A Multi-Layer Functional Genomic Analysis to Understand Noncoding Genetic Variation in Lipids
- Creator: Ramdas, Shweta , Judd, Jonathan , Bhatti, Konain Fatima , Noordam, R , Mauro, P , Matteo, F , McDaid, AF , Marques-Vidal, P , Wielscher, M , Trompet, S , Sattar, N , Mollehave, LT , Munz, M , Vedantam, Sailaja , Zeng, L , Huang, J , Yang, B , Poveda, A , Kurbasic, A , Schonherr, S , Forer, L , Scholz, M , Galesloot, TE , Bradfield, JP , Winkler, Thomas W. , Ruotsalainen, SE , Daw, EW , Zmuda, JM , Mitchell, JS , Fuchsberger, C , Christensen, H , Brody, JA , Le, P , Feitosa, MF , Wojczynski, MK , Locke, Adam E. , Hemerich, D , Preuss, M , Mangino, M , Christofidou, P , Verweij, N , Benjamins, JW , Engmann, J , Noah, TL , Verma, A , Slieker, RC , Marouli, Eirini , Lo, KS , Zilhao, NR , Kleber, ME , Delgado, GE , Huo, S , Ikeda, DD , Iha, H , Yang, J , Liu, J , Demirkan, A , Zajac, Greg J. M. , Leonard, HL , Marten, J , Emmel, C , Schmidt, B , Smyth, LJ , Canadas-Garre, M , Wang, C , Nakatochi, M , Wong, A , Hutri-Kahonen, N , Wu, Kuan-Han H. , Sim, X , Xia, R , Huerta-Chagoya, A , Fernandez-Lopez, JC , Lyssenko, V , Nongmaithem, SS , Sankareswaran, A , Irvin, MR , Oldmeadow, C , Kim, H-N , Ntalla, Ioanna , Ryu, S , Timmers, PRHJ , Arbeeva, L , Dorajoo, R , Lange, LA , Prasad, G , Lores-Motta, L , Pauper, M , Long, J , Li, X , Hui, Qin , Theusch, E , Takeuchi, F , Spracklen, CN , Loukola, A , Bollepalli, S , Warner, SC , Wang, YX , Wei, WB , Nutile, T , Ruggiero, D , Klarin, Derek , Sung, YJ , Chen, S , Liu, F , Kentistou, KA , Banas, B , Morgan, A , Meidtner, K , Bielak, LF , Smith, JA , Graham, Sarah E. , Hilliard, Austin T. , Hebbar, P , Farmaki, A-E , Hofer, E , Lin, M , Concas, MP , Vaccargiu, S , van der Most, PJ , Pitkanen, N , Cade, BE , van der Laan, SW , Wang, Z , Chitrala, KN , Weiss, S , Bentley, AR , Doumatey, AP , Adeyemo, AA , Lee, JY , Petersen, ERB , Nielsen, AA , Choi, HS , Nethander, M , Xue, C , Freitag-Wolf, S , Southam, L , Rayner, NW , Wang, Carol A. , Lin, S-Y , Wang, J-S , Couture, C , Lyytikainen, L-P , Nikus, K , Cuellar-Partida, G , Thorleifsson, G , Vestergaard, H , Hidalgo, B , Giannakopoulou, O , Cai, Q , Obura, MO , van Setten, J , He, KY , Tang, H , Terzikhan, N , Shin, JH , Helgadottir, A , Jackson, RD , Reiner, AP , Martin, LW , Chen, Z , Li, L , Kawaguchi, T , Thiery, J , Bis, JC , Launer, LJ , Li, H , Gudbjartsson, DF , Nalls, MA , Raitakari, OT , Ichihara, S , Wild, SH , Nelson, CP , Campbell, H , Jager, S , Nabika, T , Al-Mulla, F , Niinikoski, H , Holm, H , Braund, PS , Kolcic, I , Kovacs, P , Giardoglou, T , Katsuya, T , de Kleijn, D , de Borst, GJ , Kim, EK , Adams, HHH , Ikram, MA , Olafsson, I , Zhu, X , Asselbergs, FW , Kraaijeveld, AO , Beulens, JWJ , Shu, X-O , Rallidis, LS , Pedersen, O , Hansen, T , Mitchell, P , Hewitt, AW , Hwang, MY , Kahonen, M , Perusse, L , Bouchard, C , Tonjes, A , Chen, Y-DI , Pennell, CE , Mori, TA , Lieb, W , Franke, A , Ohlsson, C , Han, S , Mellstrom, D , Cho, YS , Lee, H , Yuan, J-M , Koh, W-P , Rhee, SY , Woo, J-T , Heid, IM , Stark, KJ , Zimmermann, ME , Kanoni, Stavroula , Akiyama, M , Volzke, H , Homuth, G , Evans, MK , Zonderman, AB , Polasek, O , Pasterkamp, G , Hoefer, IE , Redline, S , Pahkala, K , Oldehinkel, AJ , Sakaue, S , Snieder, H , Biino, G , Schmidt, R , Schmidt, H , Bandinelli, S , Dedoussis, G , Thanaraj, TA , Peyser, PA , Kato, N , Schulze, MB , Terao, C , Girotto, G , Boger, CA , Jung, B , Joshi, PK , Bennett, DA , De Jager, PL , Lu, X , Mamakou, V , Brown, M , Caulfield, MJ , Kanai, M , Munroe, PB , Guo, X , Ciullo, M , Jonas, JB , Samani, NJ , Kaprio, J , Pajukanta, P , Tusie-Luna, T , Aguilar-Salinas, CA , Adair, LS , Zhou, W , Bechayda, SA , de Silva, HJ , Wickremasinghe, AR , Krauss, RM , Wu, J-Y , Zheng, W , den Hollander, A , Bharadwaj, D , Correa, A , Wilson, JG , Brumpton, BM , Lind, L , Heng, C-K , Nelson, AE , Golightly, YM , Wilson, JF , Penninx, B , Kim, H-L , Attia, John , Scott, RJ , Rao, DC , Rasheed, H , Arnett, DK , Walker, M , Scott, LJ , Koistinen, HA , Chandak, GR , Mercader, JM , Villalpando, CG , Orozco, L , Fornage, M , Tai, ES , Havulinna, AS , van Dam, RM , Lehtimaki, T , Chaturvedi, N , Yokota, M , Reilly, DF , McKnight, AJ , Kee, F , Jockel, K-H , McCarthy, M , Veturi, Y , Palmer, CNA , Vitart, V , Hayward, C , Simonsick, E , van Duijn, CM , Jin, Z-B , Lu, F , Hishigaki, H , Lin, X , Marz, W , Pacheco, JA , Gudnason, V , Tardif, J-C , Lettre, G , Hart, LMT , Elders, PJM , Rader, DJ , Damrauer, SM , Kumari, M , Kivimaki, M , van der Harst, P , Wang, Yuxuan , Rosenthal, EA , Spector, TD , Loos, RJF , Province, MA , Parra, EJ , Cruz, M , Psaty, BM , Brandslund, I , Pramstaller, PP , Rotimi, CN , Christensen, K , Lingren, T , Ripatti, S , Widen, E , Hakonarson, H , Grant, SFA , Kiemeney, L , de Graaf, J , Loeffler, M , Kronenberg, F , Gu, D , Erdmann, J , Feng, Q , Schunkert, H , Franks, PW , Linneberg, A , Jukema, JW , Khera, A , Mannikko, M , Jarvelin, M-R , Kutalik, Z , Francesco, C , Mook-Kanamori, DO , Kullo, IJ , van Dijk, KW , Watkins, H , Strachan, DP , Grarup, N , Sever, P , Poulter, N , Sheu, WH-H , Rotter, J , Dantoft, TM , Karpe, F , Narita, A , Neville, MJ , Timpson, NJ , Cheng, C-Y , Wong, T-Y , Khor, CC , Sabanayagam, C , Peters, A , Gieger, C , Hattersley, AT , Takayama, J , Pedersen, NL , Magnusson, PKE , Boomsma, D , de Geus, EJC , Cupples, LA , van Meurs, JBJ , Ikram, A , Ghanbari, M , Gordon-Larsen, P , Huang, W , Martin, HC , Kim, YJ , Tabara, Y , Wareham, NJ , Langenberg, C , Zeggini, E , Tuomilehto, J , Kuusisto, J , Laakso, M , Ingelsson, E , Abecasis, G , Hunt, KA , Chambers, JC , Kooner, JS , de Vries, PS , Morrison, AC , Hazelhurst, S , Ramsay, M , North, KE , Daviglus, M , Kraft, P , Martin, NG , Trivedi, B , Whitfield, JB , Abbas, S , Saleheen, D , Walters, RG , Holmes, M , Black, C , Smith, BH , Baras, A , Justice, AE , Buring, JE , Haessler, J , Ridker, PM , Chasman, D , Kooperberg, C , Tamiya, G , Yamamoto, M , van Heel, DA , Trembath, RC , Wei, W-Q , Jarvik, GP , Namjou, B , Surakka, Ida , Giulianini, F , Hayes, MG , Ritchie, MD , Jousilahti, P , Salomaa, V , Hveem, K , Asvold, BO , Kubo, M , Kamatani, Y , Okada, Y , Murakami, Y , Bradford, Y , Kim, B-J , Thorsteinsdottir, U , Stefansson, K , Zhang, J , Chen, YE , Ho, Y-L , Lynch, JA , Tsao, PS , Chang, K-M , Cho, K , Miller, JE , O'Donnell, CJ , Gaziano, JM , Wilson, P , Mohlke, KL , Frayling, TM , Hirschhorn, JN , Kathiresan, S , Boehnke, M , Grant, S , Natarajan, P , Campbell, A , Sun, Y , Morris, AP , Deloukas, P , Peloso, G , Assimes, TL , Willer, CJ , Brown, CD , Lin, K , Millwood, IY , Rasheed, A , Hindy, G , Faul, JD , Zhao, W , Wenz, Brandon , Weir, DR , Turman, C , Huang, H , Graff, M , Choudhury, A , Sengupta, D , Mahajan, A , Brown, MR , Zhang, W , Yu, K , Clarke, Shoa L. , Schmidt, EM , Pandit, A , Gustafsson, S , Yin, X , Luan, J , Zhao, J-H , Matsuda, F , Jang, H-M , Yoon, K , Medina-Gomez, C , Chesi, Alessandra , Pitsillides, A , Hottenga, JJ , Wood, AR , Ji, Y , Gao, Z , Haworth, S , Mitchell, RE , Chai, JF , Aadahl, M , Bjerregaard, AA , Wells, Andrew , Yao, J , Manichaikul, A , Lee, W-J , Hsiung, CA , Warren, HR , Ramirez, J , Bork-Jensen, J , Karhus, LL , Goel, A , Sabater-Lleal, M
- Resource Type: journal article
- Date: 2022
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
- Creator: Kanoni, Stavroula , Graham, Sarah E. , Locke, Adam E. , Matteo, F , McDaid, AF , Marques-Vidal, P , Wielscher, M , Trompet, S , Sattar, N , Mollehave, LT , Munz, M , Zeng, L , Huang, J , Marouli, Eirini , Yang, B , Poveda, A , Kurbasic, A , Lamina, C , Forer, L , Scholz, M , Galesloot, TE , Bradfeld, JP , Ruotsalainen, SE , Daw, E , Zajac, Greg J. M. , Zmuda, JM , Mitchell, JS , Fuchsberger, C , Christensen, H , Brody, JA , Vazquez-Moreno, M , Feitosa, MF , Wojczynski, MK , Wang, Z , Preuss, MH , Wu, Kuan-Han H. , Mangino, M , Christofdou, P , Verweij, N , Benjamins, JW , Engmann, J , Tsao, NL , Verma, A , Slieker, RC , Lo, KS , Zilhao, NR , Ntalla, Ioanna , Le, P , Kleber, ME , Delgado, GE , Huo, S , Ikeda, DD , Iha, H , Yang, J , Liu, J , Leonard, HL , Marten, J , Hui, Qin , Frank, M , Schmidt, B , Smyth, LJ , Canadas-Garre, M , Wang, Carol A. , Nakatochi, M , Wong, A , Hutri-Kahonen, N , Sim, X , Xia, R , Klarin, Derek , Huerta-Chagoya, A , Fernandez-Lopez, JC , Lyssenko, V , Nongmaithem, SS , Bayyana, S , Stringham, HM , Irvin, MR , Oldmeadow, C , Kim, H-N , Ryu, S , Hilliard, Austin T. , Timmers, PRHJ , Arbeeva, L , Dorajoo, R , Lange, LA , Prasad, G , Lores-Motta, L , Pauper, M , Long, J , Li, X , Theusch, E , Wang, Zeyuan , Takeuchi, F , Spracklen, CN , Loukola, A , Bollepalli, S , Warner, SC , Wang, YX , Wei, WB , Nutile, T , Ruggiero, D , Sung, YJ , Xue, Chao , Chen, S , Liu, F , Kentistou, KA , Banas, B , Nardone, GG , Meidtner, K , Bielak, LF , Smith, JA , Hebbar, P , Wang, Yuxuan , Thorleifsson, Gudmar , Farmaki, A-E , Hofer, E , Lin, M , Concas, MP , Vaccargiu, S , van der Most, PJ , Pitkanen, N , Cade, BE , van der Laan, SW , Chitrala, KN , Helgadottir, A , Weiss, S , Bentley, AR , Doumatey, AP , Adeyemo, AA , Lee, JY , Petersen, ERB , Nielsen, AA , Choi, HS , Nethander, M , Freitag-Wolf, S , Gudbjartsson, DF , Southam, L , Rayner, NW , Wang, CA , Lin, S-Y , Wang, J-S , Couture, C , Lyytikainen, L-P , Nikus, K , Cuellar-Partida, G , Vestergaard, H , Holm, H , Hidalgo, B , Giannakopoulou, O , Cai, Q , Obura, MO , van Setten, J , Liang, J , Tang, H , Terzikhan, N , Shin, JH , Olafsson, I , Jackson, RD , Reiner, AP , Martin, LW , Chen, Z , Li, L , Kawaguchi, T , Thiery, J , Bis, JC , Launer, LJ , Li, H , Hwang, MY , Nalls, MA , Raitakari, OT , Ichihara, S , Wild, SH , Nelson, CP , Campbell, H , Jager, S , Nabika, T , Al-Mulla, F , Niinikoski, H , Han, S , Braund, PS , Kolcic, I , Kovacs, P , Giardoglou, T , Katsuya, T , de Kleijn, D , de Borst, GJ , Kim, EK , Adams, HHH , Ikram, MA , Akiyama, M , Zhu, X , Asselbergs, FW , Kraaijeveld, AO , Beulens, JWJ , Shu, X-O , Rallidis, LS , Pedersen, O , Hansen, T , Mitchell, P , Hewitt, AW , Sakaue, S , Kahonen, M , Perusse, L , Bouchard, C , Tonjes, A , Chen, Y-DI , Pennell, Craig E. , Mori, TA , Lieb, W , Franke, A , Ohlsson, C , Terao, C , Mellstrom, D , Cho, YS , Lee, H , Yuan, J-M , Koh, W-P , Rhee, SY , Woo, J-T , Heid, IM , Stark, KJ , Zimmermann, ME , Surakka, Ida , Kanai, M , Volzke, H , Homuth, G , Evans, MK , Zonderman, AB , Polasek, O , Pasterkamp, G , Hoefer, IE , Redline, S , Pahkala, K , Oldehinkel, AJ , Zhou, W , Snieder, H , Biino, G , Schmidt, R , Schmidt, H , Bandinelli, S , Dedoussis, G , Thanaraj, TA , Kardia, SLR , Peyser, PA , Kato, N , Brumpton, BM , Schulze, MB , Girotto, G , Boger, CA , Jung, B , Joshi, PK , Bennett, DA , De Jager, PL , Lu, X , Mamakou, V , Brown, M , Rasheed, H , Caulfeld, MJ , Munroe, PB , Guo, X , Ciullo, M , Jonas, JB , Samani, NJ , Kaprio, J , Pajukanta, P , Tusie-Luna, T , Aguilar-Salinas, CA , Havulinna, AS , Adair, LS , Bechayda, SA , de Silva, HJ , Wickremasinghe, AR , Krauss, RM , Wu, J-Y , Zheng, W , Hollander, AI , Bharadwaj, D , Correa, A , Veturi, Y , Wilson, JG , Lind, L , Heng, C-K , Nelson, AE , Golightly, YM , Wilson, JF , Penninx, B , Kim, H-L , Attia, John , Scott, RJ , Pacheco, JA , Rao, DC , Arnett, DK , Hunt, SC , Walker, M , Koistinen, HA , Chandak, GR , Mercader, JM , Costanzo, MC , Jang, D , Burtt, NP , Rosenthal, EA , Villalpando, CG , Orozco, L , Fornage, M , Tai, E , van Dam, RM , Lehtimaki, T , Chaturvedi, N , Yokota, M , Reilly, DF , Lingren, T , McKnight, AJ , Kee, F , Jockel, K-H , McCarthy, M , Palmer, CNA , Vitart, V , Hayward, C , Simonsick, E , van Duijn, CM , Jin, Z-B , Feng, Q , Qu, J , Hishigaki, H , Lin, X , Marz, W , Gudnason, V , Tardif, J-C , Lettre, G , t Hart, LM , Elders, PJM , Damrauer, SM , Ramdas, Shweta , Kullo, IJ , Kumari, M , Kivimaki, M , van der Harst, P , Spector, TD , Loos, RJF , Province, MA , Parra, EJ , Cruz, M , Psaty, BM , Brandslund, I , Narita, A , Pramstaller, PP , Rotimi, CN , Christensen, K , Ripatti, S , Widen, E , Hakonarson, H , Grant, SFA , Kiemeney, LALM , de Graaf, J , Loefer, M , Takayama, J , Kronenberg, F , Gu, D , Erdmann, J , Schunkert, H , Franks, PW , Linneberg, A , Jukema, JW , Khera, A , Mannikko, M , Jarvelin, M-R , Martin, HC , Kutalik, Z , Francesco, C , Mook-Kanamori, DO , van Dijk, KW , Watkins, H , Strachan, DP , Grarup, N , Sever, P , Poulter, N , Chuang, L-M , Hunt, KA , Rotter, J , Dantoft, TM , Karpe, F , Neville, MJ , Timpson, NJ , Cheng, C-Y , Wong, T-Y , Khor, CC , Sabanayagam, C , Trivedi, B , Peters, A , Gieger, C , Hattersley, AT , Pedersen, NL , Magnusson, PKE , Boomsma, D , Willemsen, AHM , Cupples, L , van Meurs, JBJ , Ghanbari, M , Haessler, J , Gordon-Larsen, P , Huang, W , Kim, YJ , Tabara, Y , Wareham, NJ , Langenberg, C , Zeggini, E , Kuusisto, J , Laakso, M , Ingelsson, E , Giulianini, F , Abecasis, G , Chambers, JC , Kooner, JS , de Vries, PS , Morrison, AC , Hazelhurst, S , Ramsay, M , North, KE , Daviglus, M , Kraft, P , Bradford, Y , Martin, NG , Whitfeld, JB , Abbas, S , Saleheen, D , Walters, RG , Holmes, M , Black, C , Smith, BH , Baras, A , Justice, AE , Miller, JE , Buring, JE , Ridker, PM , Chasman, D , Kooperberg, C , Tamiya, G , Yamamoto, M , van Heel, DA , Trembath, RC , Wei, W-Q , Jarvik, GP , Zhu, Xiang , Campbell, A , Namjou, B , Hayes, MG , Ritchie, MD , Jousilahti, P , Salomaa, V , Hveem, K , Asvold, BO , Kubo, M , Kamatani, Y , Okada, Y , Lin, K , Murakami, Y , Kim, B-J , Thorsteinsdottir, U , Stefansson, K , Zhang, J , Chen, YE , Ho, Y-L , Lynch, JA , Rader, DJ , Tsao, PS , Millwood, IY , Chang, K-M , Cho, K , O'Donnell, CJ , Gaziano, JM , Wilson, PWF , Frayling, TM , Hirschhorn, JN , Kathiresan, S , Mohlke, KL , Sun, Y , Rasheed, A , Morris, AP , Boehnke, M , Brown, CD , Natarajan, P , Deloukas, P , Willer, CJ , Assimes, TL , Peloso, GM , Demirkan, A , Hindy, G , Faul, JD , Zhao, W , Weir, DR , Turman, C , Huang, H , Clarke, Shoa L. , Graf, M , Choudhury, A , Sengupta, D , Mahajan, A , Brown, MR , Zhang, W , Yu, K , Schmidt, EM , Pandit, A , Gustafsson, S , Bhatti, Konain Fatima , Yin, X , Luan, J , Zhao, J-H , Matsuda, F , Jang, H-M , Yoon, K , Medina-Gomez, C , Pitsillides, A , Hottenga, JJ , Wood, AR , Vedantam, Sailaja , Ji, Y , Gao, Z , Haworth, S , Yousri, NA , Mitchell, RE , Chai, JF , Aadahl, M , Bjerregaard, AA , Yao, J , Manichaikul, A , Winkler, Thomas W. , Hwu, C-M , Hung, Y-J , Warren, HR , Ramirez, J , Bork-Jensen, J , Karhus, LL , Goel, A , Sabater-Lleal, M , Noordam, R , Mauro, P
- Resource Type: journal article
- Date: 2022