A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis

- Beckett, Emma L., Stevens, Richard L., Oliver, Brian G., van Rooijen, Nico, Inman, Mark D., Adachi, Roberto, Soberman, Roy J., Hamadi, Sahar, Wark, Peter A., Foster, Paul S., Hansbro, Philip M., Jarnicki, Andrew G., Kim, Richard Y., Hanish, Irwan, Hansbro, Nicole G., Deane, Andrew, Keely, Simon, Horvat, Jay C., Yang, Ming

Abnormal M1/M2 macrophage phenotype profiles in the small airway wall and lumen in smokers and chronic obstructive pulmonary disease (COPD)

- Eapen, Mathew Suji, Hansbro, Philip M., McAlinden, Kielan, Kim, Richard Y., Ward, Chris, Hackett, Tillie-Louise, Walters, Eugene H., Sohal, Sukhwinder Singh

Airway and parenchymal transcriptomics in a novel model of asthma and COPD overlap

- Tu, Xiaofan, Kim, Richard Y., Loering, Svenja, Nguyen, Duc H., Nair, Prema Mono, Haw, Tatt Jhong, Alemao, Charlotte A., Faiz, Alen, Tay, Hock L., Wark, Peter A. B., Knight, Darryl A., Foster, Paul S., Brown, Alexandra C., Bosco, Anthony, Horvat, Jay C., Hansbro, Philip M., Donovan, Chantal, de Jong, Emma, Jones-Freeman, Bernadette, Ali, Md Khadem, Gomez, Henry M., Budden, Kurtis F., Starkey, Malcolm R., Cameron, Guy J. M.

Asthma-COPD overlap: current understanding and the utility of experimental models

- Tu, Xiaofan, Donovan, Chantal, Kim, Richard Y., Wark, Peter A. B., Horyat, Jay C., Hansbro, Philip M.

Cellular mechanisms underlying steroid-resistant asthma

- Wadhwa, Ridhima, Dua, Kamal, Adcock, Ian M., Horvat, Jay C., Kim, Richard Y., Hansbro, Philip M.

Chlamydia muridarum lung infection in infants alters hematopoietic cells to promote allergic airway disease in mice

- Starkey, Malcolm R., Kim, Richard Y., Horvat, Jay C., Hansbro, Philip M., Idzco, Marco, Beckett, Emma L., Schilter, Heidi C., Shim, Doris, Essilfie, Ama-Tawiah, Nguyen, Duc H., Beagley, Kenneth W., Joerg, Mattes, Mackay, Charles R.

Chlamydial respiratory infection during allergen sensitization drives neutrophilic allergic airways disease

- Horvat, Jay C., Starkey, Malcolm R., Kim, Richard Y., Beagley, Kenneth W., Preston, Julie A., Gibson, Peter G., Foster, Paul S., Hansbro, Philip M.

Chronic cigarette smoke exposure induces systemic hypoxia that drives intestinal dysfunction

- Fricker, Michael, Goggins, Bridie J., Talley, Nicholas J., Walker, Marjorie M., Keely, Simon, Hansbro, Philip M., Mateer, Sean, Jones, Bernadette, Kim, Richard Y., Gellatly, Shaan L., Jarnicki, Andrew G., Powell, Nicholas, Oliver, Brian G., Radford-Smith, Graham

Critical role for iron accumulation in the pathogenesis of fibrotic lung disease

- Ali, Md Khadem, Kim, Richard Y., Borghuis, Theo, Karim, Rafia, Pinkerton, James W., Aryal, Ritambhara, Heidari, Moones, Martin, Kristy L., Burgess, Janette K., Oliver, Brian G., Trinder, Debbie, Johnstone, Daniel M., Brown, Alexandra C., Milward, Elizabeth A., Hansbro, Philip M., Horvat, Jay C., Donovan, Chantal, Vanka, Kanth S., Mayall, Jemma R., Liu, Gang, Pillar, Amber L., Jones-Freeman, Bernadette, Xenaki, Dikaia

Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma

- Ali, Md Khadem, Kim, Richard Y., Donovan, Chantal, Pathinayake, Prabuddha S., Carroll, Olivia R., Trinder, Debbie, Tay, Hock L., Badi, Yusef E., Kermani, Nazanin Z., Guo, Yi-Ke, Aryal, Ritambhara, Mumby, Sharon, Brown, Alexandra C., Pavlidis, Stelios, Adcock, IM, Weaver, Jessica, Xenaki, D, Oliver, BG, Holliday, Elizabeth G., Foster, Peter S., Wark, Peter A., Johnstone, DM, Milward, EA, Mayall, Jemma R., Hansbro, Philip M., Horvat, Jay C., Karim, Rafia, Pinkerton, James W., Liu, Gang, Martin, Kristy L., Starkey, Malcolm R., Pillar, Amber L.

Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease

- Bowerman, Kate L., Rehman, Saima Firdous, Yang, Ian A., Wark, Peter A., Hugenholtz, Philip, Hansbro, Philip M., Vaughan, Annalicia, Lachner, Nancy, Budden, Kurtis F., Kim, Richard Y., Wood, David L. A., Gellatly, Shaan L., Shukla, Shakti D., Wood, Lisa G.

Early-life chlamydial lung infection enhances allergic airways disease through age-dependent differences in immunopathology

- Horvat, Jay C., Starkey, Malcolm R., Kim, Richard Y., Phipps, Simon, Gibson, Peter G., Beagley, Kenneth W., Foster, Paul S., Hansbro, Philip M.

Elucidating novel disease mechanisms in severe asthma

- Kim, Richard Y., Rae, Brittany, Neal, Rachel, Donovan, Chantal, Pinkerton, James, Balachandran, Lohis, Starkey, Malcolm R., Knight, Darryl A., Horvat, Jay C., Hansbro, Philip M.

Emerging therapeutic targets and preclinical models for severe asthma

- Galvao, Izabela, Kim, Richard Y., Shen, Sijie, Budden, Kurtis F., Vieira, Angélica T., Hansbro, Philip M.

Fibulin-1 regulates the pathogenesis of tissue remodeling in respiratory diseases

- Liu, Gang, Cooley, Marion A., Tjin, Gavin, Wark, Peter A. B., Walker, Marjorie M., Horvat, Jay C., Oliver, Brian G., Argraves, W. Scott, Knight, Darryl A., Burgess, Janette K., Hansbro, Philip M., Jarnicki, Andrew G., Hsu, Alan C-Y., Nair, Prema M., Haw, Tatt Jhong, FRICKER, Michael, Gellatly, Shaan L., Kim, Richard Y., Inman, Mark D.

Human beta-defensin-2 suppresses key features of asthma in murine models of allergic airways disease

- Pinkerton, James W., Kim, Richard Y., Nordkild, Peter, Horvat, Jay C., Jensen, Benjanim A. H., Wehkamp, Jan, Hansbro, Philip M., Koeninger, Louis, Armbruster, Nicole S., Hansbro, Nicole G., Brown, Alexandra C., Jayaraman, Ranjith, Shen, Sijie, Malek, Nisar, Cooper, Matthew A.

IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis

- Starkey, Malcolm R., Plank, Maximilian W., Donovan, Chantal, Hansbro, Nicole G., Nguyen, Duc H., Nair, Prema Mono, Kim, Richard Y., Horvat, Jay C., Kaiko, Gerard E., Durum, Scott K., Wark, Peter A., Sin, Don D., Casolari, Paolo, Caramori, Gaetano, Adcock, Ian M., Foster, Paul S., Hansbro, Philip M., Papi, Alberto, Pavlidis, Stelios, Guo, Yike, Cameron, Guy J. M., Haw, Tatt Jhong, Tam, Anthony, Obiedat, Maen

IL-6 drives neutrophil-mediated pulmonary inflammation associated with bacteremia in murine models of colitis

- Mateer, Sean W., Mathe, Andrea, Kim, Richard Y., Minahan, Kyra, Walker, Marjorie M., Callister, Robert C., Foster, Paul S., Horvat, Jay C., Hansbro, Philip M., Keely, Simon, Bruce, Jessica, Liu, Gang, Maltby, Steven, Fricker, Michael, Goggins, Bridie J., Tay, Hock L., Marks, Ellen, Burns, Grace

Inflammasomes in COPD and neutrophilic asthma

- Kim, Richard Y., Pinkerton, James W., Gibson, Peter G., Cooper, Matthew A., Horvat, Jay C., Hansbro, Philip M.

Inflammasomes in the lung

- Pinkerton, James W., Kim, Richard Y., Robertson, Avril A. B., Hirota, Jeremy A., Wood, Lisa G., Knight, Darryl A., Cooper, Matthew A., O'Neill, Luke A. J., Horvat, Jay C., Hansbro, Philip M.