Regulation of ryanodine receptors by calsequestrin: effect of high luminal Ca²⁺ and phosphorylation
- Creator: Beard, Nicole A. , Casarotto, Marco G. , Wei, Lan , Varsanyi, Magdolna , Laver, Derek R. , Dulhunty, Angela F.
- Resource Type: journal article
- Date: 2005
Protein interactions involving the γ2 large cytoplasmic loop of GABAA receptors modulate conductance
- Creator: Everitt, Andrea B. , Seymour, Victoria A. L. , Curmi, John , Laver, Derek R. , Gage, Peter W. , Tierney, M. Louise
- Resource Type: journal article
- Date: 2009
ent-Verticilide B1 Inhibits Type 2 Ryanodine Receptor Channels and is Antiarrhythmic in Casq2-/- MiceS
- Creator: Gochman, Aaron , Do, Tri Q. , Cornea, Razvan L. , Laver, Derek R. , Johnston, Jeffrey N. , Knollmann, Bjorn C. , Kim, Kyungsoo , Schwarz, Jacob A. , Thorpe, Madelaine P. , Blackwell, Daniel J. , Ritschel, Paxton A. , Smith, Abigail N. , Rebbeck, Robyn T. , Akers, Wendell S.
- Resource Type: journal article
- Date: 2024
SR Ca²⁺ store refill-a key factor in cardiac pacemaking
- Creator: Imtiaz, Mohammad S. , von der Weid, Pierre-Yves , Laver, Derek R. , van Helden, Dirk F.
- Resource Type: journal article
- Date: 2010
Extraction of sub-microscopic Ca fluxes from blurred and noisy fluorescent indicator images with a detailed model fitting approach
- Creator: Kong, Cherrie H. T. , Laver, Derek R. , Cannell, Mark B.
- Resource Type: journal article
- Date: 2013
RYR2 channel inhibition is the principal mechanism of flecainide action in CPVT
- Creator: Kryshtal, Dmytro O. , Blackwell, Daniel J. , Egly, Christian L. , Smith, Abigail N. , Batiste, Suzanne M. , Johnston, Jeffrey N. , Laver, Derek R. , Knollmann, Bjorn C.
- Resource Type: journal article
- Date: 2021
Ca²⁺ stores regulate ryanodine receptor Ca²⁺ release channels via luminal and cytosolic Ca²⁺ sites
- Creator: Laver, Derek R.
- Resource Type: journal article
- Date: 2007
Disulfonic stilbene permeation and block of the anion channel from the sarcoplasmic reticulum of rabbit skeletal muscle
- Creator: Laver, Derek R. , Bradley, Katherine M.
- Resource Type: journal article
- Date: 2006
Luminal Ca²⁺ activation of cardiac ryanodine receptors by luminal and cytoplasmic domains
- Creator: Laver, Derek R.
- Resource Type: journal article
- Date: 2009
The ryanodine receptor pore blocker neomycin also inhibits channel activity via a previously undescribed high-affinity Ca²⁺ binding site
- Creator: Laver, Derek R. , Hamada, Tomoyo , Fessenden, James D. , Ikemoto, Noriaki
- Resource Type: journal article
- Date: 2007
Ca²⁺ stores regulate ryanodine receptor Ca²⁺ release channels via luminal and cytosolic Ca²⁺ sites
- Creator: Laver, Derek R.
- Resource Type: journal article
- Date: 2007
Regulation of RyR Channel Gating by Ca²⁺, Mg²⁺ and ATP
- Creator: Laver, Derek R.
- Resource Type: book chapter
- Date: 2010
Luminal Mg²⁺, a key factor controlling RYR2-mediated Ca²⁺ release: cytoplasmic and luminal regulation modeled in a tetrameric channel
- Creator: Laver, Derek R. , Honen, Bonny N.
- Resource Type: journal article
- Date: 2008
Cardiac calcium release channel (ryanodine receptor 2) regulation by halogenated anesthetics
- Creator: Laver, Derek R. , Attia, John , Oldmeadow, Christopher , Quail, Anthony W.
- Resource Type: journal article
- Date: 2017
A domain peptide of the cardiac ryanodine receptor regulates channel sensitivity to luminal Ca²⁺ via cytoplasmic Ca²⁺ sites
- Creator: Laver, Derek R. , Honen, Bonny N. , Lamb, Graham D. , Ikemoto, Noriaki
- Resource Type: journal article
- Date: 2008
Regulation of the RyR channel gating by Ca²⁺ and Mg²⁺
- Creator: Laver, Derek R.
- Resource Type: journal article
- Date: 2018
Coupled calcium release channels and their regulation by luminal and cytosolic ions
- Creator: Laver, Derek R.
- Resource Type: journal article
- Date: 2005
Three independent mechanisms contribute to tetracaine inhibition of cardiac calcium release channels
- Creator: Laver, Derek R. , van Helden , Dirk F.
- Resource Type: journal article
- Date: 2011
Luminal Ca²⁺-regulated Mg²⁺ inhibition of skeletal RyRs reconstituted as isolated channels or coupled clusters
- Creator: Laver, Derek R. , O'Neill, Erin R. , Lamb, Graham D.
- Resource Type: journal article
- Date: 2004
Beta-adrenergic stimulation increases RyR2 activity via intracellular Ca²⁺ and Mg²⁺ regulation
- Creator: Li, Jiao , Imtiaz, Mohammad S. , Beard, Nicole A. , Dulhunty, Angela F. , Thorn, Rick , van Helden Dirk F. , Laver, Derek R.
- Resource Type: journal article
- Date: 2013