Embryo number and periconceptional undernutrition in the sheep have differential effects on adrenal epigenotype, growth, and development
- Creator: Williams-Wyss, Olivia , Zhang, Song , MacLaughlin, Severence M. , Kleemann, David , Walker, Simon K. , Suter, Catherine M. , Cropley, Jennifer E. , Morrison, Janna L. , Roberts, Claire T. , McMillen, I. Caroline
- Resource Type: journal article
- Date: 2014
Dietary restriction in the periconceptional period in normal-weight or obese ewes results in increased abundance of angiotensin-converting enzyme (ACE) and angiotensin type 1 receptor (AT1R) in the absence of changes in ACE or AT1R methylation in the adrenal of the offspring
- Creator: Zhang, Song , Morrison, Janna L. , Gill, Amreet , Rattanatray, Leewen , MacLaughlin, Severence , Kleemann, David , Walker, Simon K. , McMillen, I. Caroline
- Resource Type: journal article
- Date: 2013
Maternal dietary restriction during the periconceptional period in normal-weight or obese ewes results in adrenocortical hypertrophy, an up-regulation of the JAK/STAT and down-regulation of the IGF1R signaling pathways in the adrenal of the postnatal lamb
- Creator: Zhang, Song , Morrison, Janna L. , Gill, Amreet , Rattanatray, Leewen , MacLaughlin, Severence M. , Kleemann, David , Walker, Simon K. , McMillen, I. Caroline
- Resource Type: journal article
- Date: 2013