Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages
- Runtsch, Marah C., Angiari, Stefano, Mendez, Rui Santalla, Zotta, Alessia, Peace, Christian G., Walsh, Aoife, Chirillo, Roberta, Hams, Emily, Fallon, Padraic G., Jayamaran, Ranjith, Dua, Kamal, Brown, Alexandra C., Hooftman, Alexander, Kim, Richard Y., Horvat, Jay C., Hansbro, Philip M., Wang, C, O'Neill, LAJ, Wadhwa, Ridhima, Zhang, Yanling, Zheng, Yunan, Spina, Joseph S., Ruzek, Melanie C., Argiriadi, Maria A., McGettrick, Anne F.
- Creator: Runtsch, Marah C. , Angiari, Stefano , Mendez, Rui Santalla , Zotta, Alessia , Peace, Christian G. , Walsh, Aoife , Chirillo, Roberta , Hams, Emily , Fallon, Padraic G. , Jayamaran, Ranjith , Dua, Kamal , Brown, Alexandra C. , Hooftman, Alexander , Kim, Richard Y. , Horvat, Jay C. , Hansbro, Philip M. , Wang, C , O'Neill, LAJ , Wadhwa, Ridhima , Zhang, Yanling , Zheng, Yunan , Spina, Joseph S. , Ruzek, Melanie C. , Argiriadi, Maria A. , McGettrick, Anne F.
- Resource Type: journal article
- Date: 2022
Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma
- Ali, Md Khadem, Kim, Richard Y., Donovan, Chantal, Pathinayake, Prabuddha S., Carroll, Olivia R., Trinder, Debbie, Tay, Hock L., Badi, Yusef E., Kermani, Nazanin Z., Guo, Yi-Ke, Aryal, Ritambhara, Mumby, Sharon, Brown, Alexandra C., Pavlidis, Stelios, Adcock, IM, Weaver, Jessica, Xenaki, D, Oliver, BG, Holliday, Elizabeth G., Foster, Peter S., Wark, Peter A., Johnstone, DM, Milward, EA, Mayall, Jemma R., Hansbro, Philip M., Horvat, Jay C., Karim, Rafia, Pinkerton, James W., Liu, Gang, Martin, Kristy L., Starkey, Malcolm R., Pillar, Amber L.
- Creator: Ali, Md Khadem , Kim, Richard Y. , Donovan, Chantal , Pathinayake, Prabuddha S. , Carroll, Olivia R. , Trinder, Debbie , Tay, Hock L. , Badi, Yusef E. , Kermani, Nazanin Z. , Guo, Yi-Ke , Aryal, Ritambhara , Mumby, Sharon , Brown, Alexandra C. , Pavlidis, Stelios , Adcock, IM , Weaver, Jessica , Xenaki, D , Oliver, BG , Holliday, Elizabeth G. , Foster, Peter S. , Wark, Peter A. , Johnstone, DM , Milward, EA , Mayall, Jemma R. , Hansbro, Philip M. , Horvat, Jay C. , Karim, Rafia , Pinkerton, James W. , Liu, Gang , Martin, Kristy L. , Starkey, Malcolm R. , Pillar, Amber L.
- Resource Type: journal article
- Date: 2020
Role for NLRP3 inflammasome-mediated, IL-1ß-dependent responses in severe, steroid-resistant asthma
- Kim, Richard Y., Pinkerton, James W., Hirota, Jeremy A., Wood, Lisa G., Simpson, Jodie L., Knight, Darryl A., Wark, Peter A., Gibson, Peter G., O'Neill, Luke A. J., Cooper, Matthew A., Horvat, Jay C., Hansbro, Philip M., Essilfie, Ama T., Robertson, Avril A. B., Baines, Katherine J., Brown, Alexandra C., Mayall, Jemma R., Ali, M. Khadem, Starkey, Malcolm R., Hansbro, Nicole G.
- Creator: Kim, Richard Y. , Pinkerton, James W. , Hirota, Jeremy A. , Wood, Lisa G. , Simpson, Jodie L. , Knight, Darryl A. , Wark, Peter A. , Gibson, Peter G. , O'Neill, Luke A. J. , Cooper, Matthew A. , Horvat, Jay C. , Hansbro, Philip M. , Essilfie, Ama T. , Robertson, Avril A. B. , Baines, Katherine J. , Brown, Alexandra C. , Mayall, Jemma R. , Ali, M. Khadem , Starkey, Malcolm R. , Hansbro, Nicole G.
- Resource Type: journal article
- Date: 2017
- Liu, Gang, Cooley, Marion A., Tay, Hock, Foster, Paul S., Wark, Peter A., Horvat, Jay C., Bourke, Jane E., Grainge, Chris L., Argraves, W. Scott, Oliver, Brian G., Knight, Darryl A., Burgess, Janette K., Nair, Prema M., Hansbro, Philip M., Donovan, Chantal, Hsu, Alan C., Jarnicki, Andrew G., Haw, Tatt Jhong, Hansbro, Nicole G., Ge, Qi, Brown, Alexandra C.
- Creator: Liu, Gang , Cooley, Marion A. , Tay, Hock , Foster, Paul S. , Wark, Peter A. , Horvat, Jay C. , Bourke, Jane E. , Grainge, Chris L. , Argraves, W. Scott , Oliver, Brian G. , Knight, Darryl A. , Burgess, Janette K. , Nair, Prema M. , Hansbro, Philip M. , Donovan, Chantal , Hsu, Alan C. , Jarnicki, Andrew G. , Haw, Tatt Jhong , Hansbro, Nicole G. , Ge, Qi , Brown, Alexandra C.
- Resource Type: journal article
- Date: 2017
Generation of cardio-protective antibodies after pneumococcal polysaccharide vaccine: Early results from a randomised controlled trial
- Ren, Shu, Hansbro, Philip M., Srikusalanukul, Wichat, Horvat, Jay C., Hunter, Tegan, Brown, Alexandra C., Peel, Roseanne, Faulkner, Jack, Evans, Tiffany-Jane, Li, Shu Chuen, Newby, David, Hure, Alexis, Abhayaratna, Walter P., Tsimikas, Sotirios, Gonen, Ayelet, Witztum, Joseph L., Attia, John
- Creator: Ren, Shu , Hansbro, Philip M. , Srikusalanukul, Wichat , Horvat, Jay C. , Hunter, Tegan , Brown, Alexandra C. , Peel, Roseanne , Faulkner, Jack , Evans, Tiffany-Jane , Li, Shu Chuen , Newby, David , Hure, Alexis , Abhayaratna, Walter P. , Tsimikas, Sotirios , Gonen, Ayelet , Witztum, Joseph L. , Attia, John
- Resource Type: journal article
- Date: 2022
- Creator: Ren, Shu , Hansbro, Philip M. , Srikusalanukul, Wichat , Horvat, Jay C. , Hunter, Tegan , Brown, Alexandra C. , Peel, Roseanne , Faulkner, Jack , Evans, Tiffany-Jane , Li, Shu Chuen , Newby, David , Hure, Alexis , Abhayaratna, Walter P. , Tsimikas, Sotirios , Gonen, Ayelet , Witztum, Joseph L. , Attia, John
- Resource Type: journal article
- Date: 2022
- Thorburn, Alison N., Brown, Alexandra C., Nair, Prema M., Chevalier, Nina, Foster, Paul S., Gibson, Peter G., Hansbro, Philip M.
- Creator: Thorburn, Alison N. , Brown, Alexandra C. , Nair, Prema M. , Chevalier, Nina , Foster, Paul S. , Gibson, Peter G. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2013
- Simpson, Jodie L., Baines, Katherine J., Horvat, Jay C., Essilfie, Ama-Tawiah, Brown, Alexandra C., Tooze, Melinda, McDonald, Vanessa M., Gibson, Peter G., Hansbro, Philip M.
- Creator: Simpson, Jodie L. , Baines, Katherine J. , Horvat, Jay C. , Essilfie, Ama-Tawiah , Brown, Alexandra C. , Tooze, Melinda , McDonald, Vanessa M. , Gibson, Peter G. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2016
- Pathinayake, Prabuddha S., Waters, David W., Gibson, Peter G., Hansbro, Philip M., Wark, Peter A. B., Nichol, Kristy S., Brown, Alexandra C., Reid, Andrew T., Hsu, Alan Chen-Yu, Horvat, Jay C., Wood, Lisa G., Baines, Katherine J., Simpson, Jodie L.
- Creator: Pathinayake, Prabuddha S. , Waters, David W. , Gibson, Peter G. , Hansbro, Philip M. , Wark, Peter A. B. , Nichol, Kristy S. , Brown, Alexandra C. , Reid, Andrew T. , Hsu, Alan Chen-Yu , Horvat, Jay C. , Wood, Lisa G. , Baines, Katherine J. , Simpson, Jodie L.
- Resource Type: journal article
- Date: 2021
Critical role for iron accumulation in the pathogenesis of fibrotic lung disease
- Ali, Md Khadem, Kim, Richard Y., Borghuis, Theo, Karim, Rafia, Pinkerton, James W., Aryal, Ritambhara, Heidari, Moones, Martin, Kristy L., Burgess, Janette K., Oliver, Brian G., Trinder, Debbie, Johnstone, Daniel M., Brown, Alexandra C., Milward, Elizabeth A., Hansbro, Philip M., Horvat, Jay C., Donovan, Chantal, Vanka, Kanth S., Mayall, Jemma R., Liu, Gang, Pillar, Amber L., Jones-Freeman, Bernadette, Xenaki, Dikaia
- Creator: Ali, Md Khadem , Kim, Richard Y. , Borghuis, Theo , Karim, Rafia , Pinkerton, James W. , Aryal, Ritambhara , Heidari, Moones , Martin, Kristy L. , Burgess, Janette K. , Oliver, Brian G. , Trinder, Debbie , Johnstone, Daniel M. , Brown, Alexandra C. , Milward, Elizabeth A. , Hansbro, Philip M. , Horvat, Jay C. , Donovan, Chantal , Vanka, Kanth S. , Mayall, Jemma R. , Liu, Gang , Pillar, Amber L. , Jones-Freeman, Bernadette , Xenaki, Dikaia
- Resource Type: journal article
- Date: 2020
- Creator: Ali, Md Khadem , Kim, Richard Y. , Borghuis, Theo , Karim, Rafia , Pinkerton, James W. , Aryal, Ritambhara , Heidari, Moones , Martin, Kristy L. , Burgess, Janette K. , Oliver, Brian G. , Trinder, Debbie , Johnstone, Daniel M. , Brown, Alexandra C. , Milward, Elizabeth A. , Hansbro, Philip M. , Horvat, Jay C. , Donovan, Chantal , Vanka, Kanth S. , Mayall, Jemma R. , Liu, Gang , Pillar, Amber L. , Jones-Freeman, Bernadette , Xenaki, Dikaia
- Resource Type: journal article
- Date: 2020
Investigating the links between lower iron status in pregnancy and respiratory disease in offspring using murine models
- Gomez, Henry M., Pillar, Amber L., Brown, Alexandra C., Kim, Richard Y., Ali, Md Khadem, Essilfie, Ama-Tawiah, Vanders, Rebecca, Frazer, David M., Anderson, Gregory J., Hansbro, Philip M., Collison, Adam M., Jensen, Megan E., Murphy, Vanessa E., Johnstone, Daniel M., Reid, David, Milward, Elizabeth A., Donovan, Chantal, Horvat, Jay C.
- Creator: Gomez, Henry M. , Pillar, Amber L. , Brown, Alexandra C. , Kim, Richard Y. , Ali, Md Khadem , Essilfie, Ama-Tawiah , Vanders, Rebecca , Frazer, David M. , Anderson, Gregory J. , Hansbro, Philip M. , Collison, Adam M. , Jensen, Megan E. , Murphy, Vanessa E. , Johnstone, Daniel M. , Reid, David , Milward, Elizabeth A. , Donovan, Chantal , Horvat, Jay C.
- Resource Type: journal article
- Date: 2021
- Creator: Gomez, Henry M. , Pillar, Amber L. , Brown, Alexandra C. , Kim, Richard Y. , Ali, Md Khadem , Essilfie, Ama-Tawiah , Vanders, Rebecca , Frazer, David M. , Anderson, Gregory J. , Hansbro, Philip M. , Collison, Adam M. , Jensen, Megan E. , Murphy, Vanessa E. , Johnstone, Daniel M. , Reid, David , Milward, Elizabeth A. , Donovan, Chantal , Horvat, Jay C.
- Resource Type: journal article
- Date: 2021
Visualization of endogenous p27 and Ki67 reveals the importance of a c-Myc-driven metabolic switch in promoting survival of quiescent cancer cells
- La, Ting, Chen, Song, Brown, Alexandra C., Zhang, Didi, Dong, Qihan, Wang, Jenny Y., Cao, Huixia, Liu, Tao, Thorne, Rick F., Shao, Feng-Min, Zhang, Xu Dong, Jin, Lei, Guo, Tao, Zhao, Xiao Hong, Teng, Liu, Li, Dandan, Carnell, Michael, Zhang, Yuan Yuan, Feng, Yu Chen, Cole, Nicole
- Creator: La, Ting , Chen, Song , Brown, Alexandra C. , Zhang, Didi , Dong, Qihan , Wang, Jenny Y. , Cao, Huixia , Liu, Tao , Thorne, Rick F. , Shao, Feng-Min , Zhang, Xu Dong , Jin, Lei , Guo, Tao , Zhao, Xiao Hong , Teng, Liu , Li, Dandan , Carnell, Michael , Zhang, Yuan Yuan , Feng, Yu Chen , Cole, Nicole
- Resource Type: journal article
- Date: 2021
- Creator: La, Ting , Chen, Song , Brown, Alexandra C. , Zhang, Didi , Dong, Qihan , Wang, Jenny Y. , Cao, Huixia , Liu, Tao , Thorne, Rick F. , Shao, Feng-Min , Zhang, Xu Dong , Jin, Lei , Guo, Tao , Zhao, Xiao Hong , Teng, Liu , Li, Dandan , Carnell, Michael , Zhang, Yuan Yuan , Feng, Yu Chen , Cole, Nicole
- Resource Type: journal article
- Date: 2021
Sex steroids induce membrane stress responses and virulence properties in pseudomonas aeruginosa
- Vidaillac, Celine, Yong, Valerie Fei Lee, Sankaran, Jagadish, Foo, Yong Hwee, Righetti, Francesco, Nedumaran, Anu Maashaa, Aogáin, Micheal Mac, Roizman, Dan, Richard, Jean-Alexandre, Rogers, Thomas R., Toyofuku, Masanori, Luo, Dahai, Aschtgen, Marie-Stephanie, Loh, E, Wohland, T, Czarny, B, Horvat, Jay C., Hansbro, Philip M., Yang, L, Li, L, Normark, S, Normark, BH, Chotirmall, SH, Qu, Jing, Yang, Shuowei, Xu, Guangfu, Seng, Zi Jing, Brown, Alexandra C., Ali, Md Khadem, Jaggi, Tavleen K.
- Creator: Vidaillac, Celine , Yong, Valerie Fei Lee , Sankaran, Jagadish , Foo, Yong Hwee , Righetti, Francesco , Nedumaran, Anu Maashaa , Aogáin, Micheal Mac , Roizman, Dan , Richard, Jean-Alexandre , Rogers, Thomas R. , Toyofuku, Masanori , Luo, Dahai , Aschtgen, Marie-Stephanie , Loh, E , Wohland, T , Czarny, B , Horvat, Jay C. , Hansbro, Philip M. , Yang, L , Li, L , Normark, S , Normark, BH , Chotirmall, SH , Qu, Jing , Yang, Shuowei , Xu, Guangfu , Seng, Zi Jing , Brown, Alexandra C. , Ali, Md Khadem , Jaggi, Tavleen K.
- Resource Type: journal article
- Date: 2020
- Donovan, Chantal, Kim, Richard Y, Khan, Haroon, Pickles, Sophie, Sahu, Priyanka, Chimankar, Vrushali, Tu, Xiaofan, Ali, Md Khadem, Mayall, Jemma R., Nguyen, Duc H., Budden, Kurtis F., Kumar, Vinod, Galvao, Izabela, Wark, Peter A. B., Horvat, Jay C., Hansbro, Philip M., Ab Wark, P, Oliver, BG, Horvat, JC, Hansbro, PM, Jarnicki, Andrew G., Brown, Alexandra C., Jones-Freeman, Bernadette, Gomez, Henry M., Wadhwa, Ridhima, Hortle, Elinor, Jayaraman, Ranjith
- Creator: Donovan, Chantal , Kim, Richard Y , Khan, Haroon , Pickles, Sophie , Sahu, Priyanka , Chimankar, Vrushali , Tu, Xiaofan , Ali, Md Khadem , Mayall, Jemma R. , Nguyen, Duc H. , Budden, Kurtis F. , Kumar, Vinod , Galvao, Izabela , Wark, Peter A. B. , Horvat, Jay C. , Hansbro, Philip M. , Ab Wark, P , Oliver, BG , Horvat, JC , Hansbro, PM , Jarnicki, Andrew G. , Brown, Alexandra C. , Jones-Freeman, Bernadette , Gomez, Henry M. , Wadhwa, Ridhima , Hortle, Elinor , Jayaraman, Ranjith
- Resource Type: journal article
- Date: 2022
PD-L1 promotes early-life chlamydia respiratory infection-induced severe allergic airway disease
- Starkey, Malcolm R., Nguyen, Duc H., Brown, Alexandra C., Essilfie, Ama-Tawiah, Kim, Richard Y., Yagita, Hideo, Horvat, Jay C., Hansbro, Philip M.
- Creator: Starkey, Malcolm R. , Nguyen, Duc H. , Brown, Alexandra C. , Essilfie, Ama-Tawiah , Kim, Richard Y. , Yagita, Hideo , Horvat, Jay C. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2016
Polycomb repressive complex 2 is a critical mediator of allergic inflammation
- Keenan, Christine R., Iannarella, Nadia, Garnham, Alexandra L., Brown, Alexandra C., Kim, Richard Y., Horvat, Jay C., Hansbro, Philip M., Nutt, Stephen L., Allan, Rhys S.
- Creator: Keenan, Christine R. , Iannarella, Nadia , Garnham, Alexandra L. , Brown, Alexandra C. , Kim, Richard Y. , Horvat, Jay C. , Hansbro, Philip M. , Nutt, Stephen L. , Allan, Rhys S.
- Resource Type: journal article
- Date: 2019
- Scott, Hayley A., Ng, Shawn H. M., McLoughlin, Rebecca F., Valkenborghs, Sarah R., Nair, Parameswaran, Brown, Alexandra C., Carroll, Olivia R., Horvat, Jay C., Wood, Lisa G.
- Creator: Scott, Hayley A. , Ng, Shawn H. M. , McLoughlin, Rebecca F. , Valkenborghs, Sarah R. , Nair, Parameswaran , Brown, Alexandra C. , Carroll, Olivia R. , Horvat, Jay C. , Wood, Lisa G.
- Resource Type: journal article
- Date: 2023
Glycemic variability in diabetes increases the severity of influenza
- Marshall, Rebecca J., Armart, Pornthida, Gallo, Linda A., Short, Kirsty R., Hulme, Katina D., Chew, Keng Ylh, Brown, Alexandra C., Hansbro, Philip M., Bloxham, Conor J., Flint, Melanie, Ronacher, Katharina, Bielefeldt-Ohmann, Helle
- Creator: Marshall, Rebecca J. , Armart, Pornthida , Gallo, Linda A. , Short, Kirsty R. , Hulme, Katina D. , Chew, Keng Ylh , Brown, Alexandra C. , Hansbro, Philip M. , Bloxham, Conor J. , Flint, Melanie , Ronacher, Katharina , Bielefeldt-Ohmann, Helle
- Resource Type: journal article
- Date: 2020
Airway and parenchyma transcriptomics in a house dust mite model of experimental asthma
- Tu, Xiaofan, Gomez, Henry M., Donovan, Chantal, Kim, Richard Y., Brown, Alexandra C., de Jong, Emma, Galvao, Izabela, Faiz, Alen, Bosco, Anthony, Horvat, Jay C., Hansbro, Philip
- Creator: Tu, Xiaofan , Gomez, Henry M. , Donovan, Chantal , Kim, Richard Y. , Brown, Alexandra C. , de Jong, Emma , Galvao, Izabela , Faiz, Alen , Bosco, Anthony , Horvat, Jay C. , Hansbro, Philip
- Resource Type: journal article
- Date: 2023
Human beta-defensin-2 suppresses key features of asthma in murine models of allergic airways disease
- Pinkerton, James W., Kim, Richard Y., Nordkild, Peter, Horvat, Jay C., Jensen, Benjanim A. H., Wehkamp, Jan, Hansbro, Philip M., Koeninger, Louis, Armbruster, Nicole S., Hansbro, Nicole G., Brown, Alexandra C., Jayaraman, Ranjith, Shen, Sijie, Malek, Nisar, Cooper, Matthew A.
- Creator: Pinkerton, James W. , Kim, Richard Y. , Nordkild, Peter , Horvat, Jay C. , Jensen, Benjanim A. H. , Wehkamp, Jan , Hansbro, Philip M. , Koeninger, Louis , Armbruster, Nicole S. , Hansbro, Nicole G. , Brown, Alexandra C. , Jayaraman, Ranjith , Shen, Sijie , Malek, Nisar , Cooper, Matthew A.
- Resource Type: journal article
- Date: 2020
Characterization and inhibition of inflammasome responses in severe and non-severe asthma
- Horvat, Jay C., Kim, Richard Y., Weaver, Natasha, Augood, Christopher, Brown, Alexandra C., Donovan, Chantal, Dupre, Pierrick, Gunawardhana, Lakshitha, Mayall, Jemma R., Hansbro, Nicole G., Robertson, Avril A. B., O'Neill, Luke A. J., Cooper, Matthew A., Holliday, Elizabeth G., Hansbro, Philip M., Gibson, Peter G.
- Creator: Horvat, Jay C. , Kim, Richard Y. , Weaver, Natasha , Augood, Christopher , Brown, Alexandra C. , Donovan, Chantal , Dupre, Pierrick , Gunawardhana, Lakshitha , Mayall, Jemma R. , Hansbro, Nicole G. , Robertson, Avril A. B. , O'Neill, Luke A. J. , Cooper, Matthew A. , Holliday, Elizabeth G. , Hansbro, Philip M. , Gibson, Peter G.
- Resource Type: journal article
- Date: 2023
- Creator: Horvat, Jay C. , Kim, Richard Y. , Weaver, Natasha , Augood, Christopher , Brown, Alexandra C. , Donovan, Chantal , Dupre, Pierrick , Gunawardhana, Lakshitha , Mayall, Jemma R. , Hansbro, Nicole G. , Robertson, Avril A. B. , O'Neill, Luke A. J. , Cooper, Matthew A. , Holliday, Elizabeth G. , Hansbro, Philip M. , Gibson, Peter G.
- Resource Type: journal article
- Date: 2023