A road map for the treatment of pediatric diffuse midline glioma
- Creator: Koschmann, Carl , Al-Holou, Wajd N. , Clausen, Madison , Dang, Derek , Doherty, Robert , Duchatel, Ryan , Dun, Matthew , Filbin, Mariella , Franson, Andrea , Galban, Stefanie , Garcia Moure, Marc , Garton, Hugh , Alonso, Marta M. , Gowda, Pruthvi , Marques, JG , Hawkins, C , Heath, A , Hulleman, E , Ji, S , Jones, C , Kilburn, L , Kline, C , Koldobskiy, MA , Anastas, Jamie , Lim, D , Lowenstein, PR , Lu, QR , Lum, J , Mack, S , Magge, S , Marini, B , Martin, D , Marupudi, N , Messinger, D , Bandopadhayay, Pratiti , Mody, R , Morgan, M , Mota, M , Muraszko, K , Mueller, S , Natarajan, SK , Nazarian, J , Niculcea, M , Nuechterlein, N , Okada, H , Barron, Tara , Opipari, V , Pai, MP , Pal, S , Peterson, E , Phoenix, T , Prensner, JR , Pun, M , Raju, GP , Reitman, ZJ , Resnick, A , Becher, Oren , Rogawski, D , Saratsis, A , Sbergio, SG , Souweidane, M , Stafford, JM , Tzaridis, T , Venkataraman, S , Vittorio, O , Wadden, J , Wahl, D , Cartaxo, Rodrigo , Wechsler-Reya, RJ , Yadav, VN , Zhang, X , Zhang, Q , Venneti, S , Castro, Maria G. , Chung, Chan
- Resource Type: journal article
- Date: 2024
PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma
- Creator: Duchatel, Ryan J. , Jackson, Evangeline R. , Kearney, Padraic S. , Jamaluddin, M. Fairuz B. , Douglas, Alicia M. , Beitaki, Tyrone , McEwen, Holly P. , Persson, Mika L. , Hocke, Emily A. , Jain, Vaibhav , Aksu, Michael , Manning, Elizabeth E. , Parackal, Sarah G. , Murray, Heather C. , Verrills, Nicole M. , Hua, Susan , Cairns, Murray J. , Alvaro, Frank , Dayas, Christopher V. , Dun, Matthew D. , Hua, S , de Bock, CE , Colino-Sanguino, Y , Kiltschewskij, Dylan , Valdes-Mora, F , Tsoli, M , Ziegler, DS , Cairns, MJ , Raabe, EH , Vitanza, NA , Hulleman, E , Phoenix, TN , Koschmann, C , Alvaro, F , Findlay, Izac J. , Dayas, CV , Tinkle, CL , Wheeler, H , Whittle, JR , Eisenstat, DD , Firestein, R , Mueller, S , Valvi, S , Hansford, JR , Ashley, DM , Mannan, Abdul , Gregory, SG , Kilburn, LB , Nazarian, J , Cain, JE , Dun, MD , Staudt, Dilana E. , Thomas, Bryce C. , Germon, Zacary P. , Laternser, Sandra
- Resource Type: journal article
- Date: 2024
Clinical efficacy of ONC201 in H3K27M-mutant diffuse midline gliomas is driven by disruption of integrated metabolic and epigenetic pathways
- Creator: Venneti, Sriram , Kawakibi, Abed Rahman , Ramage, Samuel , Chi, Andrew , Wen, Patrick Y. , Arrillaga-Romany, Isabel , Batchelor, Tracy T. , Butowski, Nicholas A. , Sumrall, Ashley , Shonka, Nicole , Harrison, Rebecca A. , de Groot, John , Ji, Sunjong , Mehta, M , Hall, MD , Daghistani, D , Cloughesy, TF , Ellingson, BM , Beccaria, K , Varlet, P , Kim, MM , Umemura, Y , Garton, H , Waszak, Sebastian M. , Franson, A , Schwartz, J , Jain, R , Kachman, M , Baum, H , Burant, CF , Mottl, SL , Cartaxo, RT , John, V , Messinger, D , Sweha, StefanR , Qin, T , Peterson, E , Sajjakulnukit, P , Ravi, K , Waugh, A , Walling, D , Ding, Y , Xia, Z , Schwendeman, A , Hawes, D , Mota, Mateus , Yang, F , Judkins, AR , Wahl, D , Lyssiotis, CA , de la Nava, D , Alonso, MM , Eze, A , Spitzer, J , Schmidt, SV , Duchatel, Ryan J. , Pun, Matthew , Dun, Matthew D. , Cain, JE , Jiang, L , Stopka, SA , Baquer, G , Regan, MS , Filbin, MG , Agar, NYR , Zhao, L , Kumar-Sinha, C , Deogharkar, Akash , Mody, R , Chinnaiyan, A , Kurokawa, R , Pratt, D , Yadav, VN , Grill, J , Kline, C , Mueller, S , Resnick, A , Nazarian, J , Chung, Chan , Allen, JE , Odia, Y , Gardner, SL , Koschmann, C , Tarapore, Rohinton S.
- Resource Type: journal article
- Date: 2023
ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma
- Creator: Jackson, Evangeline R. , Duchatel, Ryan J. , Le Grand, Marion , Kearney, Padraic S. , Douglas, Alicia M. , Findlay, Izac J. , Germon, Zacary P. , McEwen, Holly P. , Beitaki, Tyrone S. , Patabendige, Adjanie , Skerrett-Byrne, David A. , Nixon, Brett , Staudt, Dilana E. , Smith, Nathan D. , Day, B , Manoharan, N , Nagabushan, S , Hansford, JR , Govender, D , McCowage, GB , Firestein, R , Howlett, M , Endersby, R , Persson, Mika L. , Gottardo, NG , Alvaro, F , Waszak, SM , Larsen, MR , Colino-Sanguino, Y , Valdés-Mora, F , Rakotomalala, A , Meignan, S , Pasquier, E , Andre, N , Mannan, Abdul , Hulleman, E , Eisenstat, DD , Vitanza, NA , Nazarian, J , Koschmann, C , Mueller, S , Cain, JE , Dun, MD , Yadavilli, Sridevi , Parackal, Sarah , Game, Shaye , Chong, Wai Chin , Jayasekara, W. Samantha N.
- Resource Type: journal article
- Date: 2023
Imipridones affect tumor bioenergetics and promote cell lineage differentiation in diffuse midline gliomas
- Creator: Przystal, Justyna M. , Cosentino, Chiara Cianciolo , Biery, Matt C. , Myers, Carrie , Olson, James M. , Panditharatna, Eshini , Kritzer, Bettina , Mourabit, Sulayaman , Vitanza, Nicholas A. , Filbin, Mariella G. , de Iuliis, Geoffry N. , Dun, Matthew D. , Yadavilli, Sridevi , Koschmann, C , Cain, JE , Grotzer, MA , Waszak, SM , Mueller, S , Nazarian, J , Zhang, Jie , Laternser, Sandra , Bonner, Erin R. , Prasad, Rachna , Dawood, Adam A. , Lobeto, Nina , Chong, Wai Chin
- Resource Type: journal article
- Date: 2022