Differential cell counts using center-point networks achieves human-level accuracy and efficiency over segmentation
- Creator: Lee, Sandra M. W. , Shaw, Andrew , Simpson, Jodie L. , Uminsky, David , Garratt, Luke W.
- Resource Type: journal article
- Date: 2021
Endoplasmic reticulum-unfolded protein response signalling is altered in severe eosinophilic and neutrophilic asthma
- Creator: Pathinayake, Prabuddha S. , Waters, David W. , Gibson, Peter G. , Hansbro, Philip M. , Wark, Peter A. B. , Nichol, Kristy S. , Brown, Alexandra C. , Reid, Andrew T. , Hsu, Alan Chen-Yu , Horvat, Jay C. , Wood, Lisa G. , Baines, Katherine J. , Simpson, Jodie L.
- Resource Type: journal article
- Date: 2021
Hemopexin: a novel anti-inflammatory marker for distinguishing COPD from asthma
- Creator: Winter, Natasha A. , Gibson, Peter G. , Fricker, Michael , Simpson, Jodie L. , Wark, Peter A. , McDonald, Vaness M.
- Resource Type: journal article
- Date: 2021
Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial
- Creator: Ramakrishnan, Sanjay , Nicolau, Dan V. , Bright, Stephen , Butler, Christopher , Cane, Jennifer L. , Halner, Andreas , Matthews, Philippa C. , Donnelly, Louise E. , Simpson, Jodie L. , Baker, Jonathan R. , Fadai, Nabil T. , Peterson, Stefan , Langford, Beverly , Bengtsson, Thomas , Barnes, PJ , Russell, REK , Bafadhel, M , Mahdi, Mahdi , Jeffers, Helen , Mwasuku, Christine , Krassowska, Karolina , Fox, Robin , Binnian, Ian , Glover, Victoria
- Resource Type: journal article
- Date: 2021
Molecular markers of type 2 airway inflammation are similar between eosinophilic severe asthma and eosinophilic chronic obstructive pulmonary disease
- Creator: Fricker, Michael , McDonald, Vanessa M. , Winter, Natasha A. , Baines, Katherine J. , Wark, Peter A. B. , Simpson, Jodie L. , Gibson, Peter G.
- Resource Type: journal article
- Date: 2021
Neutrophil extracellular traps, disease severity, and antibiotic response in bronchiectasis: an international, observational, multicohort study
- Creator: Keir, Holly R. , Shoemark, Amelia , Cant, Erin , Einarsson, Gisli G. , Furrie, Elizabeth , Elborn, J. Stuart , Fong, Christopher J. , Finch, Simon , Rogers, Geraint B. , Blasi, Francesco , Sibila, Oriol , Aliberti, Stefano , Dicker, Alison J. , Simpson, Jodie L. , Huang, Jeffrey T. J. , Chalmers, James D. , Perea, Lidia , Pollock, Jennifer , Giam, Yan Hui , Suarez-Cuartin, Guillermo , Crichton, Megan L. , Lonergan, Mike , Oriano, Martina
- Resource Type: journal article
- Date: 2021
Neutrophilic asthma features increased airway classical monocytes
- Creator: Niessen, Natalie M. , Baines, Katherine J. , Simpson, Jodie L. , Scott, Hayley A. , Qin, Ling , Gibson, Peter G. , Fricker, Michael
- Resource Type: journal article
- Date: 2021
Neutrophils in asthma: The good, the bad and the bacteria
- Creator: Crisford, Helena , Sapey, Elizabeth , Rogers, Geraint B. , Taylor, Steven , Nagakumar, Prasad , Lokwani, Ravi , Simpson, Jodie L.
- Resource Type: journal article
- Date: 2021
Outcomes of protracted bacterial bronchitis in children: A 5-year prospective cohort study
- Creator: Ruffles, Tom J.C. , Marchant, Julie M. , Masters, Ian B. , Yerkovich, Stephanie T. , Wurzel, Danielle F. , Gibson, Peter G. , Busch, Greta , Baines, Katherine J. , Simpson, Jodie L. , Smith-Vaughan, Heidi C. , Pizzutto, Susan J. , Buntain, Helen M. , Hodge, Gregory , Hodge, Sandra , Upham, John W. , Chang, Anne B.
- Resource Type: journal article
- Date: 2021
Sputum TNF markers are increased in neutrophilic and severe asthma and are reduced by azithromycin treatment
- Creator: Niessen, Natalie M. , Gibson, Peter G. , Peters, Matthew J. , Marks, Guy B. , Baraket, Melissaa , Simpson, Jodie L. , Fricker, Michael , Baines, Katherine J. , Barker, Daniel , Yang, Ian A. , Upham, John W. , Reynolds, Paul N. , Hodge, Sandra , James, Alan L. , Jenkins, Christine
- Resource Type: journal article
- Date: 2021
The cost-effectiveness of azithromycin in reducing exacerbations in uncontrolled asthma
- Creator: O'Neill, Ciaran , Gibson, Peter G. , Heaney, Liam G. , Upham, John W. , Yang, Ian A. , Reynolds, Paul N. , Hodge, Sandra , Jenkins, Christine R. , Peters, Matthew , Marks, Guy B. , James, Alan L. , Simpson, Jodie L.
- Resource Type: journal article
- Date: 2021
The influence of early-life microbial exposures on long-term respiratory health
- Creator: Taylor, Steven L. , Simpson, Jodie L. , Rogers, Geraint B.
- Resource Type: journal article
- Date: 2021
Transcriptomics of biopsies identifies novel genes and pathways linked to neutrophilic inflammation in severe asthma
- Creator: Sánchez-Ovando, Stephany , Simpson, Jodie L. , Barker, Daniel , Baines, Katherine J. , Wark, Peter A. B.
- Resource Type: journal article
- Date: 2021
An altered sputum macrophage transcriptome contributes to the neutrophilic asthma endotype
- Creator: Fricker, Michael , Qin, Ling , Chung, Kian Fan , Gibson, Peter G. , Sánchez-Ovando, Stephany , Simpson, Jodie L. , Baines, Katherine J. , Riveros, Carlos , Scott, Hayley A. , Wood, Lisa G. , Wark, Peter A. B. , Kermani, Nazanin Z.
- Resource Type: journal article
- Date: 2022
Early Th2 inflammation in the upper respiratory mucosa as a predictor of severe COVID-19 and modulation by early treatment with inhaled corticosteroids: a mechanistic analysis
- Creator: Baker, Jonathan R. , Mahdi, Mahdi , Nicolau, Dan V. , Ramakrishnan, Sanjay , Barnes, Peter J. , Simpson, Jodie L. , Cass, Steven P. , Russell, Richard E. K. , Donnelly, Louise E. , Bafadhel, Mona
- Resource Type: journal article
- Date: 2022
Patterns of azithromycin use in obstructive airway diseases: a real-world observational study
- Creator: Thomas, Dennis , McDonald, Vanessa M. , Simpson, Jodie L. , Smith, Amber , Gupta, Sachin , Majellano, Eleanor , Gibson, Peter G.
- Resource Type: journal article
- Date: 2022
Rothia mucilaginosa is an anti-inflammatory bacterium in the respiratory tract of patients with chronic lung disease
- Creator: Rigauts, Charlotte , Aizawa, Juliana , Dondelinger, Yves , Vereecke, Lars , Van Acker, Heleen , Simpson, Jodie L. , Burr, Lucy , Willems, Anne , Tunney, Michael M. , Cigana, Cristina , Bragonzi, Alessandra , Coenye, Tom , Taylor, Steven L. , Crabbé, Aurelie , Rogers, Geraint B. , Govaerts, Matthias , Cos, Paul , Ostyn, Lisa , Sims, Sarah , Vandeplassche, Eva , Sze, Mozes
- Resource Type: journal article
- Date: 2022
Randomised controlled trial for the titration of oral corticosteroids using markers of inflammation in severe asthma
- Creator: Ramsahai, J. Michael , Simpson, Jodie L. , Cook, Alistair , Gibson, Peter G. , McDonald, Vanessa , Grainge, Christopher , Heaney, Liam G. , Wark, Peter A. B.
- Resource Type: journal article
- Date: 2023
Severity of Lung Function Impairment Drives Transcriptional Phenotypes of COPD and Relates to Immune and Metabolic Processes
- Creator: Negewo, Netsanet A. , Gibson, Peter G. , Simpson, Jodie L. , McDonald, Vanessa M. , Baines, Katherine J.
- Resource Type: journal article
- Date: 2023