A primer on the use of machine learning to distil knowledge from data in biological psychiatry
- Creator: Quinn, Thomas P. , Hess, Jonathan L. , Breen, Michael S. , Barnett, Eric J. , Zhang-James, Yanli , Ahsen, Mehmet Eren , Cao, Han , Chen, Junfang , Hou, Jiahui , Salekin, Asif , Lin, Ping-I , Nicodemus, Kristin K. , Marshe, Victoria S. , Meyer-Lindenberg, Andreas , Bichindaritz, I , Faraone, SV , Cairns, Murray J. , Pandey, G , Müller, DJ , Glatt, SJ , Barnett, Michelle M. , Hauschild, Anne-Christin , Maciukiewicz, Malgorzata , Elsheikh, Samar S. M. , Men, Xiaoyu , Schwarz, Emanuel , Trakadis, Yannis J.
- Resource Type: journal article
- Date: 2024
Alteration of DNA Methylation and Epigenetic Scores Associated with Features of Schizophrenia and Common Variant Genetic Risk
- Creator: Kiltschewskij, Dylan J. , Reay, William R. , Cairns, Murray J. , Geaghan, Michael P. , Atkins, Joshua R. , Xavier, Alexandre , Zhang, Xiajie , Watkeys, Oliver J. , Carr, Vaughan J. , Scott, Rodney J. , Green, Melissa J.
- Resource Type: journal article
- Date: 2024
Beyond the global brain differences: intra-individual bariability differences in 1q21.1 distal and 15q11.2 BP1-BP2 deletion carriers
- Creator: Boen, Rune , Kaufmann, Tobias , van der Meer, Dennis , Frei, Oleksandr , Agartz, Ingrid , Ames, David , Andersson, Micael , Armstrong, Nicola J. , Artiges, Eric , Atkins, Joshua R. , Bauer, Jochen , Benedetti, Francesco , Boomsma, Dorret I. , Brodaty, Henry , Brosch, Katharina , Buckner, Randy L. , Cairns, Murray J. , Calhoun, Vince , Caspers, Svenja , Cichon, Sven , Trollor, JN , van 't Ent, D , van den Bree, MBM , van Haren, NEM , Vazquez-Bourgon, J , Volzke, H , Wen, W , Wittfeld, K , Ching, CRK , Westlye, LT , Thompson, PM , Bearden, CE , Selmer, KK , Alnæs, D , Andreassen, OA , Sonderby, IE , Grøntvedt, Gøril Rolfseng , Corvin, Aiden P. , Crespo-Facorro, Benedicto , Dannlowski, U , David, FS , de Geus, EJC , de Zubicaray, GI , Desrivières, S , Doherty, JL , Donohoe, G , Ehrlich, S , Eising, E , Espeseth, T , Fisher, SE , Forstner, AJ , Uyà, LF , Frouin, V , Fukunaga, M , Ge, T , Glahn, DC , Goltermann, J , Grabe, HJ , Green, MJ , Groenewold, NA , Grotegerd, D , Hahn, T , Hashimoto, R , Hehir-Kwa, JY , Henskens, Frans A. , Holmes, AJ , Haberg, AK , Haavik, J , Jacquemont, S , Jansen, A , Jockwitz, C , Jonsson, EG , Kikuchi, M , Kircher, T , Kumar, K , Le Hellard, S , Leu, C , Linden, DE , Liu, J , Loughnan, R , Mather, KA , McMahon, KL , McRae, AF , Medland, SE , Meinert, S , Moreau, CA , Morris, DW , Mowry, BJ , Muhleisen, TW , Nenadić, I , Nöthen, MM , Nyberg, L , Owen, MJ , Paolini, M , Paus, T , Pausova, Z , Persson, K , Quidé, Y , Marques, TR , Sachdev, PS , Sando, SB , Schall, U , Scott, Rodney J. , Selbæk, G , Shumskaya, E , Silva, AI , Sisodiya, SM , Stein, F , Stein, DJ , Straube, B , Streit, F , Strike, LT , Teumer, A , Teutenberg, L , Thalamuthu, A , Tooney, Paul A. , Tordesillas-Gutierrez, D
- Resource Type: journal article
- Date: 2024
Cortical similarities in psychiatric and mood disorders identified in federated VBM analysis via COINSTAC
- Creator: Rootes-Murdy, Kelly , Panta, Sandeep , Green, Melissa J. , Henskens, Frans , Kiltschewskij, Dylan , Michie, Patricia T. , Mowry, Bryan , Pantelis, Christos , Rasser, Paul E. , Reay, William R. , Schall, Ulrich , Scott, Rodney J. , Kelly, Ross , Watkeys, Oliver J. , Roberts, G , Mitchell, P , Fullerton, JM , Overs, BJ , Kikuchi, M , Hashimoto, R , Matsumoto, J , Fukunaga, M , Sachdev, PS , Romero, Javier , Brodaty, H , Wen, W , Jiang, J , Fani, N , Ely, TD , Lorio, A , Stevens, JS , Ressler, K , Jovanovic, T , van Rooij, SJH , Quidé, Yann , Federmann, LM , Jockwitz, C , Teumer, A , Forstner, AJ , Caspers, S , Cichon, S , Plis, SM , Sarwate, AD , Calhoun, VD , Cairns, Murray J. , Loughland, Carmel , Carr, Vaughan J. , Catts, Stanley V. , Jablensky, Assen
- Resource Type: journal article
- Date: 2024
Linking Polygenic Risk of Schizophrenia to Variation in Magnetic Resonance Imaging Brain Measures: A Comprehensive Systematic Review
- Creator: Jameei, Hadis , Rakesh, Divyangana , Zalesky, Andrew , Cairns, Murray J. , Reay, William R. , Wray, Naomi R. , Di Biase, Maria A.
- Resource Type: journal article
- Date: 2024
PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma
- Creator: Duchatel, Ryan J. , Jackson, Evangeline R. , Kearney, Padraic S. , Jamaluddin, M. Fairuz B. , Douglas, Alicia M. , Beitaki, Tyrone , McEwen, Holly P. , Persson, Mika L. , Hocke, Emily A. , Jain, Vaibhav , Aksu, Michael , Manning, Elizabeth E. , Parackal, Sarah G. , Murray, Heather C. , Verrills, Nicole M. , Hua, Susan , Cairns, Murray J. , Alvaro, Frank , Dayas, Christopher V. , Dun, Matthew D. , Hua, S , de Bock, CE , Colino-Sanguino, Y , Kiltschewskij, Dylan , Valdes-Mora, F , Tsoli, M , Ziegler, DS , Cairns, MJ , Raabe, EH , Vitanza, NA , Hulleman, E , Phoenix, TN , Koschmann, C , Alvaro, F , Findlay, Izac J. , Dayas, CV , Tinkle, CL , Wheeler, H , Whittle, JR , Eisenstat, DD , Firestein, R , Mueller, S , Valvi, S , Hansford, JR , Ashley, DM , Mannan, Abdul , Gregory, SG , Kilburn, LB , Nazarian, J , Cain, JE , Dun, MD , Staudt, Dilana E. , Thomas, Bryce C. , Germon, Zacary P. , Laternser, Sandra
- Resource Type: journal article
- Date: 2024
Using Genetics to Inform Interventions Related to Sodium and Potassium in Hypertension
- Creator: Reay, William R. , Clarke, Erin , Collins, Clare E. , Cairns, Murray J. , Eslick, Shaun , Riveros, Carlos , Holliday, Elizabeth G. , McEvoy, Mark A. , Peel, Roseanne , Hancock, Stephen , Scott, Rodney J. , Attia, John R.
- Resource Type: journal article
- Date: 2024
A polygenic resilience score moderates the genetic risk for schizophrenia: Replication in 18,090 cases and 28,114 controls from the Psychiatric Genomics Consortium
- Creator: Hess, Jonathan L. , Mattheisen, Manuel , Henskens, Frans A. , Kelly, Brian J. , Loughland, Carmel M. , Michie, Patricia T. , Schall, Ulrich , Scott, Rodney J. , Tooney, Paul A. , Schizophrenia Working Group of the Psychiatric Genomics Consortium, , Greenwood, Tiffany A. , Tsuang, Ming T. , Edenberg, Howard J. , Holmans, Peter , Faraone, Stephen V. , Glatt, Stephen J. , Cairns, Murray J.
- Resource Type: journal article
- Date: 2023
Exploring opportunities for drug repurposing and precision medicine in cannabis use disorder using genetics
- Creator: Greco, Laura A. , Reay, William R. , Dayas, Christopher V. , Cairns, Murray J.
- Resource Type: journal article
- Date: 2023
Extension of mRNA poly(A) tails and 3 ' UTRs during neuronal differentiation exhibits variable association with post-transcriptional dynamics
- Creator: Kiltschewskij, Dylan J. , Harrison, Paul F. , Fitzsimmons, Chantel , Beilharz, Traude H. , Cairns, Murray J.
- Resource Type: journal article
- Date: 2023
Heritable defects in telomere and mitotic function selectively predispose to sarcomas
- Creator: Ballinger, Mandy L. , Pattnaik, Swetansu , van der Graaf, Winette T. A. , Fennelly, V , Wicht, A , Zielony, B , Galligan, E , Glavich, G , Stoeckert, J , Williams, L , Djandjgava, L , Buettner, I , Osinki, C , Puri, Ajay , Stephens, S , Rogasik, M , Bouclier, L , Girodet, M , Charreton, A , Fayet, Y , Crasto, S , Sandupatla, B , Yoon, Y , Je, N , Duffaud, Florence , Thompson, L , Fowler, T , Johnson, B , Petrikova, G , Hambridge, T , Hutchins, A , Bottero, D , Scanlon, D , Stokes-Denson, J , Génin, E , Le Cesne, Axel , Campion, D , Dartigues, J-F , Deleuze, J-F , Lambert, J-C , Redon, R , Ludwig, T , Grenier-Boley, B , Letort, S , Lindenbaum, P , Meyer, V , Seddon, Beatrice , Quenez, O , Dina, C , Bellenguez, C , Le Clézio, CC , Giemza, J , Chatel, S , Férec, C , Le Marec, H , Letenneur, L , Nicolas, G , Chandrasekar, Coonoor , Rouault, K , Schiffman, Joshua D. , Brohl, Andrew S. , James, Paul A. , Kurtz, Jean-Emmanuel , Mundra, Piyushkumar A. , Penel, Nicolas , Myklebost, Ola , Meza-Zepeda, LA , Pickett, H , Kansara, M , Waddell, N , Kondrashova, O , Pearson, JV , Barbour, AP , Li, S , Zaheed, Milita , Nguyen, TL , Fatkin, D , Graham, RM , Giannoulatou, E , Green, MJ , Kaplan, W , Ravishankar, S , Copty, J , Powell, JE , Cuppen, E , Rath, Emma , van Eijk, K , Veldink, J , Ahn, J-H , Kim, JE , Randall, RL , Tucker, K , Judson, I , Sarin, R , Genin, E , Priestley, Peter , French Exome Project Consortium, , Haber, M , Marshall, G , Cairns, Murray J. , Blay, J-Y , International Sarcoma Kindred Study, , Thomas, DM , Tattersall, M , Neuhaus, S , Baber, Jonathan , Lewis, C , Carey-Smith, R , Wood, D , Porceddu, S , Dickinson, I , Thorne, H , James, P , Ray-Coquard, I , Ray-Coquard, Isabelle , Cassier, P , Le Cesne, A , Duffaud, F , Penel, N , Isambert, N , Kurtz, J-E , Puri, A , Isambert, Nicholas , Ward, I , van der Graaf, W , Seddon, B , Chandrasekar, C , Rickar, R , Hennig, I , Schiffman, J , Silvestri, A , Causeret, Sylvain , Zaratzian, A , Tayao, M , Walwyn, K , Niedermayr, E , Mang, D , Clark, R , Thorpe, T , MacDonald, J , Riddell, K , Mar, J
- Resource Type: journal article
- Date: 2023
miRNA cargo in circulating vesicles from neurons is altered in individuals with schizophrenia and associated with severe disease
- Creator: Barnett, Michelle M. , Reay, William R. , Geaghan, Michael P. , Kiltschewskij, Dylan J. , Green, Melissa J. , Weidenhofer, Judith , Glatt, Stephen J. , Cairns, Murray J.
- Resource Type: journal article
- Date: 2023
Multiomic prioritisation of risk genes for anorexia nervosa
- Creator: Adams, Danielle M. , Reay, William R. , Cairns, Murray J.
- Resource Type: journal article
- Date: 2023
Schizophrenia risk conferred by rare protein-truncating variants is conserved across diverse human populations
- Creator: Liu, Dongjing , Meyer, Dara , Dobbyn, Amanda , Schall, Ulrich , Scott, Rodney J. , Tooney, Paul A. , Lebovitch, Dannielle , Moya, Emily , Nguyen, Tan-Hoang , Wilkins, Lillian , Hassan, Arsalan , Aghanwa, Henry S. , Ansari, Moin , Asif, Aftab , Aslam, Rubina , Fennessy, Brian , Ayuso, JL , Bigdeli, T , Bignotti, S , Bobes, J , Bradley, B , Buckley, P , Cairns, Murray J. , Catts, SV , Chaudhry, AR , Cohen, D , Feng, Claudia , Collins, BL , Consoli, A , Costas, J , Crespo-Facorro, B , Daskalakis, NP , Davidson, M , Davis, KL , Dickerson, F , Dogar, IA , Drapeau, E , Cheng, Esther , Fañanás, L , Fanous, A , Fatima, W , Fatjo, M , Filippich, C , Friedman, J , Fullard, JF , Georgakopoulos, P , Giannitelli, M , Giegling, I , Johnson, Jessica S. , Green, MJ , Guillin, O , Gutierrez, B , Handoko, HY , Hansen, SK , Haroon, M , Haroutunian, V , Henskens, Frans A. , Hussain, F , Jablensky, AV , Park, You Jeong , Junejo, J , Kelly, Brian J. , Khan, SUDA , Khan, MNS , Khan, A , Khawaja, HR , Khizar, B , Kleopoulos, SP , Knowles, J , Konte, B , Rieder, Marysia-Kolbe , Kusumawardhani, AAAA , Leghari, N , Liu, X , Lori, A , Loughland, Carmel M. , Mahmood, K , Mahmood, S , Malaspina, D , Malik, D , McNaughton, A , Ascolillo, Steven , Michie, Patricia T. , Michopolous, V , Molina, E , Molto, MD , Munir, A , Muntané, G , Naeem, F , Nancarrow, DJ , Nasar, A , Nasr, T , de Pins, Agathe , Ohaeri, JU , Ott, J , Pantelis, C , Periyasamy, S , Pinto, AG , Powers, A , Ramos, B , Rana, NH , Rapaport, M , Reichenberg, A
- Resource Type: journal article
- Date: 2023
Cell type-specific manifestations of cortical thickness heterogeneity in schizophrenia
- Creator: Di Biase, Maria A. , Geaghan, Michael P. , Bouix, Sylvain , Knyazhanskaya, Evdokiya E. , Lyall, Amanda E. , Pasternak, Ofer , Kubicki, Marek , Rathi, Yogesh , Visco, Andrew , Gaunnac, Megan , Lv, Jinglei , Mesholam-Gately, Raquelle I. , Reay, William R. , Cairns, Murray J. , Holt, DJ , Keshavan, MS , Pantelis, C , Öngür, D , Breier, A , Cairns, MJ , Shenton, ME , Zalesky, A , Seidlitz, Jakob , Weickert, Cynthia Shannon , Pébay, Alice , Green, Melissa J. , Quidé, Yann , Atkins, Joshua R. , Coleman, Michael J.
- Resource Type: journal article
- Date: 2022
Data analysis guidelines for single-cell RNA-seq in biomedical studies and clinical applications
- Creator: Su, Min , Pan, Tao , He, Xiao , Jiang, Chun-Jie , Fan, Shi-Cai , Li, Xia , Cairns, Murray J. , Wang, Xi , Li, Yong-Sheng , Chen, Qiu-Zhen , Zhou, Wei-Wei , Gong, Yi , Xu, Gang , Yan, Huan-Yu , Li, Si , Shi, Qiao-Zhen , Zhang, Ya
- Resource Type: journal article
- Date: 2022
Developmental vitamin D-deficiency increases the expression of microRNAs involved in dopamine neuron development
- Creator: Pertile, Renata Aparecida Nedel , Kiltschewskij, Dylan , Geaghan, Michael , Barnett, Michelle , Cui, Xiaoying , Cairns, Murray J. , Eyles, Darryl
- Resource Type: journal article
- Date: 2022
Evidence of genetic overlap and causal relationships between blood-based biochemical traits and human cortical anatomy
- Creator: Kiltschewskij, Dylan J. , Reay, William R. , Cairns, Murray J.
- Resource Type: journal article
- Date: 2022
Genetic estimates of correlation and causality between blood-based biomarkers and psychiatric disorders
- Creator: Reay, William R. , Kiltschewskij, Dylan J. , Geaghan, Michael P. , Atkins, Joshua R. , Carr, Vaughan J. , Green, Melissa J. , Cairns, Murray J.
- Resource Type: journal article
- Date: 2022
Genetics-informed precision treatment formulation in schizophrenia and bipolar disorder
- Creator: Reay, William R. , Geaghan, Michael P. , Atkins, Joshua R. , Carr, Vaughan J. , Green, Melissa J. , Cairns, Murray J.
- Resource Type: journal article
- Date: 2022