A young testicular microenvironment protects Leydig cells against age-related dysfunction in a mouse model of premature aging

- Curley, Michael, Milne, Laura, Smith, Sarah, Jørgensen, Anne, Frederiksen, Hanne, Hadoke, Patrick, Potter, Paul, Smith, Lee B.

Leukemia inhibitory factor-receptor is dispensable for prenatal testis development but is required in sertoli cells for normal spermatogenesis in mice

- Curley, Michael, Milne, Laura, Smith, Sarah, Atanassova, Nina, Rebourcet, Diane, Darbey, Annalucia, Hadoke, Patrick W. F., Wells, Sara, Smith, Lee B.

Human Adipose-derived pericytes display steroidogenic lineage potential in vitro and influence Leydig cell regeneration in vivo in rats

- Curley, Michael, Gonzalez, Zaniah N., Milne, Laura, Hadoke, Patrick, Handel, Ian, Péault, Bruno, Smith, Lee B.

Leukemia inhibitory factor-receptor signalling negatively regulates gonadotrophin-stimulated testosterone production in mouse Leydig Cells: LIFR Signalling in Leydig Cells

- Curley, Michael, Darbey, Annalucia, O'Donnell, Liza, Kilcoyne, Karen R., Wilson, Kirsten, Mungall, Will, Rebourcet, Diane, Guo, Jingtao, Mitchell, Rod T., Smith, Lee B.

A comparison of in vivo viral targeting systems identifies adeno-associated virus serotype 9 (AAV9) as an effective vector for genetic manipulation of Leydig cells in adult mice

- Darbey, Annalcuia, Rebourcet, Diane, Curley, Michael, Kilcoyne, Karen, Jeffery, Nathan, Reed, Natalie, Milne, Laura, Roesl, Cornelia, Brown, Pamela, Smith, Lee B.

Deliverable transgenics & gene therapy possibilities for the testes

- Darbey, Annalucia, Smith, Lee B.

Androgen receptor is dispensable for x-zone regression in the female adrenal but regulates post-partum corticosterone levels and protects cortex integrity

- Gannon, Anne-Louise, O'Hara, Laura, Mason, Ian J., Jørgensen, Anne, Frederiksen, Hanne, Curley, Michael, Milne, Laura, Smith, Sarah, Mitchell, Rod T., Smith, Lee B.

Androgen receptor signalling in the male adrenal facilitates X-zone regression, cell turnover and protects against adrenal degeneration during ageing

- Gannon, Anne-Louise, O'Hara, Laura, Mason, J. Ian, Jørgensen, Anne, Frederiksen, Hanne, Milne, Laura, Smith, Sarah, Mitchell, Rod T., Smith, Lee B.

Ablation of glucocorticoid receptor in the hindbrain of the mouse provides a novel model to investigate stress disorders

- Gannon, Anne-Louise, O'Hara, Laura, Mitchell, Rod T., Smith, Lee B., Mason, J. Ian, Rebourcet, Diane, Smith, Sarah, Traveres, Adriana, Alcaide-Corral, Carlos Jose, Frederiksen, Hanne, Jorgensen, Anne, Milne, Laura

Exogenous gonadotrophin stimulation induces partial maturation of human sertoli cells in a testicular xenotransplantation model for fertility preservation

- Hutka, Marsida, Smith, Lee B., Goossens, Ellen, Wallace, W. Hamish B., Stukenborg, Jan-Bernd, Mitchell, Rod T.

Xenotransplantation as a model for human testicular development

- Hutka, Marsida, Smith, Lee B., Mitchell, Rod T.

Fertility preservation in childhood cancer: endocrine activity in prepubertal human testis xenografts exposed to a pubertal hormone environment

- Hutka, Marsida, Kadam, Prashant, Van Saen, Dorien, Homer, Natalie Z. M., Onofre, Jaime, Wallace, W. Hamish B., Smith, Lee B., Stukenborg, Jan-Bernd, Goossens, Ellen, Mitchell, Rod T.

Bi-allelic recessive loss-of-function variants in FANCM cause non-obstructive azoospermia

- Kasak, Laura, Punab, Margus, Smith, Lee B., Conrad, Donald F., Laan, Maris, Nagirnaja, Liina, Grigorova, Marina, Minajeva, Ave, Lopes, Alexandra M., Punab, Anna Maria, Aston, Kenneth I., Carvalho, Filipa, Laasik, Eve

A graphical and computational modeling platform for biological pathways

- Livigni, Alessandra, O'Hara, Laura, Polak, Marta E., Angus, Tim, Wright, Derek W., Smith, Lee B., Freeman, Tom C.

DMRT1 repression using a novel approach to genetic manipulation induces testicular dysgenesis in human fetal gonads

- Macdonald, Joni, Kilcoyne, Karen R., Sharpe, Richard M., Kavanagh, Áine, Anderson, Richard A., Brown, Pamela, Smith, Lee B., Jørgensen, Anne, Mitchell, Rod T.

Insulin and IGF1 receptors are essential for the development and steroidogenic function of adult Leydig cells

- Neirijnck, Yasmine, Calvel, Pierre, Smith, Lee B., Nef, Serge, Kilcoyne, Karen R., Kühne, Françoise, Stévant, Isbelle, Griffeth, Richard J., Pitetti, Jean-Lüc, Andric, Silvana A., Hu, Meng-Chun, Pralong, François

Sperm proteins and cancer-testis antigens are released by the seminiferous tubules in mice and men

- O'Donnell, Liza, Rebourcet, Diane, Hobbs, Robin M., McLachlan, Robert I., Webb, Andrew I., Pilatz, Adrian, Diemer, Thorsten, Smith, Lee B., Stanton, Peter G., Dagley, Laura F., Sgaier, Raouda, Infusini, Giuseppe, O'Shaughnessy, Peter J., Chalmel, Frederic, Fietz, Daniela, Weidner, Wolfgang, Legrand, Julien M. D.

Sertoli cells as key drivers of testis function

- O'Donnell, Liza, Smith, Lee B., Rebourcet, Diane

Modelling steroidogenesis: a framework model to support hypothesis generation and testing across endocrine studies

- O'Hara, Laura, O'Shaughnessy, Peter J., Freeman, Tom C., Smith, Lee B.

Characterisation of a mural cell network in the murine pituitary gland

- O'Hara, Laura, Christian, Helen C., Jeffery, Nathan, Le Tissier, Paul, Smith, Lee B.