A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis
- Creator: Beckett, Emma L. , Stevens, Richard L. , Oliver, Brian G. , van Rooijen, Nico , Inman, Mark D. , Adachi, Roberto , Soberman, Roy J. , Hamadi, Sahar , Wark, Peter A. , Foster, Paul S. , Hansbro, Philip M. , Jarnicki, Andrew G. , Kim, Richard Y. , Hanish, Irwan , Hansbro, Nicole G. , Deane, Andrew , Keely, Simon , Horvat, Jay C. , Yang, Ming
- Resource Type: journal article
- Date: 2013
Abnormal M1/M2 macrophage phenotype profiles in the small airway wall and lumen in smokers and chronic obstructive pulmonary disease (COPD)
- Creator: Eapen, Mathew Suji , Hansbro, Philip M. , McAlinden, Kielan , Kim, Richard Y. , Ward, Chris , Hackett, Tillie-Louise , Walters, Eugene H. , Sohal, Sukhwinder Singh
- Resource Type: journal article
- Date: 2017
Airway and parenchyma transcriptomics in a house dust mite model of experimental asthma
- Creator: Tu, Xiaofan , Gomez, Henry M. , Donovan, Chantal , Kim, Richard Y. , Brown, Alexandra C. , de Jong, Emma , Galvao, Izabela , Faiz, Alen , Bosco, Anthony , Horvat, Jay C. , Hansbro, Philip
- Resource Type: journal article
- Date: 2023
Airway and parenchymal transcriptomics in a novel model of asthma and COPD overlap
- Creator: Tu, Xiaofan , Kim, Richard Y. , Loering, Svenja , Nguyen, Duc H. , Nair, Prema Mono , Haw, Tatt Jhong , Alemao, Charlotte A. , Faiz, Alen , Tay, Hock L. , Wark, Peter A. B. , Knight, Darryl A. , Foster, Paul S. , Brown, Alexandra C. , Bosco, Anthony , Horvat, Jay C. , Hansbro, Philip M. , Donovan, Chantal , de Jong, Emma , Jones-Freeman, Bernadette , Ali, Md Khadem , Gomez, Henry M. , Budden, Kurtis F. , Starkey, Malcolm R. , Cameron, Guy J. M.
- Resource Type: journal article
- Date: 2022
Asthma-COPD overlap: current understanding and the utility of experimental models
- Creator: Tu, Xiaofan , Donovan, Chantal , Kim, Richard Y. , Wark, Peter A. B. , Horyat, Jay C. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2021
Cellular mechanisms underlying steroid-resistant asthma
- Creator: Wadhwa, Ridhima , Dua, Kamal , Adcock, Ian M. , Horvat, Jay C. , Kim, Richard Y. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2019
Chlamydia muridarum lung infection in infants alters hematopoietic cells to promote allergic airway disease in mice
- Creator: Starkey, Malcolm R. , Kim, Richard Y. , Horvat, Jay C. , Hansbro, Philip M. , Idzco, Marco , Beckett, Emma L. , Schilter, Heidi C. , Shim, Doris , Essilfie, Ama-Tawiah , Nguyen, Duc H. , Beagley, Kenneth W. , Joerg, Mattes , Mackay, Charles R.
- Resource Type: journal article
- Date: 2012
Chlamydial respiratory infection during allergen sensitization drives neutrophilic allergic airways disease
- Creator: Horvat, Jay C. , Starkey, Malcolm R. , Kim, Richard Y. , Beagley, Kenneth W. , Preston, Julie A. , Gibson, Peter G. , Foster, Paul S. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2010
Chronic cigarette smoke exposure induces systemic hypoxia that drives intestinal dysfunction
- Creator: Fricker, Michael , Goggins, Bridie J. , Talley, Nicholas J. , Walker, Marjorie M. , Keely, Simon , Hansbro, Philip M. , Mateer, Sean , Jones, Bernadette , Kim, Richard Y. , Gellatly, Shaan L. , Jarnicki, Andrew G. , Powell, Nicholas , Oliver, Brian G. , Radford-Smith, Graham
- Resource Type: journal article
- Date: 2018
Critical role for iron accumulation in the pathogenesis of fibrotic lung disease
- Creator: Ali, Md Khadem , Kim, Richard Y. , Borghuis, Theo , Karim, Rafia , Pinkerton, James W. , Aryal, Ritambhara , Heidari, Moones , Martin, Kristy L. , Burgess, Janette K. , Oliver, Brian G. , Trinder, Debbie , Johnstone, Daniel M. , Brown, Alexandra C. , Milward, Elizabeth A. , Hansbro, Philip M. , Horvat, Jay C. , Donovan, Chantal , Vanka, Kanth S. , Mayall, Jemma R. , Liu, Gang , Pillar, Amber L. , Jones-Freeman, Bernadette , Xenaki, Dikaia
- Resource Type: journal article
- Date: 2020
Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma
- Creator: Ali, Md Khadem , Kim, Richard Y. , Donovan, Chantal , Pathinayake, Prabuddha S. , Carroll, Olivia R. , Trinder, Debbie , Tay, Hock L. , Badi, Yusef E. , Kermani, Nazanin Z. , Guo, Yi-Ke , Aryal, Ritambhara , Mumby, Sharon , Brown, Alexandra C. , Pavlidis, Stelios , Adcock, IM , Weaver, Jessica , Xenaki, D , Oliver, BG , Holliday, Elizabeth G. , Foster, Peter S. , Wark, Peter A. , Johnstone, DM , Milward, EA , Mayall, Jemma R. , Hansbro, Philip M. , Horvat, Jay C. , Karim, Rafia , Pinkerton, James W. , Liu, Gang , Martin, Kristy L. , Starkey, Malcolm R. , Pillar, Amber L.
- Resource Type: journal article
- Date: 2020
Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease
- Creator: Bowerman, Kate L. , Rehman, Saima Firdous , Yang, Ian A. , Wark, Peter A. , Hugenholtz, Philip , Hansbro, Philip M. , Vaughan, Annalicia , Lachner, Nancy , Budden, Kurtis F. , Kim, Richard Y. , Wood, David L. A. , Gellatly, Shaan L. , Shukla, Shakti D. , Wood, Lisa G.
- Resource Type: journal article
- Date: 2020
Early-life chlamydial lung infection enhances allergic airways disease through age-dependent differences in immunopathology
- Creator: Horvat, Jay C. , Starkey, Malcolm R. , Kim, Richard Y. , Phipps, Simon , Gibson, Peter G. , Beagley, Kenneth W. , Foster, Paul S. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2010
Elucidating novel disease mechanisms in severe asthma
- Creator: Kim, Richard Y. , Rae, Brittany , Neal, Rachel , Donovan, Chantal , Pinkerton, James , Balachandran, Lohis , Starkey, Malcolm R. , Knight, Darryl A. , Horvat, Jay C. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2016
Emerging therapeutic targets and preclinical models for severe asthma
- Creator: Galvao, Izabela , Kim, Richard Y. , Shen, Sijie , Budden, Kurtis F. , Vieira, Angélica T. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2020
Fibulin-1 regulates the pathogenesis of tissue remodeling in respiratory diseases
- Creator: Liu, Gang , Cooley, Marion A. , Tjin, Gavin , Wark, Peter A. B. , Walker, Marjorie M. , Horvat, Jay C. , Oliver, Brian G. , Argraves, W. Scott , Knight, Darryl A. , Burgess, Janette K. , Hansbro, Philip M. , Jarnicki, Andrew G. , Hsu, Alan C-Y. , Nair, Prema M. , Haw, Tatt Jhong , FRICKER, Michael , Gellatly, Shaan L. , Kim, Richard Y. , Inman, Mark D.
- Resource Type: journal article
- Date: 2016
Human beta-defensin-2 suppresses key features of asthma in murine models of allergic airways disease
- Creator: Pinkerton, James W. , Kim, Richard Y. , Nordkild, Peter , Horvat, Jay C. , Jensen, Benjanim A. H. , Wehkamp, Jan , Hansbro, Philip M. , Koeninger, Louis , Armbruster, Nicole S. , Hansbro, Nicole G. , Brown, Alexandra C. , Jayaraman, Ranjith , Shen, Sijie , Malek, Nisar , Cooper, Matthew A.
- Resource Type: journal article
- Date: 2020
IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis
- Creator: Starkey, Malcolm R. , Plank, Maximilian W. , Donovan, Chantal , Hansbro, Nicole G. , Nguyen, Duc H. , Nair, Prema Mono , Kim, Richard Y. , Horvat, Jay C. , Kaiko, Gerard E. , Durum, Scott K. , Wark, Peter A. , Sin, Don D. , Casolari, Paolo , Caramori, Gaetano , Adcock, Ian M. , Foster, Paul S. , Hansbro, Philip M. , Papi, Alberto , Pavlidis, Stelios , Guo, Yike , Cameron, Guy J. M. , Haw, Tatt Jhong , Tam, Anthony , Obiedat, Maen
- Resource Type: journal article
- Date: 2019
IL-6 drives neutrophil-mediated pulmonary inflammation associated with bacteremia in murine models of colitis
- Creator: Mateer, Sean W. , Mathe, Andrea , Kim, Richard Y. , Minahan, Kyra , Walker, Marjorie M. , Callister, Robert C. , Foster, Paul S. , Horvat, Jay C. , Hansbro, Philip M. , Keely, Simon , Bruce, Jessica , Liu, Gang , Maltby, Steven , Fricker, Michael , Goggins, Bridie J. , Tay, Hock L. , Marks, Ellen , Burns, Grace
- Resource Type: journal article
- Date: 2018
Inflammasomes in COPD and neutrophilic asthma
- Creator: Kim, Richard Y. , Pinkerton, James W. , Gibson, Peter G. , Cooper, Matthew A. , Horvat, Jay C. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2015