Next-generation of BBQ analogues that selectively target breast cancer
- Creator: Baker, Jennifer R. , Gilbert, Jayne , O'Brien, Nicholas S. , Russell, Cecilia C. , Mccluskey, Adam , Sakoff, Jennette A.
- Resource Type: journal article
- Date: 2024
Novel piperazine-1,2,3-triazole leads for the potential treatment of pancreatic cancer
- Creator: Sun, Jufeng , Baker, Jennifer R. , Russell, Cecilia C. , Pham, Hong N. T. , Goldsmith, Chloe D. , Cossar, Peter J. , Sakoff, Jennette A. , Scarlett, Christopher J. , McCluskey, Adam
- Resource Type: journal article
- Date: 2023
Systematic literature review reveals suboptimal use of chemical probes in cell-based biomedical research
- Creator: Sterling, Jayden , Baker, Jennifer R. , McCluskey, Adam , Munoz, Lenka
- Resource Type: journal article
- Date: 2023
Wiskostatin and other carbazole scaffolds as off target inhibitors of dynamin I GTPase activity and endocytosis
- Creator: Cossar, Peter J. , Cardoso, David , McCluskey, Adam , Mathwin, Daniel , Russell, Cecilia C. , Chiew, Beatrice , Hamilton, Michael P. , Baker, Jennifer R. , Young, Kelly A. , Chau, Ngoc , Robinson, Phillip J.
- Resource Type: journal article
- Date: 2023
3,5-Bis(trifluoromethyl)phenylsulfonamides, a novel pancreatic cancer active lead. Investigation of the terminal aromatic moiety
- Creator: Sun, Jufeng , Ambrus, Joey I. , Baker, Jennifer R. , Russell, Cecilia C. , Cossar, Peter J. , Sakoff, Jennette A. , Scarlett, Christopher J. , McCluskey, Adam
- Resource Type: journal article
- Date: 2022
Amino Alcohols as Potential Antibiotic and Antifungal Leads
- Creator: Baker, Jennifer R. , Cossar, Peter J. , Blaskovich, Mark A. T. , Elliott, Alysha G. , Zuegg, Johannes , Cooper, Matthew A. , Lewis, Peter J. , McCluskey, Adam
- Resource Type: journal article
- Date: 2022
Antigiardial Activity of Novel Guanidine Compounds
- Creator: Stevens, Andrew J. , Abraham, Rebecca , Young, Kelly A. , Russell, Cecilia C. , McCluskey, Siobhann N. , Baker, Jennifer R. , Rusdi, Bertha , Page, Stephen W. , O'Handley, Ryan , O'Dea, Mark , Abraham, Sam , McCluskey, Adam
- Resource Type: journal article
- Date: 2022
Light-mediated multi-target protein degradation using arylazopyrazole photoswitchable PROTACs (AP-PROTACs)
- Creator: Zhang, Qisi , Kounde, Cyrille S. , De Vita, Elena , Kozakov, Dima , McCluskey, Adam , Harling, John D. , Fuchter, Matthew J. , Tate, Edward W. , Mondal, Milon , Greenfield, Jake L. , Baker, Jennifer R. , Kotelnikov, Sergei , Ignatov, Mikhail , Tinworth, Christopher P. , Zhang, Leran , Conole, Daniel
- Resource Type: journal article
- Date: 2022
Role of Clathrin and Dynamin in Clathrin Mediated Endocytosis/Synaptic Vesicle Recycling and Implications in Neurological Diseases
- Creator: Prichard, Kate L. , O'Brien, Nicholas S. , Murcia, Sari R. , Baker, Jennifer R. , McCluskey, Adam
- Resource Type: journal article
- Date: 2022
Amino alcohol acrylonitriles as broad spectrum and tumour selective cytotoxic agents
- Creator: Baker, Jennifer R. , Russell, Cecilia C. , Gilbert, Jayne , McCluskey, Adam , Sakoff, Jennette A.
- Resource Type: journal article
- Date: 2021
Cytotoxic 1,2,3-Triazoles as Potential Leads Targeting the S100A2-p53 Complex: Synthesis and Cytotoxicity
- Creator: Sun, Jufeng , Baker, Jennifer R. , Russell, Cecilia C. , Cossar, Peter J. , Ngoc Thuy Pham, Hong , Sakoff, Jennette A. , Scarlett, Christopher J. , McCluskey, Adam
- Resource Type: journal article
- Date: 2021
Development and interpretation of a QSAR model for in vitro breast cancer (MCF-7) cytotoxicity of 2-phenylacrylonitriles
- Creator: Stanton, David T. , Baker, Jennifer R. , McCluskey, Adam , Paula, Stefan
- Resource Type: journal article
- Date: 2021
Modelling and phenotypic screening of NAP-6 and 10-Cl-BBQ, AhR ligands displaying selective breast cancer cytotoxicity in vitro
- Creator: Baker, Jennifer R. , Pollard, Brett L. , Lin, Andrew J. S. , Gilbert, Jayne , Paula, Stefan , Zhu, Xiao , Sakoff, Jennette A. , McCluskey, Adam
- Resource Type: journal article
- Date: 2021
Targeting the S100A2-p53 Interaction with a Series of 3,5-Bis(trifluoromethyl)benzene Sulfonamides: Synthesis and Cytotoxicity
- Creator: Sun, Jufeng , Ambrus, Joey I. , Russell, Cecilia C. , Baker, Jennifer R. , Cossar, Peter J. , Pirinen, Melanie J. , Sakoff, Jennette A. , Scarlett, Christopher J. , McCluskey, Adam
- Resource Type: journal article
- Date: 2021
Amino alcohol acrylonitriles as activators of the aryl hydrocarbon receptor pathway: an unexpected MTT phenotypic screening outcome
- Creator: Baker, Jennifer R. , Russell, Cecilia C. , Gilbert, Jayne , Sakoff, Jennette A. , McCluskey, Adam
- Resource Type: journal article
- Date: 2020
Design and synthesis of arylhydrocarbon receptor ligands for the treatment of breast cancer
- Creator: Baker, Jennifer R.
- Resource Type: thesis
- Date: 2020
In vitro activity of robenidine analog NCL195 in combination with outer membrane permeabilizers against gram-negative bacterial pathogens and impact on systemic gram-positive bacterial infection in mice
- Creator: Pi, Hongfei , Nguyen, Hang Thi , Venter, Henrietta , Boileau, Alexandra R. , Woolford, Lucy , Garg, Sanjay , Page, Stephen W. , Russell, Cecilia C. , Baker, Jennifer R. , McCluskey, Adam , O'Donovan, Lisa A. , Trott, Darren J. , Ogunniyi, Abiodun D.
- Resource Type: journal article
- Date: 2020
The aryl hydrocarbon receptor (AhR) as a breast cancer drug target
- Creator: Baker, Jennifer R. , Sakoff, Jennette A. , McCluskey, Adam
- Resource Type: journal article
- Date: 2020
Binding of chlorinated phenylacrylonitriles to the aryl hydrocarbon receptor: computational docking and molecular dynamics simulations
- Creator: Paula, Stefan , Baker, Jennifer R. , Zhu, Xiao , McCluskey, Adam
- Resource Type: book chapter
- Date: 2019
Discovery of 4,6-bis(2-((E)-benzylidene)hydrazinyl)pyrimidin-2-amine with antibiotic activity
- Creator: Russell, Cecillia C. , Stevens, Andrew , McCluskey, Adam , Young, Kelly A. , Baker, Jennifer R. , McCluskey, Siobhann N. , Khazandi, Manouchehr , Pi, Hongfei , Ogunniyi, Abiodun , Page, Stephen W. , Trott, Darren J.
- Resource Type: journal article
- Date: 2019