A comparison of in vivo viral targeting systems identifies adeno-associated virus serotype 9 (AAV9) as an effective vector for genetic manipulation of Leydig cells in adult mice

- Darbey, Annalcuia, Rebourcet, Diane, Curley, Michael, Kilcoyne, Karen, Jeffery, Nathan, Reed, Natalie, Milne, Laura, Roesl, Cornelia, Brown, Pamela, Smith, Lee B.

A graphical and computational modeling platform for biological pathways

- Livigni, Alessandra, O'Hara, Laura, Polak, Marta E., Angus, Tim, Wright, Derek W., Smith, Lee B., Freeman, Tom C.

Androgen receptor expression is required to ensure development of adult Leydig cells and to prevent development of steroidogenic cells with adrenal characteristics in the mouse testis

- O'Shaughnessy, Peter J., Mitchell, Rod T., Monteiro, Ana, O'Hara, Laura, Cruickshanks, Lyndsey, Claahsen-van der Grinten, Hedi, Brown, Pamela, Abel, Margaret, Smith, Lee B.

Androgen receptor signalling in the male adrenal facilitates X-zone regression, cell turnover and protects against adrenal degeneration during ageing

- Gannon, Anne-Louise, O'Hara, Laura, Mason, J. Ian, Jørgensen, Anne, Frederiksen, Hanne, Milne, Laura, Smith, Sarah, Mitchell, Rod T., Smith, Lee B.

Bi-allelic recessive loss-of-function variants in FANCM cause non-obstructive azoospermia

- Kasak, Laura, Punab, Margus, Smith, Lee B., Conrad, Donald F., Laan, Maris, Nagirnaja, Liina, Grigorova, Marina, Minajeva, Ave, Lopes, Alexandra M., Punab, Anna Maria, Aston, Kenneth I., Carvalho, Filipa, Laasik, Eve

Characterisation of a mural cell network in the murine pituitary gland

- O'Hara, Laura, Christian, Helen C., Jeffery, Nathan, Le Tissier, Paul, Smith, Lee B.

Deciphering cell lineage specification during male sex determination with single-cell RNA sequencing

- Stévant, Isabelle, Neirijnck, Yasmine, Borel, Christelle, Escoffier, Jessica, Smith, Lee B., Antonarakis, Stylianos E., Dermitzakis, Emmanouil T., Nef, Serge

DMRT1 repression using a novel approach to genetic manipulation induces testicular dysgenesis in human fetal gonads

- Macdonald, Joni, Kilcoyne, Karen R., Sharpe, Richard M., Kavanagh, Áine, Anderson, Richard A., Brown, Pamela, Smith, Lee B., Jørgensen, Anne, Mitchell, Rod T.

Leukemia inhibitory factor-receptor is dispensable for prenatal testis development but is required in sertoli cells for normal spermatogenesis in mice

- Curley, Michael, Milne, Laura, Smith, Sarah, Atanassova, Nina, Rebourcet, Diane, Darbey, Annalucia, Hadoke, Patrick W. F., Wells, Sara, Smith, Lee B.

Low-dose tamoxifen treatment in juvenile males has long-term adverse effects on the reproductive system: implications for inducible transgenics

- Patel, Saloni H., O'Hara, Laura, Atanassova, Nina, Smith, Sarah E., Curley, Michael K., Rebourcet, Diane, Darbey, Annalucia L., Gannon, Anne-Louise, Sharpe, Richard M., Smith, Lee B.

Modelling steroidogenesis: a framework model to support hypothesis generation and testing across endocrine studies

- O'Hara, Laura, O'Shaughnessy, Peter J., Freeman, Tom C., Smith, Lee B.

Pleiotropic impacts of macrophage and microglial deficiency on development in rats with targeted mutation of the Csf1r locus

- Pridans, Clare, Raper, Anna, Davis, Gemma M., Alves, Joana, Sauter, Kristin A., Lefevre, Lucas, Regan, Tim, Meek, Stephen, Sutherland, Linda, Thomson, Alison J., Clohisey, Sara, Bush, Stephen J., Rojo, Rocío, Lisowski, Zofia M., Wallace, Robert, Grabert, Kathleen, Upton, Kyle R., Tsai, Yi Ting, Brown, Deborah, Smith, Lee B.

Reconstitution of rat fetal testis during the masculinisation programming window induces focal dysgenesis consistent with testicular dysgenesis syndrome

- Smart, Ellie, Macdonald, Joni, Smith, Lee B., Mitchell, Rod T.

Sertoli cell number defines and predicts germ and Leydig cell population sizes in the adult mouse testis

- Rebourcet, Diane, Darbey, Annalucia, Monteiro, Ana, Soffientini, Ugo, Tsai, Yi Ting, Handel, Ian, Pitetti, Jean-Luc, Nef, Serge, Smith, Lee B., O'Shaughnessy, Peter J.

The expanded roles of Sertoli cells: lessons from Sertoli cell ablation models

- Rebourcet, Diane, O'Shaughnessy, Peter J., Smith, Lee B.

Xenotransplantation as a model for human testicular development

- Hutka, Marsida, Smith, Lee B., Mitchell, Rod T.