The BH3-mimetic ABT-737 sensitizes human melanoma cells to apoptosis induced by selective BRAF inhibitors but does not reverse acquired resistance
- Creator: Wroblewski, David , Mijatov, Branka , Mohana-Kumaran, Nethia , Lai, Fritz , Gallagher, Stuart J. , Haass, Nikolas K. , Zhang, Xu Dong , Hersey, Peter
- Resource Type: journal article
- Date: 2013
RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy
- Creator: Luan, Qi , Jin, Lei , Tseng, Hsin-Yi , Zhang, Xu Dong , Jiang, Chen Chen , Tay, Kwang Hong , Lai, Fritz , Liu, Xiao Ying , Liu, Yi Lun , Guo, Su Tang , Li, Chung Ying , Yan, Xu Guang
- Resource Type: journal article
- Date: 2015
Noxa upregulation by oncogenic activation of MEK/ERK through CREB promotes autophagy in human melanoma cells
- Creator: Liu, Yi Lun , Lai, Fritz , Jin, Lei , Zhang, Xu Dong , Wilmott, James S. , Yan, Xu Guang , Liu, Xiao Ying , Luan, Qi , Guo, Su Tang , Jiang, Chen Chen , Tseng, Hsin-Yi , Scolyer, Richard A.
- Resource Type: journal article
- Date: 2014
RIP1 kinase is an oncogenic driver in melanoma
- Creator: Liu, Xiao Ying , Lai, Fritz , Jin, Lei , Zhang, Xu Dong , Yan, Xu Guang , Jiang, Chen Chen , Guo, Su Tang , Wang, Chun Yan , Croft, Amanda , Tseng, Hsin-Yi , Wilmott, James S. , Scolyer, Richard A.
- Resource Type: journal article
- Date: 2015
RIP1 protects melanoma cells from apoptosis induced by BRAF/MEK inhibitors
- Creator: Lei, Fu Xi , Jin, Lei , Liu, Xiao Ying , Lai, Fritz , Yan, Xu Guang , Farrelly, Margaret , Guo, Su Tang , Zhao, Xin Han , Zhang, Xu Dong
- Resource Type: journal article
- Date: 2018
Histone deacetylases (HDACs) as mediators of resistance to apoptosis in melanoma and as targets for combination therapy with selective BRAF inhibitors
- Creator: Lai, Fritz , Jin, Lei , Gallagher, Stuart , Mijatov, Branka , Zhang, Xu Dong , Hersey, Peter
- Resource Type: book chapter
- Date: 2012
Evidence for upregulation of Bim and the splicing factor SRp55 in melanoma cells from patients treated with selective BRAF inhibitors
- Creator: Lai, Fritz , Jiang, Chen Chen , Farrelly, Margaret L. , Zhang, Xu Dong , Hersey, Peter
- Resource Type: journal article
- Date: 2012
MEK-independent survival of B-RAFV600E melanoma cells selected for resistance to apoptosis induced by the RAF inhibitor PLX4720
- Creator: Jiang, Chen Chen , Lai, Fritz , Thorne, Rick F. , Yang, Fan , Liu, Hao , Hersey, Peter , Zhang, Xu Dong
- Resource Type: journal article
- Date: 2011
Oncogenic activation of MEK/ERK primes melanoma cells for adaptation to endoplasmic reticulum stress
- Creator: Croft, Amanda , Tay, Kwang H. , Zhang, Xu D. , Boyd, Suzanah C. , Guo, Su T. , Jiang, Chen C. , Lai, Fritz , Tseng, Hsin-Yi , Jin, Lei , Rizos, Helen , Hersey, Peter
- Resource Type: journal article
- Date: 2014