Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness
- Creator: Bigdeli, Tim B. , Ripke, Stephan , Kirov, George , McQuillin, Andrew , Gurling, Hugh , Rujescu, Dan , Andreassen, Ole A. , Werge, Thomas , Blackwood, Douglas H. R. , Pato, Carlos N. , Pato, Michele T. , Malhotra, Anil K. , Bacanu, Silviu-Alin , O'Donovan, Michael C. , Kendler, Kenneth S. , Fanous, Ayman H. , Schizophrenia Working Group of the Psychiatric Genomics Consortium, , Henskens, Frans A. , Lee, Sang Hong , Wray, Naomi R. , Gejman, Pablo V. , Rietschel, Marcella , Cichon, Sven , St Clair, David , Corvin, Aiden
- Resource Type: journal article
- Date: 2016
LD score regression distinguishes confounding from polygenicity in genome-wide association studies
- Creator: Bulik-Sullivan, Brendan K. , Albus, M , Alexander, M , Amin, F , Bacanu, SA , Begemann, M , Belliveau, RA , Bene, J , Bergen, SE , Bruggeman, R , Bevilacqua, E , Bigdeli, TB , Black, DW , Buccola, NG , Buckner, RL , Byerley, W , Cahn, W , Cai, G , Cairns, MJ , Campion, D , Cantor, RM , Carr, VJ , Carrera, N , Catts, SV , Chambert, KD , Chan, RCK , Chen, RYL , Cohen, D , Chen, EYH , Cheng, W , Cheung, EFC , Chong, SA , Cloninger, CR , Cohen, N , Cormican, P , Craddock, N , Crespo-Facorro, B , Crowley, JJ , Curtis, D , Davidson, M , Davis, KL , Degenhardt, F , Del Favero, J , Loh, Po-Ru , Michie, Patricia T. , Schall, Ulrich , Scott, Rodney J. , Tooney, Paul A. , Wu, Jing Qin , Patterson, Nick , Daly, Mark J. , Price, Alkes L. , Neale, Benjamin M. , Finucane, Hilary K. , Ripke, Stephan , Yang, Jian , Schizophrenia Working Group of the Psychiatric Genomics Consortium, , Cairns, Murray J. , Henskens, Frans A. , Kelly, Brian J. , Loughland, Carmel M.
- Resource Type: journal article
- Date: 2015
Partitioning heritability by functional annotation using genome-wide association summary statistics
- Creator: Finucane, Hilary K. , Bulik-Sullivan, Brendan , Ripke, Stephan , Day, Felix R. , ReproGen Consortium, , Schizophrenia Working Group of the Psychiatric Genomics Consortium, , The RACI Consortium, , Purcell, Shaun , Stahl, Eli , Lindstrom, Sara , Perry, John R. B. , Okada, Yukinori , Gusev, Alexander , Raychaudhuri, Soumya , Daly, Mark J. , Patterson, Nick , Neale, Benjamin M. , Price, Alkes L. , Henskens, Frans A. , Loughland, Carmel M. , Michie, Patricia T. , Schall, Ulrich , Scott, Rodney J. , Trynka, Gosia , Tooney, Paul A. , Wu, Jing Qin , Reshef, Yakir , Loh, Po-Ru , Anttila, Verneri , Xu, Han , Zang, Chongzhi , Farh, Kyle
- Resource Type: journal article
- Date: 2015
A polygenic resilience score moderates the genetic risk for schizophrenia: Replication in 18,090 cases and 28,114 controls from the Psychiatric Genomics Consortium
- Creator: Hess, Jonathan L. , Mattheisen, Manuel , Henskens, Frans A. , Kelly, Brian J. , Loughland, Carmel M. , Michie, Patricia T. , Schall, Ulrich , Scott, Rodney J. , Tooney, Paul A. , Schizophrenia Working Group of the Psychiatric Genomics Consortium, , Greenwood, Tiffany A. , Tsuang, Ming T. , Edenberg, Howard J. , Holmans, Peter , Faraone, Stephen V. , Glatt, Stephen J. , Cairns, Murray J.
- Resource Type: journal article
- Date: 2023
No reliable association between runs of homozygosity and schizophrenia in a well-powered replication study
- Creator: Johnson, Emma C. , Bjelland, Douglas W. , Genovese, Giulio , Heilmann-Heimbach, Stefanie , Herms, Stefan , Hoffman, Per , Maier, Wolfgang , Mattheisen, Manuel , Morris, Derek , Mowry, Bryan , Müller-Mhysok, Betram , Neale, Benjamin , Howrigan, Daniel P. , Schizophrenia Working Group of the Psychiatric Genomics Consortium, , Carr, Vaughan J. , Henskens , Frans A. , Loughland, Carmel M. , Schall, Ulrich , Scott, Rodney J. , Abdellaoui, Abdel , Breen, Gerome , Borglum, Anders , Cichon, Sven , Degenhardt, Franziska , Forstner, Andreas J. , Frank, Josef
- Resource Type: journal article
- Date: 2016
Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis
- Creator: Loh, Po-Ro , Bhatia, Gaurav , Kendler, Kenneth S. , O'Donovan, Michael , Neale, Benjamin M. , Patterson, Nick , Price, Alkes L. , Henskens, Frans A. , Loughland, Carmel M. , Michie, Patricia T. , Schall, Ulrich , Scott, Rodney J. , Gusev, Alexander , Tooney, Paul A. , Wu, Jing Qin , Finucane, Hilary K. , Bulik-Sullivan, Brendan K. , Pollack, Samuela J. , Schizophrenia Working Group of the Psychiatric Genomics Consortium, , de Candia, Teresa R. , Lee, Sang Hong , Wray, Naomi R.
- Resource Type: journal article
- Date: 2015
Genetic correlation between amyotrophic lateral sclerosis and schizophrenia
- Creator: McLaughlin, Russell L. , Schijven, Dick , Schall, Ulrich , Scott, Rodney J. , van Rheenen, Wouter , van Eijk, Kristel R. , O'Brien, Margaret , Project MinE GWAS Consortium, , Schizophrenia Working Group of the Psychiatric Genomics Consortium, , Henskens, Frans A. , Loughland, Carmel M. , Michie, Patricia T. , Khan, René S. , Ophoff, Roel A. , Goris, An , Bradley, Daniel G. , Al-Chalabi, Ammar , van den Berg, Leonard H. , Luykx, Jurjen J.
- Resource Type: journal article
- Date: 2017
Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk
- Creator: Pouget, Jennie G. , Schizophrenia Working Group of the Psychiatric Genomics Consortium, , Martin, Javier , Mayes, Maureen D. , Bossini-Castillo, Lara , López-Isac, Elena , Jin, Ying , Santorico, Stephanie A. , Spritz, Richard A. , Hakonarson, Hakon , Polychronakos, Constantin , Raychaudhuri, Soumya , Han, Buhm , Knight, Jo , Cairns, Murray , Henskens, Frans A. , Kelly, Brian J. , Loughland, Carrmel M. , Michie, Patricia T. , Schall, Ulrich A. , Scott, Rodney , Tooney, Paul A. , Wu, Yang , Mignot, Emmanuel , Ollila, Hanna M. , Barker, Jonathan , Spain, Sarah , Dand, Nick , Trembath, Richard
- Resource Type: journal article
- Date: 2019
Schizophrenia risk from complex variation of complement component 4
- Creator: Sekar, Aswin , Bialas, Allison R. , Genovese, Giulio , Rose, Samuel A. , Handsaker, Robert E. , Schizophrenia Working Group of the Psychiatric Genomics Consortium, , Daly, Mark J. , Carroll, Michael C. , Stevens, Beth , McCarroll, Steven A. , Tooney, Paul A. , Henskens, Frans A. , de Rivera, Heather , Michie, Patricia , Schall, Ulrich , Loughland, Carmel , Cairns, Murray J. , Kelly, Brian J. , Scott, Rodney , Davis, Avery , Hammond, Timothy R. , Kamitaki, Nolan , Tooley, Katherine , Presumey, Jessy , Baum, Matthew , Van Doren, Vanessa
- Resource Type: journal article
- Date: 2016
Genetic markers of human evolution are enriched in schizophrenia
- Creator: Srinivasan, Saurabh , Bettella, Francesco , Mattingsdal, Morten , Wang, Yunpeng , Witoelar, Aree , Schork, Andrew J. , Thompson, Wesley K. , Zuber, Verena , Schizophrenia Working Group of the Psychiatric Genomics Consortium, , International Headache Genetics Consortium , Winsvold, Bendik S. , Zwart, John-Anker , Collier, David A. , Desikan, Rahul S. , Melle, Ingrid , Werge, Thomas , Dale, Anders M. , Djurovic, Srdjan , Andreassen, Ole A. , Henskens, Frans A. , Cairns, Murray J. , Kelly, Brian J. , Loughland, Carmel M. , Schall, Ulrich , Tooney, Paul A. , Mitchie, Patricia T. , Scott, Rodney J.
- Resource Type: journal article
- Date: 2016
Modeling linkage disequilibrium increases accuracy of polygenic risk scores
- Creator: Vilhjálmsson, Bjarni J. , Yang, Jian , Hayeck, Tristan , Won, Hong-Hee , Schizophrenia Working Group of the Psychiatric Genomics Consortium, , Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE) study, , Finucane, Hilary K. , Gusev, Alexander , Lindström, Sara , Ripke, Stephan , Genovese, Giulio , Loh, Po-Ru , Bhatia, Gaurav , Do, Ron
- Resource Type: journal article
- Date: 2015