Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors
- Creator: Smith, Amanda M. , Dun, Matthew D. , Toop, Hamish , Lock, Richard B. , Powell, Jason A. , Thomas, Daniel , Guthridge, Mark A. , Moore, Andrew , Ashman, Leonie K. , Skelding, Kathryn A. , Enjeti, Anoop , Verrills, Nicole M. , Lee, Erwin M. , Harrison, Celeste , Kahl, Richard , Flanagan, Hayley , Panicker, Nikita , Mashkani, Baratali , Don, Anthony S. , Morris, Jonathan
- Resource Type: journal article
- Date: 2016
An in vivo tumor model exploiting metabolic response as a biomarker for targeted drug development
- Creator: Cullinane, C. , Dorow, D. S. , Kansara, M. , Conus, N. , Binns, D. , Hicks, R. J. , Ashman, Leonie K. , McArthur, G. A. , Thomas, D. M.
- Resource Type: journal article
- Date: 2005
CD151 (CD151 molecule (Raph blood group))
- Creator: Weidenhofer, Judith , Ashman, Leonie K.
- Resource Type: journal article
- Date: 2009
Characterization of mice lacking the tetraspanin superfamily member CD151
- Creator: Wright, Mark D. , Geary, Sean M. , Fitter, Stephen , Moseley, Gregory W. , Lau, Lai-Man , Sheng, Kuo-Ching , Apostolopoulos, Vasso , Stanley, Edouard G. , Jackson, Denise E. , Ashman, Leonie K.
- Resource Type: journal article
- Date: 2004
Characterization of the early molecular changes in the glomeruli of Cd151-/- mice highlights induction of mindin and MMP-10
- Creator: Naudin, Crystal , Smith, Brian , Bond, Danielle R. , Dun, Matthew D. , Scott, Rodney J. , Ashman, Leonie K. , Weidenhofer, Judith , Roselli, Séverine
- Resource Type: journal article
- Date: 2017
Colocalization of the tetraspanins, CO-029 and CD151, with integrins in human pancreatic adenocarcinoma: Impact on cell motility
- Creator: Gesierich, S. , Paret, C. , Hildebrand, D. , Weitz, J. , Zgraggen, K. , Schmitz-Winnenthal, F. H. , Horejsi, V. , Yoshie, O. , Herlyn, D. , Ashman, Leonie K. , Zoller, M.
- Resource Type: journal article
- Date: 2005
Colony stimulating factor-1 receptor as a target for small molecule inhibitors
- Creator: Mashkani, Baratali , Griffith, Renate , Ashman, Leonie K.
- Resource Type: journal article
- Date: 2010
Deletion of Cd151 reduces mammary tumorigenesis in the MMTV/PyMT mouse model
- Creator: Roselli, Séverine , Kahl, Richard G. S. , Copeland, Ben T. , Naylor, Matthew J. , Weidenhofer, Judith , Muller, William J. , Ashman, Leonie K.
- Resource Type: journal article
- Date: 2014
Deletion of Cd151 results in a strain-dependent glomerular disease due to severe alterations of the glomerular basement membrane
- Creator: Baleato, Rosa , Guthrie, Petrina L. , Gubler, Marie-Claire , Ashman, Leonie K. , Roselli, Severine
- Resource Type: journal article
- Date: 2008
Essential requirement for PP2A inhibition by the oncogenic receptor c-KIT suggests PP2A reactivation as a strategy to treat c-KIT⁺ cancers
- Creator: Roberts, Kathryn G. , Smith, Amanda M. , Sim, Alistair T. R. , Ashman, Leonie K. , Verrills, Nicole M. , McDougall, Fiona , Carpenter, Helen , Horan, Martin , Neviani, Paolo , Powell, Jason A. , Thomas, Daniel , Guthridge, Mark A. , Perrotti, Danilo
- Resource Type: journal article
- Date: 2010
Evidence for the involvement of PECAM-1 in a receptor mediated signal-transduction pathway regulating capacitation-associated tyrosine phosphorylation in human spermatozoa
- Creator: Nixon, Brett , Paul, Jonathan W. , Spiller, Cassy M. , Attwell-Heap, Abigail G. , Ashman, Leonie K. , Aitken, R. John
- Resource Type: journal article
- Date: 2005
Expression of biologically active human colony stimulating factor-1 in Pichia pastoris
- Creator: Mashkani, Baratali , Odell, Adam F. , Byrnes, Ellen M. , Griffith, Renate , Ashman, Leonie K.
- Resource Type: journal article
- Date: 2013
FMS-like tyrosine kinase 3 (FLT3) inhibitors: molecular docking and experimental studies
- Creator: Mashkani, Baratali , Tanipour, Mohammad Hossein , Saadatmandzadeh, Mohammad , Ashman, Leonie K. , Griffith, Renate
- Resource Type: journal article
- Date: 2016
Genetic ablation of the tetraspanin CD151 reduces spontaneous metastatic spread of prostate cancer in the TRAMP model
- Creator: Copeland, Ben T. , Bowman, Matthew J. , Ashman, Leonie K.
- Resource Type: journal article
- Date: 2013
Identification of Tspan9 as a novel platelet tetraspanin and the collagen receptor GPVI as a component of tetraspanin microdomains
- Creator: Protty, Majd B. , Watkins, Nicholas A. , Ouwehand, Willem H. , Watson, Steve P. , Tomlinson, Michael G. , Colombo, Dario , Thomas, Steven G. , Heath, Victoria L. , Herbert, John M. J. , Bicknell, Roy , Senis, Yotis A. , Ashman, Leonie K. , Berditchevski, Fedor
- Resource Type: journal article
- Date: 2009
Juxtamembrane mutant V560GKit is more sensitive to Imatinib (ST1571) compared with wild-type c-Kit whereas the kinase domain mutant D816VKit is resistant
- Creator: Frost, Michelle J. , Ferrao, Petranel T. , Hughes, Timothy P. , Ashman, Leonie K.
- Resource Type: journal article
- Date: 2002
Knockout of the tetraspanin Cd9 in the TRAMP model of de novo prostate cancer increases spontaneous metastases in an organ-specific manner
- Creator: Copeland, Ben T. , Bowman, Matthew J. , Boucheix, Claude , Ashman, Leonie K.
- Resource Type: journal article
- Date: 2013
miR-518f-5p decreases tetraspanin CD9 protein levels and differentially affects non-tumourigenic prostate and prostate cancer cell migration and adhesion
- Creator: Bond, Danielle R. , Naudin, Crystal , Carroll, Adam P. , Goldie, Belinda J. , Brzozowski, Joshua S. , Jankowski, Helen M. , Cairns, Murray J. , Ashman, Leonie K. , Scarlett, Christopher J. , Weidenhofer, Judith
- Resource Type: journal article
- Date: 2018
Probing the interaction of tetraspanin CD151 with integrin α3β1 using a panel of monoclonal antibodies with distinct reactivities toward the CD151-integrin α3β1 complex
- Creator: Yamada, Masashi , Tamura, Yumiko , Sanzen, Noriko , Sato-Nishiuchi, Ryoko , Hasegawa, Hitoshi , Ashman, Leonie K. , Rubinstein, Eric , Yanez-Mo, Maria , Sanchez-Madrid, Francisco , Sekiguchi, Kiyotoshi
- Resource Type: journal article
- Date: 2008
Src family kinases are involved in the differential signaling from two splice forms of c-Kit
- Creator: Voytyuk, Olexandra , Lennartsson, Johan , Mogi, Akira , Caruana, Georgina , Courtneidge, Sara , Ashman, Leonie K. , Ronnstrand, Lars
- Resource Type: journal article
- Date: 2003