A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis

- Beckett, Emma L., Stevens, Richard L., Oliver, Brian G., van Rooijen, Nico, Inman, Mark D., Adachi, Roberto, Soberman, Roy J., Hamadi, Sahar, Wark, Peter A., Foster, Paul S., Hansbro, Philip M., Jarnicki, Andrew G., Kim, Richard Y., Hanish, Irwan, Hansbro, Nicole G., Deane, Andrew, Keely, Simon, Horvat, Jay C., Yang, Ming

Adverse roles of mast cell chymase-1 in chronic obstructive pulmonary disease

- Liu, Gang, Jarnicki, Andrew G., Paudel, Keshav R., Lu, Wenying, Wadhwa, Ridhima, Philp, Ashleigh M., Van Eeckhoutte, Hannelore, Marshall, Jacqueline E., Malyla, Vamshikrishna, Katsifis, Angelica, Fricker, Michael, Hansbro, Nicole G., Dua, Kamal, Kermani, Nazanin Z., Eapen, Mathew S., Tiotiu, Angelica, Chung, K. Fan, Caramori, Gaetano, Bracke, Ken, Adcock, Ian M., Wark, Peter A., Hansbro, Philip M.

Aim2 suppresses cigarette smoke-induced neutrophil recruitment, neutrophil caspase-1 activation and anti-Ly6G-mediated neutrophil depletion

- Donovan, Chantal, Kim, Richard Y, Khan, Haroon, Pickles, Sophie, Sahu, Priyanka, Chimankar, Vrushali, Tu, Xiaofan, Ali, Md Khadem, Mayall, Jemma R., Nguyen, Duc H., Budden, Kurtis F., Kumar, Vinod, Galvao, Izabela, Wark, Peter A. B., Horvat, Jay C., Hansbro, Philip M., Ab Wark, P, Oliver, BG, Horvat, JC, Hansbro, PM, Jarnicki, Andrew G., Brown, Alexandra C., Jones-Freeman, Bernadette, Gomez, Henry M., Wadhwa, Ridhima, Hortle, Elinor, Jayaraman, Ranjith

Airway remodelling and inflammation in asthma are dependent on the extracellular matrix protein fibulin-1c

- Liu, Gang, Cooley, Marion A., Tay, Hock, Foster, Paul S., Wark, Peter A., Horvat, Jay C., Bourke, Jane E., Grainge, Chris L., Argraves, W. Scott, Oliver, Brian G., Knight, Darryl A., Burgess, Janette K., Nair, Prema M., Hansbro, Philip M., Donovan, Chantal, Hsu, Alan C., Jarnicki, Andrew G., Haw, Tatt Jhong, Hansbro, Nicole G., Ge, Qi, Brown, Alexandra C.

Chronic cigarette smoke exposure induces systemic hypoxia that drives intestinal dysfunction

- Fricker, Michael, Goggins, Bridie J., Talley, Nicholas J., Walker, Marjorie M., Keely, Simon, Hansbro, Philip M., Mateer, Sean, Jones, Bernadette, Kim, Richard Y., Gellatly, Shaan L., Jarnicki, Andrew G., Powell, Nicholas, Oliver, Brian G., Radford-Smith, Graham

Fibulin-1 regulates the pathogenesis of tissue remodeling in respiratory diseases

- Liu, Gang, Cooley, Marion A., Tjin, Gavin, Wark, Peter A. B., Walker, Marjorie M., Horvat, Jay C., Oliver, Brian G., Argraves, W. Scott, Knight, Darryl A., Burgess, Janette K., Hansbro, Philip M., Jarnicki, Andrew G., Hsu, Alan C-Y., Nair, Prema M., Haw, Tatt Jhong, FRICKER, Michael, Gellatly, Shaan L., Kim, Richard Y., Inman, Mark D.

Fibulin-1c regulates transforming growth factor-beta activation in pulmonary tissue fibrosis

- Liu, Gang, Cooley, Marion A., Jones, Berrnadette, Hansbro, Nicole G., Wark, Peter A., Horvat, Jay C., Argraves, W. Scott, Oliver, Brian G., Knight, Darryl A., Burgess, Janette K., Hansbro, Philip M., Jarnicki, Andrew G., Borghuis, Theo, Nair, Prema M., Tjin, Gavin, Hsu, Alan C., Haw, Tatt Jhong, Fricker, Michael, Harrison, Celeste L.

Identification and optimization of mechanism-based fluoroallylamine inhibitors of lysyl oxidase-like 2/3

- Findlay, Alison D., Foot, Jonathan S., Buson, Alberto, Deodhar, Mandar, Jarnicki, Andrew G., Hansbro, Philip M., Liu, Gang, Schilter, Heidi, Turner, Craig I., Zhou, Wenbin, Jarolimek, Wolfgang

Importance of mast cell Prss31/transmembrane tryptase/tryptase-γ in lung function and experimental chronic obstructive pulmonary disease and colitis

- Hansbro, Philip M., Hamilton, Matthew J., Foster, Paul S., Krilis, Steven A., Stevens, Richard L., Fricker, Michael, Gellatly, Shaan L., Jarnicki, Andrew G., Zheng, Dominick, Frei, Sandra M., Wong, G. William, Hamadi, Sahar, Zhou, Saijun

Macrolides for macrophages in chronic obstructive pulmonary disease

- Hansbro, Philip M., Jarnicki, Andrew G.

Maternal smoke exposure impairs the long-term fertility of a female offspring in a murine model

- Camlin, Nicole J., Sobinoff, Alexander P., Sutherland, Jessie M., Beckett, Emma L., Jarnicki, Andrew G., Vanders, Rebecca L., Hansbro, Philip M., McLaughlin, Eileen A., Holt, Janet E.

Maternal smoke exposure impairs the long-term fertility of female offspring in a murine model

- Camlin, Nicole J., Sobinoff, Alexander P., Sutherland, Jessie M., Beckett, Emma L., Jarnicki, Andrew G., Vanders, Rebecca L., Hansbro, Philip M., McLaughlin, Eileen A., Holt, Janet E.

MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase-mediated suppression of histone deacetylase 2

- Kim, Richard Y., Horvat, Jay C., Sunkara, Krishna P., Nguyen, Thi Hiep, Jarnicki, Andrew G., Keely, Simon, Mattes, Joerg, Adcock, Ian M., Foster, Paul S., Hansbro, Philip M., Pinkerton, James W., Starkey, Malcolm R., Essilfie, Ama T., Mayall, Jemma R., Nair, Prema M., Hansbro, Nicole G., Jones, Bernadette, Haw, Tatt Jhong

microRNA-21-mediated SATB1/S100A9/NF-kappa B axis promotes chronic obstructive pulmonary disease pathogenesis

- Kim, Richard Y., Sunkara, Krishna P., Ricciardolo, Fabio L. M., Di Stefano, Antonino, Haw, Tatt Jhong, Liu, Gang, Ferguson, Angela L., Palendira, Umamainthan, Wark, Peter A., Conickx, Griet, Mestdagh, Pieter, Brusselle, Guy G., Bracke, Ken R., Caramori, Gaetano, Foster, Paul S., Horvat, Jay C., Hansbro, Philip M., Jarnicki, Andrew G., Donovan, Chantal, Hsu, Alan C., Ieni, Antonio, Beckett, Emma L., Galvão, Izabela, Wijnant, Sara

Mitochondrial DNA neutrophil extracellular traps are formed after trauma and subsequent surgery

- McIlroy, Daniel J., Jarnicki, Andrew G., Au, Gough G., Lott, Natalie, Smith, Doug W., Hansbro, Philip M., Balogh, Zsolt J.

Programming of formalin-induced nociception by neonatal LPS exposure: maintenance by peripheral and central neuroimmune activity

- Zouikr, Ihssane, Ahmed, Abdulrzag F., Horvat, Jay C., Beagley, Kenneith W., Cllifton, Vicki L., Ray, Allyson, Thorne, Rick F., Jarnicki, Andrew G., Hansbro, Philip M., Hidgson, Deborah M.

The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.

- Franklin, Bernado S., Bossaller, Lukas, Mangan, Matthew S., Zimmer, Sebastian, Monks, Brian G., Fricke, Martin, Schmidt, Reinhold E., Espevik, Terje, Jones, Bernadette, Jarnicki, Andrew G., Hansbro, Philip M., Busto, Patricia, De Nardo, Dominic, Marshak-Rothstein, Ann, Hornemann, Simone, Aguzzi, Adriano, Kastenmüller, Wolfgang, Latz, Eicke, Ratter, Jacqueline M., Stutz, Andrea, Engels, Gudrun, Brenker, Christoph, Nordhoff, Mark, Mirandola, Sandra R., Al-Amoudi, Ashraf

Time-resolved proteomic profiling of cigarette smoke-induced experimental chronic obstructive pulmonary disease

- Skerrett-Byrne, David A., Bromfield, Elizabeth G., Anderson, Amanda L., Nixon, Brett, Scott, Rodney J., Wark, Peter A. B., Dun, Matthew D., Hansbro, Philip M., Murray, Heather C., Jamaluddin, M. Fairuz B., Jarnicki, Andrew G., Fricker, Michael, Essilfie, Ama T., Jones, Bernadette, Haw, Tatt J., Hampsey, Daniel

TLR2, TLR4 AND MyD88 mediate allergic airway disease (AAD) and Streptococcus pneumoniae-induced suppression of AAD

- Thorburn, Alison N., Tseng, Hsin-Yi, Donovan, Chantal, Hansbro, Nicole G., Jarnicki, Andrew G., Foster, Paul S., Gibson, Peter G., Hansbro, Philip M.