A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis
- Creator: Beckett, Emma L. , Stevens, Richard L. , Oliver, Brian G. , van Rooijen, Nico , Inman, Mark D. , Adachi, Roberto , Soberman, Roy J. , Hamadi, Sahar , Wark, Peter A. , Foster, Paul S. , Hansbro, Philip M. , Jarnicki, Andrew G. , Kim, Richard Y. , Hanish, Irwan , Hansbro, Nicole G. , Deane, Andrew , Keely, Simon , Horvat, Jay C. , Yang, Ming
- Resource Type: journal article
- Date: 2013
Maternal smoke exposure impairs the long-term fertility of a female offspring in a murine model
- Creator: Camlin, Nicole J. , Sobinoff, Alexander P. , Sutherland, Jessie M. , Beckett, Emma L. , Jarnicki, Andrew G. , Vanders, Rebecca L. , Hansbro, Philip M. , McLaughlin, Eileen A. , Holt, Janet E.
- Resource Type: journal article
- Date: 2016
Maternal smoke exposure impairs the long-term fertility of female offspring in a murine model
- Creator: Camlin, Nicole J. , Sobinoff, Alexander P. , Sutherland, Jessie M. , Beckett, Emma L. , Jarnicki, Andrew G. , Vanders, Rebecca L. , Hansbro, Philip M. , McLaughlin, Eileen A. , Holt, Janet E.
- Resource Type: journal article
- Date: 2016
Aim2 suppresses cigarette smoke-induced neutrophil recruitment, neutrophil caspase-1 activation and anti-Ly6G-mediated neutrophil depletion
- Creator: Donovan, Chantal , Kim, Richard Y , Khan, Haroon , Pickles, Sophie , Sahu, Priyanka , Chimankar, Vrushali , Tu, Xiaofan , Ali, Md Khadem , Mayall, Jemma R. , Nguyen, Duc H. , Budden, Kurtis F. , Kumar, Vinod , Galvao, Izabela , Wark, Peter A. B. , Horvat, Jay C. , Hansbro, Philip M. , Ab Wark, P , Oliver, BG , Horvat, JC , Hansbro, PM , Jarnicki, Andrew G. , Brown, Alexandra C. , Jones-Freeman, Bernadette , Gomez, Henry M. , Wadhwa, Ridhima , Hortle, Elinor , Jayaraman, Ranjith
- Resource Type: journal article
- Date: 2022
Identification and optimization of mechanism-based fluoroallylamine inhibitors of lysyl oxidase-like 2/3
- Creator: Findlay, Alison D. , Foot, Jonathan S. , Buson, Alberto , Deodhar, Mandar , Jarnicki, Andrew G. , Hansbro, Philip M. , Liu, Gang , Schilter, Heidi , Turner, Craig I. , Zhou, Wenbin , Jarolimek, Wolfgang
- Resource Type: journal article
- Date: 2019
The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.
- Creator: Franklin, Bernado S. , Bossaller, Lukas , Mangan, Matthew S. , Zimmer, Sebastian , Monks, Brian G. , Fricke, Martin , Schmidt, Reinhold E. , Espevik, Terje , Jones, Bernadette , Jarnicki, Andrew G. , Hansbro, Philip M. , Busto, Patricia , De Nardo, Dominic , Marshak-Rothstein, Ann , Hornemann, Simone , Aguzzi, Adriano , Kastenmüller, Wolfgang , Latz, Eicke , Ratter, Jacqueline M. , Stutz, Andrea , Engels, Gudrun , Brenker, Christoph , Nordhoff, Mark , Mirandola, Sandra R. , Al-Amoudi, Ashraf
- Resource Type: journal article
- Date: 2014
Chronic cigarette smoke exposure induces systemic hypoxia that drives intestinal dysfunction
- Creator: Fricker, Michael , Goggins, Bridie J. , Talley, Nicholas J. , Walker, Marjorie M. , Keely, Simon , Hansbro, Philip M. , Mateer, Sean , Jones, Bernadette , Kim, Richard Y. , Gellatly, Shaan L. , Jarnicki, Andrew G. , Powell, Nicholas , Oliver, Brian G. , Radford-Smith, Graham
- Resource Type: journal article
- Date: 2018
Macrolides for macrophages in chronic obstructive pulmonary disease
- Creator: Hansbro, Philip M. , Jarnicki, Andrew G.
- Resource Type: journal article
- Date: 2012
Importance of mast cell Prss31/transmembrane tryptase/tryptase-γ in lung function and experimental chronic obstructive pulmonary disease and colitis
- Creator: Hansbro, Philip M. , Hamilton, Matthew J. , Foster, Paul S. , Krilis, Steven A. , Stevens, Richard L. , Fricker, Michael , Gellatly, Shaan L. , Jarnicki, Andrew G. , Zheng, Dominick , Frei, Sandra M. , Wong, G. William , Hamadi, Sahar , Zhou, Saijun
- Resource Type: journal article
- Date: 2014
MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase-mediated suppression of histone deacetylase 2
- Creator: Kim, Richard Y. , Horvat, Jay C. , Sunkara, Krishna P. , Nguyen, Thi Hiep , Jarnicki, Andrew G. , Keely, Simon , Mattes, Joerg , Adcock, Ian M. , Foster, Paul S. , Hansbro, Philip M. , Pinkerton, James W. , Starkey, Malcolm R. , Essilfie, Ama T. , Mayall, Jemma R. , Nair, Prema M. , Hansbro, Nicole G. , Jones, Bernadette , Haw, Tatt Jhong
- Resource Type: journal article
- Date: 2017
microRNA-21-mediated SATB1/S100A9/NF-kappa B axis promotes chronic obstructive pulmonary disease pathogenesis
- Creator: Kim, Richard Y. , Sunkara, Krishna P. , Ricciardolo, Fabio L. M. , Di Stefano, Antonino , Haw, Tatt Jhong , Liu, Gang , Ferguson, Angela L. , Palendira, Umamainthan , Wark, Peter A. , Conickx, Griet , Mestdagh, Pieter , Brusselle, Guy G. , Bracke, Ken R. , Caramori, Gaetano , Foster, Paul S. , Horvat, Jay C. , Hansbro, Philip M. , Jarnicki, Andrew G. , Donovan, Chantal , Hsu, Alan C. , Ieni, Antonio , Beckett, Emma L. , Galvão, Izabela , Wijnant, Sara
- Resource Type: journal article
- Date: 2021
Airway remodelling and inflammation in asthma are dependent on the extracellular matrix protein fibulin-1c
- Creator: Liu, Gang , Cooley, Marion A. , Tay, Hock , Foster, Paul S. , Wark, Peter A. , Horvat, Jay C. , Bourke, Jane E. , Grainge, Chris L. , Argraves, W. Scott , Oliver, Brian G. , Knight, Darryl A. , Burgess, Janette K. , Nair, Prema M. , Hansbro, Philip M. , Donovan, Chantal , Hsu, Alan C. , Jarnicki, Andrew G. , Haw, Tatt Jhong , Hansbro, Nicole G. , Ge, Qi , Brown, Alexandra C.
- Resource Type: journal article
- Date: 2017
Fibulin-1c regulates transforming growth factor-beta activation in pulmonary tissue fibrosis
- Creator: Liu, Gang , Cooley, Marion A. , Jones, Berrnadette , Hansbro, Nicole G. , Wark, Peter A. , Horvat, Jay C. , Argraves, W. Scott , Oliver, Brian G. , Knight, Darryl A. , Burgess, Janette K. , Hansbro, Philip M. , Jarnicki, Andrew G. , Borghuis, Theo , Nair, Prema M. , Tjin, Gavin , Hsu, Alan C. , Haw, Tatt Jhong , Fricker, Michael , Harrison, Celeste L.
- Resource Type: journal article
- Date: 2019
Fibulin-1 regulates the pathogenesis of tissue remodeling in respiratory diseases
- Creator: Liu, Gang , Cooley, Marion A. , Tjin, Gavin , Wark, Peter A. B. , Walker, Marjorie M. , Horvat, Jay C. , Oliver, Brian G. , Argraves, W. Scott , Knight, Darryl A. , Burgess, Janette K. , Hansbro, Philip M. , Jarnicki, Andrew G. , Hsu, Alan C-Y. , Nair, Prema M. , Haw, Tatt Jhong , FRICKER, Michael , Gellatly, Shaan L. , Kim, Richard Y. , Inman, Mark D.
- Resource Type: journal article
- Date: 2016
Adverse roles of mast cell chymase-1 in chronic obstructive pulmonary disease
- Creator: Liu, Gang , Jarnicki, Andrew G. , Paudel, Keshav R. , Lu, Wenying , Wadhwa, Ridhima , Philp, Ashleigh M. , Van Eeckhoutte, Hannelore , Marshall, Jacqueline E. , Malyla, Vamshikrishna , Katsifis, Angelica , Fricker, Michael , Hansbro, Nicole G. , Dua, Kamal , Kermani, Nazanin Z. , Eapen, Mathew S. , Tiotiu, Angelica , Chung, K. Fan , Caramori, Gaetano , Bracke, Ken , Adcock, Ian M. , Wark, Peter A. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2022
Adverse roles of mast cell chymase-1 in COPD
- Creator: Liu, Gang , Jarnicki, Andrew G. , Fricker, Michael , Hansbro, Nicole G. , Dua, Kamal , Kermani, Nazanin Z. , Eapen, Mathew S. , Tiotiu, Angelica , Chung, K. Fan , Caramori, Gaetano , Bracke, Ken , Adcock, Ian M. , Paudel, Keshav R. , Sohal, Sukhwinder S. , Wark, Peter A. , Oliver, Brian G. , Hansbro, Philip M. , Lu, Wenying , Wadhwa, Ridhima , Philp, Ashleigh M. , Van Eeckhoutte, Hannelore , Marshall, Jacqueline E. , Malyla, Vamshikrishna , Katsifis, Angelica
- Resource Type: journal article
- Date: 2022
Mitochondrial DNA neutrophil extracellular traps are formed after trauma and subsequent surgery
- Creator: McIlroy, Daniel J. , Jarnicki, Andrew G. , Au, Gough G. , Lott, Natalie , Smith, Doug W. , Hansbro, Philip M. , Balogh, Zsolt J.
- Resource Type: journal article
- Date: 2014
Time-resolved proteomic profiling of cigarette smoke-induced experimental chronic obstructive pulmonary disease
- Creator: Skerrett-Byrne, David A. , Bromfield, Elizabeth G. , Anderson, Amanda L. , Nixon, Brett , Scott, Rodney J. , Wark, Peter A. B. , Dun, Matthew D. , Hansbro, Philip M. , Murray, Heather C. , Jamaluddin, M. Fairuz B. , Jarnicki, Andrew G. , Fricker, Michael , Essilfie, Ama T. , Jones, Bernadette , Haw, Tatt J. , Hampsey, Daniel
- Resource Type: journal article
- Date: 2021
TLR2, TLR4 AND MyD88 mediate allergic airway disease (AAD) and Streptococcus pneumoniae-induced suppression of AAD
- Creator: Thorburn, Alison N. , Tseng, Hsin-Yi , Donovan, Chantal , Hansbro, Nicole G. , Jarnicki, Andrew G. , Foster, Paul S. , Gibson, Peter G. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2016
Programming of formalin-induced nociception by neonatal LPS exposure: maintenance by peripheral and central neuroimmune activity
- Creator: Zouikr, Ihssane , Ahmed, Abdulrzag F. , Horvat, Jay C. , Beagley, Kenneith W. , Cllifton, Vicki L. , Ray, Allyson , Thorne, Rick F. , Jarnicki, Andrew G. , Hansbro, Philip M. , Hidgson, Deborah M.
- Resource Type: journal article
- Date: 2015