Ablation of the canonical testosterone production pathway via knockout of the steroidogenic enzyme HSD17B3, reveals a novel mechanism of testicular testosterone production
- Creator: Rebourcet, Diane , Mackay, Rosa , Darbey, Annalucia , Curley, Michael K. , Jørgensen, Anne , Frederiksen, Hanne , Mitchell, Rod T. , O'Shaughnessy, Peter J. , Nef, Serge , Smith, Lee B.
- Resource Type: journal article
- Date: 2020
Deciphering cell lineage specification during male sex determination with single-cell RNA sequencing
- Creator: Stévant, Isabelle , Neirijnck, Yasmine , Borel, Christelle , Escoffier, Jessica , Smith, Lee B. , Antonarakis, Stylianos E. , Dermitzakis, Emmanouil T. , Nef, Serge
- Resource Type: journal article
- Date: 2018
Insulin and IGF1 receptors are essential for the development and steroidogenic function of adult Leydig cells
- Creator: Neirijnck, Yasmine , Calvel, Pierre , Smith, Lee B. , Nef, Serge , Kilcoyne, Karen R. , Kühne, Françoise , Stévant, Isbelle , Griffeth, Richard J. , Pitetti, Jean-Lüc , Andric, Silvana A. , Hu, Meng-Chun , Pralong, François
- Resource Type: journal article
- Date: 2018
Sertoli cell number defines and predicts germ and Leydig cell population sizes in the adult mouse testis
- Creator: Rebourcet, Diane , Darbey, Annalucia , Monteiro, Ana , Soffientini, Ugo , Tsai, Yi Ting , Handel, Ian , Pitetti, Jean-Luc , Nef, Serge , Smith, Lee B. , O'Shaughnessy, Peter J.
- Resource Type: journal article
- Date: 2017
Specific Transcriptomic Signatures and Dual Regulation of Steroidogenesis Between Fetal and Adult Mouse Leydig Cells
- Creator: Sararols, Pauline , Stevant, Isabelle , Neirijnck, Yasmine , Rebourcet, Diane , Darbey, Annalucia , Curley, Michael K. , Kuhne, Francoise , Dermitzakis, Emmanouil , Smith, Lee B. , Nef, Serge
- Resource Type: journal article
- Date: 2021