A novel compound which sensitizes BRAF wild-type melanoma cells to vemurafenib in a TRIM16-dependent manner
- Creator: Sutton, Selina K. , Carter, Daniel R. , McArthur, Grant A. , Cheung, Belamy B. , Marshall, Glenn M. , Kim, Patrick , Tan, Owen , Arndt, Greg M. , Zhang, Xu Dong , Baell, Jonathan , Noll, Benjamin D. , Wang, Shudong , Kumar, Naresh
- Resource Type: journal article
- Date: 2016
Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors
- Creator: Smith, Amanda M. , Dun, Matthew D. , Toop, Hamish , Lock, Richard B. , Powell, Jason A. , Thomas, Daniel , Guthridge, Mark A. , Moore, Andrew , Ashman, Leonie K. , Skelding, Kathryn A. , Enjeti, Anoop , Verrills, Nicole M. , Lee, Erwin M. , Harrison, Celeste , Kahl, Richard , Flanagan, Hayley , Panicker, Nikita , Mashkani, Baratali , Don, Anthony S. , Morris, Jonathan
- Resource Type: journal article
- Date: 2016
Age related increase in mTOR activity contributes to the pathological changes in ovarian surface epithelium
- Creator: Bajwa, Preety , Nagendra, Prathima B. , Nielsen, Sarah , Sahoo, Subhransu S. , Bielanowicz, Amanda , Lombard, Janine M. , Wilkinson, J. Erby , Miller, Richard A. , Tanwar, Pradeep S.
- Resource Type: journal article
- Date: 2016
ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines.
- Creator: Lozinski, Mathew , Bowden, Nikola A. , Graves, Moira C. , Fay, Michael , Day, Bryan W. , Stringer, Brett W. , Tooney, Paul A.
- Resource Type: journal article
- Date: 2024
Bladder cancer survival in patients with NOD2 or CDKN2A variants
- Creator: Złowocka-Perłowska, Elżbieta , van de Wetering, Thierry , Tołoczko-Grabarek, Aleksandra , Scott, Rodney J. , Lubiński, Jan
- Resource Type: journal article
- Date: 2022
BRAF/MEK inhibitors promote CD47 expression that is reversible by ERK inhibition in melanoma
- Creator: Liu, Fen , Jiang, Chen Chen , Thorne, Rick F. , Jin, Lei , Wang, Qi , Zhang, Xu Dong , Yan, Xu Guang , Tseng, Hsin-Yi , Wang, Chun Yan , Zhang, Yuan Yuan , Yari, Hamed , La, Ting , Farrelly, Margaret , Guo, Su Tang
- Resource Type: journal article
- Date: 2017
BRAF/MEK inhibitors promote CD47 expression that is reversible by ERK inhibition in melanoma
- Creator: Liu, Fen , Jiang, Chen Chen , Thorne, Rick F. , Jin, Lei , Wang, Qi , Zhang, Xu Dong , Yan, Xu Guang , Tseng, Hsin-Yi , Wang, Chun Yan , Zhang, Yuan Yuan , Yari, Hamed , La, Ting , Farrelly, Margaret , Guo, Su Tang
- Resource Type: journal article
- Date: 2017
C3 deficiency ameliorates the negative effects of irradiation of the young brain on hippocampal development and learning
- Creator: Kalm, Marie , Andreasson, Ulf , Björk-Eriksson, Thomas , Zetterberg, Henrik , Pekny, Milos , Blennow, Kaj , Pekna, Marcela , Blomgren, Klas
- Resource Type: journal article
- Date: 2016
Chemosensitization of solid tumors by inhibition of Bcl-xL expression using DNAzyme
- Creator: Yu, Xiaohui , Yang, Lifang , Cairns, Murray J. , Dass, Crispin , Saravolac, Edward , Li, Xiong , Sun, Lun-Quan
- Resource Type: journal article
- Date: 2014
Connective tissue growth factor as a novel therapeutic target in high grade serous ovarian cancer
- Creator: Moran-Jones, Kim , Gloss, Brian S. , Spong, Suzanne M. , Scarlett, Christopher J. , Hacker, Neville F. , Ghosh, Sue , Mok, Samuel C. , Birrer, Michael J. , Samimi, Goli , Murali, Rajmohan , Chang, David K. , Colvin, Emily K. , Jones, Marc D. , Yuen, Samuel , Howell, Viive M. , Brown, Laura M. , Wong, Carol W.
- Resource Type: journal article
- Date: 2015
Germ cell-specific sustained activation of Wnt signalling perturbs spermatogenesis in aged mice, possibly through non-coding RNAs
- Creator: Kumar, Manish , Atkins, Joshua , Cairns, Murray , Ali, Ayesha , Tanwar, Pradeep S.
- Resource Type: journal article
- Date: 2016
Histone deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1
- Creator: Shahbazi, Jeyran , Scarlett, Christopher J. , Lock, Richard B. , Liu, Tao , Norris, Murray D. , Liu, Bing , Haber, Michelle , Tee, Andrew E. , Carrier, Alice , Biankin, Aandrew V. , London, Wendy B. , Marshall, Glenn M.
- Resource Type: journal article
- Date: 2014
Identification of the microRNA networks contributing to macrophage differentiation and function
- Creator: Zhou, Hong , Zhang, Jie , Eyers, Fiona , Xiang, Yang , Herbert, Cristan , Tay, Hock L. , Foster, Paul S. , Yang, Ming
- Resource Type: journal article
- Date: 2016
Inhibition of extracellular matrix mediated TGF-β signalling suppresses endometrial cancer metastasis
- Creator: Sahoo, Subhransu S. , Quah, Min Yuan , Nielsen, Sarah , Atkins, Joshua , Au, Gough G. , Cairns, Murray J. , Nahar, Pravin , Lombard, Janine M. , Tanwar, Pradeep S.
- Resource Type: journal article
- Date: 2017
INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas
- Creator: Chi, Meng Na , Guo, Su Tang , Croft, Amanda , Hondermarck, Hubert , Scolyer, Richard A. , Jiang, Chen Chen , Zhang, Xu Dong , Wilmott, James S. , Guo, Xiang Yun , Yan, Xu Guang , Wang, Chun Yan , Liu, Xiao Ying , Jin, Lei , Tseng, Hsin-Yi , Liu, Tao
- Resource Type: journal article
- Date: 2015
Low tumour-infiltrating lymphocyte density in primary and recurrent glioblastoma
- Creator: Maddison, Kelsey , Graves, Moira C. , Bowden, Nikola A. , Fay, Michael , Vilain, Ricardo E. , Faulkner, Sam , Tooney, Paul A.
- Resource Type: journal article
- Date: 2021
miR-518f-5p decreases tetraspanin CD9 protein levels and differentially affects non-tumourigenic prostate and prostate cancer cell migration and adhesion
- Creator: Bond, Danielle R. , Naudin, Crystal , Carroll, Adam P. , Goldie, Belinda J. , Brzozowski, Joshua S. , Jankowski, Helen M. , Cairns, Murray J. , Ashman, Leonie K. , Scarlett, Christopher J. , Weidenhofer, Judith
- Resource Type: journal article
- Date: 2018
Noxa upregulation by oncogenic activation of MEK/ERK through CREB promotes autophagy in human melanoma cells
- Creator: Liu, Yi Lun , Lai, Fritz , Jin, Lei , Zhang, Xu Dong , Wilmott, James S. , Yan, Xu Guang , Liu, Xiao Ying , Luan, Qi , Guo, Su Tang , Jiang, Chen Chen , Tseng, Hsin-Yi , Scolyer, Richard A.
- Resource Type: journal article
- Date: 2014
Ovarian hormones through Wnt signalling regulate the growth of human and mouse ovarian cancer initiating lesions
- Creator: Nagendra, Prathima B. , Goad, Jyoti , Nielsen, Sarah , Rassam, Loui , Lombard, Janine M. , Nahar, Pravin , Tanwar, Pradeep S.
- Resource Type: journal article
- Date: 2016
Overactive mTOR signaling leads to endometrial hyperplasia in aged women and mice
- Creator: Bajwa, Preety , Nielsen, Sarah , Lombard, Janine M. , Rassam, Loui , Nahar, Pravin , Rueda, Bo R. , Wilkinson, J. Erby , Miller, Richard A. , Tanwar, Pradeep S.
- Resource Type: journal article
- Date: 2017