Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits
- Creator: Keaton, Jacob M. , Kamali, Zoha , Young, William J. , Lehtimäki, T , Raitakari, OT , Johnson, AD , Newton-Cheh, C , Brown, MJ , Dominiczak, AF , Sever, PJ , Poulter, N , Chambers, JC , Elosua, R , Traylor, Matthew , Siscovick, D , Esko, T , Metspalu, A , Strawbridge, RJ , Laakso, M , Hamsten, A , Hottenga, J-J , de Geus, E , Morris, AD , Palmer, CNA , Giri, Ayush , Nolte, IM , Milaneschi, Y , Marten, J , Wright, A , Zeggini, E , Howson, JMM , O'Donnell, CJ , Spector, T , Nalls, MA , Simonsick, EM , Zheng, Zhili , Liu, Y , van Duijn, CM , Butterworth, AS , Danesh, JN , Menni, C , Wareham, NJ , Khaw, K-T , Sun, YV , Wilson, PWF , Cho, K , Zeng, Jian , Visscher, PM , Denny, JC , Million Veteran Program, , Lifelines Cohort Study, , CHARGE consortium, , ICBP Consortium, , Levy, D , Edwards, TL , Munroe, PB , Snieder, H , Chasman, Daniel I. , Warren, HR , Morris, Andrew P. , Caulfield, Mark J. , Hwang, Shih-Jen , Kooner, Jaspal S. , Xie, Tian , Attia, John R. , Attia, JR , Morrison, AC , Loos, RJF , Kristiansson, K , Schmidt, R , Hicks, AA , Pramstaller, PP , Nelson, CP , Samani, NJ , Vaez, Ahmad , Risch, L , Gyllensten, U , Melander, O , Riese, H , Wilson, JF , Campbell, H , Rich, SS , Psaty, BM , Lu, Y , Rotter, JI , Williams, Ariel , Guo, X , Rice, KM , Vollenweider, P , Sundström, J , Langenberg, C , Tobin, MD , Giedraitis, V , Luan, J , Tuomilehto, J , Kutalik, Z , Goleva, Slavina B. , Ripatti, S , Salomaa, V , Girotto, G , Trompet, S , Jukema, JW , van der Harst, P , Ridker, PM , Giulianini, F , Vitart, V , Goel, A , Ani, Alireza , Watkins, H , Harris, SE , Deary, IJ , van der Most, PJ , Oldehinkel, AJ , Keavney, BD , Hayward, C , Campbell, A , Boehnke, M , Scott, LJ , Evangelou, Evangelos , Boutin, T , Mamasoula, C , Järvelin, M-R , Peters, A , Gieger, C , Lakatta, EG , Cucca, F , Hui, J , Knekt, P , Enroth, S , Hellwege, Jacklyn N. , De Borst, MH , Polašek, O , Concas, MP , Catamo, E , Cocca, M , Li-Gao, R , Hofer, E , Schmidt, H , Spedicati, B , Waldenberger, M , Yengo, Loic , Strachan, DP , Laan, M , Teumer, A , Dörr, M , Gudnason, V , Cook, JP , Ruggiero, D , Kolcic, I , Boerwinkle, E , Traglia, M
- Resource Type: journal article
- Date: 2024
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
- Creator: Kanoni, Stavroula , Graham, Sarah E. , Locke, Adam E. , Matteo, F , McDaid, AF , Marques-Vidal, P , Wielscher, M , Trompet, S , Sattar, N , Mollehave, LT , Munz, M , Zeng, L , Huang, J , Marouli, Eirini , Yang, B , Poveda, A , Kurbasic, A , Lamina, C , Forer, L , Scholz, M , Galesloot, TE , Bradfeld, JP , Ruotsalainen, SE , Daw, E , Zajac, Greg J. M. , Zmuda, JM , Mitchell, JS , Fuchsberger, C , Christensen, H , Brody, JA , Vazquez-Moreno, M , Feitosa, MF , Wojczynski, MK , Wang, Z , Preuss, MH , Wu, Kuan-Han H. , Mangino, M , Christofdou, P , Verweij, N , Benjamins, JW , Engmann, J , Tsao, NL , Verma, A , Slieker, RC , Lo, KS , Zilhao, NR , Ntalla, Ioanna , Le, P , Kleber, ME , Delgado, GE , Huo, S , Ikeda, DD , Iha, H , Yang, J , Liu, J , Leonard, HL , Marten, J , Hui, Qin , Frank, M , Schmidt, B , Smyth, LJ , Canadas-Garre, M , Wang, Carol A. , Nakatochi, M , Wong, A , Hutri-Kahonen, N , Sim, X , Xia, R , Klarin, Derek , Huerta-Chagoya, A , Fernandez-Lopez, JC , Lyssenko, V , Nongmaithem, SS , Bayyana, S , Stringham, HM , Irvin, MR , Oldmeadow, C , Kim, H-N , Ryu, S , Hilliard, Austin T. , Timmers, PRHJ , Arbeeva, L , Dorajoo, R , Lange, LA , Prasad, G , Lores-Motta, L , Pauper, M , Long, J , Li, X , Theusch, E , Wang, Zeyuan , Takeuchi, F , Spracklen, CN , Loukola, A , Bollepalli, S , Warner, SC , Wang, YX , Wei, WB , Nutile, T , Ruggiero, D , Sung, YJ , Xue, Chao , Chen, S , Liu, F , Kentistou, KA , Banas, B , Nardone, GG , Meidtner, K , Bielak, LF , Smith, JA , Hebbar, P , Wang, Yuxuan , Thorleifsson, Gudmar , Farmaki, A-E , Hofer, E , Lin, M , Concas, MP , Vaccargiu, S , van der Most, PJ , Pitkanen, N , Cade, BE , van der Laan, SW , Chitrala, KN , Helgadottir, A , Weiss, S , Bentley, AR , Doumatey, AP , Adeyemo, AA , Lee, JY , Petersen, ERB , Nielsen, AA , Choi, HS , Nethander, M , Freitag-Wolf, S , Gudbjartsson, DF , Southam, L , Rayner, NW , Wang, CA , Lin, S-Y , Wang, J-S , Couture, C , Lyytikainen, L-P , Nikus, K , Cuellar-Partida, G , Vestergaard, H , Holm, H , Hidalgo, B , Giannakopoulou, O , Cai, Q , Obura, MO , van Setten, J , Liang, J , Tang, H , Terzikhan, N , Shin, JH , Olafsson, I , Jackson, RD , Reiner, AP , Martin, LW , Chen, Z , Li, L , Kawaguchi, T , Thiery, J , Bis, JC , Launer, LJ , Li, H , Hwang, MY , Nalls, MA , Raitakari, OT , Ichihara, S , Wild, SH , Nelson, CP , Campbell, H , Jager, S , Nabika, T , Al-Mulla, F , Niinikoski, H , Han, S , Braund, PS , Kolcic, I , Kovacs, P , Giardoglou, T , Katsuya, T , de Kleijn, D , de Borst, GJ , Kim, EK , Adams, HHH , Ikram, MA , Akiyama, M , Zhu, X , Asselbergs, FW , Kraaijeveld, AO , Beulens, JWJ , Shu, X-O , Rallidis, LS , Pedersen, O , Hansen, T , Mitchell, P , Hewitt, AW , Sakaue, S , Kahonen, M , Perusse, L , Bouchard, C , Tonjes, A , Chen, Y-DI , Pennell, Craig E. , Mori, TA , Lieb, W , Franke, A , Ohlsson, C , Terao, C , Mellstrom, D , Cho, YS , Lee, H , Yuan, J-M , Koh, W-P , Rhee, SY , Woo, J-T , Heid, IM , Stark, KJ , Zimmermann, ME , Surakka, Ida , Kanai, M , Volzke, H , Homuth, G , Evans, MK , Zonderman, AB , Polasek, O , Pasterkamp, G , Hoefer, IE , Redline, S , Pahkala, K , Oldehinkel, AJ , Zhou, W , Snieder, H , Biino, G , Schmidt, R , Schmidt, H , Bandinelli, S , Dedoussis, G , Thanaraj, TA , Kardia, SLR , Peyser, PA , Kato, N , Brumpton, BM , Schulze, MB , Girotto, G , Boger, CA , Jung, B , Joshi, PK , Bennett, DA , De Jager, PL , Lu, X , Mamakou, V , Brown, M , Rasheed, H , Caulfeld, MJ , Munroe, PB , Guo, X , Ciullo, M , Jonas, JB , Samani, NJ , Kaprio, J , Pajukanta, P , Tusie-Luna, T , Aguilar-Salinas, CA , Havulinna, AS , Adair, LS , Bechayda, SA , de Silva, HJ , Wickremasinghe, AR , Krauss, RM , Wu, J-Y , Zheng, W , Hollander, AI , Bharadwaj, D , Correa, A , Veturi, Y , Wilson, JG , Lind, L , Heng, C-K , Nelson, AE , Golightly, YM , Wilson, JF , Penninx, B , Kim, H-L , Attia, John , Scott, RJ , Pacheco, JA , Rao, DC , Arnett, DK , Hunt, SC , Walker, M , Koistinen, HA , Chandak, GR , Mercader, JM , Costanzo, MC , Jang, D , Burtt, NP , Rosenthal, EA , Villalpando, CG , Orozco, L , Fornage, M , Tai, E , van Dam, RM , Lehtimaki, T , Chaturvedi, N , Yokota, M , Reilly, DF , Lingren, T , McKnight, AJ , Kee, F , Jockel, K-H , McCarthy, M , Palmer, CNA , Vitart, V , Hayward, C , Simonsick, E , van Duijn, CM , Jin, Z-B , Feng, Q , Qu, J , Hishigaki, H , Lin, X , Marz, W , Gudnason, V , Tardif, J-C , Lettre, G , t Hart, LM , Elders, PJM , Damrauer, SM , Ramdas, Shweta , Kullo, IJ , Kumari, M , Kivimaki, M , van der Harst, P , Spector, TD , Loos, RJF , Province, MA , Parra, EJ , Cruz, M , Psaty, BM , Brandslund, I , Narita, A , Pramstaller, PP , Rotimi, CN , Christensen, K , Ripatti, S , Widen, E , Hakonarson, H , Grant, SFA , Kiemeney, LALM , de Graaf, J , Loefer, M , Takayama, J , Kronenberg, F , Gu, D , Erdmann, J , Schunkert, H , Franks, PW , Linneberg, A , Jukema, JW , Khera, A , Mannikko, M , Jarvelin, M-R , Martin, HC , Kutalik, Z , Francesco, C , Mook-Kanamori, DO , van Dijk, KW , Watkins, H , Strachan, DP , Grarup, N , Sever, P , Poulter, N , Chuang, L-M , Hunt, KA , Rotter, J , Dantoft, TM , Karpe, F , Neville, MJ , Timpson, NJ , Cheng, C-Y , Wong, T-Y , Khor, CC , Sabanayagam, C , Trivedi, B , Peters, A , Gieger, C , Hattersley, AT , Pedersen, NL , Magnusson, PKE , Boomsma, D , Willemsen, AHM , Cupples, L , van Meurs, JBJ , Ghanbari, M , Haessler, J , Gordon-Larsen, P , Huang, W , Kim, YJ , Tabara, Y , Wareham, NJ , Langenberg, C , Zeggini, E , Kuusisto, J , Laakso, M , Ingelsson, E , Giulianini, F , Abecasis, G , Chambers, JC , Kooner, JS , de Vries, PS , Morrison, AC , Hazelhurst, S , Ramsay, M , North, KE , Daviglus, M , Kraft, P , Bradford, Y , Martin, NG , Whitfeld, JB , Abbas, S , Saleheen, D , Walters, RG , Holmes, M , Black, C , Smith, BH , Baras, A , Justice, AE , Miller, JE , Buring, JE , Ridker, PM , Chasman, D , Kooperberg, C , Tamiya, G , Yamamoto, M , van Heel, DA , Trembath, RC , Wei, W-Q , Jarvik, GP , Zhu, Xiang , Campbell, A , Namjou, B , Hayes, MG , Ritchie, MD , Jousilahti, P , Salomaa, V , Hveem, K , Asvold, BO , Kubo, M , Kamatani, Y , Okada, Y , Lin, K , Murakami, Y , Kim, B-J , Thorsteinsdottir, U , Stefansson, K , Zhang, J , Chen, YE , Ho, Y-L , Lynch, JA , Rader, DJ , Tsao, PS , Millwood, IY , Chang, K-M , Cho, K , O'Donnell, CJ , Gaziano, JM , Wilson, PWF , Frayling, TM , Hirschhorn, JN , Kathiresan, S , Mohlke, KL , Sun, Y , Rasheed, A , Morris, AP , Boehnke, M , Brown, CD , Natarajan, P , Deloukas, P , Willer, CJ , Assimes, TL , Peloso, GM , Demirkan, A , Hindy, G , Faul, JD , Zhao, W , Weir, DR , Turman, C , Huang, H , Clarke, Shoa L. , Graf, M , Choudhury, A , Sengupta, D , Mahajan, A , Brown, MR , Zhang, W , Yu, K , Schmidt, EM , Pandit, A , Gustafsson, S , Bhatti, Konain Fatima , Yin, X , Luan, J , Zhao, J-H , Matsuda, F , Jang, H-M , Yoon, K , Medina-Gomez, C , Pitsillides, A , Hottenga, JJ , Wood, AR , Vedantam, Sailaja , Ji, Y , Gao, Z , Haworth, S , Yousri, NA , Mitchell, RE , Chai, JF , Aadahl, M , Bjerregaard, AA , Yao, J , Manichaikul, A , Winkler, Thomas W. , Hwu, C-M , Hung, Y-J , Warren, HR , Ramirez, J , Bork-Jensen, J , Karhus, LL , Goel, A , Sabater-Lleal, M , Noordam, R , Mauro, P
- Resource Type: journal article
- Date: 2022
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals
- Creator: Giri, Ayush , Hellwege, Jacklyn N. , Keaton, Jacob M. , Park, Jihwan , Qiu, Chengxiang , Warren, Helen R. , Torstenson, Eric S. , Kovesdy, Csaba P. , Sun, Yan V. , Wilson, Otis D. , Robinson-Cohen, Cassianne , Roumie, Christianne L. , Chung, Cecilia P. , Birdwell, Kelly A. , Damrauer, Scott M. , DuVall, Scott L. , Klarin, Derek , Cho, Kelly , Wang, Yu , Evangelou, Evangelos , Attia, John , Oldmeadow, Christopher , Wei, WQ , Jarvelin, MR , Hennig, BJ , Timpson, NJ , Smith, JC , Xu, Y , Matheny, ME , Siew, EE , Lindgren, C , Herzig, KH , Dedoussis, G , Denny, JC , Psaty, BM , Howson, JMM , Munroe, PB , Newton-Cheh, C , Caulfield, MJ , Elliott, P , Gaziano, JM , Concato, J , Wilson, PWF , Tsao, PS , Velez Edwards, DR , Susztak, K , O¿Donnell, CJ , Hung, AM , Edwards, TL , Cabrera, Claudia P. , Wain, LV , Shrestha, R , Mautz, BS , Akwo, EA , Sargurupremraj, M , Debette, S , Boehnke, M , Scott, LJ , Luan, J , Zhao, JH , Willems, SM , Thériault, S , Shah, N , Almgren, P , Li-Gao, R , Verweij, N , Boutin, TS , Mangino, M , Ntalla, I , Feofanova, E , Surendran, P , Cook, JP , Karthikeyan, S , Lahrouchi, N , Liu, C , Sepúlveda, N , Richardson, TG , Kraja, A , Amouyel, P , Farrall, M , Poulter, NR , Laakso, M , Zeggini, E , Sever, P , Scott, RA , Langenberg, C , Wareham, NJ , Conen, D , Palmer, CNA , Chasman, DI , Ridker, PM , Melander, O , Mook-Kanamori, DO , van der Harst, P , Cucca, F , Schlessinger, D , Hayward, C , Spector, TD
- Resource Type: journal article
- Date: 2019