PI(4,5)P2 5-phosphatase A regulates PI3K/Akt signalling and has a tumour suppressive role in human melanoma
- Creator: Ye, Yan , Jin, Lei , Tay, Kwang Hong , Tseng, Hsin-Yi , Guo, Su Tang , de Bock, Charles E. , Jiang, Chen Chen , Wang, Chun Yang , Wu, Mian , Zhang, Lie Jie , Hersey, Peter , Scolyer, Richard A. , Wilmott, James S. , Zhang, Xu Dong , Hu, Wang Lai , Yosufi, Benafsha , Thorne, Rick F. , Liu, Tao , Rizos, Helen , Yan, Xu Guang , Dong, Li
- Resource Type: journal article
- Date: 2013
Diminished hERG K+ channel activity facilitates strong human labour contractions but is dysregulated in obese women
- Creator: Parkington, Helena C. , Stevenson, Janet , Tonta, Mary A. , Paul, Jonathan , Butler, Trent , Maiti, Kaushik , Chan, Eng-Cheng , Sheehan, Penelope M. , Brennecke, Shaun P. , Coleman, Harold A. , Smith, Roger
- Resource Type: journal article
- Date: 2014
Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process
- Creator: Springelkamp, Henriët , Höhn, René , Luo, Xiaoyan , Deloukas, Panos , Duncanson, Audrey , Jankowski, Janusz , Markus, Hugh S. , Mathew, Christopher G. , Palmer, Colin N. A. , Plomin, Robert , Rautanen, Anna , Sawcer, Stephen J. , Trembath, Richard C. , Ramdas, Wishal D. , Viswanathan, Ananth C. , Wood, Nicholas W. , Spencer, Chris C. A. , Band, Gavin , Bellenguez, Céline , Freeman, Colin , Hellenthal, Garrett , Giannoulatou, Eleni , Pirinen, Matti , Pearson, Richard , Vithana, Eranga , Strange, Amy , Su, Zhan , Vukcevic, Damjan , Donnelly, Peter , Langford, Cordelia , Hunt, Sarah E. , Edkins, Sarah , Gwilliam, Rhian , Blackburn, Hannah , Bumpstead, Suzannah J. , Nongpiur, Monisha E. , Droniv, Serge , Gillman, Matthew , Gray, Emma , Hammond, Naomi , Jayakumar, Alagurevathi , McCann, Owen T. , Liddle, Jennifer , Potter, Simon C. , Ravindrarajah, Alagurevathi , Rocketts, Michelle , Montgomery, Grant W. , Waller, Matthew , Weston, Paul , Widaa, Sara , Whittaker, Pamela , Barroso, Ines , Blackwell, Jenefer M. , Brown , Matthew A. , Corvin, Aiden , Xu, Liang , Spencer , Chris C. A. , Spector, Timothy D. , Mirshahi, Alireza , Saw, Seang-Mei , Vingerling, Johannes R. , Teo, Yik-Ying , Haines, Jonathan L. , Wolfs, Roger C. W. , Lemij, Hans G. , Tai, E-Shyong , Mountain, Jenny E. , Jansonius, Nomdo M. , Jonas, Jost B. , Hammond, CJ , Gharahkhani, Puya , Lu, Yi , Amin, Najaf , Mishra, Aniket , Karssen, Lennart C. , Sim, Kar-seng , van Leeuwen, Elisabeth M. , Iglesias, Adriana I. , Verhoeven, Virginie J. M. , Hauser, Michael A. , Loon, Seng-Chee , Despriet, Dominiek D. G. , Nag, Abhishek , Venturini, Cristina , Hysi, Pirro G. , Sanfilippo, Paul G. , Schillert, Arne , Kang, Jae H. , Landers, John , Jonasson, Fridbert , Cree, Angela J. , van Koolwijk, Leonieke M. E. , Rivadeneira, Fernando , Souzeau, Emmanuelle , Jonsson, Vesteinn , Khor, Chiea-Cheun , Menon, Geeta , Mitchell, Paul , Wang, Jie Jin , Rochtchina, Elena , Attia, John , Scott, Rodney , Holliday, Elizabeth G. , Wong, Tien-Yin , Baird, Paul N. , Xie, Jing , Loomis, Stephanie J. , Inouye, Michael , Viswanathan, Ananth , Sim, Xueling , Weinreb, Robert N. , de Jong, Paulus T. V. M. , Oostra, Ben A. , Uitterlinden, André G. , Hofman, Albert , Ennis, Sarah , Thorsteinsdottir, Unnu , Bailey, Jessica N. Cooke , Burdon, Kathryn , Allingham, R. Band , Brilliant, Murray H. , Budenz, Donald L. , Christen, William G. , Fingert, John , Friedman, David S. , Gaasterland, Douglas , Gaasterland, Terry , Gibson, Jane , Hauder, Michael A. , Kang, Jae Hee , Kraft, Peter , Lee, Richard K. , Lichter, Paul R. , Liu, Yutao , Moroi, Sayoko E. , Pasquale, Louis R. , Thorleifsson, Gudmar , Pericak-Vance, Margaret A. , Realini, Anthony , Richards, Julia E. , Schuman, Joel S. , Scott, William K. , Singh, Kuldev , Sit, Arthur J. , Vollrath, Douglas , Wiggs, Janey L. , Janssen, Sarah F. , Wollstein, Gadi , Zack, Donald J. , Zhang, Kang , Bramon, Elvira , Brown, Matthew A. , Casas, Juan P.
- Resource Type: journal article
- Date: 2014
Non-canonical function of spindle assembly checkpoint proteins after APC activation reduces aneuploidy in mouse oocytes
- Creator: Lane, Simon I. R. , Jones, Keith T.
- Resource Type: journal article
- Date: 2014
Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites
- Creator: Thorburn, Alison N. , McKenzie, Craig I. , Chevalier, Nina , Tan, Jian K. , Marinõ, Eliana , Moore, Rob J. , Wong, Lee , McConville, Malcolm J. , Tull, Dedreia L. , Wood, Lisa G. , Murphy, Vanessa E. , Mattes, Joerg , Shen, Sj , Gibson, Peter G. , MacKay, Charles R. , Stanley, Dragana , MacIa, Laurence , Mason, Linda J. , Roberts, Laura K. , Wong, Connie H. Y. , Shim, Raymond , Robert, Remy
- Resource Type: journal article
- Date: 2015
Methylome sequencing in triple-negative breast cancer reveals distinct methylation clusters with prognostic value
- Creator: Stirzaker, Clare , Zotenko, Elena , Avery-Kiejda, Kelly A. , Peters, Kate M. , French, Juliet D. , Stein, Sandra , Korbie, Darren J. , Trau, Matt , Forbes, John F. , Scott, Rodney J. , Brown, Melissa A. , Francis, Glenn D. , Song, Jenny Z. , Clark, Susan J. , Qu, Wenjia , Nair, Shalima S. , Locke, Warwick J. , Stone, Andrew , Armstong, Nicole J. , Robinson, Mark D. , Dobrovic, Alexander
- Resource Type: journal article
- Date: 2015
North Atlantic storm track changes during the Last Glacial Maximum recorded by alpine speleothems
- Creator: Luetscher, Marc , Boch, R. , Sodeman, H. , Spötl, C. , Cheng, H. , Edwards, R. L. , Frisia, S. , Hof, F. , Muller, W.
- Resource Type: journal article
- Date: 2015
Paracingulate sulcus morphology is associated with hallucinations in the human brain
- Creator: Garrison, Jane R. , Fernyhough, Charles , Catts, Stanley , Henskens, Frans , Pantelis, Christos , Loughland, Carmel , Simons, Jon S. , McCarthy-Jones, Simon , Haggard, Mark , Carr, Vaughan , Schall, Ulrich , Scott, Rodney , Jablensky, Assen , Mowry, Bryan , Michie, Patricia
- Resource Type: journal article
- Date: 2015
Synaptic NMDA receptor activity is coupled to the transcriptional control of the glutathione system
- Creator: Baxter, Paul S. , Bell, Karen F. S. , Hasel, Philip , Kaindl, Angela M. , Fricker, Michael , Thomson, Derek , Cregan, Sean P. , Gillingwater, Thomas H. , Hardingham, Giles E.
- Resource Type: journal article
- Date: 2015
A variant at 9p21.3 functionally implicates CDKN2B in paediatric B-cell precursor acute lymphoblastic leukaemia aetiology.
- Creator: Hungate, Eric A. , Vora, Sapana R. , Rudant, Jéremie , Orsi, Laurent , Clavel, Jacqueline , Milne, Elizabeth , Scott, Rodney J. , Pui, Ching-Hon , Cox, Nancy J. , Loh, Mignon L. , Yang, Jun J. , Skol, Andrew D. , Gamazon, Eric R. , Onel, Kenan , Moriyama, Takaya , Best, Timothy , Hulur, Imge , Lee, Younghee , Evans, Tiffany-Jane , Ellinghaus, Eva , Stanulla, Martin
- Resource Type: journal article
- Date: 2016
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function
- Creator: Pattaro, Cristian , Teumer, Alexander , Taliun, Daniel , Wallaschofski, Henri , Vöelzke, Henry , Brenner, Hermann , Kroemer, Heyo K. , Kramer, Holly , Lin, Honghuang , Leach, I. Mateo , Ford, Ian , Guessous, Idris , Rudan, Igor , Olden, Matthias , Prokopenko, Inga , Borecki, Ingrid , Heid, Iris M. , Kolcic, Ivana , Persico, Ivana , Jukema, J. Wouter , Wilson, James F. , Felix, Janine F. , Divers, Jasmin , Lambert, Jean-Charles , Foster, Meredith , Stafford, Jeanette M. , Gaspoz, Jean-Michel , Smith, Jennifer A. , Faul, Jessica D. , Wang, Jie Jin , Ding, Jingzhong , Hirschhorn, Joel N. , Attia, John , Whitfield, John B. , Chalmers, John , Yang, Qiong , Viikari, Jorma , Coresh, Josef , Denny, Joshua C. , Karjalainen, Juha , Fernandes, Jyotika K. , Endlich, Karlhans , Butterbach, Katja , Keene, Keith L. , Lohman, Kurt , Portas, Laura , Chen, Ming-Huei , Launer, Lenore J. , Lyytikäinen, Leo-Pekka , Yengo, Loic , Franke, Lude , Ferrucci, Luigi , Rose, Lynda M. , Kedenko, Lyudmyla , Rao, Madhumathi , Struchalin, Maksim , Kleber, Marcus E. , Pers, Tune H. , Cavalieri, Margherita , Haun, Margot , Cornelis, Marilyn C. , Ciullo, Marina , Pirastu, Mario , de Andrade, Mariza , McEvoy, Mark A. , Woodward, Mark , Adam, Martin , Cocca, Massimiliano , Johnson, Andrew D. , Nauck, Matthias , Imboden, Medea , Waldenberger, Melanie , Pruijm, Menno , Metzger, Marie , Stumvoll, Michael , Evans, Michele K. , Sale, Michele M. , Käehöenen, Mika , Boban, Mladen , Ko, Yi-An , Bochud, Murielle , Rheinberger, Myriam , Verweij, Niek , Bouatia-Naji, Nabila , Martin, Nicholas G. , Hastie, Nick , Probst-Hensch, Nicole , Soranzo, Nicole , Devuyst, Olivier , Raitakari, Olli , Fuchsberger, Christian , Gottesman, Omri , Franco, Oscar H. , Polasek, Ozren , Gasparini, Paolo , Munroe, Patricia B. , Ridker, Paul M. , Mitchell, Paul , Muntner, Paul , Meisinger, Christa , Smit, Johannes H. , Tayo, Bamidele , Kovacs, Peter , Wild, Philipp S. , Froguel, Philippe , Rettig, Rainer , Mäegi, Reedik , Biffar, Reiner , Schmidt, Reinhold , Middelberg, Rita P. S. , Carroll, Robert J. , Penninx, Brenda W. , Gorski, Mathias , Nalls, Michael , Scott, Rodney J. , Katz, Ronit , Sedaghat, Sanaz , Wild, Sarah H. , Kardia, Sharon L. R. , Ulivi, Sheila , Hwang, Shih-Jen , Enroth, Stefan , Kloiber, Stefan , Trompet, Stella , Feitosa, Mary F. , Stengel, Benedicte , Hancock, Stephen J. , Turner, Stephen T. , Rosas, Sylvia E. , Stracke, Sylvia , Harris, Tamara B. , Zeller, Tanja , Zemunik, Tatijana , Lehtimäki, Terho , Illig, Thomas , Isaacs, Aaron , Aspelund, Thor , Nikopensius, Tiit , Esko, Tonu , Tanaka, Toshiko , Gyllensten, Ulf , Völker, Uwe , Emilsson, Valur , Vitart, Veronique , Aalto, Ville , Gudnason, Vilmundur , Dehghan, Abbas , Chouraki, Vincent , Chen, Wei-Min , Igl, Wilmar , März, Winfried , Koenig, Wolfgang , Lieb, Wolfgang , Loos, Ruth J. F. , Liu, Yongmei , Snieder, Harold , Pramstaller, Peter P. , d'Adamo, Pio , Parsa, Afshin , O'Connell, Jeffrey R. , Susztak, Katalin , Hamet, Pavel , Tremblay, Johanne , de Boer, Ian H. , Böger, Carsten A. , Goessling, Wolfram , Chasman, Daniel I. , Köttgen, Anna , Adeyemo, Adebowale , Kao, W. H. Linda , Fox, Caroline S. , ICBP Consortium , AGEN Consortium , CARDIOGRAM , CHARGe-Heart Failure Group , ECHOGen Consortium , Dieffenbach, Aida Karina , Zonderman, Alan B. , Nolte, Ilja M. , van der Most, Peter J. , Chu, Audrey Y. , Wright, Alan F. , Shuldiner, Alan R. , Morrison, Alanna C. , Hofman, Albert , Smith, Albert V. , Dreisbach, Albert W. , Franke, Andre , Uitterlinden, Andre G. , Metspalu, Andres , Tonjes, Anke , Li, Man , Lupo, Antonio , Robino, Antonietta , Johansson, Åsa , Demirkan, Ayse , Kollerits, Barbara , Freedman, Barry I. , Ponte, Belen , Oostra, Ben A. , Paulweber, Bernhard , Kräemer, Bernhard K. , Mijatovic, Vladan , Mitchell, Braxton D. , Buckley, Brendan M. , Peralta, Carmen A. , Hayward, Caroline , Helmer, Catherine , Rotimi, Charles N. , Shaffer, Christian M. , Müeller, Christian , Sala, Cinzia , van Duijn, Cornelia M. , Garnaas, Maija , Saint-Pierre, Aude , Ackermann, Daniel , Shriner, Daniel , Ruggiero, Daniela , Toniolo, Daniela , Lu, Yingchang , Cusi, Daniele , Czamara, Darina , Ellinghaus, David , Siscovick, David S. , Tin, Adrienne , Ruderfer, Douglas , Gieger, Christian , Grallert, Harald , Rochtchina, Elena , Atkinson, Elizabeth J. , Holliday, Elizabeth G. , Boerwinkle, Eric , Salvi, Erika , Bottinger, Erwin P. , Murgia, Federico , Sorice, Rossella , Rivadeneira, Fernando , Ernst, Florian , Kronenberg, Florian , Hu, Frank B. , Navis, Gerjan J. , Curhan, Gary C. , Ehret, George B. , Homuth, Georg , Coassin, Stefan , Thun, Gian-Andri , Li, Yong , Pistis, Giorgio , Gambaro, Giovanni , Malerba, Giovanni , Montgomery, Grant W. , Eiriksdottir, Gudny , Jacobs, Gunnar , Li, Guo , Wichmann, H-Erich , Campbell, Harry , Schmidt, Helena
- Resource Type: journal article
- Date: 2016
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer
- Creator: Couch, Fergus J. , Kuchenbaecker, Karoline B. , Aittomäki, Kristiina , Ambrosone, Christine , Andrulis, Irene L. , Anton-Culver, Hoda , Arndt, Volker , Arun, Banu K. , Arver, Brita , Barile, Monica , Barkardottir, Rosa B. , Barrowdale, Daniel , Michailidou, Kyriaki , Scott, Rodney , Mendoza-Fandino, Gustavo A. , Nord, Siljie , Lilyquist, Janna , Olswold, Curtis , Hallberg, Emily , Agata, Simona , Ahsan, Habibul
- Resource Type: journal article
- Date: 2016
Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns
- Creator: Joubert, Bonnie R. , den Dekker, Herman T. , Håberg, Siri E. , Reese, Sarah E. , Peters, Marjolein J. , Kulle Andreassen, Bettina , Steegers, Eric A. P. , Nilsen, Roy M. , Vollset, Stein E. , Midttun, Øivind , Ueland, Per M. , Franco, Oscar H. , Felix, Janine F. , Dehghan, Abbas , de Jongste, Johan C. , Wu, Michael C. , Wang, Tianyuan , Peddada, Shyamal D. , Jaddoe, Vincent W. V. , Nystad, Wenche , Duijts, Liesbeth , London, Stephanie J. , Bohlin, Jon , Ligthart, Symen , Beckett, Emma , Tiemeier, Henning , van Meurs, Joyce B. , Uitterlinden, Andre G. , Hofman, Albert
- Resource Type: journal article
- Date: 2016
Unlocking new contrast in a scanning helium microscope
- Creator: Barr, M. , Fahy, A. , Martens, J. , Jardine, A. P. , Ward, D. J. , Ellis, J. , Allison, W. , Dastoor, P. C.
- Resource Type: journal article
- Date: 2016
Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy
- Creator: To, Eunice E. , Vlahos, Ross , Starkey, Malcolm R. , van der Sluis, Renee , Lewin, Sharon R. , Bozinovski, Steven , O'Neill, Luke A. J. , Quach, Tim , Porter, Christopher J. H. , Brooks, Doug A. , O'Leary, John J. , Selemidis, Stavros , Luong, Raymond , Halls, Michelle L. , Reading, Patrick C. , King, Paul T. , Chan, Christopher , Drummond, Grant R. , Sobey, Christopher G. , Broughton, Brad R. S.
- Resource Type: journal article
- Date: 2017
Genetic correlation between amyotrophic lateral sclerosis and schizophrenia
- Creator: McLaughlin, Russell L. , Schijven, Dick , Schall, Ulrich , Scott, Rodney J. , van Rheenen, Wouter , van Eijk, Kristel R. , O'Brien, Margaret , Project MinE GWAS Consortium, , Schizophrenia Working Group of the Psychiatric Genomics Consortium, , Henskens, Frans A. , Loughland, Carmel M. , Michie, Patricia T. , Khan, René S. , Ophoff, Roel A. , Goris, An , Bradley, Daniel G. , Al-Chalabi, Ammar , van den Berg, Leonard H. , Luykx, Jurjen J.
- Resource Type: journal article
- Date: 2017
Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness
- Creator: Willems, Sara M. , Wright, Daniel J. , Thalamuthu, Anbupalam , Mangino, Massimo , Liu, Jun , Demirkan, Ayse , Lek, Monkol , Xu, Liwen , Wang, Guan , Oldmeadow, Christopher , Gaulton, Kyle J. , Lotta, Luca A. , Day, Felix R. , Attia, John R. , Trajanoska, Katerina , Joshi, Peter K. , Morris, John A. , Matteini, Amy M. , Garton, Fleur C. , Grarup, Niels , Oskolkov, Nikolay
- Resource Type: journal article
- Date: 2017
Mismatch between marine plankton range movements and the velocity of climate change
- Creator: Chivers, William J. , Walne, Anthony W. , Hays, Graeme C.
- Resource Type: journal article
- Date: 2017
Organic coating on biochar explains its nutrient retention and stimulation of soil fertility
- Creator: Hagemann, Nikolas , Joseph, Stephen , McKenna, Amy , Albu, Mihaela , Mayrhofer, Claudia , Obst, Martin , Conte, Pellegrino , Dieguez-Alonso, Alba , Orsetti, Silvia , Subdiaga, Edisson , Behrens, Sebastian , Kappler, Andreas , Schmidt, Hans-Peter , Kammann, Claudia I. , Harter, Johannes , Borch, Thomas , Young, Robert B. , Varga, Krisztina , Taherymoosavi, Sarasadat , Elliott, K. Wade
- Resource Type: journal article
- Date: 2017
Potential increase in coastal wetland vulnerability to sea-level rise suggested by considering hydrodynamic attenuation effects
- Creator: Rodriguez, José F. , Saco, Patricia M. , Sandi, Steven , Saintilan, Neil , Riccardi, Gerardo
- Resource Type: journal article
- Date: 2017