Loss of the stress sensor GADD45A promotes stem cell activity and ferroptosis resistance in LGR4/HOXA9-dependent AML
- Creator: Hassan, Nunki , Yi, Hangyu , Carter, Daniel R. , Cheung, Belamy B. , Norris, Murray , Haber, Michelle , Kavallaris, Maria , Marshall, Glenn M. , Zhang, Xu Dong , Liu, Tao , Wang, Jianlong , Liebermann, Dan A. , Malik, Bilal , D'Andrea, RJ , Wang, JY , Gaspard-Boulinc, Lucie , Samaraweera, Saumya E. , Casolari, Debora A. , Seneviratne, Janith , Balachandran, Anushree , Chew, Tracy , Duly, Alastair
- Resource Type: journal article
- Date: 2024
Loss of PI(4,5)P₂ 5-phosphatase A contributes to resistance of human melanoma cells to RAF/MEK inhibitors
- Creator: Ye, Yan , Li, Qun , Wang, Lai Hu , Tseng, Hsin-Yi , Jin, Lei , Zhang, Xu Dong , Zhang, Lin Jie , Yang, Sen
- Resource Type: journal article
- Date: 2013
lncRNA TRMP-S directs dual mechanisms to regulate p27-mediated cellular senescence
- Creator: Shuai, Tian , Khan, Muhammad Riaz , Zhang, Xu Dong , Li, Jingmin , Thorne, Rick Francis , Wu, Mian , Shao, Fengmin
- Resource Type: journal article
- Date: 2021
LncRNA REG1CP promotes tumorigenesis through an enhancer complex to recruit FANCJ helicase for REG3A transcription
- Creator: Yari, Hamed , Jin, Lei , Teng, Liu , Wang, Yufang , Wu, Yongyan , Liu, Guang Zhi , Gao, Wei , Liang, Jin , Xi, Yanfeng , Feng, Yu Chen , Zhang, Chunming , Zhang, Yuan Yuan , Tabatabaee, Hessam , La, Ting , Yang, Rui Hong , Wang, Fu Hua , Yan, Xu Guang , Farrelly, Margaret , Scott, Rodney , Liu, Tao , Thorne, Rick F. , Guo, Su Tang , Zhang, Xu Dong
- Resource Type: journal article
- Date: 2019
LncRNA MILIP links YBX1 to translational activation of Snai1 and promotes metastasis in clear cell renal cell carcinoma
- Creator: Wang, Yanliang , Feng, Yu Chen , Zhang, Lina , Wang, Limeng , Thorne, Rick F. , Zhang, Xu Dong , Cao, Huixia , Shao, Feng-Min , Gan, Yujin , Teng, Liu , Wang, Li , La, Ting , Wang, Peilin , Gu, Yue , Yan, Lei , Li, Na
- Resource Type: journal article
- Date: 2022
LncRNA LIMp27 Regulates the DNA Damage Response through p27 in p53-Defective Cancer Cells
- Creator: La, Ting , Chen, Song , Jamaluddin, Muhammad Fairuz , Feng, Yu Chen , Tang, Hai Jie , Wang, Yanliang , Xu, Qin , Gu, Yue , Cao, Huixia , Liu, Tao , Thorne, Rick F. , Shao, Feng-Min , Zhao, Xiao Hong , Zhang, Xu Dong , Jin, Lei , Zhou, Shuai , Xu, Ran , Teng, Liu , Zhang, Yuan Yuan , Ye, Kaihong , Xu, Liang , Guo, Tao
- Resource Type: journal article
- Date: 2023
LncRNA IDH1-AS1 links the functions of c-Myc and HIF1a via IDH1 to regulate the Warburg effect
- Creator: Xiang, Shaoxun , Gu, Hao , Jin, Lei , Thorne, Rick F. , Zhang, Xu Dong , Wu, Mian
- Resource Type: journal article
- Date: 2018
LncRNA GUARDIN suppresses cellular senescence through a LRP130-PGC1α-FOXO4-p21-dependent signaling axis
- Creator: Sun, Xuedan , Thorne, Rick Francis , Zhang, Xu Dong , He, Miao , Li, Jinming , Feng, Shanshan , Liu, Xiaoying , Wu, Mian
- Resource Type: journal article
- Date: 2020
LncRNA GIRGL drives CAPRIN1-mediated phase separation to suppress glutaminase-1 translation under glutamine deprivation
- Creator: Wang, Ruijie , Cao, Leixi , Thorne, Rick Francis , Zhang, Xu Dong , Li, Jinming , Shao, Fengmin , Zhang, Lirong , Wu, Mian
- Resource Type: journal article
- Date: 2021
LINC01559 promotes lung adenocarcinoma metastasis by disrupting the ubiquitination of vimentin
- Creator: Feng, Hao , Xu, Dengfei , Jiang, Chenyang , Chen, Yuming , Wang, Junru , Ren, Zirui , Li, Xiang , Zhang, Xu Dong , Cang, Shundong
- Resource Type: journal article
- Date: 2024
Lactate dehydrogenase 5 expression in melanoma increases with disease progression and is associated with expression of Bcl-XL and Mcl-1, but not Bcl-2 proteins
- Creator: Zhuang, Liquing , Scolyer, Richard A. , Murali, Rajmohan , McCarthy, Stanley W. , Zhang, Xu Dong , Thompson, John F. , Hersey, Peter
- Resource Type: journal article
- Date: 2010
KMT2A and chronic inflammation as potential drivers of sporadic parathyroid adenoma
- Creator: Xu, Qin , La, Ting , Shao, Zehua , Zhang, Yuan Yuan , Zhao, Xiao Hong , Feng, Yu Chen , Jin, Lei , Baker, Mark , Thorne, Rrick F. , Zhang, Xu Dong , Shao, Feng-Min , Cao, Huixia , Ye, Kaihong , Wang, Li , Wang, Shasha , Hu, Yifeng , Teng, Liu , Yan, Lei , Li, Jinming , Zhang, Zhenhua
- Resource Type: journal article
- Date: 2024
KDM6A promotes imatinib resistance through YY1-mediated transcriptional upregulation of TRKA independently of its demethylase activity in chronic myelogenous leukemia
- Creator: Zhang, Chengwan , Shen, Li , Wei, Dongping , Thorne, Rick F. , Zhang, Xu Dong , Yu, Liang , Chen, Song , Zhu, Yifu , Xu, Ran , Deng, Zhikui , Liu, Xiaoning , Ding, Yihan , Wang, Chunling , Shi, Yuye , Bei, Liye
- Resource Type: journal article
- Date: 2021
Involvement of vacuolar H⁺₋ATPase in killing of human melanoma cells by the sphingosine kinase analogue FTY720
- Creator: Tay, Kwang Hong , Liu, Xiaoying , Chi, Mengna , Jin, Lei , Jiang, Chen Chen , Guo, Su Tang , Verrills, Nicole M. , Tseng, Hsin-Yi , Zhang, Xu Dong
- Resource Type: journal article
- Date: 2015
Involvement of endoplasmic reticulum stress in docetaxel-induced JNK-dependent apoptosis of human melanoma
- Creator: Mhaidat, Nizar M. , Thorne, Rick , Zhang, Xu Dong , Hersey, Peter
- Resource Type: journal article
- Date: 2008
Insulin induces drug resistance in melanoma through activation of the PI3K/Akt pathway
- Creator: Chi, Mengna , Ye, Yan , Zhang, Xu Dong , Chen, Jiezhong
- Resource Type: journal article
- Date: 2014
INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas
- Creator: Chi, Meng Na , Guo, Su Tang , Croft, Amanda , Hondermarck, Hubert , Scolyer, Richard A. , Jiang, Chen Chen , Zhang, Xu Dong , Wilmott, James S. , Guo, Xiang Yun , Yan, Xu Guang , Wang, Chun Yan , Liu, Xiao Ying , Jin, Lei , Tseng, Hsin-Yi , Liu, Tao
- Resource Type: journal article
- Date: 2015
Inhibition of MEK blocks GRP78 up-regulation and enhances apoptosis induced by ER stress in gastric cancer cells
- Creator: Zhang, Lin Jie , Chen, Si , Wu, Pin , Hu, Chun Song , Thorne, Rick F. , Luo, Chang Ming , Hersey, Peter , Zhang, Xu Dong
- Resource Type: journal article
- Date: 2009
Inhibition of HSP90 by AUY922 preferentially kills mutant KRAS colon cancer cells by activating Bim through ER stress
- Creator: Wang, Chun Yan , Guo, Su Tang , Wang, Jia Yu , Liu, Fen , Zhang, Yuan Yuan , Yari, Hamed , Yan, Xu Guang , Jin, Lei , Zhang, Xu Dong , Jiang, Chen Chen
- Resource Type: journal article
- Date: 2016
Inhibition of endoplasmic reticulum stress-induced apoptosis of melanoma cells by the ARC protein
- Creator: Chen, Li Hua , Jiang, Chen Chen , Watts, Ralph , Thorne, Rick F. , Kiejda, Kelly A. , Zhang, Xu Dong , Hersey, Peter
- Resource Type: journal article
- Date: 2008