Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk
- Creator: Carvajal-Carmona, Luis G. , O Mara, Tracy A. , Pooley, Karen , Beesley, Jonathan , Cheng, Timothy , Jones, Angela , Howarth, Kimberley , Martin, Lynn , Gorman, Maggie , Hodgson, Shirley , National Study of Endometrial Cancer Genetics Group (NSECG) , . , The Australian National Endometrial Cancer Study Group (ANECS), . , Painter, Jodie N. , Wentzensen, Nicholas , Fasching, Peter A. , Hein, Alexander , Beckmann, Matthias W. , Renner, Stefan P. , Dörk, Thilo , Hillemanns, Peter , Dürst, Matthias , Runnebaum, Ingo , Lambrechts, Diether , Lose, Felicity A. , Coenegrachts, Lieve , Schrauwen, Stefanie , Amant, Frederic , Winterhoff, Boris , Dowdy, Sean C. , Goode, Ellen L. , Teoman, Attila , Salvesen, Helga B. , Trovik, Jone , Njolstad, Tormund S. , Dennis, Joe , Werner, Henrica M. J. , Scott, Rodney J. , Ashton, Katie , Proietto, Tony , Otton, Geoffrey , Wersäll, Ofra , Mints, Miriam , Tham, Emma , RENDOCAS, , Hall, Per , Michailidou, Kyriaki , Czene, Kamila , Liu, Jianjun , Li, Jingmei , Hopper, John L. , Southey, Melissa C. , Australian Ovarian Cancer Study (AOCS), . , Ekici, Arif B. , Ruebner, Matthias , Johnson, Nichola , Peto, Julian , Tyrer, Jonathan P. , Burwinkel, Barbara , Marme, Frederik , Brenner, Hermann , Dieffenbach, Aida K. , Meindl, Alfons , Brauch, Hiltrud , The GENICA Network, . , Lindblom, Annika , Depreeuw, Jeroen , Moisse, Matthieu , Ahmed, Shahana , Chang-Claude, Jenny , Rudolph, Anja , Couch, Fergus J. , Olson, Janet E. , Giles, Graham G. , Bruinsma, Fiona , Cunningham, Julie M. , Fridley, Brooke L. , Børresen-Dale, Anne-Lise , Kristensen, Vessela N. , Ferguson, Kaltin , Cox, Angela , Swerdlow, Anthony J. , Orr, Nicholas , Bolla, Manjeet K. , Wang, Qin , Palmieri Weber, Rachel , Chen, Zhihua , Shah, Mitul , Pharoah, Paul D. P. , Dunning, Alison M. , Healey, Catherine S. , Tomlinson, Ian , Easton, Douglas F. , Spurdle, Amanda B. , Thompson, Deborah J.
- Resource Type: journal article
- Date: 2015
Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer
- Creator: O'Mara, Tracy A. , Glubb, Dylan M. , Ashton, Katie , Proietto, Tony , Otton, Geoffrey , Shah, Mitul , Ahmed, Shahana , Healey, Catherine S. , Gorman, Maggie , Martin, Lynn , National Study of Endometrial Cancer Genetics Group (NSECG), , Hodgson, Shirley , Painter, Jodie N. , Fasching, Peter A. , Hein, Alexander , Beckmann, Matthias W. , Ekici, Arif B. , Hall, Per , Czene, Kamila , Darabi, Hatef , Li, Jingmei , Dürst, Matthias , Runnebaum, Ingo , Cheng, Timothy , Hillemanns, Peter , Dörk, Thilo , Lambrechts, Diether , Depreeuw, Jeroen , Annibali, Daniela , Amant, Frederic , Zhao, Hui , Goode, Ellen L. , Dowdy, Sean C. , Fridley, Brooke L. , Dennis, Joe , Winham, Stacey J. , Salvesen, Helga B. , Njølstad, Tormund S. , Trovik, Jone , Werner, Henrica M. J. , Tham, Emma , Liu, Tao , Mints, Miriam , RENDOCAS, , Bolla, Manjeet K. , Australian National Endometrial Cancer Study Group (ANECS), , Michailidou, Kyriaki , Tyrer, Jonathan P. , Wang, Qin , Hopper, John L. , AOCS Group, , Peto, Julian , Swerdlow, Anthony J. , Burwinkel, Barbara , Brenner, Hermann , Meindl, Alfons , Attia, John , Brauch, Hiltrud , Lindblom, Annika , Chang-Claude, Jenny , Couch, Fergus J. , Giles, Graham G. , Kristensen, Vessela N. , Cox, Angela , Pharoah, Paul D. P. , Dunning, Alison M. , Tomlinson, Ian , Holliday, Elizabeth G. , Easton, Douglas F. , Thompson, Deborah J. , Spurdle, Amanda B. , McEvoy, Mark , Scott, Rodney J.
- Resource Type: journal article
- Date: 2015
Cross-Cancer Genome-Wide Association Study of Endometrial Cancer and Epithelial Ovarian Cancer Identifies Genetic Risk Regions Associated with Risk of Both Cancers
- Creator: Glubb, Dylan M. , Thompson, Deborah J. , Bermisheva, Marina , McNeish, IA , Menon, U , Modugno, F , Moysich, KB , Nevanlinna, H , Odunsi, K , Olsson, H , Orsulic, S , Osorio, A , Palli, D , Bernardini, Marcus Q. , Park-Simon, T-W , Pearce, CL , Pejovic, T , Permuth, JB , Podgorska, A , Ramus, SJ , Rebbeck, TR , Riggan, MJ , Risch, HA , Rothstein, JH , Bischof, Katharina , Runnebaum, IB , Scott, RJ , Sellers, TA , Senz, J , Setiawan, VW , Siddiqui, N , Sieh, W , Spiewankiewicz, B , Sutphen, R , Swerdlow, AJ , Bjorge, Line , Szafron, LM , Teo, SH , Thompson, PJ , Thomsen, LCV , Titus, L , Tone, A , Tumino, R , Turman, C , Vanderstichele, A , Edwards, DV , Bodelon, Clara , Vergote, I , Vierkant, RA , Wang, Z , Wang-Gohrke, S , Webb, PM , White, E , Whittemore, AS , Winham, SJ , Wu, X , Wu, AH , Brand, Alison H. , Yannoukakos, D , Spurdle, AB , O'Mara, TA , Brenton, James D. , Brinton, Louise A. , Bruinsma, Fiona , Buchanan, Daniel D. , Aben, Katja K. H. , Burghaus, S , Butzow, R , Cai, H , Carney, ME , Chanock, SJ , Chen, C , Chen, XQ , Chen, Z , Cook, LS , Cunningham, JM , Alsulimani, Ahmad , De Vivo, I , DeFazio, A , Doherty, JA , Dork, T , du Bois, A , Dunning, AM , Durst, M , Edwards, T , Edwards, RP , Ekici, AB , Amant, Frederic , Ewing, A , Fasching, PA , Ferguson, S , Flanagan, JM , Fostira, F , Fountzilas, G , Friedenreich, CM , Gao, B , Gaudet, MM , Gawelko, J , Annibali, Daniela , Gentry-Maharaj, A , Giles, GG , Glasspool, R , Goodman, MT , Gronwald, J , Harris, HR , Harter, P , Hein, A , Heitz, F , Hildebrandt, MAT , Attia, John , Hillemanns, P , Hogdall, E , Hogdall, CK , Holliday, Elizabeth G. , Huntsman, DG , Huzarski, T , Jakubowska, A , Jensen, A , Jones, ME , Karlan, BY , Barricarte, Aurelio , Karnezis, A , Kelley, JL , Khusnutdinova, E , Killeen, JL , Kjaer, SK , Klapdor, R , Kobel, M , Konopka, B , Konstantopoulou, I , Kopperud, RK , Beckmann, Matthias W. , Koti, M , Kraft, P , Kupryjanczyk, J , Lambrechts, D , Larson, MC , Le Marchand, L , Lele, S , Lester, J , Li, AJ , Liang, D , Berchuck, Andrew , Liebrich, C , Lipworth, L , Lissowska, J , Lu, L , Lu, KH , Macciotta, A , Mattiello, A , May, T , McAlpine, JN , McGuire, V
- Resource Type: journal article
- Date: 2021
Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk.
- Creator: Painter, Jodie N. , O'Mara, Tracy A. , Healey, Catherine S. , Fridley, Brooke L. , Børresen-Dale, Anne-Lise , Kristensen, Vessela N. , Cox, Angela , Swerdlow, Anthony J. , Orr, Nicholas , Bolla, Manjeet K. , Wang, Qin , Palmieri Weber, Rachel , Chen, Zhihua , Kaufmann, Susanne , Shah, Mitul , French, Juliet D. , Pharoah, Paul D. P. , Dunning, Alison M. , Tomlinson, Ian , Easton, Douglas F. , Edwards, Stacey L. , Thompson, Deborah J. , Spurdle, Amanda B. , Hillman, Kristine M. , Walpole, Carina , Moya, Leire , Pollock, Pamela , Jones, Angela , Howarth, Kimberley , Martin, Lynn , Gorman, Maggie , Batra, Jyotsna , Hodgson, Shirley , National Study of Endometrial Cancer Genetics Group (NSECG) , CHIBCHA Consortium , De Polanco, Ma. Magdalena Echeverry , Sans, Monica , Carracedo, Angel , Castellvi-Bel, Sergi , Rojas-Martinez, Augusto , Santos, Erika , Teixeira, Manuel R. , Cheng, Timothy , Carvajal-Carmona, Luis , Shu, Xiao-Ou , Long, Jirong , Zheng, Wei , Xiang, Yong-Bing , The Australian National Endometrial Cancer Study Group (ANECS) , Montgomery, Grant W. , Webb, Penelope M. , Scott, Rodney J. , McEvoy, Mark , Lose, Felicity A. , Attia, John , Holliday, Elizabeth , Martin, Nicholas G. , Nyholt, Dale R. , Henders, Anjali K. , Fasching, Peter A. , Hein, Alexander , Beckmann, Matthias W. , Renner, Stefan P. , Dörk, Thilo , Dennis, Joe , Hillemanns, Peter , Dürst, Matthias , Runnebaum, Ingo , Lambrechts, Diether , Coenegrachts, Lieve , Schrauwen, Stefanie , Amant, Frederic , Winterhoff, Boris , Dowdy, Sean C. , Goode, Ellen L. , Michailidou, Kyriaki , Teoman, Attila , Salvesen, Helga B. , Trovik, Jone , Njolstad, Tormund S. , Werner, Henrica M. J. , Ashton, Katie , Proietto, Tony , Otton, Geoffrey , Tzortzatos, Gerasimos , Mints, Miriam , Tyrer, Jonathan P. , Tham, Emma , RENDOCAS , Hall, Per , Czene, Kamila , Liu, Jianjun , Li, Jingmei , Hopper, John L. , Southey, Melissa C. , Australian Ovarian Cancer Study (AOCS) , Ekici, Arif B. , Ahmed, Shahana , Ruebner, Matthias , Johnson, Nicola , Peto, Julian , Burwinkel, Barbara , Marme, Frederik , Brenner, Hermann , Dieffenbach, Aida K. , Miendl, Alfons , Brauch, Hiltrud , The GENICA Network, , Ferguson, Kaltin , Lindblom, Annika , Depreeuw, Jeroen , Moisse, Matthieu , Chang-Claude, Jenny , Rudolph, Anja , Couch, Fergus J. , Olsen, Janet E. , Giles, Graham G. , Bruinsma, Fiona , Cunnigham, Julie M.
- Resource Type: journal article
- Date: 2015
Genetic risk score mendelian randomization shows that obesity measured as body mass index, but not waist:hip ratio, is causal for endometrial cancer
- Creator: Painter, Jodie N. , O'Mara, Tracy A. , Scott, Rodney J. , Ahmed, Shahana , Healey, Catherine S. , Shah, Mitul , Gorman, Maggie , Martin, Lynn , Hodgson, Shirley V. , Beckmann, Matthias W. , Ekici, Arif B. , Fasching, Peter A. , Marquart, Louise , Hein, Alexander , Rübner, Matthias , Czene, Kamilla , Darabi, Hatef , Hall, Per , Li, Jingmei , Dörk, Thilo , Dürst, Matthias , Hillemanns, Peter , Runnebaum, Ingo B. , Webb, Penelope M. , Amant, Frederic , Annibali, Daniela , Depreeuw, Jeroen , Lambrechts, Diether , Neven, Patrick , Cunningham, Julie M. , Dowdy, Sean C. , Goode, Ellen L. , Fridley, Brooke L. , Winham, Stacey J. , Attia, John , Njølstad, Tormund S. , Salvesen, Helga B. , Trovik, Jone , Werner, Henrica M. J. , Ashton, Katie A. , Otton, Geoffrey , Proietto, Anthony , Mints, Miriam , Tham, Emma , Bolla, Manjeet K. , Medland, Sarah E. , Michailidou, Kyriaki , Wang, Qin , Tyrer, Jonathan P. , Hopper, John L. , Peto, Julian , Swerdlow, Anthony J. , Burwinkel, Barbara , Brenner, Hermann , Meindl, Alfons , Brauch, Hiltrud , Cheng, Timothy , Lindblom, Annika , Chang-Claude, Jenny , Couch, Fergus J. , Giles, Graham G. , Kristensen, Vessela N. , Cox, Angela , Pharoah, Paul D. P. , Tomlinson, Ian , Dunning, Alison M. , Easton, Douglas F. , Dennis, Joe , Thompson, Deborah J. , Spurdle, Amanda B. , Holliday, Elizabeth G. , McEvoy, Mark
- Resource Type: journal article
- Date: 2016
Genome-wide association study identifies a common variant associated with risk of endometrial cancer
- Creator: Spurdle, Amanda B. , Thompson, Deborah J. , Fahey, Paul , Montgomery, Grant W. , Webb, Penelope M. , Fasching, Peter A. , Beckmann, Matthias W. , Ekici, Arif B. , Hein, Alexander , Lambrechts, Diether , Coenegrachts, Lieve , Vergote, Ignace , Ahmed, Shahana , Amant, Frederic , Salvesen, Helga B. , Trovik, Jone , Njolstad, Tormund S. , Helland, Harald , Scott, Rodney J. , Ashton, Katie , Proietto, Tony , Otton, Geoffrey , National Study of Endometrial Cancer Genetics Group, , Ferguson, Kaltin , Tomlinson, Ian , Gorman, Maggie , Howarth, Kimberley , Hodgson, Shirley , Garcia-Closas, Montserrat , Wentzensen, Nicolas , Yang, Hannah , Chanock, Stephen , Hall, Per , Czene, Kamila , Healey, Catherine S. , Liu, Jianjun , Li, Jingmei , Shu, Xiao-Ou , Zheng, Wei , Long, Jirong , Xiang, Yong-Bing , Shah, Mitul , Morrison, Jonathan , Michailidou, Kyriaki , Pharoah, Paul D. , O'Mara, Tracy , Dunning, Alison M. , Easton, Douglas F. , Walker, Logan C, , Montgomery, Stephen B. , Dermitzakis, Emmanouil T. , Australian National Endometrial Cancer Study Group,
- Resource Type: journal article
- Date: 2011
Genome-wide association study identifies a possible susceptibility locus for endometrial cancer
- Creator: Long, Jirong , Zheng, Wei , Dubrowinskaja, Natalia , Goodman, Marc T. , Salvesen, Helga B. , Fasching, Peter A. , Scott, Rodney J. , Delahanty, Ryan , Zheng, Ying , O'Mara, Tracy , Healey, Catherine S. , Hodgson, Shirley , Xiang, Yong-Bing , Risch, Harvey , Yang, Hannah P. , Amant, Frederic , Turmanov, Nurzhan , Schwake, Anita , Lurie, Galina , Trovik, Jone , Beckmann, Matthias W. , Ashton, Katie , Ji, Bu-Tian , Lose, Felicity , Bao, Ping-Ping , Howarth, Kimberly , Lu, Lingeng , Lissowska, Jolanta , Coenegrachts, Lieve , Kaidarova, Dilyara , Dürst, Matthias , Thompson, Pamela J. , Krakstad, Camilla , Ekici, Arif B. , Thompson, Deborah , Otton, Geoffrey , Shi, Jiajun , Zhang, Ben , Gorman, Maggie , Brinton, Louise , Coosemans, An , Matsuno, Rayna K. , Halle, Mari K. , Hein, Alexander , Proietto, Anthony , Tomlinson, Ian , Cai, Hui , Lu, Wei , Dunning, Alison , Easton, Douglas , Gao, Yu-Tang , Cai, Qiuyin , Spurdle, Amanda B. , Shu, Xiao-Ou , Yu, Herbert , Wentzensen, Nicholas , Lambrechts, Diether , Dörk, Thilo
- Resource Type: journal article
- Date: 2012
Identification of nine new susceptibility loci for endometrial cancer
- Creator: O'Mara, Tracy A. , Glubb, Dylan M. , Amant, Frederic , Annibali, Daniela , Ashton, Katie , Attia, John , Auer, Paul L. , Beckmann, Matthias W. , Black, Amanda , Bolla, Manjeet K. , Brauch, Hiltrud , Brenner, Hermann , Brinton, Louise , Buchanan, Daniel D. , Burwinkel, Barbara , Chang-Claude, Jenny , Chanock, Stephen J. , Chen, Chu , Chen, Maxine M. , Cheng, Timothy H. T. , Clarke, Christine L. , Holliday, Elizabeth G. , McEvoy, Mark , Otton, Geoffrey , Proietto, Tony , Scott, Rodney J.
- Resource Type: journal article
- Date: 2018
Mendelian randomization analyses suggest a role for cholesterol in the development of endometrial cancer
- Creator: Kho, Pik-Fang , Amant, Frederic , Annibali, Daniela , Ashton, Katie , Attia, John , Auer, Paul L. , Beckmann, Matthias W. , Black, Amanda , Brinton, Louise , Buchanan, Daniel D. , Chanock, Stephen J. , Chen, Chu , Chen, Maxine M. , Cheng, Timothy H. T. , Cook, Linda S. , Crous-Bous, Marta , Czene, Kamila , De Vivo, Immaculata , Dennis, Joe , Döerk, Thilo , Holliday, Elizabeth G. , McEvoy, Mark , Otton, Geoffrey , Proietto, Tony , Scott, Rodney J. , Dowdy, Sean C. , Dunning, AM , Duerst, M , Easton, DF , Ekici, AB , Fasching, PA , Fridley, BL , Friedenreich, CM , Garcia-Closas, M , Gaudet, MM , Giles, GG , Goode, EL , Gorman, M , Haiman, CA , Hall, P , Hankinson, SE , Hein, A , Hillemanns, P , Hodgson, S , Hoivik, EA , Hunter, DJ , Jones, A , Kraft, P , Krakstad, C , Lambrechts, D , Le Marchand, L , Liang, X , Lindblom, A , Lissowska, J , Long, J , Lu, L , Magliocco, AM , Martin, L , Milne, RL , Mints, M , Nassir, R , Palles, C , Pooler, L , Rebbeck, TR , Renner, SP , Risch, HA , Ruebner, M , Runnebaum, I , Sacerdote, C , Sarto, GE , Schumacher, F , Setiawan, VW , Shah, M , Sheng, X , Shu, X-O , Southey, MC , Tham, E , Tomlinson, I , Trovik, J , Turman, C , Tyrer, JP , van den Berg, D , Wang, Z , Wentzensen, N , Xia, L , Xiang, Y-B , Yang, HP , Yu, H , Zheng, W , Webb, PM , Thompson, DJ , Spurdle, AB , Glubb, DM , O'Mara, TA
- Resource Type: journal article
- Date: 2020
Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1
- Creator: Cheng, Timothy H. T. , Thompson, Deborah , Hopper, John , Tomlinson, Ian , Jenkins, Mark , Lindor, Noralane M. , Newcomb, Polly A. , Gallinger, Steve , Conti, David , Schumacher, Fred , Casey, Graham , Giles, Graham G. , Pharoah, Paul , Painter, Jodie , Peto, Julian , Cox, Angela , Swerdlow, Anthony , Couch, Fergus , Cunningham, Julie M. , Goode, Ellen L. , Winham, Stacey J. , Lambrechts, Diether , Fasching, Peter , Burwinkel, Barbara , O'Mara, Tracy , Brenner, Hermann , Brauch, Hiltrud , Chang-Claude, Jenny , Salvesen, Helga B. , Kristensen, Vessela , Darabi, Hatef , Li, Jingmei , Liu, Tao , Lindblom, Annika , Hall, Per , Gorman, Maggie , de Polanco, Magdalena Echeverry , Sans, Monica , Carracedo, Angel , Castellvi-Bel, Sergi , Rojas-Martinez, Augusto , Aguiar Jnr, Samuel , Teixeira, Manuel R. , Dunning, Alison M. , Dennis, Joe , Otton, Geoffrey , Martin, Lynn , Proietto, Tony , Holliday, Elizabeth , Attia, John , Ashton, Katie , Scott, Rodney J. , McEvoy, Mark , Dowdy, Sean C. , Fridley, Brooke L. , Werner, Henrica M. J. , Trovik, Jone , Palles, Claire , Njolstad, Tormund S. , Tham, Emma , Mints, Miriam , Runnebaum, Ingo , Hillemanns, Peter , Dörk, Thilo , Amant, Frederic , Schrauwen, Stefanie , Hein, Alexander , Beckmann, Matthias W. , Jones, Angela , Ekici, Arif , Czene, Kamila , Meindl, Alfons , Bolla, Manjeet K. , Michailidou, Kyriaki , Tyrer, Jonathan P. , Wang, Qin , Ahmed, Shahana , Healey, Catherine S. , Shah, Mitul , Buchanan, Daniel D. , Annibali, Daniela , Depreeuw, Jeroen , Al-Tassan, Nada A. , Harris, Rebecca , Meyer, Brian F. , Whiffin, Nicola , Hosking, Fay J. , Kinnersley, Ben , Farrington, Susan M. , Timofeeva, Maria , Ko Win, Aung , Tenesa, Albert , Campbell, Harry , Haile, Robert W. , Hodgson, Shirley , Carvajal-Carmona, Luis , Cheadle, Jeremy P. , Easton, Douglas , Dunlop, Malcolm , Houlston, Richard , Spurdle, Amanda
- Resource Type: journal article
- Date: 2015
Multi-trait genome-wide association study identifies a novel endometrial cancer risk locus that associates with testosterone levels
- Creator: Wang, Xuemin , Kho, Pik Fang , Dörk, Thilo , Spurdle, Amanda B. , Glubb, Dylan M. , O'Mara, Tracy A. , Ramachandran, Dhanya , Bafligil, Cemsel , Amant, Frederic , Goode, Ellen L. , Scott, Rodney J. , Tomlinson, Ian , Evans, D. Gareth , Crosbie, Emma J.
- Resource Type: journal article
- Date: 2023
PARAGON: a phase II study of anastrozole in patients with estrogen receptor-positive recurrent/metastatic low-grade ovarian cancers and serous borderline ovarian tumors
- Creator: Tang, Monica , O'Connell, Rachel L. , Amant, Frederic , Beale, Philip , McNally, Orla , Sjoquist, Katrin M. , Grant, Peter , Davis, Alison , Sykes, Peter , Mileshkin, Linda , Moujaber, Tania , Kennedy, Catherine J. , deFazio, Anna , Tan, King , Antill, Yoland , Goh, Jeffrey , Bonaventura, Tony , Scurry, James , Friedlander, Michael
- Resource Type: journal article
- Date: 2019