ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines.

- Lozinski, Mathew, Bowden, Nikola A., Graves, Moira C., Fay, Michael, Day, Bryan W., Stringer, Brett W., Tooney, Paul A.

Bladder cancer survival in patients with NOD2 or CDKN2A variants

- Złowocka-Perłowska, Elżbieta, van de Wetering, Thierry, Tołoczko-Grabarek, Aleksandra, Scott, Rodney J., Lubiński, Jan

ASIC1 and ASIC3 mediate cellular senescence of human nucleus pulposus mesenchymal stem cells during intervertebral disc degeneration.

- Ding, Jingyu, Zhang, Renjie, Li, Huimin, Ji, Qiang, Cheng, Xiaomin, Thorne, Rick Francis, Hondermarck, Hubert, Liu, Xiaoying, Shen, Cailiang

Low tumour-infiltrating lymphocyte density in primary and recurrent glioblastoma

- Maddison, Kelsey, Graves, Moira C., Bowden, Nikola A., Fay, Michael, Vilain, Ricardo E., Faulkner, Sam, Tooney, Paul A.

miR-518f-5p decreases tetraspanin CD9 protein levels and differentially affects non-tumourigenic prostate and prostate cancer cell migration and adhesion

- Bond, Danielle R., Naudin, Crystal, Carroll, Adam P., Goldie, Belinda J., Brzozowski, Joshua S., Jankowski, Helen M., Cairns, Murray J., Ashman, Leonie K., Scarlett, Christopher J., Weidenhofer, Judith

BRAF/MEK inhibitors promote CD47 expression that is reversible by ERK inhibition in melanoma

- Liu, Fen, Jiang, Chen Chen, Thorne, Rick F., Jin, Lei, Wang, Qi, Zhang, Xu Dong, Yan, Xu Guang, Tseng, Hsin-Yi, Wang, Chun Yan, Zhang, Yuan Yuan, Yari, Hamed, La, Ting, Farrelly, Margaret, Guo, Su Tang

A novel compound which sensitizes BRAF wild-type melanoma cells to vemurafenib in a TRIM16-dependent manner

- Sutton, Selina K., Carter, Daniel R., McArthur, Grant A., Cheung, Belamy B., Marshall, Glenn M., Kim, Patrick, Tan, Owen, Arndt, Greg M., Zhang, Xu Dong, Baell, Jonathan, Noll, Benjamin D., Wang, Shudong, Kumar, Naresh

Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors

- Smith, Amanda M., Dun, Matthew D., Toop, Hamish, Lock, Richard B., Powell, Jason A., Thomas, Daniel, Guthridge, Mark A., Moore, Andrew, Ashman, Leonie K., Skelding, Kathryn A., Enjeti, Anoop, Verrills, Nicole M., Lee, Erwin M., Harrison, Celeste, Kahl, Richard, Flanagan, Hayley, Panicker, Nikita, Mashkani, Baratali, Don, Anthony S., Morris, Jonathan

Identification of the microRNA networks contributing to macrophage differentiation and function

- Zhou, Hong, Zhang, Jie, Eyers, Fiona, Xiang, Yang, Herbert, Cristan, Tay, Hock L., Foster, Paul S., Yang, Ming

ProNGF is a potential diagnostic biomarker for thyroid cancer

- Faulkner, Sam, Roselli, Severine, Demont, Yohann, Pundavela, Jay, Choquet, Genevieve, Leissner, Philippe, Oldmeadow, Christopher, Attia, John, Walker, Marjorie M., Hondermarck, Hubert

Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922

- Wang, Chun Yan, Guo, Su Tang, Jin, Lei, Zhang, Xu Dong, Jiang, Chen Chen, Wang, Jia Yu, Yan, Xu Guang, Farrelly, Margaret, Zhang, Yuan Yuan, Liu, Fen, Yari, Hamed, La, Ting, Lei, Fu Xi

The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinone-containing compounds and anti-microtubule drugs

- Liu, Pei Y., Sokolowski, Nicholas, Liu, Bing, Yang, Rui H., Guo, Xiang Y., Tee, Andrew E., Itoh, Ken, Wang, Jenny, Kavallaris, Maria, Haber, Michelle, Norris, Murray D., Cheung, Belamy B., Guo, Su T., Byrne, Jennifer A., Ziegler, David S., Marshall, Glenn M., Dinger, Marcel E., Codd, Rachel, Zhang, Xu D., Liu, Tao, Siddiqi, Faraz, Atmadibrata, Bernard, Telfer, Thomas J., Sun, Yuting, Zhang, Lihong, Yu, Denise, Mccarroll, Joshua

Sortilin is associated with breast cancer aggressiveness and contributes to tumor cell adhesion and invasion

- Roselli, Séverine, Pundavela, Jay, Demont, Yohann, Faulkner, Sam, Keene, Sheridan, Attia, John, Jiang, Chen Chen, Zhang, Xu Dong, Walker, Marjorie M., Hondermarck, Hubert

Chemosensitization of solid tumors by inhibition of Bcl-xL expression using DNAzyme

- Yu, Xiaohui, Yang, Lifang, Cairns, Murray J., Dass, Crispin, Saravolac, Edward, Li, Xiong, Sun, Lun-Quan

Histone deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1

- Shahbazi, Jeyran, Scarlett, Christopher J., Lock, Richard B., Liu, Tao, Norris, Murray D., Liu, Bing, Haber, Michelle, Tee, Andrew E., Carrier, Alice, Biankin, Aandrew V., London, Wendy B., Marshall, Glenn M.

Noxa upregulation by oncogenic activation of MEK/ERK through CREB promotes autophagy in human melanoma cells

- Liu, Yi Lun, Lai, Fritz, Jin, Lei, Zhang, Xu Dong, Wilmott, James S., Yan, Xu Guang, Liu, Xiao Ying, Luan, Qi, Guo, Su Tang, Jiang, Chen Chen, Tseng, Hsin-Yi, Scolyer, Richard A.