Altered LKB1/AMPK/TSC1/TSC2/mTOR signaling causes disruption of sertoli cell polarity and spermatogenesis
- Creator: Tanwar, Pradeep S. , Kaneko-Tarui, Tomoko , Zhang, LiHua , Teixeira, Jose M.
- Resource Type: journal article
- Date: 2012
Stromal liver kinase B1 STK11 signaling loss induces oviductal adenomas and endometrial cancer by activating mammalian target of Rapamycin Complex 1
- Creator: Tanwar, Pradeep S. , Kaneko-Tarui, Tomoko , Zhang, LiHua , Tanaka, Yoshihiro , Crum, Christopher P. , Teixeira, Jose M.
- Resource Type: journal article
- Date: 2012
PTEN loss and HOXA10 expression are associated with ovarian endometrioid adenocarcinoma differentiation and progression
- Creator: Tanwar, Pradeep S. , Kaneko-Tarui, Tomoko , Lee, Ho-Joon , Zhang, LiHua , Teixeira, Jose M.
- Resource Type: journal article
- Date: 2013
Loss of LKB1 and PTEN tumor suppressor genes in the ovarian surface epithelium induces papillary serous ovarian cancer
- Creator: Tanwar, Pradeep S. , Mohapatra, Gayatry , Chiang, Sarah , Engler, David A. , Zhang, LiHua , Kaneko-Tarui, Tomoko , Ohguchi, Yasuyo , Birrer, Michael J. , Teixeira, Jose M.
- Resource Type: journal article
- Date: 2014
Age related increase in mTOR activity contributes to the pathological changes in ovarian surface epithelium
- Creator: Bajwa, Preety , Nagendra, Prathima B. , Nielsen, Sarah , Sahoo, Subhransu S. , Bielanowicz, Amanda , Lombard, Janine M. , Wilkinson, J. Erby , Miller, Richard A. , Tanwar, Pradeep S.
- Resource Type: journal article
- Date: 2016
Epithelial Wnt/βcatenin signalling is essential for epididymal coiling
- Creator: Kumar, Manish , Syed, Shafiq M. , Taketo, Makoto M. , Tanwar, Pradeep S.
- Resource Type: journal article
- Date: 2016
Germ cell specific overactivation of WNT/βcatenin signalling has no effect on folliculogenesis but causes fertility defects due to abnormal foetal development
- Creator: Kumar, Manish , Camlin, Nicole J. , Holt, Janet E. , Teixeira, Jose M. , McLaughlin, Elieen A. , Tanwar, Pradeep S.
- Resource Type: journal article
- Date: 2016
Germ cell-specific sustained activation of Wnt signalling perturbs spermatogenesis in aged mice, possibly through non-coding RNAs
- Creator: Kumar, Manish , Atkins, Joshua , Cairns, Murray , Ali, Ayesha , Tanwar, Pradeep S.
- Resource Type: journal article
- Date: 2016
Ovarian hormones through Wnt signalling regulate the growth of human and mouse ovarian cancer initiating lesions
- Creator: Nagendra, Prathima B. , Goad, Jyoti , Nielsen, Sarah , Rassam, Loui , Lombard, Janine M. , Nahar, Pravin , Tanwar, Pradeep S.
- Resource Type: journal article
- Date: 2016
Canonical Wnt/β-catenin signaling regulates postnatal mouse epididymal development but does not affect epithelial cell differentiation
- Creator: Kumar, Manish , Tanwar, Pradeep S.
- Resource Type: journal article
- Date: 2017
Differential Wnt signaling activity limits epithelial gland development to the anti-mesometrial side of the mouse uterus
- Creator: Goad, Jyoti , Ko, Yi-An , Kumar, Manish , Syed, Shafiq M. , Tanwar, Pradeep S.
- Resource Type: journal article
- Date: 2017
In vivo genetic cell lineage tracing reveals that oviductal secretory cells self-renew and give rise to ciliated cells
- Creator: Ghosh, Arnab , Syed, Shafiq M. , Tanwar, Pradeep S.
- Resource Type: journal article
- Date: 2017
Inhibition of extracellular matrix mediated TGF-β signalling suppresses endometrial cancer metastasis
- Creator: Sahoo, Subhransu S. , Quah, Min Yuan , Nielsen, Sarah , Atkins, Joshua , Au, Gough G. , Cairns, Murray J. , Nahar, Pravin , Lombard, Janine M. , Tanwar, Pradeep S.
- Resource Type: journal article
- Date: 2017
Overactive mTOR signaling leads to endometrial hyperplasia in aged women and mice
- Creator: Bajwa, Preety , Nielsen, Sarah , Lombard, Janine M. , Rassam, Loui , Nahar, Pravin , Rueda, Bo R. , Wilkinson, J. Erby , Miller, Richard A. , Tanwar, Pradeep S.
- Resource Type: journal article
- Date: 2017
Specific deletion of LKB1/Stk11 in the Müllerian duct mesenchyme drives hyperplasia of the periurethral stroma and tumorigenesis in male mice
- Creator: George, Jitu W. , Patterson, Amanda L. , Tanwar, Pradeep S. , Kajdacsy-Balla, André , Prins, Gail S. , Teixeira, Jose M.
- Resource Type: journal article
- Date: 2017
Adipose-Derived VEGF–mTOR Signaling Promotes Endometrial Hyperplasia and Cancer: Implications for Obese Women
- Creator: Sahoo, Subhransu S. , Lombard, Janine M. , Ius, Yvette , O'Sullivan, Rachel , Wood, Lisa G. , Nahar, Pravin , Jaaback, Kenneth , Tanwar, Pradeep S.
- Resource Type: journal article
- Date: 2018
Extracellular matrix (ECM) activates β-catenin signaling in uterine fibroids
- Creator: Ko, Yi-An , Jamaluddin, M. Fairuz B. , Adebayo, Mariam , Bajwa, Preety , Scott, Rodney J. , Dharmarajan, Arunasalam M. , Nahar, Pravin , Tanwar, Pradeep S.
- Resource Type: journal article
- Date: 2018
Oestrogen fuels the growth of endometrial hyperplastic lesions initiated by overactive Wnt/β-catenin signalling
- Creator: Goad, Jyoti , Ko, Yi-An , Kumar, Manish , Jamaluddin, M. Fairuz B. , Tanwar, Pradeep S.
- Resource Type: journal article
- Date: 2018
Proteomic characterization of the extracellular matrix of human uterine fibroids
- Creator: Jamaluddin, M. Fairuz B. , Nahar, Pravin , Tanwar, Pradeep S.
- Resource Type: journal article
- Date: 2018
Proteomic profiling of human uterine fibroids reveals upregulation of the extracellular matrix protein periostin
- Creator: Jamaluddin, M. Fairuz B. , Ko, Yi-An , Scott, Rodney J. , Nahar, Pravin , Tanwar, Pradeep S. , Kumar, Manish , Brown, Yazmin , Bajwa, Preety , Nagendra, Prathima B. , Skerrett-Byrne, David A. , Hondermarck, Hubert , Baker, Mark A. , Dun, Matthew D.
- Resource Type: journal article
- Date: 2018