- Rigauts, Charlotte, Aizawa, Juliana, Dondelinger, Yves, Vereecke, Lars, Van Acker, Heleen, Simpson, Jodie L., Burr, Lucy, Willems, Anne, Tunney, Michael M., Cigana, Cristina, Bragonzi, Alessandra, Coenye, Tom, Taylor, Steven L., Crabbé, Aurelie, Rogers, Geraint B., Govaerts, Matthias, Cos, Paul, Ostyn, Lisa, Sims, Sarah, Vandeplassche, Eva, Sze, Mozes

Airway monocyte modulation relates to tumour necrosis factor dysregulation in neutrophilic asthma

- Niessen, Natalie M., Gibson, Peter G., Simpson, Jodie L., Scott, Hayley A., Baines, Katherine J., Fricker, Michael

Differential cell counts using center-point networks achieves human-level accuracy and efficiency over segmentation

- Lee, Sandra M. W., Shaw, Andrew, Simpson, Jodie L., Uminsky, David, Garratt, Luke W.

Endoplasmic reticulum-unfolded protein response signalling is altered in severe eosinophilic and neutrophilic asthma

- Pathinayake, Prabuddha S., Waters, David W., Gibson, Peter G., Hansbro, Philip M., Wark, Peter A. B., Nichol, Kristy S., Brown, Alexandra C., Reid, Andrew T., Hsu, Alan Chen-Yu, Horvat, Jay C., Wood, Lisa G., Baines, Katherine J., Simpson, Jodie L.

Hemopexin: a novel anti-inflammatory marker for distinguishing COPD from asthma

- Winter, Natasha A., Gibson, Peter G., Fricker, Michael, Simpson, Jodie L., Wark, Peter A., McDonald, Vaness M.

Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial

- Ramakrishnan, Sanjay, Nicolau, Dan V., Bright, Stephen, Butler, Christopher, Cane, Jennifer L., Halner, Andreas, Matthews, Philippa C., Donnelly, Louise E., Simpson, Jodie L., Baker, Jonathan R., Fadai, Nabil T., Peterson, Stefan, Langford, Beverly, Bengtsson, Thomas, Barnes, PJ, Russell, REK, Bafadhel, M, Mahdi, Mahdi, Jeffers, Helen, Mwasuku, Christine, Krassowska, Karolina, Fox, Robin, Binnian, Ian, Glover, Victoria

Molecular markers of type 2 airway inflammation are similar between eosinophilic severe asthma and eosinophilic chronic obstructive pulmonary disease

- Fricker, Michael, McDonald, Vanessa M., Winter, Natasha A., Baines, Katherine J., Wark, Peter A. B., Simpson, Jodie L., Gibson, Peter G.

Neutrophil extracellular traps, disease severity, and antibiotic response in bronchiectasis: an international, observational, multicohort study

- Keir, Holly R., Shoemark, Amelia, Cant, Erin, Einarsson, Gisli G., Furrie, Elizabeth, Elborn, J. Stuart, Fong, Christopher J., Finch, Simon, Rogers, Geraint B., Blasi, Francesco, Sibila, Oriol, Aliberti, Stefano, Dicker, Alison J., Simpson, Jodie L., Huang, Jeffrey T. J., Chalmers, James D., Perea, Lidia, Pollock, Jennifer, Giam, Yan Hui, Suarez-Cuartin, Guillermo, Crichton, Megan L., Lonergan, Mike, Oriano, Martina

Neutrophilic asthma features increased airway classical monocytes

- Niessen, Natalie M., Baines, Katherine J., Simpson, Jodie L., Scott, Hayley A., Qin, Ling, Gibson, Peter G., Fricker, Michael

Neutrophils in asthma: The good, the bad and the bacteria

- Crisford, Helena, Sapey, Elizabeth, Rogers, Geraint B., Taylor, Steven, Nagakumar, Prasad, Lokwani, Ravi, Simpson, Jodie L.

Outcomes of protracted bacterial bronchitis in children: A 5-year prospective cohort study

- Ruffles, Tom J.C., Marchant, Julie M., Masters, Ian B., Yerkovich, Stephanie T., Wurzel, Danielle F., Gibson, Peter G., Busch, Greta, Baines, Katherine J., Simpson, Jodie L., Smith-Vaughan, Heidi C., Pizzutto, Susan J., Buntain, Helen M., Hodge, Gregory, Hodge, Sandra, Upham, John W., Chang, Anne B.

Sputum TNF markers are increased in neutrophilic and severe asthma and are reduced by azithromycin treatment

- Niessen, Natalie M., Gibson, Peter G., Peters, Matthew J., Marks, Guy B., Baraket, Melissaa, Simpson, Jodie L., Fricker, Michael, Baines, Katherine J., Barker, Daniel, Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine

The cost-effectiveness of azithromycin in reducing exacerbations in uncontrolled asthma

- O'Neill, Ciaran, Gibson, Peter G., Heaney, Liam G., Upham, John W., Yang, Ian A., Reynolds, Paul N., Hodge, Sandra, Jenkins, Christine R., Peters, Matthew, Marks, Guy B., James, Alan L., Simpson, Jodie L.

The influence of early-life microbial exposures on long-term respiratory health

- Taylor, Steven L., Simpson, Jodie L., Rogers, Geraint B.

Transcriptomics of biopsies identifies novel genes and pathways linked to neutrophilic inflammation in severe asthma

- Sánchez-Ovando, Stephany, Simpson, Jodie L., Barker, Daniel, Baines, Katherine J., Wark, Peter A. B.