Antiviral Responses of Tissue-resident CD49a+ Lung Natural Killer Cells Are Dysregulated in Chronic Obstructive Pulmonary Disease
- Creator: Cooper, Grace E. , Mayall, Jemma , Khakoo, Salim I. , Wilkinson, Tom M. A. , Hansbro, Philip M. , Staples, Karl J. , Donovan, Chantal , Haw, Tatt J. , Budden, Kurtis F. , Hansbro, Nicole G. , Blomme, Evy E. , Maes, Tania , Kong, Chia Wei , Horvat, Jay C.
- Resource Type: journal article
- Date: 2023
RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD
- Creator: Van Eeckhoutte, Hannelore P. , Donovan, Chantal , Beal, Allison M. , Geddes, Brad , Bertin, John , Vanden Berghe, Tom , De Volder, Joyceline , Maes, Tania , Vandenabeele, Peter , Vanaudenaerde, Bart M. , Deforce, Dieter , Škevin, Sonja , Kim, Richard Y. , Van Nieuwerburgh, Filip , Verhamme, FM , Joos, GF , Idrees, S , Schiller, HB , Yildirim, AÖ , Faiz, A , Bertrand, MJM , Brusselle, GG , Hansbro, Philip M. , Conlon, Thomas M. , Bracke, KR , Ansari, Meshal , Khan, Haroon , Jayaraman, Ranjith , Hansbro, Nicole G. , Dondelinger, Yves , Delanghe, Tom
- Resource Type: journal article
- Date: 2023
Smoking and tetramer tryptase accelerate intervertebral disc degeneration by inducing METTL14-mediated DIXDC1 m6 modification
- Creator: Tu, Ji , Li, Wentian , Zou, Jun , Diwan, Ashish , Hansbro, Philip M. , Yan, Qi , Bai, Xupeng , Donovan, Chantal , Kim, Richard Y. , Galvao, Izabela , Das, Abhirup , Yang, Cao
- Resource Type: journal article
- Date: 2023
The Complex Association between COPD and COVID-19
- Creator: Awatade, Nikhil T. , Wark, Peter A. B. , Chan, Andrew S. L. , Mamun, SM Abdullah Al , Mohd Esa, Nurul Yaqueen , Matsunaga, Kazuto , Rhee, Chin Kook , Hansbro, Philip M. , Sohal, Sukhwinder Singh , On Behalf Of The Asian Pacific Society Of Respirology Apsr Copd Assembly,
- Resource Type: journal article
- Date: 2023
Adverse roles of mast cell chymase-1 in chronic obstructive pulmonary disease
- Creator: Liu, Gang , Jarnicki, Andrew G. , Paudel, Keshav R. , Lu, Wenying , Wadhwa, Ridhima , Philp, Ashleigh M. , Van Eeckhoutte, Hannelore , Marshall, Jacqueline E. , Malyla, Vamshikrishna , Katsifis, Angelica , Fricker, Michael , Hansbro, Nicole G. , Dua, Kamal , Kermani, Nazanin Z. , Eapen, Mathew S. , Tiotiu, Angelica , Chung, K. Fan , Caramori, Gaetano , Bracke, Ken , Adcock, Ian M. , Wark, Peter A. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2022
Aim2 suppresses cigarette smoke-induced neutrophil recruitment, neutrophil caspase-1 activation and anti-Ly6G-mediated neutrophil depletion
- Creator: Donovan, Chantal , Kim, Richard Y , Khan, Haroon , Pickles, Sophie , Sahu, Priyanka , Chimankar, Vrushali , Tu, Xiaofan , Ali, Md Khadem , Mayall, Jemma R. , Nguyen, Duc H. , Budden, Kurtis F. , Kumar, Vinod , Galvao, Izabela , Wark, Peter A. B. , Horvat, Jay C. , Hansbro, Philip M. , Ab Wark, P , Oliver, BG , Horvat, JC , Hansbro, PM , Jarnicki, Andrew G. , Brown, Alexandra C. , Jones-Freeman, Bernadette , Gomez, Henry M. , Wadhwa, Ridhima , Hortle, Elinor , Jayaraman, Ranjith
- Resource Type: journal article
- Date: 2022
Airway and parenchymal transcriptomics in a novel model of asthma and COPD overlap
- Creator: Tu, Xiaofan , Kim, Richard Y. , Loering, Svenja , Nguyen, Duc H. , Nair, Prema Mono , Haw, Tatt Jhong , Alemao, Charlotte A. , Faiz, Alen , Tay, Hock L. , Wark, Peter A. B. , Knight, Darryl A. , Foster, Paul S. , Brown, Alexandra C. , Bosco, Anthony , Horvat, Jay C. , Hansbro, Philip M. , Donovan, Chantal , de Jong, Emma , Jones-Freeman, Bernadette , Ali, Md Khadem , Gomez, Henry M. , Budden, Kurtis F. , Starkey, Malcolm R. , Cameron, Guy J. M.
- Resource Type: journal article
- Date: 2022
Generation of cardio-protective antibodies after pneumococcal polysaccharide vaccine: Early results from a randomised controlled trial
- Creator: Ren, Shu , Hansbro, Philip M. , Srikusalanukul, Wichat , Horvat, Jay C. , Hunter, Tegan , Brown, Alexandra C. , Peel, Roseanne , Faulkner, Jack , Evans, Tiffany-Jane , Li, Shu Chuen , Newby, David , Hure, Alexis , Abhayaratna, Walter P. , Tsimikas, Sotirios , Gonen, Ayelet , Witztum, Joseph L. , Attia, John
- Resource Type: journal article
- Date: 2022
Increased SARS-CoV-2 Infection, Protease, and Inflammatory Responses in Chronic Obstructive Pulmonary Disease Primary Bronchial Epithelial Cells Defined with Single-Cell RNA Sequencing
- Creator: Johansen, Matt D. , Mahbub, Rashad M. , Gallego-Ortega, David , Britton, Warwick J. , Saunders, Bernadette M. , Wark, Peter A. , Faiz, Alen , Hansbro, Philip M. , Idrees, Sobia , Nguyen, Duc H. , Miemczyk, Stefan , Pathinayake, Prabuddeha , Nichol, Kristy , Hansbro, Nicole G. , Gearing, Linden J. , Hertzog, Paul J.
- Resource Type: journal article
- Date: 2022
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages
- Creator: Runtsch, Marah C. , Angiari, Stefano , Mendez, Rui Santalla , Zotta, Alessia , Peace, Christian G. , Walsh, Aoife , Chirillo, Roberta , Hams, Emily , Fallon, Padraic G. , Jayamaran, Ranjith , Dua, Kamal , Brown, Alexandra C. , Hooftman, Alexander , Kim, Richard Y. , Horvat, Jay C. , Hansbro, Philip M. , Wang, C , O'Neill, LAJ , Wadhwa, Ridhima , Zhang, Yanling , Zheng, Yunan , Spina, Joseph S. , Ruzek, Melanie C. , Argiriadi, Maria A. , McGettrick, Anne F.
- Resource Type: journal article
- Date: 2022
Relationship between type 2 cytokine and inflammasome responses in obesity-associated asthma
- Creator: Pinkerton, James W. , Kim, Richard Y. , Baines, Katherine J. , Starkey, Malcolm R. , Kermani, Nazanin Z. , Guo, Yi-Ke , Robertson, Avril A. B. , O'Neill, Luke A. J. , Adcock, Ian M. , Cooper, Matthew A. , Gibson, Peter G. , Wood, Lisa G. , Brown, Alexandra C. , Hansbro, Philip M. , Horvat, Jay C. , Rae, Brittany E. , Donovan, Chantal , Mayall, Jemma R. , Carroll, Olivia R. , Ali, Md. Khadem , Scott, Hayley A. , Berthon, Bronwyn S.
- Resource Type: journal article
- Date: 2022
Therapeutic Targeting of the Respiratory Microbiome
- Creator: Chotirmall, Sanjay H. , Bogaert, Debby , Segal, Leopoldo N. , Dickson, Robert P. , Chalmers, James D. , Cox, Michael J. , Hansbro, Philip M. , Huang, Yvonne J. , Molyneaux, Philip L. , O'Dwyer, David N. , Pragman, Alexa A. , Rogers, Geraint B.
- Resource Type: journal article
- Date: 2022
Type 2 immune polarization is associated with cardiopulmonary disease in preterm infants
- Creator: Lao, Jason C. , Bui, Christine B. , Skuza, Elizabeth M. , Sun, Yu B. Y. , Beker, Friederike , Collins, Clare L. , Kamlin, Omar F. , König, Kai , Malhotra, Atul , Tan, Kenneth , Theda, Christiane , Young, Morag J. , Pang, Merrin A. , McLean, Catriona A. , Hansbro, Philip M. , ., , Cho, Steven X. , Rudloff, Ina , Elgass, Kirstin , Schröder, Jan , Maksimenko, Anton , Mangan, Niamh E. , Starkey, Malcolm R.
- Resource Type: journal article
- Date: 2022
A monoclonal antibody to Siglec-8 suppresses non-allergic airway inflammation and inhibits IgE-independent mast cell activation
- Creator: Schanin, Julia , Gebremeskel, Simon , Evensen, Erik , Brock, Emily C. , Xu, Alan , Wong, Alan , Leung, John , Bebbington, Christopher , Tomasevic, Nenad , Youngblood, Bradford A. , Korver, Wouter , Falahati, Rustom , Butuci, Melina , Haw, Tatt Jhong , Nair, Prema M. , Liu, Gang , Hansbro, Nicole G. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2021
ACE2 expression is elevated in airway epithelial cells from older and male healthy individuals but reduced in asthma
- Creator: Wark, Peter A. B. , Pathinayake, Prabuddha S. , Eapen, Mathew S. , Oldmeadow, Christopher , Bartlett, Nathan , Reid, Andrew , Veerati, Punnam , Hsu, Alan C.-Y. , Looi, Kevin , Iosifidis, Thomas , Stick, Stephen M. , Hansbro, Philip M. , Kaiko, Gerard , Kicic, Anthony , Nichol, Kristy , Ali, Ayesha , Chen, Ling , Sutanto, Erika N. , Garratt, Luke W. , Sohal, Sukhwinder S. , Lu, Wenying
- Resource Type: journal article
- Date: 2021
Anti-inflammatory and anticancer activities of Naringenin-loaded liquid crystalline nanoparticles in vitro
- Creator: Wadhwa, Ridhima , Paudel, Keshav Raj , Dureja, Harish , Hsu, Alan , Mehta, Meenu , Anand, Krishnan , Devkota, Hari Prasad , Chellian, Jestin , Chellappan, Dinesh Kumar , Hansbro, Philip M. , Dua, Kamal , Chin, Li Hian , Hon, Chian Ming , Madheswaran, Thiagarajan , Gupta, Gaurav , Panneerselvam, Jithendra , Lakshmi, Thangavelu , Singh, Sachin Kumar , Gulati, Monica
- Resource Type: journal article
- Date: 2021
Asthma-COPD overlap: current understanding and the utility of experimental models
- Creator: Tu, Xiaofan , Donovan, Chantal , Kim, Richard Y. , Wark, Peter A. B. , Horyat, Jay C. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2021
Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma
- Creator: Jacquelot, Nicolas , Seillet, Cyril , Souza-Fonseca-Guimaraes, Fernando , de Graaf, Carolyn A. , Thia, Kevin , Macdonald, Sean , Camilleri, Mary , Luong, Kylie , Zhang, Shengbo , Chopin, Michael , Molden-Hauer, T. , Nutt, S. L. , Wang, Minyu , Umansky, V. , Ciric, B. , Groom, J.R. , Foster, Paul S. , Hansbro, Philip M. , McKenzie, A. N. J. , Gray, D .H .D. , Behren, A. , Cebon, J. , Vivier, E. , Pizzolla, Angela , Wicks, I. P. , Trapani, J. A. , Munitz, A. , Davis, M. J. , Shi, W. , Neeson, P. J. , Belz, G. T. , Liao, Yang , Hediyeh-zadeh, Soroor , Grisaru-Tal, Sharon , Louis, Cynthia , Huang, Qiutong , Schreuder, Jaring
- Resource Type: journal article
- Date: 2021
Cord blood group 2 innate lymphoid cells are associated with lung function at 6 weeks of age
- Creator: Martins Costa Gomes, Gabriela , de Gouveia Belinelo, Patricia , Starkey, Malcolm R. , Murphy, Vanessa E. , Hansbro, Philip M. , Sly, Peter D. , Robinson, Paul D. , Karmaus, Wilfried , Gibson, Peter G. , Mattes, Joerg , Collison, Adam M.
- Resource Type: journal article
- Date: 2021
Differences in pulmonary group 2 innate lymphoid cells are dependent on mouse age, sex and strain
- Creator: Loering, Svenja , Cameron, Guy J. M. , Bhatt, Nirmal P. , Belz, Gabrielle T. , Foster, Paul S. , Hansbro, Philip M. , Starkey, Malcolm R.
- Resource Type: journal article
- Date: 2021