Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors
- Creator: Smith, Amanda M. , Dun, Matthew D. , Toop, Hamish , Lock, Richard B. , Powell, Jason A. , Thomas, Daniel , Guthridge, Mark A. , Moore, Andrew , Ashman, Leonie K. , Skelding, Kathryn A. , Enjeti, Anoop , Verrills, Nicole M. , Lee, Erwin M. , Harrison, Celeste , Kahl, Richard , Flanagan, Hayley , Panicker, Nikita , Mashkani, Baratali , Don, Anthony S. , Morris, Jonathan
- Resource Type: journal article
- Date: 2016
Peripheral lipopolysaccharide challenge induces long-term changes in tyrosine hydroxylase regulation in the adrenal medulla
- Creator: Ong, Lin Kooi , Page, Scott , Briggs, Gabrielle D. , Guan, Liying , Dun, Matthew D. , Verrills, Nicole M. , Dunkley, Peter R. , Dickson, Phillip W.
- Resource Type: journal article
- Date: 2017
Controlling the cell cycle: the role of calcium/calmodulin-stimulated protein kinases I and II
- Creator: Skelding, Kathryn A. , Rostas, John A. P. , Verrills, Nicole M.
- Resource Type: journal article
- Date: 2011
Basal protein phosphatase 2A activity restrains cytokine expression: role for MAPKs and tristetraprolin
- Creator: Rahman, Md. Mostafizur , Rumzhum, Nowshin N. , Morris, Jonathan C. , Clark, Andrew R. , Verrills, Nicole M. , Ammit, Alaina J.
- Resource Type: journal article
- Date: 2015
Involvement of vacuolar H⁺₋ATPase in killing of human melanoma cells by the sphingosine kinase analogue FTY720
- Creator: Tay, Kwang Hong , Liu, Xiaoying , Chi, Mengna , Jin, Lei , Jiang, Chen Chen , Guo, Su Tang , Verrills, Nicole M. , Tseng, Hsin-Yi , Zhang, Xu Dong
- Resource Type: journal article
- Date: 2015
Identification of novel diagnostic biomarkers for asthma and chronic obstructive pulmonary disease
- Creator: Verrills, Nicole M. , Irwin, Jennifer A. , He, Xiao Yan , Wood, Lisa G. , Powell, Heather , Simpson, Jodie L. , McDonald, Vanessa M. , Sim, Alistair , Gibson, Peter G.
- Resource Type: journal article
- Date: 2011
Essential requirement for PP2A inhibition by the oncogenic receptor c-KIT suggests PP2A reactivation as a strategy to treat c-KIT⁺ cancers
- Creator: Roberts, Kathryn G. , Smith, Amanda M. , Sim, Alistair T. R. , Ashman, Leonie K. , Verrills, Nicole M. , McDougall, Fiona , Carpenter, Helen , Horan, Martin , Neviani, Paolo , Powell, Jason A. , Thomas, Daniel , Guthridge, Mark A. , Perrotti, Danilo
- Resource Type: journal article
- Date: 2010
Activating protein phosphatase 2A (PP2A) enhances tristetraprolin (TTP) anti-inflammatory function in A549 lung epithelial cells
- Creator: Rahman, Md. Mostafizur , Rumzhum, Nowshin N. , Hansbro, Philip M. , Morris, Jonathan C. , Clark, Andrew R. , Verrills, Nicole M. , Ammit, Alaina J.
- Resource Type: journal article
- Date: 2016
Expression of renin–angiotensin system (RAS) components in endometrial cancer
- Creator: Delforce, Sarah J. , Lumbers, Eugenie R. , Corbisier de Meaultsart, Celine , Wang, Yu , Proietto, Anthony , Otton, Geoffrey , Scurry, Jim , Verrills, Nicole M. , Scott, Rodney J. , Pringle, Kirsty G.
- Resource Type: journal article
- Date: 2017
Protein phosphatase 2A carboxymethylation and regulatory B subunits differentially regulate mast cell degranulation
- Creator: Kranias, Gregory , Watt, Lauren F. , Carpenter, Helen , Holst, Jeff , Ludowyke, Russell , Strack, Stefan , Sim, Alistair T. R. , Verrills, Nicole M.
- Resource Type: journal article
- Date: 2010
Development of novel PP2A activators for use in the treatment of acute myeloid leukaemia
- Creator: Toop, Hamish D. , Dun, Matthew D. , Ross, Bryony K. , Flanagan, Hayley M. , Verrills, Nicole M. , Morris, Jonathan C.
- Resource Type: journal article
- Date: 2016
Essential role of protein phosphatase 2A in metaphase II arrest and activation of mouse eggs shown by okadaic acid, dominant negative protein phosphatase 2A, and FTY720
- Creator: Chang, Heng-Yu , Jennings, Phoebe C. , Stewart, Jessica , Verrills, Nicole M. , Jones, Keith T.
- Resource Type: journal article
- Date: 2011
TLR2 ligation induces corticosteroid insensitivity in A549 lung epithelial cells: anti-inflammatory impact of PP2A activators
- Creator: Rahman, Md. Mostafizur , Prabhala, Pavan , Rumzhum, Nowshin N. , Patel, Brijeshkumar S. , Wickop, Thomas , Hansbro, Phillip M. , Verrills, Nicole M. , Ammit, Alaina J.
- Resource Type: journal article
- Date: 2016
A systematic evaluation of the safety and toxicity of fingolimod for its potential use in the treatment of acute myeloid leukaemia
- Creator: Enjeti, Anoop K. , D'Crus, Angel , Melville, Kathleen , Verrills, Nicole M. , Rowlings, Philip
- Resource Type: journal article
- Date: 2016
Mast cell function: regulation of degranulation by serine/threonine phosphatases
- Creator: Sim, Alistair T. R. , Ludowyke, Russell I. , Verrills, Nicole M.
- Resource Type: journal article
- Date: 2006
Regulation of CaMKII by phospho-Thr253 or phospho-Thr286 sensitive targeting alters cellular function
- Creator: Skelding, Kathryn A. , Suzuki, Tatsuo , Gordon, Sarah , Xue, Jing , Verrills, Nicole M. , Dickson, Phillip W. , Rostas, John A. P.
- Resource Type: journal article
- Date: 2010
Functional importance of PP2A regulatory subunit loss in breast cancer
- Creator: Watt, Lauren F. , Panicker, Nikita , Mannan, Abdul , Copeland, Ben , Kahl, Richard G. S. , Dun, Matthew D. , Young, Barbara , Roselli, Severine , Verrills, Nicole M.
- Resource Type: journal article
- Date: 2017
Proteomic analysis reveals a novel role for the actin cytoskeleton in vincristine resistant childhood leukemia: an in vivo study
- Creator: Verrills, Nicole M. , Liem, Natalia L. , Liaw, Tracey Y. E. , Hood, Brian D. , Lock, Richard B. , Kavallaris, Maria
- Resource Type: journal article
- Date: 2006
Ser/thr phosphatases: the new frontier for myeloid leukemia therapy?
- Creator: Smith, Amanda M. , Roberts, Kathryn G. , Verrills, Nicole M.
- Resource Type: book chapter
- Date: 2011
Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons
- Creator: Goldie, Belinda J. , Dun, Matthew D. , Lin, Minjie , Smith, Nathan D. , Verrills, Nicole M. , Dayas, Christopher V. , Cairns, Murray J.
- Resource Type: journal article
- Date: 2014