Luminal Ca²⁺ activation of cardiac ryanodine receptors by luminal and cytoplasmic domains
The ryanodine receptor pore blocker neomycin also inhibits channel activity via a previously undescribed high-affinity Ca²⁺ binding site
- Laver, Derek R., Hamada, Tomoyo, Fessenden, James D., Ikemoto, Noriaki
A domain peptide of the cardiac ryanodine receptor regulates channel sensitivity to luminal Ca²⁺ via cytoplasmic Ca²⁺ sites
- Laver, Derek R., Honen, Bonny N., Lamb, Graham D., Ikemoto, Noriaki
Ca²⁺ stores regulate ryanodine receptor Ca²⁺ release channels via luminal and cytosolic Ca²⁺ sites
The emerging role of calmodulin regulation of RyR2 in controlling heart rhythm, the progression of heart failure and the antiarrhythmic action of dantrolene
- Walweel, Kafa, Oo, Ye Win, Laver, Derek R.
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