2,3-Dihydroquinazolin-4(1H)-ones and quinazolin-4(3H)-ones as broad-spectrum cytotoxic agents and their impact on tubulin polymerisation
- Creator: O'Brien, Nicholas S. , Gilbert, Jayne , McCluskey, Adam , Sakoff, Jennette A.
- Resource Type: journal article
- Date: 2024
Expansion of a Synthesized Library of N-Benzyl Sulfonamides Derived from an Indole Core to Target Pancreatic Cancer
- Creator: Hopkins, Megan D. , Costello, Ian J. , Chiew, Beatrice , McCluskey, Adam , Sheaff, Robert J. , Lamar, Angus A. , Brandeburg, Zachary C. , Slay, Emily L. , Zanders, Levi A. , Dunn, Caroline E. , Derewonko, Carina A. , Davitt, Colin L. , Reeder, Madison A. , Prichard, Kate
- Resource Type: journal article
- Date: 2023
Molecular Imprinting of Benzylpiperazine: A Comparison of the Self-Assembly and Semi-Covalent Approaches
- Creator: Wright, Kathleen M. , Bowyer, Michael C. , McCluskey, Adam , Holdsworth, Clovia I.
- Resource Type: journal article
- Date: 2023
Novel piperazine-1,2,3-triazole leads for the potential treatment of pancreatic cancer
- Creator: Sun, Jufeng , Baker, Jennifer R. , Russell, Cecilia C. , Pham, Hong N. T. , Goldsmith, Chloe D. , Cossar, Peter J. , Sakoff, Jennette A. , Scarlett, Christopher J. , McCluskey, Adam
- Resource Type: journal article
- Date: 2023
Systematic literature review reveals suboptimal use of chemical probes in cell-based biomedical research
- Creator: Sterling, Jayden , Baker, Jennifer R. , McCluskey, Adam , Munoz, Lenka
- Resource Type: journal article
- Date: 2023
The sulfonadyns: a class of aryl sulfonamides inhibiting dynamin I GTPase and clathrin mediated endocytosis are anti-seizure in animal models
- Creator: Odell, Luke R. , Jones, Nigel C. , Daniel, James A. , Gorgani, Nick N. , O'Brien, Terence J. , Robinson, Phillip J. , McCluskey, Adam , Chau, Ngoc , Robertson, Mark J. , Ambrus, Joseph I. , Deane, Fiona M. , Young, Kelly A. , Whiting, Ainslie , Xue, Jing , Prichard, Kate
- Resource Type: journal article
- Date: 2023
Wiskostatin and other carbazole scaffolds as off target inhibitors of dynamin I GTPase activity and endocytosis
- Creator: Cossar, Peter J. , Cardoso, David , McCluskey, Adam , Mathwin, Daniel , Russell, Cecilia C. , Chiew, Beatrice , Hamilton, Michael P. , Baker, Jennifer R. , Young, Kelly A. , Chau, Ngoc , Robinson, Phillip J.
- Resource Type: journal article
- Date: 2023
3,5-Bis(trifluoromethyl)phenylsulfonamides, a novel pancreatic cancer active lead. Investigation of the terminal aromatic moiety
- Creator: Sun, Jufeng , Ambrus, Joey I. , Baker, Jennifer R. , Russell, Cecilia C. , Cossar, Peter J. , Sakoff, Jennette A. , Scarlett, Christopher J. , McCluskey, Adam
- Resource Type: journal article
- Date: 2022
Amino Alcohols as Potential Antibiotic and Antifungal Leads
- Creator: Baker, Jennifer R. , Cossar, Peter J. , Blaskovich, Mark A. T. , Elliott, Alysha G. , Zuegg, Johannes , Cooper, Matthew A. , Lewis, Peter J. , McCluskey, Adam
- Resource Type: journal article
- Date: 2022
Antigiardial Activity of Novel Guanidine Compounds
- Creator: Stevens, Andrew J. , Abraham, Rebecca , Young, Kelly A. , Russell, Cecilia C. , McCluskey, Siobhann N. , Baker, Jennifer R. , Rusdi, Bertha , Page, Stephen W. , O'Handley, Ryan , O'Dea, Mark , Abraham, Sam , McCluskey, Adam
- Resource Type: journal article
- Date: 2022
Impact of a Novel Anticoccidial Analogue on Systemic Staphylococcus aureus Infection in a Bioluminescent Mouse Model
- Creator: Nguyen, Hang Thi , Venter, Henrietta , Woolford, Lucy , Young, Kelly , McCluskey, Adam , Garg, Sanjay , Page, Stephen W. , Trott, Darren J. , Ogunniyi, Abiodun D.
- Resource Type: journal article
- Date: 2022
In Vitro Activity of Robenidine Analogues NCL259 and NCL265 against Gram-Negative Pathogens
- Creator: Pi, Hongfei , Venter, Henrietta , Russell, Cecilia C. , Young, Kelly A. , McCluskey, Adam , Page, Stephen W. , Ogunniyi, Abiodum D. , Trott, Darren J.
- Resource Type: journal article
- Date: 2022
Light-mediated multi-target protein degradation using arylazopyrazole photoswitchable PROTACs (AP-PROTACs)
- Creator: Zhang, Qisi , Kounde, Cyrille S. , De Vita, Elena , Kozakov, Dima , McCluskey, Adam , Harling, John D. , Fuchter, Matthew J. , Tate, Edward W. , Mondal, Milon , Greenfield, Jake L. , Baker, Jennifer R. , Kotelnikov, Sergei , Ignatov, Mikhail , Tinworth, Christopher P. , Zhang, Leran , Conole, Daniel
- Resource Type: journal article
- Date: 2022
Prodrugs of the Archetypal Dynamin Inhibitor Bis-T-22
- Creator: Odell, Luke R. , Robertson, Mark J. , Young, Kelly A. , McGeachie, Andrew B. , Quan, Annie , Robinson, Phillip J. , McCluskey, Adam
- Resource Type: journal article
- Date: 2022
Pyrimidyn-Based Dynamin Inhibitors as Novel Cytotoxic Agents
- Creator: Odell, Luke R. , Chau, Ngoc , Russell, Cecilia C. , Young, Kelly A. , Gilbert, Jayne , Robinson, Phillip J. , Sakoff, Jennette A. , McCluskey, Adam
- Resource Type: journal article
- Date: 2022
Role of Clathrin and Dynamin in Clathrin Mediated Endocytosis/Synaptic Vesicle Recycling and Implications in Neurological Diseases
- Creator: Prichard, Kate L. , O'Brien, Nicholas S. , Murcia, Sari R. , Baker, Jennifer R. , McCluskey, Adam
- Resource Type: journal article
- Date: 2022
Amino alcohol acrylonitriles as broad spectrum and tumour selective cytotoxic agents
- Creator: Baker, Jennifer R. , Russell, Cecilia C. , Gilbert, Jayne , McCluskey, Adam , Sakoff, Jennette A.
- Resource Type: journal article
- Date: 2021
Comparison of two transmission electron microscopy methods to visualize drug-induced alterations of gram-negative bacterial morphology
- Creator: Nguyen, Hang Thi , O'Donovan, Lisa A. , Venter, Henrietta , Russell, Cecilia C. , McCluskey, Adam , Page, Stephen W. , Trott, Darren J. , Ogunniyi, Abiodun D.
- Resource Type: journal article
- Date: 2021
Cytotoxic 1,2,3-Triazoles as Potential Leads Targeting the S100A2-p53 Complex: Synthesis and Cytotoxicity
- Creator: Sun, Jufeng , Baker, Jennifer R. , Russell, Cecilia C. , Cossar, Peter J. , Ngoc Thuy Pham, Hong , Sakoff, Jennette A. , Scarlett, Christopher J. , McCluskey, Adam
- Resource Type: journal article
- Date: 2021
Development and interpretation of a QSAR model for in vitro breast cancer (MCF-7) cytotoxicity of 2-phenylacrylonitriles
- Creator: Stanton, David T. , Baker, Jennifer R. , McCluskey, Adam , Paula, Stefan
- Resource Type: journal article
- Date: 2021