Methyl donor supplementation reduces phospho-Tau, Fyn and demethylated protein phosphatase 2A levels and mitigates learning and motor deficits in a mouse model of tauopathy
- Creator: van Hummel, Annika , Taleski, Goce , Sontag, Jean-Marie , Feiten, Astrid Feentje , Ke, Yazi D. , Ittner, Lars M. , Sontag, Estelle
- Resource Type: journal article
- Date: 2023
A new paradigm for regulation of protein phosphatase 2A function via Src and Fyn kinase–mediated tyrosine phosphorylation
- Creator: Sontag, Jean-Marie , Schuhmacher, Diana , Sontag, Estelle , Wadzinski, Brian E. , Taleski, Goce , Jordan, Anthony , Khan, Sarah , Hoffman, Alexander , Gomez, Rey J. , Mazalouskas, Matthew D. , Hanks, Steven K. , Spiller, Benjamin W.
- Resource Type: journal article
- Date: 2022
Disturbances in PP2A methylation and one-carbon metabolism compromise Fyn distribution, neuritogenesis, and APP regulation
- Creator: Taleski, Goce , Schuhmacher, Diana , Su, Henry , Sontag, Jean-Marie , Sontag, Estelle
- Resource Type: journal article
- Date: 2021
The deregulation of Fyn kinase in Alzheimer's Disease
- Creator: Taleski, Goce
- Resource Type: thesis
- Date: 2021
Methylenetetrahydrofolate Reductase Deficiency Deregulates Regional Brain Amyloid-β Protein Precursor Expression and Phosphorylation Levels
- Creator: Hoffman, Alexander , Taleski, Goce , Qian, Helena , Wasek, Brandi , Arning, Erland , Bottiglieri, Teodoro , Sontag, Jean-Marie , Sontag, Estelle
- Resource Type: journal article
- Date: 2018
Protein phosphatase 2A and tau: an orchestrated 'Pas de Deux'
- Creator: Taleski, Goce , Sontag, Estelle
- Resource Type: journal article
- Date: 2018
The protein serine/threonine phosphatases PP2A, PP1 and calcineurin: a triple threat in the regulation of the neuronal cytoskeleton
- Creator: Hoffman, Alexander , Taleski, Goce , Sontag, Estelle
- Resource Type: journal article
- Date: 2017
Altered protein phosphatase 2A methylation and Tau phosphorylation in the young and aged brain of methylenetetrahydrofolate reductase (MTHFR) deficient mice
- Creator: Sontag, Jean-Marie , Wasek, Brandi , Taleski, Goce , Smith, Josephine , Arning, Erland , Sontag, Estelle , Bottiglieri, T
- Resource Type: journal article
- Date: 2014