Cross-Cancer Genome-Wide Association Study of Endometrial Cancer and Epithelial Ovarian Cancer Identifies Genetic Risk Regions Associated with Risk of Both Cancers
- Creator: Glubb, Dylan M. , Thompson, Deborah J. , Bermisheva, Marina , McNeish, IA , Menon, U , Modugno, F , Moysich, KB , Nevanlinna, H , Odunsi, K , Olsson, H , Orsulic, S , Osorio, A , Palli, D , Bernardini, Marcus Q. , Park-Simon, T-W , Pearce, CL , Pejovic, T , Permuth, JB , Podgorska, A , Ramus, SJ , Rebbeck, TR , Riggan, MJ , Risch, HA , Rothstein, JH , Bischof, Katharina , Runnebaum, IB , Scott, RJ , Sellers, TA , Senz, J , Setiawan, VW , Siddiqui, N , Sieh, W , Spiewankiewicz, B , Sutphen, R , Swerdlow, AJ , Bjorge, Line , Szafron, LM , Teo, SH , Thompson, PJ , Thomsen, LCV , Titus, L , Tone, A , Tumino, R , Turman, C , Vanderstichele, A , Edwards, DV , Bodelon, Clara , Vergote, I , Vierkant, RA , Wang, Z , Wang-Gohrke, S , Webb, PM , White, E , Whittemore, AS , Winham, SJ , Wu, X , Wu, AH , Brand, Alison H. , Yannoukakos, D , Spurdle, AB , O'Mara, TA , Brenton, James D. , Brinton, Louise A. , Bruinsma, Fiona , Buchanan, Daniel D. , Aben, Katja K. H. , Burghaus, S , Butzow, R , Cai, H , Carney, ME , Chanock, SJ , Chen, C , Chen, XQ , Chen, Z , Cook, LS , Cunningham, JM , Alsulimani, Ahmad , De Vivo, I , DeFazio, A , Doherty, JA , Dork, T , du Bois, A , Dunning, AM , Durst, M , Edwards, T , Edwards, RP , Ekici, AB , Amant, Frederic , Ewing, A , Fasching, PA , Ferguson, S , Flanagan, JM , Fostira, F , Fountzilas, G , Friedenreich, CM , Gao, B , Gaudet, MM , Gawelko, J , Annibali, Daniela , Gentry-Maharaj, A , Giles, GG , Glasspool, R , Goodman, MT , Gronwald, J , Harris, HR , Harter, P , Hein, A , Heitz, F , Hildebrandt, MAT , Attia, John , Hillemanns, P , Hogdall, E , Hogdall, CK , Holliday, Elizabeth G. , Huntsman, DG , Huzarski, T , Jakubowska, A , Jensen, A , Jones, ME , Karlan, BY , Barricarte, Aurelio , Karnezis, A , Kelley, JL , Khusnutdinova, E , Killeen, JL , Kjaer, SK , Klapdor, R , Kobel, M , Konopka, B , Konstantopoulou, I , Kopperud, RK , Beckmann, Matthias W. , Koti, M , Kraft, P , Kupryjanczyk, J , Lambrechts, D , Larson, MC , Le Marchand, L , Lele, S , Lester, J , Li, AJ , Liang, D , Berchuck, Andrew , Liebrich, C , Lipworth, L , Lissowska, J , Lu, L , Lu, KH , Macciotta, A , Mattiello, A , May, T , McAlpine, JN , McGuire, V
- Resource Type: journal article
- Date: 2021
Rare germline copy number deletions of likely functional importance are implicated in endometrial cancer predisposition
- Creator: Moir-Meyer, Gemma L. , Pearson, John F. , Pharoah, Paul D. , Dunning, Alison M. , Thompson, Deborah J. , Easton, Douglas F. , Spurdle, Amanda B. , Walker, Logan C. , Lose, Felicity , The Australian National Endometrial Cancer Study Group, , Scott, Rodney J. , McEvoy, Mark , Attia, John , Holliday, Elizabeth G. , The Hunter Community Study, , Studies of Epidemiology and Risk Factors in Cancer Heredity,
- Resource Type: journal article
- Date: 2015
GWAS meta-analysis of 16 852 women identifies new susceptibility locus for endometrial cancer
- Creator: Chen, Maxine M. , O'Mara, Tracy A. , Cheng, Timothy H. T. , Cook, Linda S. , Crous-Bou, Marta , Doherty, Jennifer , Friedenreich, Christine M. , Garcia-Closas, Montserrat , Gaudet, Mia M. , Gorman, Maggie , Haiman, Christopher , Hankinson, Susan E. , Thompson, Deborah J. , Holliday, Elizabeth G. , Painter, Jodie N. , Australian National Endometrial Cancer Study Group (ANECS), , Attia, John , Black, Amanda , Brinton, Louise , Chanock, Stephen , Chen, Chu
- Resource Type: journal article
- Date: 2016
Genetic risk score mendelian randomization shows that obesity measured as body mass index, but not waist:hip ratio, is causal for endometrial cancer
- Creator: Painter, Jodie N. , O'Mara, Tracy A. , Scott, Rodney J. , Ahmed, Shahana , Healey, Catherine S. , Shah, Mitul , Gorman, Maggie , Martin, Lynn , Hodgson, Shirley V. , Beckmann, Matthias W. , Ekici, Arif B. , Fasching, Peter A. , Marquart, Louise , Hein, Alexander , Rübner, Matthias , Czene, Kamilla , Darabi, Hatef , Hall, Per , Li, Jingmei , Dörk, Thilo , Dürst, Matthias , Hillemanns, Peter , Runnebaum, Ingo B. , Webb, Penelope M. , Amant, Frederic , Annibali, Daniela , Depreeuw, Jeroen , Lambrechts, Diether , Neven, Patrick , Cunningham, Julie M. , Dowdy, Sean C. , Goode, Ellen L. , Fridley, Brooke L. , Winham, Stacey J. , Attia, John , Njølstad, Tormund S. , Salvesen, Helga B. , Trovik, Jone , Werner, Henrica M. J. , Ashton, Katie A. , Otton, Geoffrey , Proietto, Anthony , Mints, Miriam , Tham, Emma , Bolla, Manjeet K. , Medland, Sarah E. , Michailidou, Kyriaki , Wang, Qin , Tyrer, Jonathan P. , Hopper, John L. , Peto, Julian , Swerdlow, Anthony J. , Burwinkel, Barbara , Brenner, Hermann , Meindl, Alfons , Brauch, Hiltrud , Cheng, Timothy , Lindblom, Annika , Chang-Claude, Jenny , Couch, Fergus J. , Giles, Graham G. , Kristensen, Vessela N. , Cox, Angela , Pharoah, Paul D. P. , Tomlinson, Ian , Dunning, Alison M. , Easton, Douglas F. , Dennis, Joe , Thompson, Deborah J. , Spurdle, Amanda B. , Holliday, Elizabeth G. , McEvoy, Mark
- Resource Type: journal article
- Date: 2016
CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancer
- Creator: Thompson, Deborah J. , O'Mara, Tracy A. , Martin, Lynn , Hodgson, Shirley , Michailidou, Kyriaki , Tyrer, Jonathan P. , Maranian, Mel J. , Hall, Per , Czene, Kamila , Darabi, Hatef , Li, Jingmei , Fasching, Peter A. , Glubb, Dylan M. , Ashton, Katie , Proietto, Tony , Otton, Geoffrey , Scott, Rodney J , McEvoy, Mark , Attia, John , Holliday, Elizabeth G. , Painter, Jodie N. , Cheng, Timothy , Folkerd, Elizabeth , Doody, Deborah , Dennis, Joe , Webb, Penelope M. , Gorman, Maggie
- Resource Type: journal article
- Date: 2016
Five endometrial cancer risk loci identified through genome-wide association analysis
- Creator: Cheng, Timothy H. T. , Thompson, Deborah J. , Gorman, Maggie , Martin, Lynn , National Study of Endometrial Cancer Genetics Group (NSECG), , Hodgson, Shirley , Webb, Penelope M. , Australian National Endometrial Cancer Study Group (ANECS), , Attia, John , Holliday, Elizabeth G. , McEvoy, Mark , Scott, Rodney J. , O'Mara, Tracy A. , Dowdy, Sean C. , Ashton, Katie , Otton, Geoffrey , Proietto, Tony , Painter, Jodie N. , Glubb, Dylan M. , Flach, Susanne , Lewis, Annabelle , French, Juliet D. , Freeman-Mills, Luke , Church, David
- Resource Type: journal article
- Date: 2016
Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer
- Creator: O'Mara, Tracy A. , Glubb, Dylan M. , Ashton, Katie , Proietto, Tony , Otton, Geoffrey , Shah, Mitul , Ahmed, Shahana , Healey, Catherine S. , Gorman, Maggie , Martin, Lynn , National Study of Endometrial Cancer Genetics Group (NSECG), , Hodgson, Shirley , Painter, Jodie N. , Fasching, Peter A. , Hein, Alexander , Beckmann, Matthias W. , Ekici, Arif B. , Hall, Per , Czene, Kamila , Darabi, Hatef , Li, Jingmei , Dürst, Matthias , Runnebaum, Ingo , Cheng, Timothy , Hillemanns, Peter , Dörk, Thilo , Lambrechts, Diether , Depreeuw, Jeroen , Annibali, Daniela , Amant, Frederic , Zhao, Hui , Goode, Ellen L. , Dowdy, Sean C. , Fridley, Brooke L. , Dennis, Joe , Winham, Stacey J. , Salvesen, Helga B. , Njølstad, Tormund S. , Trovik, Jone , Werner, Henrica M. J. , Tham, Emma , Liu, Tao , Mints, Miriam , RENDOCAS, , Bolla, Manjeet K. , Australian National Endometrial Cancer Study Group (ANECS), , Michailidou, Kyriaki , Tyrer, Jonathan P. , Wang, Qin , Hopper, John L. , AOCS Group, , Peto, Julian , Swerdlow, Anthony J. , Burwinkel, Barbara , Brenner, Hermann , Meindl, Alfons , Attia, John , Brauch, Hiltrud , Lindblom, Annika , Chang-Claude, Jenny , Couch, Fergus J. , Giles, Graham G. , Kristensen, Vessela N. , Cox, Angela , Pharoah, Paul D. P. , Dunning, Alison M. , Tomlinson, Ian , Holliday, Elizabeth G. , Easton, Douglas F. , Thompson, Deborah J. , Spurdle, Amanda B. , McEvoy, Mark , Scott, Rodney J.
- Resource Type: journal article
- Date: 2015
Evidence of a causal association between insulinemia and endometrial cancer: a Mendelian randomization analysis
- Creator: Nead, Kevin T. , Sharp, Stephen J. , Easton, Douglas F. , Holliday, Elizabeth , Lotta, Luca A. , O'Mara, Tracy , McEvoy, Mark , Pharoah, Paul D. P. , Scott, Rodney J. , Spurdle, Amanda B. , Langenberg, Claudia , Wareham, Nicholas J. , Thompson, Deborah J. , Scott, Robert A. , Painter, Jodie N. , Savage, David B. , Semple, Robert K. , Barker, Adam , Perry, John R. B. , Attia, John , Dunning, Alison M.
- Resource Type: journal article
- Date: 2015
Genome-wide association study identifies a common variant associated with risk of endometrial cancer
- Creator: Spurdle, Amanda B. , Thompson, Deborah J. , Fahey, Paul , Montgomery, Grant W. , Webb, Penelope M. , Fasching, Peter A. , Beckmann, Matthias W. , Ekici, Arif B. , Hein, Alexander , Lambrechts, Diether , Coenegrachts, Lieve , Vergote, Ignace , Ahmed, Shahana , Amant, Frederic , Salvesen, Helga B. , Trovik, Jone , Njolstad, Tormund S. , Helland, Harald , Scott, Rodney J. , Ashton, Katie , Proietto, Tony , Otton, Geoffrey , National Study of Endometrial Cancer Genetics Group, , Ferguson, Kaltin , Tomlinson, Ian , Gorman, Maggie , Howarth, Kimberley , Hodgson, Shirley , Garcia-Closas, Montserrat , Wentzensen, Nicolas , Yang, Hannah , Chanock, Stephen , Hall, Per , Czene, Kamila , Healey, Catherine S. , Liu, Jianjun , Li, Jingmei , Shu, Xiao-Ou , Zheng, Wei , Long, Jirong , Xiang, Yong-Bing , Shah, Mitul , Morrison, Jonathan , Michailidou, Kyriaki , Pharoah, Paul D. , O'Mara, Tracy , Dunning, Alison M. , Easton, Douglas F. , Walker, Logan C, , Montgomery, Stephen B. , Dermitzakis, Emmanouil T. , Australian National Endometrial Cancer Study Group,
- Resource Type: journal article
- Date: 2011
Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk.
- Creator: Painter, Jodie N. , O'Mara, Tracy A. , Healey, Catherine S. , Fridley, Brooke L. , Børresen-Dale, Anne-Lise , Kristensen, Vessela N. , Cox, Angela , Swerdlow, Anthony J. , Orr, Nicholas , Bolla, Manjeet K. , Wang, Qin , Palmieri Weber, Rachel , Chen, Zhihua , Kaufmann, Susanne , Shah, Mitul , French, Juliet D. , Pharoah, Paul D. P. , Dunning, Alison M. , Tomlinson, Ian , Easton, Douglas F. , Edwards, Stacey L. , Thompson, Deborah J. , Spurdle, Amanda B. , Hillman, Kristine M. , Walpole, Carina , Moya, Leire , Pollock, Pamela , Jones, Angela , Howarth, Kimberley , Martin, Lynn , Gorman, Maggie , Batra, Jyotsna , Hodgson, Shirley , National Study of Endometrial Cancer Genetics Group (NSECG) , CHIBCHA Consortium , De Polanco, Ma. Magdalena Echeverry , Sans, Monica , Carracedo, Angel , Castellvi-Bel, Sergi , Rojas-Martinez, Augusto , Santos, Erika , Teixeira, Manuel R. , Cheng, Timothy , Carvajal-Carmona, Luis , Shu, Xiao-Ou , Long, Jirong , Zheng, Wei , Xiang, Yong-Bing , The Australian National Endometrial Cancer Study Group (ANECS) , Montgomery, Grant W. , Webb, Penelope M. , Scott, Rodney J. , McEvoy, Mark , Lose, Felicity A. , Attia, John , Holliday, Elizabeth , Martin, Nicholas G. , Nyholt, Dale R. , Henders, Anjali K. , Fasching, Peter A. , Hein, Alexander , Beckmann, Matthias W. , Renner, Stefan P. , Dörk, Thilo , Dennis, Joe , Hillemanns, Peter , Dürst, Matthias , Runnebaum, Ingo , Lambrechts, Diether , Coenegrachts, Lieve , Schrauwen, Stefanie , Amant, Frederic , Winterhoff, Boris , Dowdy, Sean C. , Goode, Ellen L. , Michailidou, Kyriaki , Teoman, Attila , Salvesen, Helga B. , Trovik, Jone , Njolstad, Tormund S. , Werner, Henrica M. J. , Ashton, Katie , Proietto, Tony , Otton, Geoffrey , Tzortzatos, Gerasimos , Mints, Miriam , Tyrer, Jonathan P. , Tham, Emma , RENDOCAS , Hall, Per , Czene, Kamila , Liu, Jianjun , Li, Jingmei , Hopper, John L. , Southey, Melissa C. , Australian Ovarian Cancer Study (AOCS) , Ekici, Arif B. , Ahmed, Shahana , Ruebner, Matthias , Johnson, Nicola , Peto, Julian , Burwinkel, Barbara , Marme, Frederik , Brenner, Hermann , Dieffenbach, Aida K. , Miendl, Alfons , Brauch, Hiltrud , The GENICA Network, , Ferguson, Kaltin , Lindblom, Annika , Depreeuw, Jeroen , Moisse, Matthieu , Chang-Claude, Jenny , Rudolph, Anja , Couch, Fergus J. , Olsen, Janet E. , Giles, Graham G. , Bruinsma, Fiona , Cunnigham, Julie M.
- Resource Type: journal article
- Date: 2015
Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk
- Creator: Carvajal-Carmona, Luis G. , O Mara, Tracy A. , Pooley, Karen , Beesley, Jonathan , Cheng, Timothy , Jones, Angela , Howarth, Kimberley , Martin, Lynn , Gorman, Maggie , Hodgson, Shirley , National Study of Endometrial Cancer Genetics Group (NSECG) , . , The Australian National Endometrial Cancer Study Group (ANECS), . , Painter, Jodie N. , Wentzensen, Nicholas , Fasching, Peter A. , Hein, Alexander , Beckmann, Matthias W. , Renner, Stefan P. , Dörk, Thilo , Hillemanns, Peter , Dürst, Matthias , Runnebaum, Ingo , Lambrechts, Diether , Lose, Felicity A. , Coenegrachts, Lieve , Schrauwen, Stefanie , Amant, Frederic , Winterhoff, Boris , Dowdy, Sean C. , Goode, Ellen L. , Teoman, Attila , Salvesen, Helga B. , Trovik, Jone , Njolstad, Tormund S. , Dennis, Joe , Werner, Henrica M. J. , Scott, Rodney J. , Ashton, Katie , Proietto, Tony , Otton, Geoffrey , Wersäll, Ofra , Mints, Miriam , Tham, Emma , RENDOCAS, , Hall, Per , Michailidou, Kyriaki , Czene, Kamila , Liu, Jianjun , Li, Jingmei , Hopper, John L. , Southey, Melissa C. , Australian Ovarian Cancer Study (AOCS), . , Ekici, Arif B. , Ruebner, Matthias , Johnson, Nichola , Peto, Julian , Tyrer, Jonathan P. , Burwinkel, Barbara , Marme, Frederik , Brenner, Hermann , Dieffenbach, Aida K. , Meindl, Alfons , Brauch, Hiltrud , The GENICA Network, . , Lindblom, Annika , Depreeuw, Jeroen , Moisse, Matthieu , Ahmed, Shahana , Chang-Claude, Jenny , Rudolph, Anja , Couch, Fergus J. , Olson, Janet E. , Giles, Graham G. , Bruinsma, Fiona , Cunningham, Julie M. , Fridley, Brooke L. , Børresen-Dale, Anne-Lise , Kristensen, Vessela N. , Ferguson, Kaltin , Cox, Angela , Swerdlow, Anthony J. , Orr, Nicholas , Bolla, Manjeet K. , Wang, Qin , Palmieri Weber, Rachel , Chen, Zhihua , Shah, Mitul , Pharoah, Paul D. P. , Dunning, Alison M. , Healey, Catherine S. , Tomlinson, Ian , Easton, Douglas F. , Spurdle, Amanda B. , Thompson, Deborah J.
- Resource Type: journal article
- Date: 2015
A common variant at the 14q32 endometrial cancer risk locus activates AKT1 through YY1 binding
- Creator: Painter, Jodie N. , Kaufmann, Susanne , Hoivik, Erling A. , Goode, Ellen L. , Scott, Rodney J. , Tomlinson, Ian , Dunning, Alison M. , Easton, Douglas F. , French, Juliet D. , Salvesen, Helga B. , Pollock, Pamela M. , Thompson, Deborah J. , O'Mara, Tracy A. , Spurdle, Amanda B. , Edwards, Stacey L. , Hillman, Kristine M. , Sivakumaran, Haran , Darabi, Hatef , Cheng, Timothy H.T. , Pearson, John , Kazakoff, Stephen , Waddell, Nicola
- Resource Type: journal article
- Date: 2016