Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors
- Creator: Smith, Amanda M. , Dun, Matthew D. , Toop, Hamish , Lock, Richard B. , Powell, Jason A. , Thomas, Daniel , Guthridge, Mark A. , Moore, Andrew , Ashman, Leonie K. , Skelding, Kathryn A. , Enjeti, Anoop , Verrills, Nicole M. , Lee, Erwin M. , Harrison, Celeste , Kahl, Richard , Flanagan, Hayley , Panicker, Nikita , Mashkani, Baratali , Don, Anthony S. , Morris, Jonathan
- Resource Type: journal article
- Date: 2016
Altered protein phosphatase 2A methylation and Tau phosphorylation in the young and aged brain of methylenetetrahydrofolate reductase (MTHFR) deficient mice
- Creator: Sontag, Jean-Marie , Wasek, Brandi , Taleski, Goce , Smith, Josephine , Arning, Erland , Sontag, Estelle , Bottiglieri, T
- Resource Type: journal article
- Date: 2014
Basal protein phosphatase 2A activity restrains cytokine expression: role for MAPKs and tristetraprolin
- Creator: Rahman, Md. Mostafizur , Rumzhum, Nowshin N. , Morris, Jonathan C. , Clark, Andrew R. , Verrills, Nicole M. , Ammit, Alaina J.
- Resource Type: journal article
- Date: 2015
Functional importance of PP2A regulatory subunit loss in breast cancer
- Creator: Watt, Lauren F. , Panicker, Nikita , Mannan, Abdul , Copeland, Ben , Kahl, Richard G. S. , Dun, Matthew D. , Young, Barbara , Roselli, Severine , Verrills, Nicole M.
- Resource Type: journal article
- Date: 2017
Functional role of protein phosphatase 2A and its regulatory subunit B55α in development and breast cancer
- Creator: Panicker, Nikita
- Resource Type: thesis
- Date: 2022
Heterocyclic substituted cantharidin and norcantharidin analogues-synthesis, protein phosphatase (1 and 2A) inhibition, and anti-cancer activity
- Creator: Hill, Timothy A. , Stewart, Scott G. , Sauer, Benjamin , Gilbert, Jayne , Ackland, Stephen P. , Sakoff, Jennette A. , McCluskey, Adam
- Resource Type: journal article
- Date: 2007
Immunoregulatory therapies for inflammatory diseases
- Creator: Monogar, Prema Mono Nair
- Resource Type: thesis
- Date: 2016
Leucine carboxyl methyltransferase 1 (LCMT1)-dependent methylation regulates the association of protein phosphatase 2A and Tau protein with plasma membrane microdomains in neuroblastoma cells
- Creator: Sontag, Jean-Marie , Nunbhakdi-Craig, Viyada , Sontag, Estelle
- Resource Type: journal article
- Date: 2013
Mast cell function: regulation of degranulation by serine/threonine phosphatases
- Creator: Sim, Alistair T. R. , Ludowyke, Russell I. , Verrills, Nicole M.
- Resource Type: journal article
- Date: 2006
Methyl donor supplementation reduces phospho-Tau, Fyn and demethylated protein phosphatase 2A levels and mitigates learning and motor deficits in a mouse model of tauopathy
- Creator: van Hummel, Annika , Taleski, Goce , Sontag, Jean-Marie , Feiten, Astrid Feentje , Ke, Yazi D. , Ittner, Lars M. , Sontag, Estelle
- Resource Type: journal article
- Date: 2023
Modified norcantharidins: synthesis, protein phosphatases 1 and 2A inhibition, and anticancer activity
- Creator: Hart, Matthew E. , Chamberlin, A. Richard , Walkom, Cecilia , Sakoff, Jennette A. , McCluskey, Adam
- Resource Type: journal article
- Date: 2004
Novel insights into protein phosphatase 2A regulation and function in cell adhesion
- Creator: Schuhmacher, Diana
- Resource Type: thesis
- Date: 2022
PP2A phosphatase suppresses function of the mesenchymal invasion regulator NEDD9
- Creator: Bradbury, Peta , Mahmassani, Maha , Zhong, Jessie , Turner, Kylie , Paul, Andre , Verrills, Nicole M. , O'Neill, Geraldine M.
- Resource Type: journal article
- Date: 2012
Ppp2r2aKnockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55 alpha, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development
- Creator: Panicker, Nikita , Coutman, Melody , Lawlor-O'Neill, Charley , Kahl, Richard G. S. , Roselli, Severine , Verrills, Nicole M.
- Resource Type: journal article
- Date: 2020
Protein phosphatase 2A (PP2A): a key phosphatase in the progression of chronic obstructive pulmonary disease (COPD) to lung cancer
- Creator: Nader, Cassandra P. , Cidem, Aylin , Verrills, Nicole M. , Ammit, Alaina J.
- Resource Type: journal article
- Date: 2019
Protein phosphatase 2A and tau: an orchestrated 'Pas de Deux'
- Creator: Taleski, Goce , Sontag, Estelle
- Resource Type: journal article
- Date: 2018
Protein phosphatase 2A carboxymethylation and regulatory B subunits differentially regulate mast cell degranulation
- Creator: Kranias, Gregory , Watt, Lauren F. , Carpenter, Helen , Holst, Jeff , Ludowyke, Russell , Strack, Stefan , Sim, Alistair T. R. , Verrills, Nicole M.
- Resource Type: journal article
- Date: 2010
Protein phosphatase 2A: more than a passenger in the regulation of epithelial cell-cell junctions
- Creator: Schuhmacher, Diana , Sontag, Jean-Marie , Sontag, Estelle
- Resource Type: journal article
- Date: 2019
Regulation of the tumour suppressor PP2A by oncogenic tyrosine kinases
- Creator: Roberts, Kathryn
- Resource Type: thesis
- Date: 2010
Serine/threonine protein phosphatase inhibition enhances the effect of thymidylate synthase inhibition
- Creator: Sakoff, Jennette A. , Howitt, Ian J. , Ackland, Stephen P. , McCluskey, Adam
- Resource Type: journal article
- Date: 2004