Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
- Creator: Mullins, Niamh , Forstner, Andeas J. , Charney, Alexander W. , Kamatani, Y , Kennedy, JL , Kittel-Schneider, S , Knowles, JA , Kogevinas, M , Koromina, M , Kranz, TM , Kranzler, HR , Kubo, M , Kupka, R , Drange, Ole Kristian , Kushner, SA , Lavebratt, C , Lawrence, J , Leber, M , Lee, H-J , Lee, PH , Levy, SE , Lewis, C , Liao, C , Lucae, S , Gandal, Michael J. , Lundberg, M , MacIntyre, DJ , Maier, W , Maihofer, A , Malaspina, D , Maratou, E , Martinsson, L , Mattheisen, M , McCarroll, SA , McGregor, NW , Hagenaars, Saskia P. , McGuffin, P , McKay, JD , Medeiros, H , Medland, SE , Millischer, V , Montgomery, GW , Moran, JL , Morris, DW , Muhleisen, TW , O'Brien, N , Ikeda, Masashi , O'Donovan, C , Loohuis, LMO , Oruc, L , Papiol, S , Pardinas, AF , Perry, A , Pfennig, A , Porichi, E , Potash, JB , Quested, D , Kamitaki, Nolan , Raj, T , Rapaport, MH , DePaulo, JR , Regeer, EJ , Rice, JP , Rivas, F , Rivera, M , Roth, J , Roussos, P , Ruderfer, DM , Kim, Minsoo , Sanchez-Mora, C , Schulte, EC , Senner, F , Sharp, S , Shilling, PD , Sigurdsson, E , Sirignano, L , Slaney, C , Smeland, OB , Sobell, JL , Krebs, Kristi , Hansen, CS , Artigas, MS , Spijker, AT , Stein, DJ , Strauss, JS , Swiatkowska, B , Terao, C , Thorgeirsson, TE , Toma, C , Tooney, Paul , Panagiotaropoulou, Georgia , Tsermpini, E-E , Vawter, MP , Vedder, H , Walters, JTR , Witt, SH , Xi, S , Xu, W , Yang, JMK , Young, AH , Young, H , Schilder, Brian M. , Zandi, PP , Zhou, H , Zillich, L , Adolfsson, R , Agartz, I , Alda, M , Alfredsson, L , Babadjanova, G , Backlund, L , Baune, BT , O'Connell, Kevin S. , Sloofman, Laura G. , Bellivier, F , Bengesser, S , Berrettini, WH , Blackwood, DHR , Boehnke, M , Borglum, AD , Breen, G , Carr, VJ , Catts, S , Corvin, A , Steinberg, S , Craddock, N , Dannlowski, U , Dikeos, D , Esko, T , Etain, B , Ferentinos, P , Frye, M , Fullerton, JM , Gawlik, M , Gershon, ES , Trubetskoy, V , Goes, F , Green, MJ , Grigoroiu-Serbanescu, M , Hauser, J , Henskens, F , Hillert, J , Hong, KS , Hougaard, DM , Hultman, CM , Hveem, K , Winsvold, BS , Iwata, N , Jablensky, A , Jones, I , Jones, LA , Kahn, RS , Kelsoe, JR , Kirov, G , Landen, M , Leboyer, M , Lewis, CM , Won, H-H , Li, QS , Lissowska, J , Lochner, C , Loughland, Carmel , Martin, NG , Mathews, CA , Mayoral, F , McElroy, SL , McIntosh, AM , McMahon, FJ , Abramova, L , Melle, I , Michie, P , Milani, L , Mitchell, PB , Morken, G , Mors, O , Mortensen, PB , Mowry, B , Muller-Myhsok, B , Myers, RM , Adorjan, K , Neale, BM , Nievergelt, CM , Nordentoft, M , Nothen, MM , ODonovan, MC , Oedegaard, KJ , Olsson, T , Owen, MJ , Paciga, SA , Pantelis, C , Agerbo, E , Pato, C , Pato, MT , Patrinos, GP , Perlis, RH , Posthuma, D , Ramos-Quiroga, JA , Reif, A , Reininghaus, EZ , Ribases, M , Rietschel, M , Al Eissa, M , Ripke, S , Rouleau, GA , Saito, T , Schall, U , Schalling, M , Schofield, PR , Schulze, TG , Scott, LJ , Scott, RJ , Serretti, A , Albani, D , Weickert, CS , Smoller, JW , Stefansson, H , Stefansson, K , Stordal, E , Streit, F , Sullivan, PF , Turecki, G , Vaaler, AE , Vieta, E , Coombes, Brandon , Alliey-Rodriguez, N , Vincent, JB , Waldman, ID , Weickert, TW , Werge, T , Wray, NR , Zwart, J , Biernacka, JM , Nurnberger, J , Cichon, S , Edenberg, HJ , Anjorin, A , Stahl, EA , McQuillin, A , Di Florio, A , Ophoff, RA , Andreassen, OA , Antilla, V , Antoniou, A , Awasthi, S , Baek, JH , Baekvad-Hansen, M , Bass, N , Bauer, M , Beins, EC , Coleman, Jonathan R. I. , Bergen, SE , Birner, A , Pedersen, CB , Boen, E , Boks, MP , Bosch, R , Brum, M , Brumpton, BM , Brunkhorst-Kanaan, N , Budde, M , Qiao, Zhen , Bybjerg-Grauholm, J , Byerley, W , Cairns, Murray , Casas, M , Cervantes, P , Clarke, T-K , Cruceanu, C , Cuellar-Barboza, A , Cunningham, J , Curtis, D , Als, Thomas D. , Czerski, PM , Dale, AM , Dalkner, N , David, FS , Degenhardt, F , Djurovic, S , Dobbyn, AL , Douzenis, A , Elvsashagen, T , Escott-Price, V , Bigdeli, Tim B. , Ferrier, IN , Fiorentino, A , Foroud, TM , Forty, L , Frank, J , Frei, O , Freimer, NB , Frisen, L , Gade, K , Garnham, J , Børte, Sigrid , Gelernter, J , Pedersen, MG , Gizer, IR , Gordon, SD , Gordon-Smith, K , Greenwood, TA , Grove, J , Guzman-Parra, J , Ha, K , Haraldsson, M , Bryois, Julien , Hautzinger, M , Heilbronner, U , Hellgren, D , Herms, S , Hoffmann, P , Holmans, PA , Huckins, L , Jamain, S , Johnson, JS , Kalman, JL
- Resource Type: journal article
- Date: 2021
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation
- Creator: Min, Josine L. , Hemani, Gibran , Bretherick, Andrew D. , Pennell, Craig E. , Richardson, Tom G. , Klughammer, Johanna , Iotchkova, Valentina , Sharp, Gemma , Al Khleifat, Ahmad , Shatunov, Aleksey , Iacoangeli, Alfredo , McArdle, Wendy L. , Ho, Karen M. , Hannon, Ellis , Kumar, Ashish , Söderhäll, C , Soriano-Tárraga, C , Giralt-Steinhauer, E , Kazmi, N , Mason, D , McRae, AF , Corcoran, DL , Sugden, K , Kasela, S , Dekkers, Koen F. , Cardona, A , Day, FR , Cugliari, G , Viberti, C , Guarrera, S , Lerro, M , Gupta, R , Bollepalli, S , Mandaviya, P , Zeng, Y , Castillo-Fernandez, Juan , Clarke, TK , Walker, RM , Schmoll, V , Czamara, D , Ruiz-Arenas, C , Rezwan, FI , Marioni, RE , Lin, T , Awaloff, Y , Germain, M , Luijk, Rene , Aïssi, D , Zwamborn, R , van Eijk, K , Dekker, A , van Dongen, J , Hottenga, JJ , Willemsen, G , Xu, CJ , Barturen, G , Català-Moll, F , Carnero-Montoro, Elena , Kerick, M , Wang, Carol , Melton, P , Elliott, HR , Shin, J , Bernard, M , Yet, I , Smart, M , Gorrie-Stone, T , Shaw, C , Lawson, Daniel J. , Al Chalabi, A , Ring, SM , Pershagen, G , Melén, E , Jiménez-Conde, J , Roquer, J , Lawlor, DA , Wright, J , Martin, NG , Montgomery, GW , Burrows, Kimberley , Moffitt, TE , Poulton, R , Esko, T , Milani, L , Metspalu, A , Perry, JRB , Ong, KK , Wareham, NJ , Matullo, G , Sacerdote, C , Suderman, Matthew , Panico, S , Caspi, A , Arseneault, L , Gagnon, F , Ollikainen, M , Kaprio, J , Felix, JF , Rivadeneira, F , Tiemeier, H , van IJzendoorn, MH
- Resource Type: journal article
- Date: 2021
Associations of autozygosity with a broad range of human phenotypes
- Creator: Clark, David W. , Cocca, M , Collins, FS , Concas, MP , Corley, J , Cugliari, G , Van Dam, RM , Damulina, A , Daneshpour, MS , Day, FR , Delgado, GE , Dhana, K , Doney, ASF , Doerr, M , Doumatey, AP , Dzimiri, N , Ebenesersdottir, SS , Elliott, J , Elliott, P , Ewert, R , Felix, JF , Fischer, K , Freedman, BI , Girotto, G , Goel, A , Gogele, M , Goodarzi, MO , Graff, M , Granot-Hershkovitz, E , Grodstein, F , Guarrera, S , Gudbjartsson, DF , Guity, K , Gunnarsson, B , Guo, Y , Hagenaars, SP , Haiman, CA , Halevy, A , Harris, TB , Hedayati, M , van Heel, DA , Hirata, M , Hofer, I , Hsiung, CA , Huang, J , Hung, Y-J , Ikram, MA , Jagadeesan, A , Jousilahti, P , Kamatani, Y , Kanai, M , Kerrison, ND , Kessler, T , Khaw, K-T , Khor, CC , de Kleijn, DPV , Koh, W-P , Kolcic, I , Kraft, P , Kramer, BK , Kutalik, Z , Kuusisto, J , Langenberg, C , Launer, LJ , Lawlor, DA , Lee, I-T , Lee, W-J , Lerch, MM , Li, L , Liu, J , Loh, M , London, SJ , Loomis, S , Lu, Y , Luan, J , Magi, R , Manichaikul, AW , Manunta, P , Masson, G , Matoba, N , Mei, XW , Meisinger, C , Meitinger, T , Mezzavilla, M , Milani, L , Millwood, IY , Momozawa, Y , Moore, A , Morange, P-E , Moreno-Macias, H , Mori, TA , Morrison, AC , Muka, T , Murakami, Y , Murray, AD , de Mutsert, R , Mychaleckyj, JC , Nalls, MA , Nauck, M , Neville, MJ , Nolte, IM , Ong, KK , Orozco, L , Padmanabhan, S , Palsson, G , Pankow, JS , Pattaro, C , Pattie, A , Polasek, O , Poulter, N , Pramstaller, PP , Quintana-Murci, L , Raikkonen, K , Ralhan, S , Rao, DC , van Rheenen, W , Rich, SS , Ridker, PM , Rietveld, CA , Robino, A , van Rooij, FJA , Ruggiero, D , Saba, Y , Sabanayagam, C , Sabater-Lleal, M , Felicita Sala, C , Salomaa, V , Sandow, K , Schmidt, H , Scott, LJ , Scott, WR , Sedaghati-Khayat, B , Sennblad, B , van Setten, J , Sever, PJ , Sheu, WH-H , Shi, Y , Shrestha, S , Shukla, SR , Sigurdsson, JK , Sikka, TT , Singh, JR , Smith, BH , Stancakova, A , Stanton, A , Starr, JM , Stefansdottir, L , Straker, L , Sulem, P , Sveinbjornsson, G , Swertz, MA , Taylor, AM , Taylor, KD , Terzikhan, N , Tham, Y-C , Thorleifsson, G , Thorsteinsdottir, U , Tillander, A , Tracy, RP , Tusie-Luna, T , Tzoulaki, I , Vaccargiu, S , Vangipurapu, J , Veldink, JH , Vitart, V , Volker, U , Vuoksimaa, E , Wakil, SM , Waldenberger, M , Wander, GS , Wang, YX , Wareham, NJ , Wild, S , Yajnik, CS , Yuan, J-M , Zeng, L , Zhang, L , Zhou, J , Amin, N , Asselbergs, FW , Bakker, SJL , Becker, DM , Lehne, B , Bennett, DA , van den Berg, LH , Berndt, SI , Bharadwaj, D , Bielak, LF , Bochud, M , Boehnke, M , Bouchard, C , Bradfield, JP , Brody, JA , Campbell, A , Carmi, S , Caulfield, MJ , Cesarini, D , Chambers, JC , Chandak, GR , Cheng, C-Y , Ciullo, M , Cornelis, M , Cusi, D , Smith, GD , Deary, IJ , Dorajoo, R , van Duijn, CM , Ellinghaus, D , Erdmann, J , Eriksson, JG , Evangelou, E , Evans, MK , Faul, JD , Feenstra, B , Feitosa, M , Foisy, S , Franke, A , Friedlander, Y , Gasparini, P , Gieger, C , Gonzalez, C , Goyette, P , Grant, SFA , Griffiths, LR , Groop, L , Gudnason, V , Gyllensten, U , Hakonarson, H , Hamsten, A , van der Harst, P , Heng, C-K , Hicks, AA , Hochner, H , Huikuri, H , Hunt, SC , Jaddoe, VWV , De Jager, PL , Johannesson, M , Johansson, A , Jonas, JB , Jukema, JW , Junttila, J , Kaprio, J , Kardia, SLR , Karpe, F , Kumari, M , Laakso, M , van der Laan, SW , Lahti, J , Laudes, M , Lea, RA , Lieb, W , Lumley, T , Martin, NG , Marz, W , Matullo, G , McCarthy, MI , Medland, SE , Merriman, TR , Metspalu, A , Meyer, BF , Mohlke, KL , Montgomery, GW , Mook-Kanamori, D , Munroe, PB , North, KE , Nyholt, DR , O'connell, JR , Ober, C , Oldehinkel, AJ , Palmas, W , Palmer, C , Pasterkamp, GG , Patin, E , Pennell, CE , Perusse, L , Peyser, PA , Pirastu, M , Polderman, TJC , Porteous, DJ , Posthuma, D , Psaty, BM , Rioux, JD , Rivadeneira, F , Rotimi, C , Rotter, JI , Rudan, I , Den Ruijter, HM , Sanghera, DK , Sattar, N , Schmidt, R , Schulze, MB , Schunkert, H , Scott, RA , Shuldiner, AR , Sim, X , Small, N , Smith, JA , Sotoodehnia, N , Tai, E-S , Teumer, A , Timpson, NJ , Toniolo, D , Tregouet, D-A , Tuomi, T , Vollenweider, P , Wang, CA , Weir, DR , Whitfield, JB , Wijmenga, C , Wong, T-Y , Wright, J , Yang, J , Yu, L , Zemel, BS , Zonderman, AB , Perola, M , Magnusson, PKE , Uitterlinden, AG , Kooner, JS , Chasman, DI , Loos, RJF , Franceschini, N , Franke, L , Haley, CS , Hayward, C , Walters, RG , Perry, JRB , Esko, T , Helgason, A , Stefansson, K , Joshi, PK , Kubo, M , Wilson, JF , Okada, Yukinori , Deelen, Patrick , Wang, Carol A. , Pennell, Craig E. , Orozco, Lorena , Rohde, Rebecca , Schurmann, Claudia , Guo, Xiuqing , Giulianini, Franco , Zhang, Weihua , Medina-Gomez, Carolina , Karlsson, Robert , Bao, Yanchun , Bartz, Traci M. , Moore, Kristjan H. S. , Baumbach, Clemens , Biino, G , Bixley, MJ , Brumat, M , Chai, J-F , Corre, T , Cousminer, DL , Dekker, AM , Eccles, DA , Van Eijk, KR , Mason, Dan , Fuchsberger, C , Gao, H , Germain, M , Gordon, SD , de Haan, HG , Harris, SE , Hofer, E , Huerta-Chagoya, A , Igartua, C , Jansen, IE , Pirastu, Nicola , Jia, Y , Kacprowski, T , Karlsson, T , Kleber, ME , Li, SA , Li-Gao, R , Mahajan, A , Matsuda, K , Meidtner, K , Meng, W , Gandin, Ilaria , Montasser, ME , van der Most, PJ , Munz, M , Nutile, T , Palviainen, T , Prasad, G , Prasad, RB , Priyanka, TDS , Rizzi, F , Salvi, E , Mattsson, Hannele , Sapkota, BR , Shriner, D , Skotte, L , Smart, MC , Smith, AV , van der Spek, A , Spracklen, CN , Strawbridge, RJ , Tajuddin, SM , Trompet, S , Barnes, Catriona L. K. , Turman, C , Verweij, N , Viberti, C , Wang, L , Warren, HR , Wootton, RE , Yanek, LR , Yao, J , Yousri, NA , Zhao, W , Lin, Kuang , Adeyemo, AA , Afaq, S , Alberto Aguilar-Salinas, C , Akiyama, M , Albert, ML , Allison, MA , Alver, M , Aung, T , Azizi, F , Bentley, AR , Zhao, Jing Hua , Boeing, H , Boerwinkle, E , Borja, JB , de Borst, GJ , Bottinger, EP , Broer, L , Campbell, H , Chanock, S , Chee, M-L , Chen, G
- Resource Type: journal article
- Date: 2019
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
- Creator: Karlsson Linnér, Richard , Kalnapenkis, A , Kasela, S , Kettunen, J , Kim, Y , Kirsten, H , Kovacs, P , Krohn, K , Kronberg-Guzman, J , Kukushkina, V , Kutalik, Z , Lee, B , Lehtimäki, T , Loeffler, M , Marigorta, UM , Metspalu, A , Milani, L , Montgomery, GW , Müller-Nurasyid, M , Nauck, M , Penninx, B , Perola, M , Biroli, Poetro , Nivard, Michel G. , Okbay, Aysu , Rietveld, Cornelius A. , Timshel, Pascal N. , Trzaskowski, Maciej , de Vlaming, Ronald , Zünd, Christian L. , Bao, Yanchun , Buzdugan, Laura , Caplin, Ann H. , Kong, Edward , Chen, Chia-Yen , Eibich, P , Fontanillas, P , Gonzalez, JR , Joshi, PK , Karhunen, V , Kleinman, A , Levin, RZ , Lill, CM , Meddens, GA , Meddens, S. Fleur W. , Muntané, G , Sanchez-Roige, S , Rooij, FJV , Taskesen, E , Wu, Y , Zhang, F , Agee, M , Alipanahi, B , Bell, RK , Bryc, K , Wedow, Robbee , Elson, SL , Furlotte, NA , Huber, KE , Litterman, NK , McCreight, JC , McIntyre, MH , Mountain, JL , Northover, CAM , Pitts, SJ , Sathirapongsasuti, JF , Fontana, Mark Alan , Sazonova, OV , Shelton, JF , Shringarpure, S , Tian, C , Tung, JY , Vacic, V , Wilson, CH , Agbessi, M , Ahsan, H , Alves, I , Lebreton, Maël , Andiappan, A , Awadalla, P , Battle, A , Beutner, F , Jan Bonder, M , Boomsma, DI , Christiansen, M , Claringbould, A , Deelen, P , Esko, T , Tino, Stephen P. , Favé, MJ , Franke, L , Frayling, T , Gharib, SA , Gibson, G , Oldmeadow, Christopher , Holliday, Elizabeth G. , Scott, Rodney J. , Attia, John R. , Abdellaoui, Abdel , Hammerschlag, Anke R.
- Resource Type: journal article
- Date: 2019
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
- Creator: Evangelou, Evangelos , Warren, Helen R. , Ng, Fu Liang , Evangelou, Marina , Witkowska, Katarzyna , Tzanis, Evan , Hellwege, Jacklyn N. , Giri, Ayush , Velez Edwards, Digna R. , Sun, Yan V. , Cho, Kelly , Gaziano, J. Michael , Mosen-Ansorena, David , Wilson, Peter W. F. , Tsao, PS , Kovesdy, CP , Esko, T , Mägi, R , Milani, L , Almgren, P , Boutin, T , Debette, S , Ding, J , Mifsud, Borbala , Giulianini, F , Holliday, Elizabeth G. , Jackson, AU , Li-Gao, R , Lin, WY , Luan, J , Mangino, M , Oldmeadow, Christopher , Attia, John R. , Qian, Y , Pazoki, Raha , Sargurupremraj, M , Shah, N , Surendran, P , Thériault, S , Verweij, N , Willems, SM , Zhao, JH , Amouyel, P , Connell, J , de Mutsert, R , Gao, He , Doney, ASF , Farrall, M , Menni, C , Morris, AD , Noordam, R , Paré, G , Poulter, NR , Shields, DC , Stanton, A , Thom, S , Ntritsos, Georgios , Abecasis, G , Amin, N , Arking, DE , Ayers, KL , Barbieri, CM , Batini, C , Bis, JC , Blake, T , Bochud, M , Boehnke, M , Dimou, Niki , Boerwinkle, E , Boomsma, DI , Bottinger, EP , Braund, PS , Brumat, M , Campbell, A , Campbell, H , Chakravarti, A , Chambers, JC , Cabrera, Claudia P. , Karaman, Ibrahim
- Resource Type: journal article
- Date: 2018