The importance of canonical and alternate androgen production pathways in masculinisation, fertility and lifelong male health
- Creator: Lawrence, Ben Milton
- Resource Type: thesis
- Date: 2024
A Novel Model Using AAV9-Cre to Knockout Adult Leydig Cell Gene Expression Reveals a Physiological Role of Glucocorticoid Receptor Signalling in Leydig Cell Function
- Creator: Gannon, Anne-Louise , Darbey, Annalucia L. , Rebourcet, Diane , Chensee, Grace , Lawrence, Ben M. , O'Donnell, Liza , Kelso, Joanna , Reed, Natalie , Parameswaran, Shanmathi , Smith, Sarah , Smith, Lee B.
- Resource Type: journal article
- Date: 2022
New Insights into Testosterone Biosynthesis: Novel Observations from HSD17B3 Deficient Mice
- Creator: Lawrence, Ben M. , O'Donnell, Liza , Smith, Lee B. , Rebourcet, Diane
- Resource Type: journal article
- Date: 2022
Ablation of the canonical testosterone production pathway via knockout of the steroidogenic enzyme HSD17B3, reveals a novel mechanism of testicular testosterone production
- Creator: Rebourcet, Diane , Mackay, Rosa , Darbey, Annalucia , Curley, Michael K. , Jørgensen, Anne , Frederiksen, Hanne , Mitchell, Rod T. , O'Shaughnessy, Peter J. , Nef, Serge , Smith, Lee B.
- Resource Type: journal article
- Date: 2020
Androgen receptor signalling in the male adrenal facilitates X-zone regression, cell turnover and protects against adrenal degeneration during ageing
- Creator: Gannon, Anne-Louise , O'Hara, Laura , Mason, J. Ian , Jørgensen, Anne , Frederiksen, Hanne , Milne, Laura , Smith, Sarah , Mitchell, Rod T. , Smith, Lee B.
- Resource Type: journal article
- Date: 2019
Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero
- Creator: Warrington, Nicole M. , Shevroja, Enisa , Hemani, Gibran , Hysi, Pirro G. , Jiang, Yunxuan , Auton, Adam , Boer, Cindy G. , Mangino, Massimo , Wang, Carol A. , Kemp, John P. , McMahon, George , Medina-Gomez, Carolina , Hickey, Martha , Trajanoska, Katerina , Wolke, Dieter , Ikram, M. Arfan , The 23and Me Research Team , Montgomery, Grant W. , Felix, Janine F. , Wright, Margaret J. , Pennell, Craig E.
- Resource Type: journal article
- Date: 2018