A monoclonal antibody to Siglec-8 suppresses non-allergic airway inflammation and inhibits IgE-independent mast cell activation
- Creator: Schanin, Julia , Gebremeskel, Simon , Evensen, Erik , Brock, Emily C. , Xu, Alan , Wong, Alan , Leung, John , Bebbington, Christopher , Tomasevic, Nenad , Youngblood, Bradford A. , Korver, Wouter , Falahati, Rustom , Butuci, Melina , Haw, Tatt Jhong , Nair, Prema M. , Liu, Gang , Hansbro, Nicole G. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2021
A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis
- Creator: Beckett, Emma L. , Stevens, Richard L. , Oliver, Brian G. , van Rooijen, Nico , Inman, Mark D. , Adachi, Roberto , Soberman, Roy J. , Hamadi, Sahar , Wark, Peter A. , Foster, Paul S. , Hansbro, Philip M. , Jarnicki, Andrew G. , Kim, Richard Y. , Hanish, Irwan , Hansbro, Nicole G. , Deane, Andrew , Keely, Simon , Horvat, Jay C. , Yang, Ming
- Resource Type: journal article
- Date: 2013
Adverse roles of mast cell chymase-1 in chronic obstructive pulmonary disease
- Creator: Liu, Gang , Jarnicki, Andrew G. , Paudel, Keshav R. , Lu, Wenying , Wadhwa, Ridhima , Philp, Ashleigh M. , Van Eeckhoutte, Hannelore , Marshall, Jacqueline E. , Malyla, Vamshikrishna , Katsifis, Angelica , Fricker, Michael , Hansbro, Nicole G. , Dua, Kamal , Kermani, Nazanin Z. , Eapen, Mathew S. , Tiotiu, Angelica , Chung, K. Fan , Caramori, Gaetano , Bracke, Ken , Adcock, Ian M. , Wark, Peter A. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2022
Adverse roles of mast cell chymase-1 in COPD
- Creator: Liu, Gang , Jarnicki, Andrew G. , Fricker, Michael , Hansbro, Nicole G. , Dua, Kamal , Kermani, Nazanin Z. , Eapen, Mathew S. , Tiotiu, Angelica , Chung, K. Fan , Caramori, Gaetano , Bracke, Ken , Adcock, Ian M. , Paudel, Keshav R. , Sohal, Sukhwinder S. , Wark, Peter A. , Oliver, Brian G. , Hansbro, Philip M. , Lu, Wenying , Wadhwa, Ridhima , Philp, Ashleigh M. , Van Eeckhoutte, Hannelore , Marshall, Jacqueline E. , Malyla, Vamshikrishna , Katsifis, Angelica
- Resource Type: journal article
- Date: 2022
Airway remodelling and inflammation in asthma are dependent on the extracellular matrix protein fibulin-1c
- Creator: Liu, Gang , Cooley, Marion A. , Tay, Hock , Foster, Paul S. , Wark, Peter A. , Horvat, Jay C. , Bourke, Jane E. , Grainge, Chris L. , Argraves, W. Scott , Oliver, Brian G. , Knight, Darryl A. , Burgess, Janette K. , Nair, Prema M. , Hansbro, Philip M. , Donovan, Chantal , Hsu, Alan C. , Jarnicki, Andrew G. , Haw, Tatt Jhong , Hansbro, Nicole G. , Ge, Qi , Brown, Alexandra C.
- Resource Type: journal article
- Date: 2017
Antiproliferative effects of boswellic acids-loaded chitosan nanoparticles on human lung cancer cell line A549
- Creator: Solanki, Neeta , Mehta, Meenu , Hansbro, Philip M. , Dua, Kamal , Dureja, Harish , Chellappan, Dinesh Kumar , Gupta, Gaurav , Hansbro, Nicole G. , Tambuwala, Murtaza M. , Aljabali, Alaa Aa , Paudel, Keshav Raj , Liu, Gang , Satija, Saurabh
- Resource Type: journal article
- Date: 2020
Antiviral Responses of Tissue-resident CD49a+ Lung Natural Killer Cells Are Dysregulated in Chronic Obstructive Pulmonary Disease
- Creator: Cooper, Grace E. , Mayall, Jemma , Khakoo, Salim I. , Wilkinson, Tom M. A. , Hansbro, Philip M. , Staples, Karl J. , Donovan, Chantal , Haw, Tatt J. , Budden, Kurtis F. , Hansbro, Nicole G. , Blomme, Evy E. , Maes, Tania , Kong, Chia Wei , Horvat, Jay C.
- Resource Type: journal article
- Date: 2023
Celastrol-loaded liquid crystalline nanoparticles as an anti-inflammatory intervention for the treatment of asthma
- Creator: Chan, Yinghan , Ng, Sin Wi , Chellappan, Dinesh Kumar , Madheswaran, Thiagarajan , Zeeshan, Farrukh , Kumar, Pradeep , Pillay, Viness , Gupta, Gaurav , Wadhwa, Ridhima , Mehta, Meenu , Wark, Peter , Hsu, Alan , Hansbro, Nicole G. , Hansbro, Philip Michael , Dua, Kamal , Panneerselvam, Jithendra
- Resource Type: journal article
- Date: 2020
Characterization and inhibition of inflammasome responses in severe and non-severe asthma
- Creator: Horvat, Jay C. , Kim, Richard Y. , Weaver, Natasha , Augood, Christopher , Brown, Alexandra C. , Donovan, Chantal , Dupre, Pierrick , Gunawardhana, Lakshitha , Mayall, Jemma R. , Hansbro, Nicole G. , Robertson, Avril A. B. , O'Neill, Luke A. J. , Cooper, Matthew A. , Holliday, Elizabeth G. , Hansbro, Philip M. , Gibson, Peter G.
- Resource Type: journal article
- Date: 2023
Curcumin-loaded niosomes downregulate mRNA expression of pro-inflammatory markers involved in asthma: an in vitro study
- Creator: Wong, Jin-Ying , Ng, Zhao Yin , Hsu, Alan , Hansbro, Nicole G. , Wark, Peter , Bebawy, Mary , Hansbro, Philip Michael , Dua, Kamal , Chellappan, Dinesh Kumar , Mehta, Meenu , Shukla, Shakti D. , Panneerselvam, Jithendra , Madheswaran, Thiagarajan , Gupta, Gaurav , Negi, Poonam , Kumar, Pradeep , Pillay, Viness
- Resource Type: journal article
- Date: 2020
Development of asthmatic inflammation in mice following early-life exposure to ambient environmental particulates and chronic allergen challenge
- Creator: Herbert, Cristan , Siegle, Jessica S. , Shadie, Alexander M. , Nikolaysen, Stina , Garthwaite, Linda , Hansbro, Nicole G. , Foster, Paul S. , Kumar, Rakesh K.
- Resource Type: journal article
- Date: 2013
Elastin is a key factor of tumor development in colorectal cancer
- Creator: Li, Jinzhi , Xu, Xiaoyue , Jiang, Yanyan , Hansbro, Nicole G. , Hansbro, Philip M. , Xu, Jincheng , Liu, Gang
- Resource Type: journal article
- Date: 2020
Emerging concepts and directed therapeutics for the management of asthma: regulating the regulators
- Creator: Shastri, Madhur , Chong, Wai Chin , Hansbro, Philip M. , Dua, Kamal , Peterson, Gregory M. , Patel, Rahul P. , Mahmood, Malik Q. , Tambuwala, Murtaza , Chellappan, Dinesh K. , Hansbro, Nicole G. , Shukla, Shakti D.
- Resource Type: journal article
- Date: 2020
Epigenetic changes associated with disease progression in a mouse model of childhood allergic asthma
- Creator: Collison, Adam , Siegle, Jessica S. , Hansbro, Nicole G. , Kwok, Chau-To , Herbert, Cristan , Mattes, Joerg , Hitchins, Megan , Foster, Paul S. , Kumar, Rakesh K.
- Resource Type: journal article
- Date: 2013
Fibulin-1 Is increased in asthma: a novel mediator of airway remodeling?
- Creator: Lau, Justine Y. , Oliver, Brian G. , Black, Judith L. , Burgess, Janette K. , Baraket, Melissa , Beckett, Emma L. , Hansbro, Nicole G. , Moir, Lyn M. , Wilton, Steve D. , Williams, Carolyn , Foster, Paul S. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2010
Fibulin-1c regulates transforming growth factor-beta activation in pulmonary tissue fibrosis
- Creator: Liu, Gang , Cooley, Marion A. , Jones, Berrnadette , Hansbro, Nicole G. , Wark, Peter A. , Horvat, Jay C. , Argraves, W. Scott , Oliver, Brian G. , Knight, Darryl A. , Burgess, Janette K. , Hansbro, Philip M. , Jarnicki, Andrew G. , Borghuis, Theo , Nair, Prema M. , Tjin, Gavin , Hsu, Alan C. , Haw, Tatt Jhong , Fricker, Michael , Harrison, Celeste L.
- Resource Type: journal article
- Date: 2019
Granulocyte-macrophage colony-stimulating factor is required for bronchial eosinophilia in a murine model of allergic airway inflammation
- Creator: Su, Yung-Chang , Rolph, Michael S. , Hansbro, Nicole G. , Mackay, Charles R. , Sewell, William A.
- Resource Type: journal article
- Date: 2008
Human beta-defensin-2 suppresses key features of asthma in murine models of allergic airways disease
- Creator: Pinkerton, James W. , Kim, Richard Y. , Nordkild, Peter , Horvat, Jay C. , Jensen, Benjanim A. H. , Wehkamp, Jan , Hansbro, Philip M. , Koeninger, Louis , Armbruster, Nicole S. , Hansbro, Nicole G. , Brown, Alexandra C. , Jayaraman, Ranjith , Shen, Sijie , Malek, Nisar , Cooper, Matthew A.
- Resource Type: journal article
- Date: 2020
IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis
- Creator: Starkey, Malcolm R. , Plank, Maximilian W. , Donovan, Chantal , Hansbro, Nicole G. , Nguyen, Duc H. , Nair, Prema Mono , Kim, Richard Y. , Horvat, Jay C. , Kaiko, Gerard E. , Durum, Scott K. , Wark, Peter A. , Sin, Don D. , Casolari, Paolo , Caramori, Gaetano , Adcock, Ian M. , Foster, Paul S. , Hansbro, Philip M. , Papi, Alberto , Pavlidis, Stelios , Guo, Yike , Cameron, Guy J. M. , Haw, Tatt Jhong , Tam, Anthony , Obiedat, Maen
- Resource Type: journal article
- Date: 2019
Increased SARS-CoV-2 Infection, Protease, and Inflammatory Responses in Chronic Obstructive Pulmonary Disease Primary Bronchial Epithelial Cells Defined with Single-Cell RNA Sequencing
- Creator: Johansen, Matt D. , Mahbub, Rashad M. , Gallego-Ortega, David , Britton, Warwick J. , Saunders, Bernadette M. , Wark, Peter A. , Faiz, Alen , Hansbro, Philip M. , Idrees, Sobia , Nguyen, Duc H. , Miemczyk, Stefan , Pathinayake, Prabuddeha , Nichol, Kristy , Hansbro, Nicole G. , Gearing, Linden J. , Hertzog, Paul J.
- Resource Type: journal article
- Date: 2022