No additional prognostic value of genetic information in the prediction of vascular events after cerebral ischemia of arterial origin: The PROMISe study

- Achterberg, Sefanja, Kappelle, L. Jaap, Mali, W.P.T.M., Doevendans, P.A., Farrall, Martin, Holliday, Elizabeth G., Sudlow, Cathie, Hopewell, Jemma C., Cheng, Yu-Ching, Fornage, Myriam, Ikram, M. Arfan, Malik, Rainer, De Bakker, Paul I. W., Bevan, Steve, Thorsteinsdottir, Unnur, DeStefano, Anita L., Worrall, Bradford B., Reiner, Alex P., Mitchell, Braxtin D., Clarke, Robert, Levi, Christopher, Seshadri, Sudha, Boncoraglio, Giorgio B., Traylor, Matthew, Sharma, Pankaj, Bis, Joshua C., Gretarsdottir, Solveig, Psaty, Bruce M., Rothwell, Peter M., Rosand, Jonathan, Meschia, James F., Stefansson, Kari, Dichgans, Martin, Markus, Hugh S., Algra, Ale, Van Der Graaf, Y., Grobbee, D.E., Rutten, G.E.H.M., Visseren, F.L.J., Moll, F.L.

Genetic architecture of white matter hyperintensities differs in hypertensive and nonhypertensive ischemic stroke

- Adib-Samii, Poneh, Devan, William, Rothwell, Peter M., Sudlow, Cathie, Boncoraglio, Giorgio B., Meschia, James F., Levi, Chris, Dichgans, Martin, Bevan, Steve, Rosand, Jonathan, Rost, Natalia S., Markus, Hugh S., Traylor, Matthew, Lanfranconi, Silvia, Zhang, Cathy R., Cloonan, Lisa, Falcone, Guido J., Radmanesh, Farid, Fitzpatrick, Kaitlin, Kanakis, Allison

17q25 Locus is associated with white matter hyperintensity volume in ischemic stroke, but not with lacunar stroke status

- Adib-Samii, Poneh, Rost, Natalia, Gschwendtner, Andreas, Malik, Rainer, Richie, Alexa, Gamble, Dale, Segal, Helen, Parati, Eugenio A., Ciusani, Emilio, Holliday, Elizabeth G., Maguire, Jane, Wardlaw, Joanna, Traylor, Matthew, Worrall, Bradford, Bis, Joshua, Wiggins, Kerri L., Longstreth, Will, Kittner, Steve J., Cheng, Yu-Ching, Mosley, Thomas, Falcone, Guido J., Furie, Karen L., Leiva-Salinas, Carlos, Devan, William, Lau, Benison C., Saleem Khan, Muhammed, Australian Stroke Genetics Collaborative, Wellcome Trust Case-Control Consortium-2, METASTROKE, Sharma, Pankaj, Fornage, Miriam, Mitchell, Braxton D., Psaty, Bruce M., Sudlow, Cathie, Biffi, Alessandro, Levi, Christopher, Boncoraglio, Giorgio B., Rothwell, Peter M., Meschia, James, Dichgans, Martin, Rosand, Jonathan, Markus, Hugh S., Lanfranconi, Silvia, Fitzpatrick, Kaitlin, Bevan, Steve, Kanakis, Allison, Valant, Valerie

Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke

- Bellenguez, Céline, Bevan, Steve, Band, Gavin, Syme, Paul D., Malik, Rainer, Pera, Joanna, Norrving, Bo, Lemmens, Robin, Freeman, Colin, Schanz, Renata, James, Tom, Poole, Deborah, Gschwendtner, Andreas, Murphy, Lee, Segal, Helen, Cortellini, Lynelle, Cheng, Yu-Ching, Woo, Daniel, Nalls, Michael A., Müller-Myhsok, Bertram, Meisinger, Christa, Seedorf, Udo, Ross-Adams, Helen, Spencer, Chris C. A., Boonen, Steven, Wloch-Kopec, Dorota, Valant, Valerie, Slark, Julia, Furie, Karen, Delavaran, Hossein, Langford, Cordelia, Deloukas, Panos, Edkins, Sarah, Hunt, Sarah, Burgess, Annette I., Gray, Emma, Dronov, Serge, Peltonen, Leena, Gretarsdottir, Solveig, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Stefansson, Kari, Boncoraglio, Giorgio B., Parati, Eugenio A., Attia, John, Pirinen, Matti, Holliday, Elizabeth, Levi, Chris, Franzosi, Maria-Grazia, Goel, Anuj, Helgadottir, Anna, Blackwell, Jenefer M., Bramon, Elvira, Brown, Matthew A., Casas, Juan P., Corvin, Aiden, Jackson, Caroline A., Duncanson, Audrey, Jankowski, Janusz, Mathew, Christopher G., Palmer, Colin N. A., Plomin, Robert, Rautanen, Anna, Sawcer, Stephen J., Trembath, Richard C., Viswanathan, Ananth C., Wood, Nicholas W., Traylor, Matthew, Worrall, Bradford B., Kittner, Steven J., Mitchell, Braxton D., Kissela, Brett, Meschia, James F., Thijs, Vincent, Lindgren, Arne, Macleod, Mary Joan, Slowik, Agnieszka, Walters, Matthew, Strange, Amy, Rosand, Jonathan, Sharma, Pankaj, Farrall, Martin, Sudlow, Cathie L. M., Rothwell, Peter M., Dichgans, Martin, Donnelly, Peter, Markus, Hugh S., Su, Zhan

Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke

- Cole, John W., Xu, Huichun, Ryan, Kathleen, Jaworek, Thomas, Dueker, Nicole, McArdle, Patrick, Gaynor, Brady, Cheng, Yu-Ching, O'Connell, Jeffrey, Bevan, Steve, Malik, Rainer, Ahmed, Naveed Uddin, Amouyel, Philippe, Anjum, Sheraz, Bis, Joshua C., Crosslin, David, Danesh, John, Engelter, Stefan T., Fornage, Myriam, Frossard, Philippe, Holliday, Elizabeth, Levi, Christopher

Genetic overlap between diagnostic subtypes of ischemic stroke

- Holliday, Elizabeth G., Traylor, Matthew, Boncoraglio, Giorgio B., Clarke, Robert, Cole, John W., Fornage, Myriam, Furie, Karen L., Ikram, M. Arfan, Jannes, Jim, Kittner, Steven J., Lincz, Lisa F., Maguire, Jane M., Malik, Rainer, Oldmeadow, Christopher, Scott, Rodney J., Levi, Christopher, Attia, John, Bevan, Steve, Falcone, Guido, Hopewell, Jemma C., Cheng, Yu-Ching, Cotlarciuc, Ioana, Bis, Joshua C., Boerwinkle, Eric

Common variants at 6p21.1 are associated with large artery atherosclerotic stroke

- Holliday, Elizabeth G., Maguire, Jane M., Malik, Rainer, McEvoy, Mark, Biros, Erik, Lewis, Martin D., Lincz, Lisa F., Peel, Roseanne, Oldmeadow, Christopher, Smith, Wayne, Moscato, Pablo, Barlera, Simona, Evans, Tiffany-Jane, Bevan, Steve, Bis, Joshua C., Boerwinkle, Eric, Boncoraglio, Giorgio B., Brott, Thomas G., Scott, Rodney J., Levi, Christopher, Attia, John, Koblar, Simon A., Jannes, Jim, Sturm, Jonathan W., Hankey, Graeme J., Baker, Ross, Golledge, Jonathan, Parsons, Mark W.

Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12

- Kilarski, Laura L., Achterberg, Sefanja, Walters, Matthew, Worrall, Bradford B., Sale, Michele M., Algra, Ale, Kappelle, L. Jaap, Wijmenga, Cisca, Norrving, Bo, Sandling, Johanna K., Röennblom, Lars, Goris, An, Devan, William J., Franke, Andre, Sudlow, Cathie, Rothwell, Peter M., Levi, Christopher, Holliday, Elizabeth G., Fornage, Myriam, Psaty, Bruce, Gretarsdottir, Solveig, Thorsteinsdottir, Unnar, Seshadri, Sudha, Traylor, Matthew, Mitchell, Braxton D., Kittner, Steven, Clarke, Robert, Hopewell, Jemma C., Bis, Joshua C., Boncoraglio, Giorgio B., Meschia, James, Ikram, M. Arfan, Hansen, Bjorn M., Montaner, Joan, Malik, Rainer, Thorleifsson, Gudmar, Stefanson, Kari, Rosand, Jonathan, de Bakker, Paul I. W., Farrall, Martin, Dichgans, Martin, Markus, Hugh S., Bevan, Steve, Lindgren, Arne, Pare, Guillame, Sharma, Pankaj, Slowik, Agniescka, Thijs, Vincent

Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies

- Malik, Rainer, Bevan, Steve, de Stefano, Anita L., Fornage, Myriam, Psaty, Bruce M., Ikram, M. Afran, Launer, Lenore J., Van Duijn, Cornelia M., Sharma, Pankaj, Mitchell, Braxton D., Rosand, Jonathan, Meschia, James F., Nalls, Michael A., Levi, Christopher, Rothwell, Peter M., Sudlow, Cathie, Markus, Hugh S., Seshadri, Sudha, Dichgans, Martin, MD Wellcome Trust Case Control Consortium 2,, Holliday, Elizabeth G., Devan, William J., Cheng, Yu-Ching, Ibrahim-Verbaas, Carla A., Verhaaren, Benjamin F. J., Bis, Joshua C., Joon, Aron Y.

Common coding variant in SERPINA1 increases the risk for large artery stroke

- Malik, Rainer, Cardenas, IF, Rothwell, PM, Levi, C, Attia, J, Sudlow, CLM, Braun, D, Markus, HS, Wintrode, PL, Berger, K, Jenne, DE, Dichgans, M, Dau, Therese, Seixas, Susana, Bevan, Steve, Lincz, Lisa F., Holliday, Elizabeth G., Burgess, Annette I., Rannikmäe, Kristiina, Minnerup, Jens, Kriebel, Jennifer, Waldenberger, Melanie, Müller-Nurasyid, Martina, Gonik, Maria, Levi, Christopher, Attia, John, Maguire, Jane, Sivakumar, Anirudh, Deredge, Daniel J., Edeleva, Evgeniia V., Götzfried, Jessica, van der Laan, Sander W., Pasterkamp, Gerard, Beaufort, Nathalie

Low-frequency and common genetic variation in ischemic stroke: the METASTROKE collaboration

- Malik, Rainer, Traylor, Matthew, Battey, Thomas W. K., Berger, Klaus, Boncoraglio, Giorgio B., Chauhan, Ganesh, Cheng, Yu-Ching, Chen, Wei-Min, Clarke, Robert, Cotlarciuc, Ioana, Debette, Stephanie, Falcone, Guido J., Pulit, Sara L., Levi, Christopher R., Bevan, Steve, Hopewell, Jemma C., Holliday, Elizabeth G., Zhao, Wei, Abrantes, Patricia, Amouyel, Philippe, Attia, John R.

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

- Malik, Rainer, Chauhan, Ganesh, Anderson, Christopher D., Chong, Michael, Adams, Hieab H. H., Ago, Tetsuro, Almgren, Peter, Amouyel, Philippe, Ay, Hakan, Bartz, Traci M., Benavente, Oscar R., Bevan, Steve, Traylor, Matthew, Holliday, Elizabeth G., Attia, John, Levi, Christopher R., Carrera, C, Carty, CL, Chasman, DI, Chen, W-M, Cole, JW, Correa, A, Cotlarciuc, I, Sargurupremraj, Muralidharan, Cruchaga, C, Danesh, J, de Bakker, PIW, DeStefano, AL, Den Hoed, M, Duan, Q, Engelter, ST, Falcone, GJ, Gottesman, RF, Grewal, RP, Okada, Yukinori, Gudnason, V, Gustafsson, S, Haessler, J, Harris, TB, Hassan, A, Havulinna, AS, Heckbert, SR, Holliday, EG, Howard, G, Hsu, F-C, Mishra, Aniket, Hyacinth, HI, Ikram, MA, Ingelsson, E, Irvin, MR, Jian, X, Jiménez-Conde, J, Johnson, JA, Jukema, JW, Kanai, M, Keene, KL, Rutten-Jacobs, Loes, Kissela, BM, Kleindorfer, DO, Kooperberg, C, Kubo, M, Lange, LA, Langefeld, CD, Langenberg, C, Launer, LJ, Lee, J-M, Lemmens, R, Giese, Anne-Katrin, van der Laan, Sander W., Gretarsdottir, Solveig

Genetic imbalance is associated with functional outcome after Ischemic Stroke

- Pfeiffer, Dorothea, Chen, Bowang, Schlicht, Kristina, Ginsbach, Philip, Abboud, Sherine, Bersano, Anna, Bevan, Steve, Brandt, Tobias, Caso, Valeria, Debette, Stephanie, Erhart, Philipp, Freitag-Wolf, Sandra, Giacalone, Giacomo, Grau, Armin J., Hayani, Eyad, Jern, Christina, Jiménez-Conde, Jordi, Kloss, Manja, Krawczak, Michael, Lee, Jin-Moo, Maguire, Jane M.

Investigating the causal relationship of C-reactive protein with 32 complex somatic and psychiatric outcomes: a large-scale cross-consortium mendelian randomization study

- Prins, Bram P., Abbasi, Ali, Valdes, Ana M., Bras, Jose, Shatunov, Aleksey, Lu, Chen, Han, Buhm, Raychaudhuri, Soumya, Bevan, Steve, Mayes, Maureen D., Tsoi, Lam C., Evangelou, Evangelos, Wong, Anson, Nair, Rajan P., Grant, Stuan F. A., Polychronakos, Constantin, Radstake, Timothy R. D., van Heel, David A., Dunstan, Melanie L., Wood, Nicholas W., Al-Chalabi, Ammar, Dehghan, Abbas, Hakonarson, Hakon, Vaez, Ahmad, Markus, Hugh S., Elder, James T., Knight, Jo, Arking, Dan E., Spector, Timothy D., Koeleman, Bobby P. C., van Duijn, Cornelia M., Martin, Javier, Morris, Andrew P., Weersma, Rinse K., Nolte, Ilja, Wijmenga, Cisca, Munroe, Patricia B., Perry, John R. B., Pouget, Jennie G., Jamshidi, Yalda, Snieder, Harold, Alizadeh, Behrooz Z., Tooney, Paul, Franceschini, Nora, Stuart, Philip E., Guterriez Achury, Javier, Mistry, Vanisha, Bradfield, Jonathan P.

Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease

- Rannikmäe, Kristiina, Davies, Gail, Deka, Ranjan, Woo, Jessica G., Martin, Lisa J., Jimenez-Conde, Jordi, Selim, Magdy, Brown, Devin L., Silliman, Scott L., Kidwell, Chelsea S., Montaner, Joan, Langefeld, Carl D., Thomson, Pippa A., Holliday, Elizabeth G., Levi, Christopher R., Attia, John, Rothwell, Peter M., Poole, Deborah L., Bevan, Steve, Devan, William J., Falcone, Guido J., Traylor, Matthew, Anderson, Christopher D., Battey, Thomas W. K., Radmanesh, Farid

Common NOTCH3 variants and cerebral small-vessel disease

- Rutten-Jacobs, Loes C. A., Traylor, Matthew, Levi, Christopher, Rost, Natalia S., Rosand, Jonathan, Hassan, Ahamad, Markus, Hugh S., Adib-Samii, Poneh, Thijs, Vincent, Sudlow, Cathie, Rothwell, Peter M., Boncoraglio, Giorgio, Dichgans, Martin, Bevan, Steve, Meschia, James

Association of MTHFR C677T genotype with ischemic stroke is confined to cerebral small vessel disease subtype

- Rutten-Jacobs, Loes C. A., Traylor, Matthew, Levi, Christopher, Rost, Natalia S., Rosand, Jonathan, Hassan, Ahamad, Bevan, Steve, Markus, Hugh S., Adib-Samii, Ppneh, Thijs, Vincent, Sudlow, Cathie, Rothwell, Peter M., Boncoraglio, Giorgio, Dichgans, Martin, Meschia, James, Maguire, Jane

Genome-wide association meta-analysis of functional outcome after ischemic stroke

- Söderholm, Martin, Pedersen, Annie, Jood, Katarina, Lee, Jin-Moo, Lemmens, Robin, Levi, Christopher, Mitchell, Braxton D., Norrving, Bo, Rannikmäe, Kristiina, Rost, Natalia S., Rosand, Jonathan, Rothwell, Peter M., Lorentzen, Erik, Scott, Rodney, Strbian, Daniel, Sturm, Jonathan W., Sudlow, Cathie, Traylor, Matthew, Thijs, Vincent, Tatlisumak, Turgut, Woo, Daniel, Worrall, Bradford B., Maguire, Jane M., Stanne, Tara M., Lindgren, Arne, Jern, Christina, Bevan, Steve, Olsson, Maja, Cole, John W., Fernandez-Cadenas, Israel, Hankey, Graeme J., Jimenez-Conde, Jordi

A novel MMP12 locus Is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach

- Traylor, Matthew, Mäkelä, Kari-Matti, Malik, Rainer, Sudlow, Cathie, Bevan, Steve, Raitoharju, Emma, Oksala, Niku, Thijs, Vincent, Lemmens, Robin, Lindgren, Arne, Slowik, Agnieszka, Kilarski, Laura L., Maguire, Jane M., Walters, Matthew, Algra, Ale, Sharma, Pankaj, Attia, John R., Boncoraglio, Giorgio B., Rothwell, Peter M., de Bakker, Paul I. W., Bis, Joshua C., Saleheen, Danish, Holliday, ELizabeth G., Kittner, Steven J., Mitchell, Braxton D., Rosand, Jonathan, Meschia, James F., Levi, Christopher, Dichgans, Martin, Lehtimäki, Terho, Lewis, Cathryn M., Markus, Hugh S., Devan, William J., Nalls, Mike A., Wiggins, Kerri L., Zhao, Wei, Cheng, Yu-Ching, Achterberg, Sefanja

Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke

- Traylor, Matthew, Zhang, Cathy R., Fitzpatrick, Kaitlin, Kanakis, Allison, Barrick, Thomas R., Moynihan, Barry, Lewis, Cathryn M., Boncoraglio, Giorgio B., Lemmens, Robin, Thijs, Vincent, Sudlow, Cathie, Wardlaw, Joanna, Adib-Samii, Poneh, Levi, Christopher, Bevan, Steve, Devan, William J., Parsons, Owen E., Lanfranconi, Silvia, Gregory, Sarah, Cloonan, Lisa, Falcone, Guido J., Radmanesh, Fadrid