ent-Verticilide B1 Inhibits Type 2 Ryanodine Receptor Channels and is Antiarrhythmic in Casq2^-/- Mice^S

- Gochman, Aaron, Do, Tri Q., Cornea, Razvan L., Laver, Derek R., Johnston, Jeffrey N., Knollmann, Bjorn C., Kim, Kyungsoo, Schwarz, Jacob A., Thorpe, Madelaine P., Blackwell, Daniel J., Ritschel, Paxton A., Smith, Abigail N., Rebbeck, Robyn T., Akers, Wendell S.

A bivalent remipede toxin promotes calcium release via ryanodine receptor activation

- Maxwell, Michael J., Thekkedam, Chris, Launikonis, Bradley S., Dulhunty, Angela, Undheim, Eivind A. B., Mobli, Mehdi, Lamboley, Cedric, Chin, Yanni K.-Y., Crawford, Theo, Smith, Jennifer J., Liu, Junyu, Jia, Xinying, Vetter, Irina, Laver, Derek R.

Dantrolene inhibition of ryanodine channels (RyR2) in artificial lipid bilayers depends on FKBP12.6

- Walweel, Kafa, Beard, Nicole, van Helden, Dirk F., Laver, Derek R.

RYR2 channel inhibition is the principal mechanism of flecainide action in CPVT

- Kryshtal, Dmytro O., Blackwell, Daniel J., Egly, Christian L., Smith, Abigail N., Batiste, Suzanne M., Johnston, Jeffrey N., Laver, Derek R., Knollmann, Bjorn C.

Calmodulin inhibition of human RyR2 channels requires phosphorylation of RyR2-S2808 or RyR2-S2814

- Walweel, Kafa, Gomez-Hurtado, Nieves, Laver, Derek R., Rebbeck, Robyn T., Oo, Ye Wint, Beard, Nicole A., Molenaar, Peter, dos Remedios, Chris, van Helden, Dirk F., Cornea, Razvan L., Knollmann, Björn C.

Mammalian TRP on channels are insensitive to membrane stretch

- Nikolaev, Yury A., Cox, Charles D., Ridone, Pietro, Rohde, Paul R., Cordero-Morales, Julio F., Vasquez, Valeria, Laver, Derek R., Martinac, Boris

Secretoneurin is an endogenous calcium/calmodulin-dependent protein kinase II inhibitor that attenuates Ca2+-dependent arrhythmia

- Ottesen, Anett H., Carlson, Catherine R., Lunde, Marianne, Hoff, Jon Erik, Godang, Kristin, Sjaastad, Ivar, Pettilä, Ville, Stridsberg, Mats, Lehnart, Stephan E., Edwards, Andrew G., Lunde, Ida G., Omland, Torbjørn, Eken, Olav Søvik, Stokke, Mathis K., Christensen, Geir, Røsjø, Helge, Louch, William E., Sadredini, Mani, Myhre, Peder L., Shen, Xin, Dalhus, Bjørn, Laver, Derek R., Lunde, Per Kristian, Kurola, Jouni

Regulation of the RyR channel gating by Ca²⁺ and Mg²⁺

- Laver, Derek R.

Cardiac calcium release channel (ryanodine receptor 2) regulation by halogenated anesthetics

- Laver, Derek R., Attia, John, Oldmeadow, Christopher, Quail, Anthony W.

Nerve-induced responses of mouse vaginal smooth muscle

- van Helden, Dirk F., Kamiya, Ayumi, Kelsey, Sam, Laver, Derek R., Jobling, Phillip, Mitsui, Retsu, Hashitani, Hikaru

The emerging role of calmodulin regulation of RyR2 in controlling heart rhythm, the progression of heart failure and the antiarrhythmic action of dantrolene

- Walweel, Kafa, Oo, Ye Win, Laver, Derek R.

A parallel modelling algorithm for simulating calcium release in cells

- Stoddard, Jeremy G., Welsh, James S., Laver, Derek R.

Essential role of calmodulin in RyR inhibition by dantrolene

- Oo, Ye Win, Gomez-Hurtado, Nieves, Walweel, Kafa, van Helden, Dirk F., Imtiaz, Mohammad S., Knollmann, Bjorn C., Laver, Derek R.

Polarized and persistent Ca²⁺ plumes define loci for formation of wall ingrowth papillae in transfer cells

- Zhang, Hui-Ming, Imtiaz, Mohammad S., Laver, Derek R., McCurdy, David W., Offler, Christina E., van Helden, Dirk F., Patrick, John W.

Single mechanically-gated cation channel currents can trigger action potentials in neocortical and hippocampal pyramidal neurons

- Nikolaev, Yury A., Dosen, Peter J., Laver, Derek R., van Helden, Dirk F., Hamill, Owen P.

Differences in the regulation of RyR2 from human, sheep, and rat by Ca²⁺ and Mg²⁺ in the cytoplasm and in the lumen of the sarcoplasmic reticulum

- Walweel, Kafa, Li, Jiao, Molenaar, Peter, Imtiaz, Mohammad S., Quail, Anthony, dos Remedios, Chris G., Beard, Nicole A., Dulhunty, Angela F., van Helden, Dirk F., Laver, Derek R.

Pharmacological approaches that slow lymphatic flow as a snakebite first aid

- van Helden, Dirk F., Thomas, Paul A., Dosen, Peter J., Imtiaz, Mohammad S., Laver, Derek R., Isbister, Geoffrey K.

Beta-adrenergic stimulation increases RyR2 activity via intracellular Ca²⁺ and Mg²⁺ regulation

- Li, Jiao, Imtiaz, Mohammad S., Beard, Nicole A., Dulhunty, Angela F., Thorn, Rick, van Helden Dirk F., Laver, Derek R.

Extraction of sub-microscopic Ca fluxes from blurred and noisy fluorescent indicator images with a detailed model fitting approach

- Kong, Cherrie H. T., Laver, Derek R., Cannell, Mark B.

Selective modulation of different GABA_A receptor isoforms by diazepam and etomidate in hippocampal neurons

- Seymour, Victoria A. L., Curmi, John P., Howitt, Susan M., Casarotto, Marco G., Laver, Derek R., Tierney, M. Louise